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Epigenetics & Stem Cell Biology Laboratory

Trevor K. Archer, Ph.D.
Trevor K. Archer, Ph.D.
Chief, Epigenetics & Stem Cell Biology Laboratory and Principal Investigator
Tel (919) 316-4565
Fax (919) 316-4566
archer1@niehs.nih.gov
P.O. Box 12233
Mail Drop D4-01
Research Triangle Park, North Carolina 27709
Delivery Instructions
Paul A. Wade, Ph.D.
Paul Wade, Ph.D.
Deputy Chief, Epigenetics & Stem Cell Biology Laboratory and Principal Investigator
Tel (919) 541-3392
Fax (919) 541-0146
wadep2@niehs.nih.gov
P.O. Box 12233
Mail Drop D4-04
Research Triangle Park, North Carolina 27709
Delivery Instructions

Research Summary

The Epigenetics and Stem Cell Biology Laboratory investigates fundamental mechanisms by which epigenetics — non-genetic modulation and alterations — influences chromatin architecture, transcription and gene expression in normal, cancer and embryonic stem cells and provides insights into biological processes that modulate the effects of environmental exposures. It also focuses on the molecular basis of self-renewal and pluripotency in embryonic stem (ES) cells and induced pluripotency stem (iPS) cells, as well as gene regulatory pathways using genomic, molecular, biochemical, computational and structural approaches.

In addition to the cutting edge hypothesis driven research of its investigators the laboratory provides leadership and support to the NIEHS in areas of genomics, epigenomics, mass spectrometry, and bioinformatics analyses. These endeavors build and research strengths established in the prior Laboratory of Molecular Carcinogenesis and extend the scope of the research beyond cancer to examine a broad range of environmental impacts on human health and development.

Scientific Support Staff

Kathleen Ochoa
Administrative Specialist
Tel (919) 541-0350
ochoak@niehs.nih.gov
Vivian G. Young
Administrative Technician
Tel (919) 541-2227
vivian.young@nih.gov
Timothy J. Hinton
Administrative Technician
Tel (919) 541-7797
hintont2@niehs.nih.gov

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