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TRlad Multi-Maker

The TRIad Multi-Marker (TRIMM) program performs max_Z2, and sum_log(P) tests, association tests for a child's or mother's genetic effects using multiple markers from triad families. Statistical significance is evaluated via permutation. It also outputs the nominated risk-haplotype-tagging alleles. For details, see Shi M, Umbach DM ,Weinberg CR "Identification of Risk-related Haplotypes Using Multiple SNPs from Nuclear Families".

 

Download

 

trimm.zip(27KB) is the ZIPPED set of the following 5 files:

 

  • R source code: TRIMM.r
  • Program documentation: TRIMM_Documentation.pdf
  • 3 Example files: geno.m geno.f geno.c

 

Contact

Min Shi, M.D., Ph.D.
Tel (919) 541-3256
Fax (919) 541-4311
shi2@niehs.nih.gov
David M. Umbach, Ph.D.
Tel (919) 541-4939
umbach@niehs.nih.gov
Clarice R. Weinberg, Ph.D.
Tel (919) 541-4927
Fax (919) 541-4311
weinberg@niehs.nih.gov

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