TRlad Multi-Maker
The TRIad Multi-Marker (TRIMM) program performs max_Z2, and sum_log(P) tests, association tests for a child's or mother's genetic effects using multiple markers from triad families. Statistical significance is evaluated via permutation. It also outputs the nominated risk-haplotype-tagging alleles. For details, see Shi M, Umbach DM ,Weinberg CR "Identification of Risk-related Haplotypes Using Multiple SNPs from Nuclear Families".
Download
trimm.zip
(27KB)
is the ZIPPED set of the following 5 files:
- R source code: TRIMM.r
- Program documentation: TRIMM_Documentation.pdf
- 3 Example files: geno.m geno.f geno.c
Contact
- Min Shi, M.D., Ph.D. (http://www.niehs.nih.gov/research/atniehs/labs/bb/staff/minshi/index.cfm)
-
Tel (919) 541-3256
Fax (919) 541-4311
shi2@niehs.nih.gov
- David M. Umbach, Ph.D. (http://www.niehs.nih.gov/research/atniehs/labs/bb/staff/umbach/index.cfm)
-
Tel (919) 541-4939
Fax (919) 541-4311
umbach@niehs.nih.gov
- Clarice R. Weinberg, Ph.D. (http://www.niehs.nih.gov/research/atniehs/labs/bb/staff/weinberg/index.cfm)
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Tel (919) 541-4927
Fax (919) 541-4311
weinber2@niehs.nih.gov
