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Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

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Molecular Toxicology & Genomics Group

Julie F. Foley
Julie F. Foley
Health Scientist
Tel 984-287-3129
[email protected]
P.O. Box 12233
Mail Drop E0-01
Durham, NC 27709

Julie F. Foley is a Health Scientist in the NIEHS Division of Translational Toxicology.

Foley Group Graphic

In her current role, Foley is involved in working with the NTP Biorepository and Cellular and Molecular Pathology Branch to implement a sample tracking, management, and freezer inventory software program. This will enable the NTP to be better able to deposit and manage NTP samples for future molecular analysis. She is involved with the development of new technologies to assist with toxicity screening and carcinogen classification. Novel screening technologies include a BSB led effort to develop a rat whole exome probe set. Rat exome capture will allow for mutation analysis of frozen and paraffin blocked samples (FFPE – formalin fixed, paraffin embedded) with samples anchored in diagnostic pathology. Another initiative includes investigation of circulating plasma markers for the early detection of inflammation and its possible link with long term toxicity and carcinogenic events in chemical bioassay studies. In addition, Foley is in training as a contract officer representative (COR) to assist in managing contracts in BSB.

Prior to joining the Molecular Toxicology and Genomics Group, Foley was a member of the Cellular and Molecular Pathology Branch within the NTP where she was Group Leader of the Special Techniques Group which provided pathology support core services in the areas of mouse embryo phenotyping, laser microdissection, image analysis and special miscellaneous techniques involving tissue collection and handling.

Foley obtained a B.S. in Biology from East Carolina University and a B.S. from Duke University in the Allied Health Science Program as a Pathology Assistant.

Recent Publications

  1. Foley JF, Elgart B, Alex Merrick B, Phadke DP, Cook ME, Malphurs JA, Solomon GG, Shah RR, Fessler MB, Miller FW, Gerrish KE. 2021. Whole genome sequencing of low input circulating cell-free DNA obtained from normal human subjects. Physiol Rep 9(15):e14993. [Abstract Foley JF, Elgart B, Alex Merrick B, Phadke DP, Cook ME, Malphurs JA, Solomon GG, Shah RR, Fessler MB, Miller FW, Gerrish KE. 2021. Whole genome sequencing of low input circulating cell-free DNA obtained from normal human subjects. Physiol Rep 9(15):e14993.]
  2. Dunnick, J.K., Merrick, B.A., Brix, A., Morgan, D.L., Gerrish, K., Wang, Y., Flake, G., Foley, J., Shockley, K.R. Molecular changes in the nasal cavity after N,N-Dimethyl-p-toluidine exposure. Toxicol. Path. 44(6), 835-847, 2016. [Abstract Dunnick, J.K., Merrick, B.A., Brix, A., Morgan, D.L., Gerrish, K., Wang, Y., Flake, G., Foley, J., Shockley, K.R. Molecular changes in the nasal cavity after N,N-Dimethyl-p-toluidine exposure. Toxicol. Path. 44(6), 835-847, 2016.]
  3. Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice. Endocrinology 2016 157(7):2759-2771. [Abstract Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice. Endocrinology 2016 157(7):2759-2771.]
  4. Swartley OM, Foley JF, Livingston DP, Sabio DA, Cullen JM, Elmore SA. Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development. Journal of toxicologic pathology 2016 44(5):705-725. [Abstract Swartley OM, Foley JF, Livingston DP, Sabio DA, Cullen JM, Elmore SA. Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development. Journal of toxicologic pathology 2016 44(5):705-725.]
  5. Tucker DK, Foley JF, Hayes-Bouknight SA, Fenton SE. 2016. Preparation of high-quality hematoxylin and eosin-stained sections from rodent mammary gland whole mounts for histopathologic review. Toxicol Pathol 44(7):1059-64. [Abstract Tucker DK, Foley JF, Hayes-Bouknight SA, Fenton SE. 2016. Preparation of high-quality hematoxylin and eosin-stained sections from rodent mammary gland whole mounts for histopathologic review. Toxicol Pathol 44(7):1059-64.]
  6. Filgo AJ, Foley JF, Puvanesarajah S, Borde AR, Midkiff BR, Reed CE, Chappell VA, Alexander LB, Borde PR, Troester MA, Bouknight SA, Fenton SE. 2016. Mammary gland evaluation in juvenile toxicity studies: temporal developmental patterns in the male and female Harlan Sprague-Dawley rat. Toxicol Pathol 44(7):1034-58. [Abstract Filgo AJ, Foley JF, Puvanesarajah S, Borde AR, Midkiff BR, Reed CE, Chappell VA, Alexander LB, Borde PR, Troester MA, Bouknight SA, Fenton SE. 2016. Mammary gland evaluation in juvenile toxicity studies: temporal developmental patterns in the male and female Harlan Sprague-Dawley rat. Toxicol Pathol 44(7):1034-58.]
  7. Singh AP, Foley JF, Rubino M, Boyle MC, Tandon A, Shah R, Archer TK. 2016. Brg1 enables rapid growth of the early embryo by suppressing genes that regulate apoptosis and cell growth arrest. Mol Cell Biol 36(15):1990-2010. [Abstract Singh AP, Foley JF, Rubino M, Boyle MC, Tandon A, Shah R, Archer TK. 2016. Brg1 enables rapid growth of the early embryo by suppressing genes that regulate apoptosis and cell growth arrest. Mol Cell Biol 36(15):1990-2010.]
  8. Swartley OM, Foley JF, Livingston DP 3rd, Cullen JM, Elmore SA. 2016. Histology atlas of the developing mouse hepatobiliary hemolymphatic vascular system with emphasis on embryonic days 11.5-18.5 and early postnatal development. Toxicol Pathol 44(5):705-25. [Abstract Swartley OM, Foley JF, Livingston DP 3rd, Cullen JM, Elmore SA. 2016. Histology atlas of the developing mouse hepatobiliary hemolymphatic vascular system with emphasis on embryonic days 11.5-18.5 and early postnatal development. Toxicol Pathol 44(5):705-25.]
  9. Merrick BA, Auerbach SS, Stockton PS, Foley JF, Malarkey DE, Sills RC, Irwin RD, Tice RR. 2012. Testing an aflatoxin B1 gene signature in rat archival tissues. Chem Res Toxicol 25(5):1132-1144. [Abstract Merrick BA, Auerbach SS, Stockton PS, Foley JF, Malarkey DE, Sills RC, Irwin RD, Tice RR. 2012. Testing an aflatoxin B1 gene signature in rat archival tissues. Chem Res Toxicol 25(5):1132-1144.]
  10. Ward JM, Elmore SA, Foley JF. 2012. Pathology methods for the evaluation of embryonic and perinatal developmental defects and lethality in genetically engineered mice. Veterinary Pathology 49(1):71-84. [Abstract Ward JM, Elmore SA, Foley JF. 2012. Pathology methods for the evaluation of embryonic and perinatal developmental defects and lethality in genetically engineered mice. Veterinary Pathology 49(1):71-84.]
  11. Crawford LW, Foley JF, Elmore SA. 2010. Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5. Toxicol Pathol 38(6):872-906. [Abstract Crawford LW, Foley JF, Elmore SA. 2010. Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5. Toxicol Pathol 38(6):872-906.]
  12. Foley JF, Collins JB, Umbach DM, Grissom S, Boorman GA, Heinloth AN. 2006. Optimal sampling of rat liver tissue for toxicogenomic studies. Toxicol Pathol 34(6):795-801. [Abstract Foley JF, Collins JB, Umbach DM, Grissom S, Boorman GA, Heinloth AN. 2006. Optimal sampling of rat liver tissue for toxicogenomic studies. Toxicol Pathol 34(6):795-801.]