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Your Environment. Your Health.

mPopTag

mPopTag: The Multi-Population Tag SNP Picker

Developed by:

Zongli Xu, Norman Kaplan, and Jack A. Taylor
National Institute of Environmental Health
Division of Intramural Research Environmental Diseases, Medicine Epidemiology and Biostatistics Branches

The Multi-Population Tag Single Nucleotide Polymorphism (SNP) Picker (mPopTag) is a tool used to select or evaluate linkage disequilibrium (LD) tag SNPs for multiple populations. The program analyzes patterns of LD--measured by composite linkage disequilibrium (CLD) or r2--between polymorphic sites in a genome region for multiple populations. It also uses an agreedy algorithm to select a single set of near-minimum numbers of LD tag SNPs for multiple populations.

 

Downloads

Credits

The mPopTag was developed in and is maintained at the NIEHS by Zongli Xu, Norman L. Kaplan and Jack A Taylor.

 

Reference

Xu Z, Kaplan NL, Taylor JA. Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data. Eur J Hum Genet 2007 Oct;15(10):1063-70.

 

Installation

It can be run on Linux operating system.

 

Contact

Jack A. Taylor, M.D., Ph.D.
Tel (919) 541-4631
Fax (919) 541-2511
taylor@niehs.nih.gov
Zongli Xu, Ph.D.
Tel (919) 541-1677
Fax (919) 541-2511
xuz@niehs.nih.gov

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