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Workshop Report: Alternative Methods to Replace Animal Use for...
... Cellular, Tissue Ph.D., M.D. and Gene Therapies, U.S. Food and Drug Administration ... efforts directed towards antibody-based therapies 10 Workshop on Alternative Methods for ...
Size: 10.1MB https://ntp.niehs.nih.gov/iccvam/docs/biologics-docs/bontwkshprept.pdf -
RoC Background Document for Hepatitis C Virus; June 11, 2003
... Currently, HCV is treated by interferon-related therapies, and no vaccine is available. ... vaccines 2.4.1 Treatment In a review of therapies for HCV infection, McHutchison et al. ...
Size: 2.1MB https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc11/hcv_rg2public_508.pdf -
RoC Background Document on Human Papillomaviruses: Genital-Mucosal...
... topical applications, interferon-related therapies, laser methods, and surgical excision. ... warts include topical applications, surgical excision, and interferon-related therapies. ...
Size: 2.9MB https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc11/hpv_rg2_public_508.pdf -
OHAT Evaluation: Protocol for a Systematic Review to Evaluate...
... synthetic hormones (e.g., tamoxifen), monoclonal antibodies and other targeted therapies (e.g., imatinib) Comparator A comparison population exposed to lower levels (or no ...
Size: 1018KB https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/aheaoecca/protocol201510_508.pdf -
Protocol: Occupational Exposure to Cancer Chemotherapy Agents...
... synthetic hormones (e.g., tamoxifen), monoclonal antibodies and other targeted therapies (e.g., imatinib) Comparator A comparison population exposed to lower levels (or no ...
Size: 883KB https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/aheaoecca/protocol201812_508.pdf -
Background Document: RoC: Aristolochic Acids ; 2010
... In contemporary medicine, Aristolochia plant products have been used in therapies for ... In contemporary medicine, Aristolochia plant extracts have been used in therapies for ...
Size: 2.7MB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2010/finalbds/aristolochic_acids_final_508.pdf -
TOX-05: Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1...
... This practice has largely stopped because of associ- ated toxicity (gastrointestinal upset, goiter, car- diomyopathies) and the development of less haz- ardous therapies. It has ...
Size: 2.7MB https://ntp.niehs.nih.gov/sites/default/files/2023-08/tox05_508.pdf -
Minutes: SACATM Meeting, Sept. 2-3, 2020
... are used to study mechanisms underlying these diseases to suggest appropriate therapies. ... He closed by wondering about the practicality of using iPSCs to personalize drug therapies...
Size: 439KB https://ntp.niehs.nih.gov/sites/default/files/2025-09/minutessacatm20200902_508.pdf -
RoC Profile: Viruses: Eight Listings; 15th RoC 2021
... Janssen H. 2002. Combination and newer therapies for chronic hepatitis B. J Gastro- ... Currently, HCV is treated with interferon-based therapies, and no vaccine is available. ...
Size: 610KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/viruses.pdf -
NICEATM News Archive
... monoclonal antibody therapies and other drugs with more effective, human-relevant methods. ... Identify gaps in translation of these in silico models to therapies and seed discussions ...
https://ntp.niehs.nih.gov/whatwestudy/niceatm/publications-and-presentations/announcements-archive
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