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RoC Profile: Aristolochic Acids; 15th RoC 2021
... In contemporary medicine, Aristolochia plant extracts have been used in therapies for arthritis, gout, rheu- matism, and festering wounds, but these uses were discontinued in ...
Size: 182KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/aristolochicacids.pdf -
ICCVAM PF 2023 _230511_JM EB
... National Cancer Institute CAR-T cell therapies are ground-breaking, life-saving ... methods to evaluate the safety of these therapies, that have extraordinarily high risk for ...
Size: 191KB https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2023/pubcmts/pcrm20230512_508.pdf -
Nomination of MAT Test for Pyrogen Detection (April 2011)
... applicable to multiple agencies or programs Pyrogen testing is a crucial safety requirement for injectable drugs , eye drops , medical devices , cell therapies , baby food etc. ...
Size: 1.4MB https://ntp.niehs.nih.gov/iccvam/methods/pyrogen/mat-2011/iccvamnom-pyrodetecthk290311f-508.pdf -
Research Concept: Viruses; 2014
... At Risk Populations enveloped decreased t o 0 .63% (2010) with anti--- retroviral therapies e Merkel cell f virus (MCV) Polyoma virus Double---stranded DNA virus, non--- ...
Size: 331KB https://ntp.niehs.nih.gov/ntp/roc/concept_docs/2014/virusesconcept_508.pdf -
Public Comment - Physicians Committee for Responsible Medicine...
... areas of primate research and testing are replete with evidence of poor translation to human biology, disease, or benefit in the form of new, safe, and effective therapies. ...
Size: 229KB https://ntp.niehs.nih.gov/sites/default/files/2025-07/ICCVAM-PubForum-2025_PCRM-Comments_508.pdf -
ICCVAM Agency Activities
... monoclonal antibody therapies and other drugs with more effective, human-relevant methods. ... Identify gaps in translation of these in silico models to therapies and seed discussions ...
https://ntp.niehs.nih.gov/whatwestudy/niceatm/iccvam/agency-activities -
Assay Application
... alternating current or direct current therapies that use electrical stimulation to ... to determine the impact of low current stimulation, emulating transcranial therapies. ...
https://ntp.niehs.nih.gov/iccvamreport/2023/confidence/assay -
Assay Development
... EPA Endocrine Disruptors NIEHS Safety testing strategy for cell-based human cancer therapies Preclinical safety assessment for CAR T cell-based therapies is necessary because ...
https://ntp.niehs.nih.gov/iccvamreport/2023/technology/assay-dev -
RoC Monograph: Helicobacter pylori (Chronic Infection); October...
... Many different therapies are used in the United States, but the American College of ... OR intervention*[tiab] OR therapies[tiab] OR Therapy[tiab] OR ...
Size: 993KB https://ntp.niehs.nih.gov/ntp/roc/monographs/hpylori_final20181026_508.pdf -
Final Minutes: 2024 SACATM Meeting
... Three key areas of activity are: . Accelerating prevention efforts, new therapies, diagnostics, and potential cures. . Advancing global health and equity in care. . Training the ...
Size: 517KB https://ntp.niehs.nih.gov/sites/default/files/2024-12/2024_SACATM_minutes_final_508.pdf
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