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Nomination of MAT Test for Pyrogen Detection (April 2011)
... applicable to multiple agencies or programs Pyrogen testing is a crucial safety requirement for injectable drugs , eye drops , medical devices , cell therapies , baby food etc. ...
Size: 1.4MB https://ntp.niehs.nih.gov/iccvam/methods/pyrogen/mat-2011/iccvamnom-pyrodetecthk290311f-508.pdf -
ICCVAM Agency Activities
... monoclonal antibody therapies and other drugs with more effective, human-relevant methods. ... Identify gaps in translation of these in silico models to therapies and seed discussions ...
https://ntp.niehs.nih.gov/whatwestudy/niceatm/iccvam/agency-activities -
Research Concept: Cobalt; 2014
... Ingestion of excess vitamin (e.g., B12) supplements containing cobalt, prescribed cobalt therapies, and use of cobalt-containing prosthetics can all result in elevated exposure. ...
Size: 690KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/concept_docs/2014/cobalt_508.pdf -
Assay Application
... alternating current or direct current therapies that use electrical stimulation to ... to determine the impact of low current stimulation, emulating transcranial therapies. ...
https://ntp.niehs.nih.gov/iccvamreport/2023/confidence/assay -
Assay Development
... EPA Endocrine Disruptors NIEHS Safety testing strategy for cell-based human cancer therapies Preclinical safety assessment for CAR T cell-based therapies is necessary because ...
https://ntp.niehs.nih.gov/iccvamreport/2023/technology/assay-dev -
Research Concept: Viruses; 2014
... At Risk Populations enveloped decreased t o 0 .63% (2010) with anti--- retroviral therapies e Merkel cell f virus (MCV) Polyoma virus Double---stranded DNA virus, non--- ...
Size: 331KB https://ntp.niehs.nih.gov/ntp/roc/concept_docs/2014/virusesconcept_508.pdf -
TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered...
... to shift away from hormone-replacement therapies that can produce unwanted side effects. ... of plant-based therapies and menopausal symptoms: A systematic review and meta-analysis. ...
Size: 3.1MB https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf -
Final Minutes: 2024 SACATM Meeting
... Three key areas of activity are: . Accelerating prevention efforts, new therapies, diagnostics, and potential cures. . Advancing global health and equity in care. . Training the ...
Size: 517KB https://ntp.niehs.nih.gov/sites/default/files/2024-12/2024_SACATM_minutes_final_508.pdf -
NTP Monograph: Systematic Review of Occupational Exposure to...
... Antibiotics + + + + Hormone Therapies + + + + Mitotic Function Inhibitors ... (e.g., doxorubicin), hormone therapies (e.g., tamoxifen), mitotic function ...
Size: 6.2MB https://ntp.niehs.nih.gov/go/mgraph05 -
TOX-5: Cobalt Sulfate Heptahydrate CASRN 10026-24-1
... This practice has largely stopped because of associ- ated toxicity (gastrointestinal upset, goiter, car- diomyopathies) and the development of less haz- ardous therapies. It has ...
Size: 2.9MB https://ntp.niehs.nih.gov/go/tox005
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