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FNIH Overview for ICCVAM (ICCVAM 2024 Public Forum)
advance research that will lead to new therapies, diagnostics, and potential cures. 4 ... We advance global health & seek equity in care We accelerate prevention, new therapies, ...
Size: 4.8MB https://ntp.niehs.nih.gov/sites/default/files/2024-06/14_Conners_ICCVAMPublicForum2024_508.pdf -
Regulatory Applications of 3Rs
The U.S. Food and Drug Administration (FDA) has announced a plan to replace animal testing in the development of monoclonal antibody therapies and other drugs with more effective, ...
https://ntp.niehs.nih.gov/whatwestudy/niceatm/accept-methods/apps -
Speaker Biographies: Collaborative Workshop on Aquatic Models...
... His research involves the development of cell and zebrafish models to study the causes of Parkinson's disease and to develop novel therapies. Dr. Bronstein earned his bachelor's ...
Size: 1.8MB https://ntp.niehs.nih.gov/iccvam/meetings/aquatictox-2014/aquatictox-speakerbios-508.pdf -
Notices
... (both autologous and allogeneic cell therapies). (3) viral-based nucleic acid systems ... For many autoimmune diseases there are no FDA- approved therapies, underscoring that there ...
Size: 208KB https://ntp.niehs.nih.gov/sites/default/files/2025-07/FR-2025-12480.pdf -
RoC Profile: Nitrosourea Chemotherapeutic Agents; 15th RoC 2021
... use with other anti- cancer therapies in the treatment of preexisting cancer (IARC 1987). ... nonlymphocytic leukemia among 1,566 patients given other therapies (Boice et al. 1983). ...
Size: 215KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/nitrosoureachemotherapeuticagents.pdf -
RoC Profile: Norethisterone; 15th RoC 2021
... and dysmenorrhea, and in hormone replace- ment therapies (IARC 1979, MedlinePlus 2009b). ... Norethisterone acetate is also administered in several hormone replacement therapies ...
Size: 123KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/norethisterone.pdf -
RoC Profile: Progesterone; 15th RoC 2021
... or estrogen-progesterone combinations used as oral contraceptives or menopausal therapies. ... uterine bleeding and in combination hormone-replacement therapies (MedlinePlus 2009). ...
Size: 138KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/progesterone.pdf -
Nomination of BioSentinel Methods for Detection of Botulinum...
Pharmaceutical manufacturing of BoNT-based therapies and cosmetics accounts for an estimated 600,000 animal deaths per year (Adler, 2010). . Development of new BoNT-based therapies ...
Size: 1.7MB https://ntp.niehs.nih.gov/iccvam/methods/biologics/biosentinel/biosentinelcover-508.pdf -
Tissue Chips for Drug Screening Program (ICCVAM 2023 Public Forum...
risk assessment to accurately evaluate the efficacy, safety and toxicity of promising therapies https://ncats.nih.gov/tissuechip . Represents 10 Major Organ Systems . Circulatory . ...
Size: 4.9MB https://ntp.niehs.nih.gov/sites/default/files/2023-06/22_tagle_iccvamforum2023_508.pdf -
RoC Background Document: Cyclosporin A; Nov. 18-19, 1996
3.2.2 CsA, Possibly Other Immunosuppressive Therapies ...... 12 3.2.3 CsA in Combination with Other Immunosuppressive Therapies......
Size: 4.9MB https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/cyclosporin_a1_508.pdf
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