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How do we learn what disease biology is driven by environment and GxE?
... at scale will also allow us to better calibrate interindividual variability in exposures, and more rationally choose appropriate therapies. Most obvious deep drive traits... ...
Size: 782KB https://www.niehs.nih.gov/sites/default/files/2025-05/how-do-we-learn-what-disease-biology-is-driven-by-environment-and-gxe_ppt_long_508.pdf -
Myositis Disease Activity Assessment Tool - 2009
... other immunosuppressive agents, antimalarials, NSAIDs or symptomatic therapies are likely to be low.] CATEGORY D System previously affected but currently inactive ...
Size: 210KB https://www.niehs.nih.gov/sites/default/files/2025-05/scoring_of_myositis_disease_activity_assessment_tool_2009_pdfat_508.pdf -
Report to the National Advisory Environmental Health Sciences Council Director, NIEHS
... Increases to every Institute and Center to continue investments in innovative research that will advance fundamental knowledge and speed the development of new therapies, ...
Size: 299KB https://www.niehs.nih.gov/sites/default/files/about/boards/naehsc/agenda/sep2015/sept_2015_report_of_the_director_niehs_508.pdf -
FY 2010 NIEHS Director's Statement
... cellular models for ADHD and autism -- models that will help determine how neurotoxic substances may impact brain development and behavior, and may be useful in testing therapies. ...
Size: 808KB https://www.niehs.nih.gov/sites/default/files/about/congress/justification/2010/2010_directors_508.pdf -
Fiscal Year 2022 Congressional Justification
... Other projects are exploring therapies to block the virus from attaching to the cell and to disrupt the inflammation associated with severe COVID-19 lung infections. NIEHS is also ...
Size: 3.2MB https://www.niehs.nih.gov/sites/default/files/about/congress/justification/2022/2022_congressional_508.pdf -
John Bucher
... So you have two models that are developed at about the same time that are conceptually tied to the cancer process. They're advertised as being quick, cheap, using fewer animals and ...
Size: 75KB https://www.niehs.nih.gov/sites/default/files/about/history/anniversary/reflections/john_bucher_november_14_2003_508.pdf -
Kristine Witt Oral History Transcript
... But there were so few chemicals that were positive that it wasn't worth the effort of doing the test when you could get -- bacterial tests were so quick, relatively cheap and with ...
Size: 135KB https://www.niehs.nih.gov/sites/default/files/about/history/anniversary/reflections/kristine_witt_april_13_2004_508.pdf -
Genetic and Environmental Risk Factors for Myositis Phenotypes Across the Life Span
... Insights into biological pathways of disease . May suggest new therapies, and identify ... and rechallenge (recurrence after agent re-exposure), esp. for drugs, biologic therapies . ...
Size: 4.9MB https://www.niehs.nih.gov/sites/default/files/2025-05/eag-council-meeting_ppt_long_508.pdf -
NAEHSC Meeting Minutes June 2021
... markers and health outcomes. "The technology is here, and obviously needs much more development to make everything scalable and cheap enough," she added. Dr. Kavanagh asked Dr. ...
Size: 182KB https://www.niehs.nih.gov/sites/default/files/about/boards/naehsc/agenda/sep2021/june_2021_minutes_508.pdf -
Asthma and Its Environmental Triggers fact sheet
... observations suggest potential ways that therapies could help stop ozone-induced asthma. ... Asthma therapies A large-scale study that looks at the structure and function of proteins, ...
Size: 2.3MB https://www.niehs.nih.gov/sites/default/files/asthma-fact-sheet-print_508.pdf
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