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Handbook on Methods for Conducting Cancer Hazard Evaluations...
... Strauß A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U. 2020. Cancer stem cells-origins and biomarkers: Perspectives for RoC Handbook D-43 targeted personalized therapies. ...
Size: 5.2MB https://ntp.niehs.nih.gov/sites/default/files/2025-05/handbook_roc_508.pdf - 
    
ICCVAM Test Method Evaluation Report: In Vitro Cytotoxicity Test...
... The field ofuse.is directed to the development of therapies for remedying enzyme deficiencies in the treatment of Gaucher Disease. The prospective exclusive license will be ...
Size: 14.6MB https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/at-tmer-complete.pdf - 
    
ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity...
... The field of use is directed to the development of therapies for remedying enzyme deficiencies in the treatment of Gaucher Disease. The prospective exclusive license will be ...
Size: 61.6MB https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf - 
    
imacs_outcomes_repository_research_guidelines_pdf_format
Other applications of the data include comparing responses to therapies and developing predictors of response. The IMACS Outcomes Repository is open to IMACS members for research ...
Size: 38KB https://www.niehs.nih.gov/sites/default/files/2025-05/imacs_outcomes_repository_research_guidelines_pdfat_508.pdf - 
    
Genes, Environment, and Health Initiative: Exposure Biology Program - Executive Summary
This four-year effort will create a capacity for further research which will lead to better predictions of disease outcomes, more precise therapies for the treatment of many ...
Size: 116KB https://www.niehs.nih.gov/sites/default/files/about/assets/docs/genes_environment_and_health_initiative_exposure_biology_program_executive_summary_508.pdf - 
    
imacs_repository_data_use_agreement
The goals are to develop standardized, validated outcome measures for myositis therapeutic trials, compare responses to therapies, develop predictors of therapeutic response, and ...
Size: 77KB https://www.niehs.nih.gov/sites/default/files/research/resources/assets/docs/imacs_repository_data_use_agreement_508.pdf - 
    
NIEHS Translational Research Story Lupus: Uncovering Targets to Treat Pain and Chronic...
and pain, ultimately leading to therapies now advancing through clinical trials," ... sEH-related anti-inflammatory therapies to improve outcomes from SARS-CoV-2 ...
Size: 685KB https://www.niehs.nih.gov/sites/default/files/2025-08/Uncovering%20Targets%20to%20Treat%20Pain%20and%20Chronic%20Diseases%20Fact%20Sheet_print_508.pdf - 
    
Concept Clearance - CCRP Initiative: Chemical Threat Agent Inhalational Exposure...
and oversee a comprehensive biodefense program to discover therapies to address the WMD terrorist threats posed by infectious diseases, radiation, nuclear, and chemical exposure. ...
Size: 90KB https://www.niehs.nih.gov/sites/default/files/about/boards/naehsc/agenda/feb2022/concept_ccrp_initiative_508.pdf - 
    
Concept Clearance Statistical, Bioinformatics, and Analytical Methods for Detection...
The ultimate success of GWAS studies and other gene discovery techniques for contributing to targeted therapies, interventions, or preventive strategies for complex diseases will ...
Size: 56KB https://www.niehs.nih.gov/sites/default/files/about/boards/naehsc/agenda/sep2010/statistical_bioinformatics_and_analytical_methods_for_detection_of_g_x_e_interactions_in_complex_diseases_508.pdf - 
    
Proceedings from the Third National Institutes of Health International Congress on...
... Currently, there are limited noninvasive therapies for fibroids and no early intervention ... etiology and possible therapies for fibroids, although each model has its own limitations. ...
Size: 569KB https://www.niehs.nih.gov/research/atniehs/labs/assets/docs/e_j/human_reproduction_update_508.pdf 
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