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ICCVAM Biennial Progress Report 2018-2019 (text version)
... The goal of these models is to advance therapies for degenerative retinal diseases such as age-related macular degeneration, glaucoma, and diabetic retinopathy. In this phase of ...
Size: 1.0MB https://ntp.niehs.nih.gov/iccvam/docs/annrpt/iccvam-rpt-2018-2019.pdf -
ICCVAM Background Review Document: Validation Status of Five...
... such as cellular therapies, medical devices and pollution control in the work place. ... 50 years, it fails for important new therapies such as cellular products or ...
Size: 10.6MB https://ntp.niehs.nih.gov/iccvam/docs/pyrogen/brd/pyrobrd2008.pdf -
ICCVAM Test Method Evaluation Report: Five In Vitro Pyrogenicity...
... More work will have to be carried out to understand the types of materials that could be tested in these assays and how they would be handled (e.g., cell therapies and implants). ...
Size: 7.4MB https://ntp.niehs.nih.gov/iccvam/docs/pyrogen/tmer/pyrotmer2008.pdf -
Articles by Topic and Agency
... Acute Toxicity, Inhalation Toxicity NIEHS Safety testing strategy for cell-based human cancer therapies Preclinical safety assessment for CAR T cell-based therapies is necessary ...
https://ntp.niehs.nih.gov/iccvamreport/2023/tags -
Final RoC Background Document for Formaldehyde
... was estimated using in-depth interviews that probed subjects about duration and intensity of exposure from jobs held six months or more, relevant hobbies, and medical therapies. ...
Size: 5.8MB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2009/november/formaldehyde_bd_final.pdf -
TR-568: Photocarcinogenesis Studies of Retinoic Acid and Retinyl...
... Among the most-used therapies for prevention and reversal of photodamage to the skin are topical retinoids (Fisher et al., 1999). These include RA and its precur- sors (i.e., ...
Size: 11.9MB https://ntp.niehs.nih.gov/go/tr568 -
TR 577: Nondecolorized Whole Leaf Extract of Aloe Barbadensis...
... Assessment of patients' perceptions and beliefs regarding herbal therapies. Pharmacotherapy 20, 83-87. Koch, A. (1996). Metabolism of aloin - the influence of nutrition. J. Pharm. ...
Size: 9.6MB https://ntp.niehs.nih.gov/go/tr577 -
Monograph on Potential Human Reproductive and Developmental Effects...
... a comparison of the pregnancy outcome effects of medication with the effects of nonmedication therapies, e.g., cognitive behavioral or interpersonal therapies, in pregnant women. ...
Size: 2.4MB https://ntp.niehs.nih.gov/go/fluoxetine_monograph -
CERHR Monograph: Soy Infant Formula
... to other non-hormonal pharmacological therapies. 2.2.6 Bone Density Declines in ... hormone replacement therapies in affecting breast cancer mortality also is evident (483). ...
Size: 122.6MB https://ntp.niehs.nih.gov/go/soy_monograph -
Handbook on Methods for Conducting Cancer Hazard Evaluations...
... Strauß A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U. 2020. Cancer stem cells-origins and biomarkers: Perspectives for RoC Handbook D-43 targeted personalized therapies. ...
Size: 5.2MB https://ntp.niehs.nih.gov/sites/default/files/2025-05/handbook_roc_508.pdf
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