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Minutes: BSC RoC; Dec. 13-15, 2000
... He believed that the data on estrogen use alone in relation to endometrial cancer were very strong. He recognized that the combination therapies have a mediating effect but thought ...
Size: 205KB https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/minutes20001213.pdf -
TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage...
... This combined therapy (PUVA) is one of the few therapies that cause proliferation (melanogene- sis)and growth arrest (inhibition of cell growth) in the same tissue (basal layer of ...
Size: 7.8MB https://ntp.niehs.nih.gov/go/tr359 -
TR-367: Phenylbutazone (CASRN 50-33-9) in F344/N Rats and B6C3F1Mice...
... Several confounding factors, including addition- al drug therapies, reliance on patients' reporting of medication intake, dosage differences, and di- agnostic radiation exposure of ...
Size: 10.5MB https://ntp.niehs.nih.gov/go/tr367 -
TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344...
... Heptahydrate, NTP TR 471 has largely stopped because of associated toxicity (gastrointestinal upset, goiter, car- diomyopathies) and the development of less hazardous therapies. ...
Size: 13.1MB https://ntp.niehs.nih.gov/go/tr471 -
TR-485: Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology...
... The recommended dosages for treatment of anemias differ for each patient but are usually in the range of 1 to 5 mg/kg body weight per day, with minimum therapies lasting 3 to 6 ...
Size: 12.4MB https://ntp.niehs.nih.gov/go/tr485 -
TR-489: Magnetic Field Promotion (DMBA Initiation) in Sprague...
... in advanced cancers resistant to standard antitumor therapies (Lissoni et al., 1991). ... the pineal hormone melatonin in advanced cancer resistant to standard antitumor therapies. ...
Size: 9.4MB https://ntp.niehs.nih.gov/go/tr489 -
TR-522: Transplacental AZT (CASRN 30516-87-1) in Swiss (CD-1...
... The most effective recommended therapies (referred to as Highly Active Antiretroviral Therapies, HAART) consist of combinations of drugs. AZT is sup- plied as a single drug for ...
Size: 2.1MB https://ntp.niehs.nih.gov/go/tr522 -
TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered...
... to shift away from hormone-replacement therapies that can produce unwanted side effects. ... of plant-based therapies and menopausal symptoms: A systematic review and meta-analysis. ...
Size: 3.1MB https://ntp.niehs.nih.gov/go/tr603 -
OHAT Risk of Bias Rating Tool for Human and Animal Studies; January...
... For some health outcomes, consideration of additional therapies, including medications, may also be appropriate. By definition, confounders are specific for the outcome and the ...
Size: 441KB https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/pubs/riskofbiastool_508.pdf -
TOX-05: Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1...
... This practice has largely stopped because of associ- ated toxicity (gastrointestinal upset, goiter, car- diomyopathies) and the development of less haz- ardous therapies. It has ...
Size: 2.7MB https://ntp.niehs.nih.gov/sites/default/files/2023-08/tox05_508.pdf
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