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Your Environment. Your Health.

2020 Stories of Success

Ben Van Houten, Ph.D.
Exploring How Cells Find and Repair Damaged DNA

June 17, 2020

Ben Van Houten, Ph.D.

Ben Van Houten, Ph.D., uses innovative techniques to study how common forms of DNA damage are detected and repaired. Van Houten’s research is revealing how proteins find and repair damaged DNA sites known as DNA lesions.
Margaret Karagas, Ph.D.
Examining Health Impacts from Infancy to Adulthood

April 1, 2020

Margaret Karagas, Ph.D.

NIEHS grantee Margaret Karagas, Ph.D., studies how exposure to environmental chemicals affects our health throughout the life course.
Wen Xie, M.D., Ph.D.
Examining Xenobiotic Receptor-Mediated Gene Regulation in Metabolism and Disease

April 1, 2020

Wen Xie, M.D., Ph.D.

Wen Xie, M.D., Ph.D., studies how a cellular protein that detects environmental chemicals, called pregnane X receptors (PXR) also plays a role in normal functions and liver disease.
Matt Cave M.D.
Exploring the Role of Environmental Chemicals in Liver Disease

March 31, 2020

Matt Cave, M.D.

Matt Cave, M.D., explores how environmental chemicals and diet can interact and contribute to liver disease.
Gary Perdew, Ph.D.
Examining Links Between AHR, Microbiome, and Immune Functions

March 30, 2020

Gary Perdew, Ph.D.

Gary Perdew, Ph.D., studies how the aryl hydrocarbon receptor (AHR) pathway interacts with the microbiome, the immune system, and protective barriers in skin and the gut.
Brandon Pierce, Ph.D.
Uncovering Mechanisms of Arsenic Susceptibility in Bangladeshi Populations

March 26, 2020

Brandon Pierce, Ph.D.

Brandon Pierce, Ph.D., seeks to understand how genetic differences can make a person more or less susceptible to the health effects of arsenic exposure.
Martyn Smith, Ph.D.
Understanding and Predicting the Links Between Exposure and Disease

March 24, 2020

Martyn Smith, Ph.D.

Important discoveries by long-time NIEHS grantee Martyn Smith, Ph.D., shed light on how exposure to contaminants can harm health and improve assessment of the health risks of different chemicals. Since its inception in 1987, Smith has directed the Superfund Research Program (SRP) Center at the University of California, Berkeley (UC Berkeley).
Myron Goodman, Ph.D.
Characterizing an On-off Switch for DNA Mutations

March 24, 2020

Myron Goodman, Ph.D.

Myron Goodman, Ph.D., studies a highly unusual DNA polymerase in E. coli bacteria called pol V that can both repair DNA and cause mutations at high frequencies. Polymerases are enzymes that build chains of polymers such as nucleic acids, the building blocks of DNA and RNA.
Kim Tieu, Ph.D.
Studying the Puzzle Pieces that Contribute to Parkinson’s Disease Risk

March 19, 2020

Kim Tieu, Ph.D.

Kim Tieu, Ph.D., has long been fascinated by brain disorders, ever since learning about drugs that target the nervous system as a college student. He received an NIEHS Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) grant after discovering a new function of a long-studied protein involved in Parkinson’s disease (PD).
Walker, Graham, Ph.D. sitting in his office
Exploring How Cells Repair and Tolerate DNA Damage

February 28, 2020

Graham Walker, Ph.D.

Graham Walker, Ph.D., studies the processes cells use to repair and tolerate DNA damage from environmental pollutants. For more than 40 years, he has worked to understand how cells respond to DNA damage, and how these processes can introduce mutations that lead to cancer and other human diseases.
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