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Your Environment. Your Health.

Health Outcomes and Measures of the Environment (HOME) Study

Principal Investigator:
Lanphear, Bruce; Yolton, Kimberly; Braun, Joseph; Chen, Aimin
Institution:
Cincinnati Children’s Hospital Medical Center
Location:
Cincinnati, Ohio
Number of Participants:
401 Mothers and 410 children
Lifestage of Participants:
Prenatal, Infant (0-1 year), Youth (1-18 years)
Exposures:
Phenols (e.g., Bisphenol A (BPA) and Triclosan), Flame retardants, Perfluoroalkyl substances (PFASs), Phthalates, Environmental tobacco smoke, Polychlorinated biphenyls (PCBs), Lead, Mercury/Methylmercury, Pesticides, Built environment
Health Outcomes:
Attention deficit hyperactivity disorder (ADHD), Asthma, Infectious disease/infection, Neurobehavioral outcomes, Obesity, Thyroid function, Physical injury, Growth
Brief Description:
This is a birth cohort study in Cincinnati to evaluate the impact of low-level fetal and early childhood chemical exposures on health, developmental, and behavioral outcomes. The study recruited over 400 pregnant women between 2003 to 2006. Offspring have been followed to age 8 years, and new follow-up at age 12 years is ongoing for 410 live-born children, all are eligible for continued follow-up.

Related NIEHS-Funded Projects

Projects listed supported initial development of the epidemiological resource, added study participants, collected additional information or samples from study participants, and/or used samples or datasets derived from the resource.

Early Life Perfluoroalkyl Substance Exposure & Obesity: Mechanisms & Phenotyping

Grant Number:
Principal Investigator:
Braun, Joseph M
Institution:
Brown University
Most Recent Award Year:
2016
Additional Details

Endocrine Disrupting Chemicals, Thyroid Hormones, and Child Neurobehavior

Grant Number:
Principal Investigator:
Braun, Joseph M
Institution:
Brown University
Most Recent Award Year:
2015
Additional Details

Prenatal Sex Steroids, Bisphenol A, Phthalates, and Sexually Dimorphic Behaviors

Grant Number:
Principal Investigator:
Braun, Joseph M
Institution:
Harvard University
Most Recent Award Year:
2012
Additional Details

Longitudinal study of exposure to PBDEs and PFCs and child neurobehavior

Grant Number:
Principal Investigator:
Chen, Aimin (Contact); Lanphear, Bruce P; Yolton, Kimberly
Institution:
University of Cincinnati
Most Recent Award Year:
2011
Additional Details

Prenatal Low Level Tobacco & Phthalate Exposure & Childhood Respiratory Health

Grant Number:
Principal Investigator:
Spanier, Adam J
Institution:
Pennsylvania State University
Most Recent Award Year:
2008
Additional Details

Mechanisms of Pesticide-Induced Neurobehavioral Deficits: Relevance to ADHD

Grant Number:
Principal Investigator:
Richardson, Jason R
Institution:
RBHS-Robert Wood Johnson Medical School
Most Recent Award Year:
2007
Additional Details

Neurobehavioral Effects of Insecticides Exposure in Pregnancy and Early Childhood

Grant Number:
Principal Investigator:
Yolton, Kimberly
Institution:
Cincinnati Children's Hospital Medical Center
Most Recent Award Year:
2009
Additional Details

A Community-Based Trial to Prevent Lead Poisoning and Injuries

Grant Number:
Principal Investigator:
Lanphear, Bruce; Yolton, Kimberly
Institution:
Cincinnati Children's Hospital Medical Center
Most Recent Award Year:
2007
Additional Details

Study of Prevalent Neurotoxicants in Children

Grant Number:
Principal Investigator:
Lanphear, Bruce
Institution:
Cincinnati Children's Hospital Medical Center
Most Recent Award Year:
2001
Additional Details