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Your Environment. Your Health.

The New Hampshire Birth Cohort Study

Principal Investigator:
Karagas, Margaret
Institution:
Dartmouth College
Location:
New Hampshire; Vermont
Number of Participants:
1,500+ Mother-infant pairs
Lifestage of Participants:
Prenatal, Infant (0-1 year), Youth (1-18 years), Adulthood (18+ years)
Exposures:
Arsenic, Mercury/Methylmercury, Nutrition/Diet, Drinking water, Indoor air pollution
Health Outcomes:
Birthweight, Gestational age, Growth, Cardiovascular disease, Allergic response, Asthma, Immune function, Infection, Neurobehavioral outcomes, Neurodevelopmental outcomes
Brief Description:
This is a prospective pregnancy cohort study of mothers who use private wells for household water in New Hampshire designed to evaluate maternal/child health impacts of arsenic and other contaminants. The study has recruited over 1,500 mother-infant pairs (over 3,000 individuals) since 2009.

Related NIEHS-Funded Projects

Projects listed supported initial development of the epidemiological resource, added study participants, collected additional information or samples from study participants, and/or used samples or datasets derived from the resource.

Air Pollution Exposure During Pregnancy, Maternal Glycemia and Offspring Growth

Grant Number:
Principal Investigator:
Fleisch, Abby
Institution:
Children’s Hospital Corporation
Most Recent Award Year:
2015
Additional Details

Preclinical Indicators & Biomarkers of Cardiovascular Effects of Arsenic Exposure

Grant Number:
Principal Investigator:
Farzan, Shohreh F
Institution:
Dartmouth College/University of Southern California
Most Recent Award Year:
2014
Additional Details

Environment, Imprinting, and Neurodevelopment

Grant Number:
Principal Investigator:
Marsit, Carmen Joseph (Contact); Chen, Jia
Institution:
Dartmouth College
Most Recent Award Year:
2013
Additional Details

Project 1: Childhood Immune Function and Exposure

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (contact); Nadeau, Kari C (subcontract, Stanford University)
Institution:
Dartmouth College
Most Recent Award Year:
2013
Additional Details

Project 2: Water & Dietary Arsenic Exposure Related to Early Growth & Neurodevelopment

Grant Number:
Principal Investigator:
Cottingham, Kathryn Linn (contact); Korrick, Susan (subcontract, Harvard University)
Institution:
Dartmouth College
Most Recent Award Year:
2013
Additional Details

Project 3: Placental Biomarkers of Exposure and Outcome

Grant Number:
Principal Investigator:
Marsit, Carmen Joseph (contact); Robbins, David J (subcontract, University of Miami)
Institution:
Dartmouth College
Most Recent Award Year:
2013
Additional Details

Arsenic and T Cell Function: an Environment Maternal/Child Immunity Study

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Nadeau, Kari C (co-PI, Stanford University)
Institution:
Dartmouth College
Most Recent Award Year:
2012
Additional Details

Project 1: Arsenic and Maternal and Infant Immune Function

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Nadeau, Kari C (subcontract, Stanford University)
Institution:
Dartmouth College
Most Recent Award Year:
2010
Additional Details

Project 2: Food Borne Exposure to Arsenic During the First Years of Life

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Cottingham, Kathryn
Institution:
Dartmouth College
Most Recent Award Year:
2010
Additional Details

Project 3: An Integrated Geospatial & Epidemiological Study of Assoc.

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Shi, Xun
Institution:
Dartmouth College
Most Recent Award Year:
2010
Additional Details

Project 4: Determining How Arsenic Modulates Hedgehog Signaling During Development

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Robbins, David J (subcontract, University of Miami)
Institution:
Dartmouth College
Most Recent Award Year:
2010
Additional Details

Project 4: Epidemiology, Biomarkers and Exposure Assessment of Metals

Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Stanton, Bruce
Institution:
Dartmouth College
Most Recent Award Year:
2008
Additional Details
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