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Your Environment. Your Health.

The Children's Health Study (CHS)

Principal Investigator:
Gilliland, Frank
Institution:
University of Southern California
Location:
Southern California
Number of Participants:
>11,000 (Multiple waves of enrollment)
Lifestage of Participants:
Prenatal, Infant (0-1 year), Youth (1-18 years), Adulthood (18+ years), Transgenerational
Exposures:
Traffic-related air pollutants, Nitric oxide/Nitrogen dioxide (NO/NO2), Ozone, Polycyclic aromatic hydrocarbons (PAHs), Particulate matter, Diesel exhaust particles, Elemental carbon, Environmental tobacco smoke, Metals, Psychosocial stress
Health Outcomes:
Airway hyperreactivity, Allergic response, Asthma, Lung function, Coronary artery disease, Diabetes, Obesity/Body weight, Metabolic syndrome, Neurobehavioral outcomes, Neurodevelopmental outcomes, Mental health
Brief Description:
This is a prospective study examining the roles of the environment and genetic susceptibility in children's respiratory health in Southern California. The study has recruited over 11,000 school children living in southern California.

Related NIEHS-Funded Projects

Projects listed supported initial development of the epidemiological resource, added study participants, collected additional information or samples from study participants, and/or used samples or datasets derived from the resource.

Early-Life Exposure to Urban Air Pollution and Externalizing Behaviors in Youth

Grant Number:
Principal Investigator:
Younan, Diana B
Institution:
University of Southern California
Most Recent Award Year:
2015
Additional Details

Air pollution, immune modulation of adipose tissue and type-2 diabetes risk factors

Grant Number:
Principal Investigator:
Mcconnell, Rob S (Contact); Akbari, Omid
Institution:
University of Southern California
Most Recent Award Year:
2014
Additional Details

Near roadway air pollution and metabolic dysfunction among minority children and

Grant Number:
Principal Investigator:
Hsieh, Stephanie
Institution:
University of Southern California
Most Recent Award Year:
2014
Additional Details

Air pollution effects on asthma and lung function in Hispanic children

Grant Number:
Principal Investigator:
Gauderman, William James
Institution:
University of Southern California
Most Recent Award Year:
2013
Additional Details

Early detection of adverse respiratory effects from air pollution

Grant Number:
Principal Investigator:
Berhane, Kiros T; Gilliland, Frank D. (Contact)
Institution:
University of Southern California
Most Recent Award Year:
2013
Additional Details

Statistical Methods for Epigenetic Mediation of Exposure-response Relations

Grant Number:
Principal Investigator:
Thomas, Duncan C
Institution:
University of Southern California
Most Recent Award Year:
2012
Additional Details

Integrative Genetic Approaches to Gene-Air Pollution Interactions in Asthma

Grant Number:
Principal Investigator:
Akbari, Omid ; Allayee, Hooman ; Gilliland, Frank D. (Contact)
Institution:
University of Southern California
Most Recent Award Year:
2012
Additional Details

Mobile Sampling of Air Pollutants to Assess Exposure in a Large Cohort of Children

Grant Number:
Principal Investigator:
Fruin, Scott Anthony
Institution:
University of Southern California
Most Recent Award Year:
2010
Additional Details

Prenatal air pollution, DNA methylation and early signs of atherosclerosis

Grant Number:
Principal Investigator:
Breton, Carrie Van Doren
Institution:
University of Southern California
Most Recent Award Year:
2010
Additional Details

Childhood Asthma, Susceptibility and Biological Activity of Ambient Particles

Grant Number:
Principal Investigator:
Mcconnell, Rob S
Institution:
University of Southern California
Most Recent Award Year:
2008
Additional Details

Urban Air Pollution and Children's Respiratory Health

Grant Number:
Principal Investigator:
Mcconnell, Rob S
Institution:
University of Southern California
Most Recent Award Year:
2007
Additional Details

Genes, Air Pollution, Oxidant Stress, Inflammation and Children's Resp

Grant Number:
Principal Investigator:
Gilliland, Frank D
Institution:
University of Southern California
Most Recent Award Year:
2007
Additional Details
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