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Your Environment. Your Health.

Seychelles Child Development and Nutrition Study (SCDNS)

Principal Investigator:
Davidson, Philip
Institution:
University of Rochester
Location:
The Seychelles
Number of Participants:
4,000+
Lifestage of Participants:
Prenatal, Infant (0-1 year), Youth (1-18 years), Adulthood (18+ years)
Exposures:
Mercury/Methylmercury, Nutrition/Diet, Long chain polyunsaturated fatty acids (PUFA)
Health Outcomes:
Cardiovascular outcomes, Neurobehavioral outcomes, Neurodevelopmental outcomes
Brief Description:
This study, which began in the mid-1980s, includes several large cohorts of children whose mothers consumed fish frequently during their pregnancy. The study objective is to determine if prenatal methylmercury exposure from fish consumption has adverse effects on the children’s neurodevelopment as well as to document child development in the Seychelles. The Main cohort was recruited in 1989 and is comprised of 779 children. A subsequent Nutrition cohort (NC1) of 300 mothers was enrolled in 2001 during their first trimester of pregnancy. Most recently, a second Nutrition cohort (NC2) of 1,535 mother-child pairs was enrolled between 2008 and 2011.

Related NIEHS-Funded Projects

Projects listed supported initial development of the epidemiological resource, added study participants, collected additional information or samples from study participants, and/or used samples or datasets derived from the resource.

Factors Modifying the Toxicity of Methylmercury in a Fish-Eating Population

Grant Number:
Principal Investigator:
Davidson, Philip W
Institution:
University of Rochester
Most Recent Award Year:
2015
Additional Details

Susceptibility to methylmercury toxicity: A role for cytochrome p450 enzymes

Grant Number:
Principal Investigator:
Rand, Matthew D
Institution:
University of Rochester
Most Recent Award Year:
2012
Additional Details

Methyl Mercury Effect on Adolescent Development Renewal

Grant Number:
Principal Investigator:
Davidson, Philip W
Institution:
University of Rochester
Most Recent Award Year:
2010
Additional Details

Mercury Vapor from Amalgam and Methylmercury Co-Exposure on Neurodevelopment

Grant Number:
Principal Investigator:
Watson, Gene E
Institution:
University of Rochester
Most Recent Award Year:
2007
Additional Details
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