Skip Navigation

Your Environment. Your Health.

Small Business Innovative Research Grants (R34/R44)

Hazardous Substances Detection and Remediation Program

The NIEHS Superfund Research Program (SRP) "Hazardous Substances Detection and Remediation Program" supports Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44) to foster the commercialization of technologies, products, and devices for detection and remediation of hazardous substances in the environment. The SRP is specifically interested in proposals applying new engineering, bioengineering, and biotechnology approaches to develop novel strategies to characterize, monitor, and remediate hazardous substances at contaminated sites.

Man testing hazardous materials

Topics of interest include, but are not limited to:

Monitoring, Detection, and Site Characterization

  • Real-time, on-site monitoring: soil, surface water, groundwater, subsurface, sediments, air (such as volatile releases from sites), etc.
  • Nanotechnology-based sensors and probes, biosensors, and miniaturized analytical probes
  • Non-targeted or multi-analyte field sampling tools or kits
  • Products that allow for rapid sample clean-up/preparation for analysis of environmental samples
  • Devices to detect chemical mixtures in environmental media
  • Self-contained miniaturized toxicity-screening kits for detecting contamination hotspots
  • Assays or devices to determine the extent to which a contaminant is bioavailable
  • High throughput assays or toxicity screening products for use in ecological risk assessments
Examples of specific environmental monitoring, detection, and site characterization needs:
  • Devices to detect and measure vapor intrusion or to detect non-aqueous phase liquids (NAPLs) and dense non-aqueous phase liquids (DNAPLs) in the subsurface
  • Site characterization techniques and strategies for complex geology (fractured, karst and heterogeneous layered deposits)
  • Short-duration tests or methods to improve identification of reasonable worst case vapor intrusion condition in a building
  • Technologies for rapid extraction or processing of soil for incremental sampling methodologies (ISM)
  • Technologies for automated fiber counting for asbestos samples
  • Novel technologies for in situ remediation of contaminated sediments, soils, and groundwater
  • Technologies to remediate chemical mixtures in environmental media
  • Portable adsorption systems for removing chlorinated VOCs from indoor air to achieve risk-based indoor air standards
  • Nano-enabled structures, electrochemical methods, photocatalytic processes, thermal treatments, or filtration-based methods of remediation.
  • Bioremediation and phytoremediation technologies including development and culturing/propagation of plants, bacterial strains, or fungal species optimized for bioremediation.
  • New strategies for delivery of reagents for groundwater remediation: in situ chemical oxidation ISCO), zero valent iron (ZVI), and hydraulic fracturing (note: this excludes gas exploration)
  • New strategies for delivery of reagents for recovery/extraction of contaminants in groundwater
Information Technology to Support Monitoring and Remediation
  • Computational, geographical information system-based, or modeling products for predicting fate and transport of contaminants, rates of remediation, or for identifying contamination sources
  • Miniaturized data analysis tools

SRP encourages applicants to develop green / sustainable detection technologies and remediation approaches that improve energy efficiency and reduce waste generation. Proposals must demonstrate that the proposed detection and remediation technologies are relevant to Superfund.

Please see the NIH SBIR/STTR webpage for application information or visit the NIEHS SBIR/STTR webpage for other SBIR/STTR opportunities within NIEHS.

Annual Application Receipt Dates are January 5, April 5, and September 5, 2017; however, applicants are encouraged to submit their applications several days in advance of the deadline.

Please see SRP’s Currently Funded SBIR/STTR Programs webpage to learn about the research we support.


On October 3, 2016, the SRP, the U.S. Environmental Protection Agency, the National Science Foundation, and the U.S. Department of Agriculture presented a webinar titled, "U.S. Small Business Funding Opportunities (SBIR/STTR) for Environmental Technologies." This webinar was designed to help small businesses and academic researchers better understand (1) the different agencies that fund environmental technologies and (2) the fundamental goals of the SBIR and STTR programs. You can view an archive of the webinar on EPA's CLU-IN Training & Events Web page.
The NIEHS contact person is:
Heather Henry, Ph.D.
Health Scientist Administrator
Superfund Research Program
Tel (919) 541-5330

Share This Page:

Page Options:

Request Translation Services