Translation regulation of gene expression in toxic dinoflagellates
Rosemary Jagus, Ph.D.
NIEHS Grant: R01ES021949
Investigators at the University of Maryland Center for Environmental Science are studying the mechanisms by which dinoflagellates regulate their growth and respond to the environment. A number of dinoflagellate species produce strong neurotoxins when they bloom, and studies have implicated mRNA recruitment as a major site of regulation of gene expression for these organisms. The researchers are working to better understand the key players in translational regulation for the dinoflagellates Karlodinium veneficum and Karenia brevis. These studies will provide critical insight into mechanisms relevant to dinoflagellate growth, toxicity, and the regulation of harmful algal blooms, with a long term goal of providing avenues for intervention.