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Erythroleukemia is a spontaneous hematopoietic neoplasm of Tg.AC mice characterized by marked hepatomegaly. The affected liver is infiltrated by metarubricytes and less differentiated erythroid precursors.

Low magnification of erythroleukemic infiltrates in the liver.

A higher magnification of hepatic erythroleukemia.

Examples of erythroleukemia in a Tg.AC mouse.