The zipped archive hybrid_design.zip provides information for fitting log-linear models and carrying out statistical tests for a design that includes affected individuals and their parents and also a population-based sample of parents of unaffected individuals, as described in the paper "A hybrid design for studying genetic influences on diseases with onset early in life," Weinberg, C.R. and Umbach, D.M. Am. J. Hum. Gen., 2005, 77:627-636.

The terms and conditions for the use of the models are as outlined below. These terms are subject to change without notice and at the discretion of the developer. If you accept these terms and conditions then please download the software by clicking on the provided link at the end.

• The code is provided "as is" and does not come with any warranties. In no circumstance will the developer, the programmers, the National Institute of Environmental Health Sciences, NIH, HHS or any of our associates, be liable for any direct or indirect damages.
• You should give proper credit to the developer by citing the above publication.
• If you agree to the above then click Hybrid Design (29KB).

Contact

Clarice R. Weinberg, Ph.D.
Principal Investigator

Tel 984-287-3697
[email protected]

David M. Umbach, Ph.D.
Staff Scientist

Tel 984-287-3703
[email protected]