Recently Published Research

Impact of Lowering the US Maximum Contaminant Level on Arsenic Exposure: Differences by Race, Region, and Water Arsenic in NHANES 2003-2014 [Abstract Impact of Lowering the US Maximum Contaminant Level on Arsenic Exposure: Differences by Race, Region, and Water Arsenic in NHANES 2003-2014] [Synopsis Impact of Lowering the US Maximum Contaminant Level on Arsenic Exposure: Differences by Race, Region, and Water Arsenic in NHANES 2003-2014] Spaur M, Bostick BC, Chillrud SN, Factor-Litvak P, Navas-Acien A, Nigra AE. September 2023

Exposure to Volatile Hydrocarbons and Neurologic Function Among Oil Spill Workers up to 6 Years After the Deepwater Horizon Disaster [Abstract Exposure to Volatile Hydrocarbons and Neurologic Function Among Oil Spill Workers up to 6 Years After the Deepwater Horizon Disaster] [Synopsis Exposure to Volatile Hydrocarbons and Neurologic Function Among Oil Spill Workers up to 6 Years After the Deepwater Horizon Disaster] Chen D, Werder EJ, Stewart PA, Stenzel MR, Gerr FE, Lawrence KG, Groth CP, Huynh TB, Ramachandran G, Banerjee S, Jackson Ii WB, Christenbury K, Kwok RK, Sandler DP, Engel LS. August 2023

Indoor Wood-burning From Stoves and Fireplaces and Incident Lung Cancer Among Sister Study Participants [Abstract Indoor Wood-burning From Stoves and Fireplaces and Incident Lung Cancer Among Sister Study Participants] [Synopsis Indoor Wood-burning From Stoves and Fireplaces and Incident Lung Cancer Among Sister Study Participants] Mehta SS, Elizabeth Hodgson M, Lunn RM, Ashley CE, Arroyave WD, Sandler DP, White AJ. August 2023

Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells [Abstract Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells] [Synopsis Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells] Bellamri M, Brandt K, Cammerrer K, Syeda T, Turesky RJ, Cannon JR. August 2023

Changes in Methylation-based Aging in Women Who Do and Do Not Develop Breast Cancer [Abstract Changes in Methylation-based Aging in Women Who Do and Do Not Develop Breast Cancer] [Synopsis Changes in Methylation-based Aging in Women Who Do and Do Not Develop Breast Cancer] Kresovich JK, O'Brien KM, Xu Z, Weinberg CR, Sandler DP, Taylor JA. July 2023

Competitive Fluorescent Immunosensor Based on Catalytic Hairpin Self-Assembly for Multiresidue Detection of Organophosphate Pesticides in Agricultural Products [Abstract Competitive Fluorescent Immunosensor Based on Catalytic Hairpin Self-Assembly for Multiresidue Detection of Organophosphate Pesticides in Agricultural Products] [Synopsis Competitive Fluorescent Immunosensor Based on Catalytic Hairpin Self-Assembly for Multiresidue Detection of Organophosphate Pesticides in Agricultural Products] Wang Y, Abd El-Aty AM, Wang S, Cui X, Zhao J, Lei X, Xu L, She Y, Jin F, Eun JB, Shim JH, Wang J, Jin M, Hammock BD. July 2023

CYP Eicosanoid Pathway Mediates Colon Cancer-promoting Effects of Dietary Linoleic Acid [Abstract CYP Eicosanoid Pathway Mediates Colon Cancer-promoting Effects of Dietary Linoleic Acid] [Synopsis CYP Eicosanoid Pathway Mediates Colon Cancer-promoting Effects of Dietary Linoleic Acid] Zhang J, Yang J, Duval C, Edin ML, Williams A, Lei L, Tu M, Pourmand E, Song R, Graves JP, DeGraff LM, Wong JJ, Wang Y, Sun Q, Sanidad KZ, Wong S, Han Y, Zhang Z, Lee KSS, Park Y, Xiao H, Liu Z, Decker EA, Cui W, Zeldin DC, Zhang G. July 2023

Early Pregnancy Phthalates and Replacements in Relation to Fetal Growth: The Human Placenta and Phthalates Study [Abstract Early Pregnancy Phthalates and Replacements in Relation to Fetal Growth: The Human Placenta and Phthalates Study] [Synopsis Early Pregnancy Phthalates and Replacements in Relation to Fetal Growth: The Human Placenta and Phthalates Study] Stevens DR, Rosen EM, Van Wickle K, McNell EE, Bommarito PA, Calafat AM, Botelho JC, Sinkovskaya E, Przybylska A, Saade G, Abuhamad A, Ferguson KK. July 2023

Effects of Ambient Fine Particulates, Nitrogen Dioxide, and Ozone on Maturation of Functional Brain Networks Across Early Adolescence [Abstract Effects of Ambient Fine Particulates, Nitrogen Dioxide, and Ozone on Maturation of Functional Brain Networks Across Early Adolescence] [Synopsis Effects of Ambient Fine Particulates, Nitrogen Dioxide, and Ozone on Maturation of Functional Brain Networks Across Early Adolescence] Cotter DL, Campbell CE, Sukumaran K, McConnell R, Berhane K, Schwartz J, Hackman DA, Ahmadi H, Chen JC, Herting MM. July 2023

Evaluation of Immunotoxicity of Sodium Metavanadate Following Drinking Water Exposure in Female B6C3F1/N Mice in a 28-day Study. [Abstract Evaluation of Immunotoxicity of Sodium Metavanadate Following Drinking Water Exposure in Female B6C3F1/N Mice in a 28-day Study.] [Synopsis Evaluation of Immunotoxicity of Sodium Metavanadate Following Drinking Water Exposure in Female B6C3F1/N Mice in a 28-day Study.] Frawley R, Johnson VJ, Burleson GR, Shockley KR, Cesta MF, Travlos G, Cora M, Roberts G, Germolec D. July 2023

Glycidamide-induced Hypermutation in Yeast Single-stranded DNA Reveals a Ubiquitous Clock-like Mutational Motif in Humans [Abstract Glycidamide-induced Hypermutation in Yeast Single-stranded DNA Reveals a Ubiquitous Clock-like Mutational Motif in Humans] [Synopsis Glycidamide-induced Hypermutation in Yeast Single-stranded DNA Reveals a Ubiquitous Clock-like Mutational Motif in Humans] Hudson KM, Klimczak LJ, Sterling JF, Burkholder AB, Kazanov MD, Saini N, Mieczkowski PA, Gordenin DA. July 2023

Prenatal Benzene Exposure in Mice Alters Offspring Hypothalamic Development Predisposing to Metabolic Disease in Later Life [Abstract Prenatal Benzene Exposure in Mice Alters Offspring Hypothalamic Development Predisposing to Metabolic Disease in Later Life] [Synopsis Prenatal Benzene Exposure in Mice Alters Offspring Hypothalamic Development Predisposing to Metabolic Disease in Later Life] Koshko L, Scofield S, Debarba L, Stilgenbauer L, Fakhoury P, Jayarathne H, Perez-Mojica JE, Griggs E, Lempradl A, Sadagurski M. July 2023

The Translational Repressor Glorund Uses Interchangeable RNA Recognition Domains to Recognize Drosophila Nanos [Abstract The Translational Repressor Glorund Uses Interchangeable RNA Recognition Domains to Recognize Drosophila Nanos] [Synopsis The Translational Repressor Glorund Uses Interchangeable RNA Recognition Domains to Recognize Drosophila Nanos] Warden MS, DeRose EF, Tamayo JV, Mueller GA, Gavis ER, Hall TMT. July 2023

Algae Impacted Drinking Water: Does Switching to Chloramination Produce Safer Drinking Water? [Abstract Algae Impacted Drinking Water: Does Switching to Chloramination Produce Safer Drinking Water?] [Synopsis Algae Impacted Drinking Water: Does Switching to Chloramination Produce Safer Drinking Water?] Aziz MT, Granger CO, Ferry JL, Richardson SD. June 2023

Effects of Cyanobacterial Harmful Algal Bloom Toxin Microcystin-LR on Gonadotropin-dependent Ovarian Follicle Maturation and Ovulation in Mice [Abstract Effects of Cyanobacterial Harmful Algal Bloom Toxin Microcystin-LR on Gonadotropin-dependent Ovarian Follicle Maturation and Ovulation in Mice] [Synopsis Effects of Cyanobacterial Harmful Algal Bloom Toxin Microcystin-LR on Gonadotropin-dependent Ovarian Follicle Maturation and Ovulation in Mice] Wang Y, Pattarawat P, Zhang J, Kim E, Zhang D, Fang M, Jannaman EA, Yuan Y, Chatterjee S, Kim JJ, Scott GI, Zhang Q, Xiao S. June 2023

Financial Hardship, Sleep Disturbances, and Their Relationship Among Men and Women in the United States During the COVID-19 Pandemic [Abstract Financial Hardship, Sleep Disturbances, and Their Relationship Among Men and Women in the United States During the COVID-19 Pandemic] [Synopsis Financial Hardship, Sleep Disturbances, and Their Relationship Among Men and Women in the United States During the COVID-19 Pandemic] Gaston SA, Strassle PD, Alhasan DM, Pérez-Stable EJ, Nápoles AM, Jackson CL. June 2023

Glucocorticoids Regulate Thrombopoiesis by Remodeling the Megakaryocyte Transcriptome [Abstract Glucocorticoids Regulate Thrombopoiesis by Remodeling the Megakaryocyte Transcriptome] [Synopsis Glucocorticoids Regulate Thrombopoiesis by Remodeling the Megakaryocyte Transcriptome] Grodzielski M, Cidlowski JA. June 2023

Methylation-Based Biological Age and Hypertension Prevalence and Incidence [Abstract Methylation-Based Biological Age and Hypertension Prevalence and Incidence] [Synopsis Methylation-Based Biological Age and Hypertension Prevalence and Incidence] Kresovich JK, Sandler DP, Taylor JA. June 2023

Outdoor Air Pollution and Histologic Composition of Normal Breast Tissue [Abstract Outdoor Air Pollution and Histologic Composition of Normal Breast Tissue] [Synopsis Outdoor Air Pollution and Histologic Composition of Normal Breast Tissue] Ish JL, Abubakar M, Fan S, Jones RR, Niehoff NM, Henry JE, Gierach GL, White AJ. June 2023

Structural Basis for Pre-tRNA Recognition and Processing by the Human tRNA Splicing Endonuclease Complex [Abstract Structural Basis for Pre-tRNA Recognition and Processing by the Human tRNA Splicing Endonuclease Complex] [Synopsis Structural Basis for Pre-tRNA Recognition and Processing by the Human tRNA Splicing Endonuclease Complex] Hayne CK, Butay KJU, Stewart ZD, Krahn JM, Perera L, Williams JG, Petrovitch RM, Deterding LJ, Matera AG, Borgnia MJ, Stanley RE. June 2023

Weight Loss Relapse Associated With Exposure to Perfluorinated Alkylate Substances [Abstract Weight Loss Relapse Associated With Exposure to Perfluorinated Alkylate Substances] [Synopsis Weight Loss Relapse Associated With Exposure to Perfluorinated Alkylate Substances] Grandjean P, Meddis A, Nielsen F, Sjödin A, Hjorth MF, Astrup A, Budtz-Jørgensen E. June 2023

A Multi-omic Approach Identifies an Autism Spectrum Disorder (ASD) Regulatory Complex of Functional Epimutations in Placentas From Children Born Preterm [Abstract A Multi-omic Approach Identifies an Autism Spectrum Disorder (ASD) Regulatory Complex of Functional Epimutations in Placentas From Children Born Preterm] [Synopsis A Multi-omic Approach Identifies an Autism Spectrum Disorder (ASD) Regulatory Complex of Functional Epimutations in Placentas From Children Born Preterm] Freedman AN, Clark J, Eaves LA, Roell K, Oran A, Koval L, Rager J, Santos HP Jr, Kuban K, Joseph RM, Frazier J, Marsit CJ, Burt AA, O'Shea TM, Fry RC. May 2023

Microbial Modulation Via Cross-fostering Prevents the Effects of Pervasive Environmental Stressors on Microglia and Social Behavior, but Not the Dopamine System [Abstract Microbial Modulation Via Cross-fostering Prevents the Effects of Pervasive Environmental Stressors on Microglia and Social Behavior, but Not the Dopamine System] [Synopsis Microbial Modulation Via Cross-fostering Prevents the Effects of Pervasive Environmental Stressors on Microglia and Social Behavior, but Not the Dopamine System] Smith CJ, Rendina DN, Kingsbury MA, Malacon KE, Nguyen DM, Tran JJ, Devlin BA, Raju RM, Clark MJ, Burgett L, Zhang JH, Cetinbas M, Sadreyev RI, Chen K, Iyer MS, Bilbo SD. May 2023

Newborn Metabolomic Signatures of Maternal Per- and Polyfluoroalkyl Substance Exposure and Reduced Length of Gestation [Abstract Newborn Metabolomic Signatures of Maternal Per- and Polyfluoroalkyl Substance Exposure and Reduced Length of Gestation] [Synopsis Newborn Metabolomic Signatures of Maternal Per- and Polyfluoroalkyl Substance Exposure and Reduced Length of Gestation] Taibl KR, Dunlop AL, Barr DB, Li YY, Eick SM, Kannan K, Ryan PB, Schroder M, Rushing B, Fennell T, Chang CJ, Tan Y, Marsit CJ, Jones DP, Liang D. May 2023

Perceived Neighborhood Social Cohesion and Type 2 Diabetes Mellitus by Age, Sex/Gender, and Race/Ethnicity in the United States [Abstract Perceived Neighborhood Social Cohesion and Type 2 Diabetes Mellitus by Age, Sex/Gender, and Race/Ethnicity in the United States] [Synopsis Perceived Neighborhood Social Cohesion and Type 2 Diabetes Mellitus by Age, Sex/Gender, and Race/Ethnicity in the United States] Williams PC, Alhasan DM, Gaston SA, Henderson KL, Braxton Jackson W 2nd, Jackson CL. May 2023

Photoaging of Polystyrene Microspheres Causes Oxidative Alterations to Surface Physicochemistry and Enhances Airway Epithelial Toxicity [Abstract Photoaging of Polystyrene Microspheres Causes Oxidative Alterations to Surface Physicochemistry and Enhances Airway Epithelial Toxicity] [Synopsis Photoaging of Polystyrene Microspheres Causes Oxidative Alterations to Surface Physicochemistry and Enhances Airway Epithelial Toxicity] El Hayek E, Castillo E, In JG, Garcia M, Cerrato J, Brearley A, Gonzalez-Estrella J, Herbert G, Bleske B, Benavidez A, Hsiao H, Yin L, Campen MJ, Yu X. May 2023

Shared and Distinctive Transcriptomic and Proteomic Pathways in Adult and Juvenile Dermatomyositis [Abstract Shared and Distinctive Transcriptomic and Proteomic Pathways in Adult and Juvenile Dermatomyositis] [Synopsis Shared and Distinctive Transcriptomic and Proteomic Pathways in Adult and Juvenile Dermatomyositis] Ward J, Ambatipudi M, O'Hanlon TP, Smith MA, de Los Reyes M, Schiffenbauer A, Rahman S, Zerrouki K, Miller FW, Sanjuan MA, Li JL, Casey KA, Rider LG. May 2023

Air Pollution and Mortality at the Intersection of Race and Social Class [Abstract Air Pollution and Mortality at the Intersection of Race and Social Class] [Synopsis Air Pollution and Mortality at the Intersection of Race and Social Class] Josey KP, Delaney SW, Wu X, Nethery RC, DeSouza P, Braun D, Dominici F. April 2023

Changes in Metabolic Landscapes Shape Divergent but Distinct Mutational Signatures and Cytotoxic Consequences of Redox Stress [Abstract Changes in Metabolic Landscapes Shape Divergent but Distinct Mutational Signatures and Cytotoxic Consequences of Redox Stress] [Synopsis Changes in Metabolic Landscapes Shape Divergent but Distinct Mutational Signatures and Cytotoxic Consequences of Redox Stress] Degtyareva NP, Placentra VC, Gabel SA, Klimczak LJ, Gordenin DA, Wagner BA, Buettner GR, Mueller GA, Smirnova TI, Doetsch PW. April 2023

Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice [Abstract Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice] [Synopsis Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice] Ton TT, Hong HL, Kovi RC, Shockley KR, Peddada SD, Gerrish KE, Janardhan KS, Flake G, Stout MD, Sills RC, Pandiri AR. April 2023

Development of Novel Fluor Mop Materials for Remediation of Perfluoroalkyl Substances (PFAS) From Groundwater [Abstract Development of Novel Fluor Mop Materials for Remediation of Perfluoroalkyl Substances (PFAS) From Groundwater] [Synopsis Development of Novel Fluor Mop Materials for Remediation of Perfluoroalkyl Substances (PFAS) From Groundwater] Singh A, Lynch R, Solomon J, Weaver JD, May AR. April 2023

Disruption of Ephx2 in Cardiomyocytes but Not Endothelial Cells Improves Functional Recovery After Ischemia-reperfusion in Isolated Mouse Hearts [Abstract Disruption of Ephx2 in Cardiomyocytes but Not Endothelial Cells Improves Functional Recovery After Ischemia-reperfusion in Isolated Mouse Hearts] [Synopsis Disruption of Ephx2 in Cardiomyocytes but Not Endothelial Cells Improves Functional Recovery After Ischemia-reperfusion in Isolated Mouse Hearts] Edin ML, Gruzdev A, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Fleming I, Zeldin DC. April 2023

Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT): Developing a Data Analysis Pipeline for the Assessment of Developmental Toxicity With an Interlaboratory Study [Abstract Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT): Developing a Data Analysis Pipeline for the Assessment of Developmental Toxicity With an Interlaboratory Study] [Synopsis Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT): Developing a Data Analysis Pipeline for the Assessment of Developmental Toxicity With an Interlaboratory Study] Hsieh JH, Nolte S, Hamm JT, Wang Z, Roberts GK, Schmitt CP, Ryan KR. April 2023

Temperature and Mental Health-related Emergency Department and Hospital Encounters Among Children, Adolescents and Young Adults. [Abstract Temperature and Mental Health-related Emergency Department and Hospital Encounters Among Children, Adolescents and Young Adults.] [Synopsis Temperature and Mental Health-related Emergency Department and Hospital Encounters Among Children, Adolescents and Young Adults.] Niu L, Girma B, Liu B, Schinasi LH, Clougherty JE, Sheffield P. April 2023

Temporal Trends and Predictors of Phthalate, Phthalate Replacement, and Phenol Biomarkers in the LIFECODES Fetal Growth Study [Abstract Temporal Trends and Predictors of Phthalate, Phthalate Replacement, and Phenol Biomarkers in the LIFECODES Fetal Growth Study] [Synopsis Temporal Trends and Predictors of Phthalate, Phthalate Replacement, and Phenol Biomarkers in the LIFECODES Fetal Growth Study] Bommarito PA, Stevens DR, Welch BM, Weller D, Meeker JD, Cantonwine DE, McElrath TF, Ferguson KK. April 2023

Association Between Urban Green Space and Postpartum Depression, and the Role of Physical Activity: A Retrospective Cohort Study in Southern California [Abstract Association Between Urban Green Space and Postpartum Depression, and the Role of Physical Activity: A Retrospective Cohort Study in Southern California] [Synopsis Association Between Urban Green Space and Postpartum Depression, and the Role of Physical Activity: A Retrospective Cohort Study in Southern California] Sun Y, Molitor J, Benmarhnia T, Avila C, Chiu V, Slezak J, Sacks DA, Chen JC, Getahun D, Wu J. March 2023

Early Life Anti-müllerian Hormone Trajectories in Infant Girls [Abstract Early Life Anti-müllerian Hormone Trajectories in Infant Girls] [Synopsis Early Life Anti-müllerian Hormone Trajectories in Infant Girls] Chin HB, Krall JR, Goldberg M, Stanczyk FZ, Darge K, Stallings VA, Rogan WJ, Umbach DM, Baird DD. March 2023

Evaluation of the Herbicide Glyphosate, (Aminomethyl)Phosphonic Acid, and Glyphosate-based Formulations for Genotoxic Activity Using in Vitro Assays [Abstract Evaluation of the Herbicide Glyphosate, (Aminomethyl)Phosphonic Acid, and Glyphosate-based Formulations for Genotoxic Activity Using in Vitro Assays] [Synopsis Evaluation of the Herbicide Glyphosate, (Aminomethyl)Phosphonic Acid, and Glyphosate-based Formulations for Genotoxic Activity Using in Vitro Assays] Smith-Roe SL, Swartz CD, Rashid A, Christy NC, Sly JE, Chang X, Sipes NS, Shockley KR, Harris SF, McBride SJ, Larson GJ, Collins BJ, Mutlu E, Witt KL. March 2023

Structural and Ligand Binding Analysis of the Pet Allergens Can f 1 and Fel d 7 [Abstract Structural and Ligand Binding Analysis of the Pet Allergens Can f 1 and Fel d 7] [Synopsis Structural and Ligand Binding Analysis of the Pet Allergens Can f 1 and Fel d 7] Min J, Foo ACY, Gabel SA, Perera L, DeRose EF, Pomés A, Pedersen LC, Mueller GA. March 2023

Whole Exome and Transcript Profiling of Liver Following Aflatoxin B1 Exposure in Rats [Abstract Whole Exome and Transcript Profiling of Liver Following Aflatoxin B1 Exposure in Rats] [Synopsis Whole Exome and Transcript Profiling of Liver Following Aflatoxin B1 Exposure in Rats] Foley JF, Elgart B, Phadke D, Mav D, Tripodi I, Clausen N, Weick M, Gladwell W, Gerrish K, Shah R, Merrick BA. March 2023

25-hydroxycholesterol Exacerbates Vascular Leak During Acute Lung Injury [Abstract 25-hydroxycholesterol Exacerbates Vascular Leak During Acute Lung Injury] [Synopsis 25-hydroxycholesterol Exacerbates Vascular Leak During Acute Lung Injury] Madenspacher JH, Morrell ED, McDonald JG, Thompson BM, Li Y, Birukov KG, Birukova AA, Stapleton RD, Alejo A, Karmaus PW, Meacham JM, Rai P, Mikacenic C, Wurfel MM, Fessler MB. February 2023

Air Pollution and Decreased Bone Mineral Density Among Women's Health Initiative Participants [Abstract Air Pollution and Decreased Bone Mineral Density Among Women's Health Initiative Participants] [Synopsis Air Pollution and Decreased Bone Mineral Density Among Women's Health Initiative Participants] Prada D, Crandall CJ, Kupsco A, Kioumourtzoglou MA, Stewart JD, Liao D, Yanosky JD, Ramirez A, Wactawski-Wende J, Shen Y, Miller G, Ionita-Laza I, Whitsel EA, Baccarelli AA. February 2023

Detection of SARS-CoV-2 RNA in Wastewater and Comparison to COVID-19 Cases in Two Sewersheds, North Carolina, USA [Abstract Detection of SARS-CoV-2 RNA in Wastewater and Comparison to COVID-19 Cases in Two Sewersheds, North Carolina, USA] [Synopsis Detection of SARS-CoV-2 RNA in Wastewater and Comparison to COVID-19 Cases in Two Sewersheds, North Carolina, USA] Grube AM, Coleman CK, LaMontagne CD, Miller ME, Kothegal NP, Holcomb DA, Blackwood AD, Clerkin TJ, Serre ML, Engel LS, Guidry VT, Noble RT, Stewart JR. February 2023

Developmental Exposure to Domoic Acid Targets Reticulospinal Neurons and Leads to Aberrant Myelination in the Spinal Cord [Abstract Developmental Exposure to Domoic Acid Targets Reticulospinal Neurons and Leads to Aberrant Myelination in the Spinal Cord] [Synopsis Developmental Exposure to Domoic Acid Targets Reticulospinal Neurons and Leads to Aberrant Myelination in the Spinal Cord] Panlilio JM, Hammar KM, Aluru N, Hahn ME. February 2023

DNA Methylation As a Potential Mediator of the Association Between Indoor Air Pollution and Neurodevelopmental Delay in a South African Birth Cohort [Abstract DNA Methylation As a Potential Mediator of the Association Between Indoor Air Pollution and Neurodevelopmental Delay in a South African Birth Cohort] [Synopsis DNA Methylation As a Potential Mediator of the Association Between Indoor Air Pollution and Neurodevelopmental Delay in a South African Birth Cohort] Feil D, Abrishamcar S, Christensen GM, Vanker A, Koen N, Kilanowski A, Hoffman N, Wedderburn CJ, Donald KA, Kobor MS, Zar HJ, Stein DJ, Hüls A. February 2023

DUX4 Double Whammy: The Transcription Factor That Causes a Rare Muscular Dystrophy Also Kills the Precursors of the Human Nose [Abstract DUX4 Double Whammy: The Transcription Factor That Causes a Rare Muscular Dystrophy Also Kills the Precursors of the Human Nose] [Synopsis DUX4 Double Whammy: The Transcription Factor That Causes a Rare Muscular Dystrophy Also Kills the Precursors of the Human Nose] Inoue K, Bostan H, Browne MR, Bevis OF, Bortner CD, Moore SA, Stence AA, Martin NP, Chen SH, Burkholder AB, Li JL, Shaw ND. February 2023

Expansion of the Application Domain of a Macromolecular Ocular Irritation Test (OptiSafe™) [Abstract Expansion of the Application Domain of a Macromolecular Ocular Irritation Test (OptiSafe™)] [Synopsis Expansion of the Application Domain of a Macromolecular Ocular Irritation Test (OptiSafe™)] Lebrun S, Chavez S, Nguyen L, Chan R. February 2023

GLIS3 Regulates Transcription of Thyroid Hormone Biosynthetic Genes in Coordination With Other Thyroid Transcription Factors [Abstract GLIS3 Regulates Transcription of Thyroid Hormone Biosynthetic Genes in Coordination With Other Thyroid Transcription Factors] [Synopsis GLIS3 Regulates Transcription of Thyroid Hormone Biosynthetic Genes in Coordination With Other Thyroid Transcription Factors] Kang HS, Grimm SA, Jothi R, Santisteban P, Jetten AM. February 2023

High-throughput Screening of Toxicants That Modulate Extravillous Trophoblast Migration [Abstract High-throughput Screening of Toxicants That Modulate Extravillous Trophoblast Migration] [Synopsis High-throughput Screening of Toxicants That Modulate Extravillous Trophoblast Migration] Meakin C, Kim C, Lampert T, Aleksunes LM. February 2023

Ingested Polystyrene Nanospheres Translocate to Placenta and Fetal Tissues in Pregnant Rats: Potential Health Implications [Abstract Ingested Polystyrene Nanospheres Translocate to Placenta and Fetal Tissues in Pregnant Rats: Potential Health Implications] [Synopsis Ingested Polystyrene Nanospheres Translocate to Placenta and Fetal Tissues in Pregnant Rats: Potential Health Implications] Cary CM, DeLoid GM, Yang Z, Bitounis D, Polunas M, Goedken MJ, Buckley B, Cheatham B, Stapleton PA, Demokritou P. February 2023

Neighborhood Disadvantage and Immune-related Illnesses Among Residents Living in the Us Gulf States [Abstract Neighborhood Disadvantage and Immune-related Illnesses Among Residents Living in the Us Gulf States] [Synopsis Neighborhood Disadvantage and Immune-related Illnesses Among Residents Living in the Us Gulf States] Patel OP, Lawrence KG, Parks CG, Bodkin M, Jackson WB 3rd, Engel LS, Sandler DP. February 2023

Nicotine Exposure Decreases Likelihood of SARS-COV-2 RNA Expression and Neuropathology in the hACE2 Mouse Brain but Not Moribundity [Abstract Nicotine Exposure Decreases Likelihood of SARS-COV-2 RNA Expression and Neuropathology in the hACE2 Mouse Brain but Not Moribundity] [Synopsis Nicotine Exposure Decreases Likelihood of SARS-COV-2 RNA Expression and Neuropathology in the hACE2 Mouse Brain but Not Moribundity] Letsinger AC, Ward JM, Fannin RD, Mahapatra D, Bridge MF, Sills RC, Gerrish KE, Yakel JL. February 2023

Racial/Ethnic Differences in Associations Between Traumatic Childhood Experiences and Both Metabolic Syndrome Prevalence and Type 2 Diabetes Risk Among a Cohort of U.S. Women [Abstract Racial/Ethnic Differences in Associations Between Traumatic Childhood Experiences and Both Metabolic Syndrome Prevalence and Type 2 Diabetes Risk Among a Cohort of U.S. Women] [Synopsis Racial/Ethnic Differences in Associations Between Traumatic Childhood Experiences and Both Metabolic Syndrome Prevalence and Type 2 Diabetes Risk Among a Cohort of U.S. Women] Gaston SA, Riley NM, Parks CG, Woo JMP, Sandler DP, Jackson CL. February 2023

Association of Distance to Swine Concentrated Animal Feeding Operations With Immune-mediated Diseases: An Exploratory Gene-environment Study [Abstract Association of Distance to Swine Concentrated Animal Feeding Operations With Immune-mediated Diseases: An Exploratory Gene-environment Study] [Synopsis Association of Distance to Swine Concentrated Animal Feeding Operations With Immune-mediated Diseases: An Exploratory Gene-environment Study] Ayala-Ramirez M, MacNell N, McNamee LE, McGrath JA, Akhtari FS, Curry MD, Dunnon AK, Fessler MB, Garantziotis S, Parks CG, Fargo DC, Schmitt CP, Motsinger-Reif AA, Hall JE, Miller FW, Schurman SH. January 2023

Incident Dementia and Long-term Exposure to Constituents of Fine Particle Air Pollution: A National Cohort Study in the United States [Abstract Incident Dementia and Long-term Exposure to Constituents of Fine Particle Air Pollution: A National Cohort Study in the United States] [Synopsis Incident Dementia and Long-term Exposure to Constituents of Fine Particle Air Pollution: A National Cohort Study in the United States] Shi L, Zhu Q, Wang Y, Hao H, Zhang H, Schwartz J, Amini H, van Donkelaar A, Martin RV, Steenland K, Sarnat JA, Caudle WM, Ma T, Li H, Chang HH, Liu JZ, Wingo T, Mao X, Russell AG, Weber RJ, Liu P. January 2023

Paternal Phthalate Exposure-elicited Offspring Metabolic Disorders Are Associated With Altered Sperm Small RNAs in Mice [Abstract Paternal Phthalate Exposure-elicited Offspring Metabolic Disorders Are Associated With Altered Sperm Small RNAs in Mice] [Synopsis Paternal Phthalate Exposure-elicited Offspring Metabolic Disorders Are Associated With Altered Sperm Small RNAs in Mice] Liu J, Shi J, Hernandez R, Li X, Konchadi P, Miyake Y, Chen Q, Zhou T, Zhou C. January 2023

Perceptions and Experiences of Environmental Health and Risks Among Latina Mothers in Urban Los Angeles, California, USA [Abstract Perceptions and Experiences of Environmental Health and Risks Among Latina Mothers in Urban Los Angeles, California, USA] [Synopsis Perceptions and Experiences of Environmental Health and Risks Among Latina Mothers in Urban Los Angeles, California, USA] Kamai EM, Calderon A, Van Horne YO, Bastain TM, Breton CV, Johnston JE. January 2023

Sequencing-based Fine-mapping and in Silico Functional Characterization of the 10q24.32 Arsenic Metabolism Efficiency Locus Across Multiple Arsenic-exposed Populations [Abstract Sequencing-based Fine-mapping and in Silico Functional Characterization of the 10q24.32 Arsenic Metabolism Efficiency Locus Across Multiple Arsenic-exposed Populations] [Synopsis Sequencing-based Fine-mapping and in Silico Functional Characterization of the 10q24.32 Arsenic Metabolism Efficiency Locus Across Multiple Arsenic-exposed Populations] Chernoff MB, Delgado D, Tong L, Chen L, Oliva M, Tamayo LI, Best LG, Cole S, Jasmine F, Kibriya MG, Nelson H, Huang L, Haack K, Kent J, Umans JG, Graziano J, Navas-Acien A, Karagas MR, Ahsan H, Pierce BL. January 2023

Soy-Based Infant Formula Feeding and Uterine Fibroid Development in a Prospective Ultrasound Study of Black/African-American Women [Abstract Soy-Based Infant Formula Feeding and Uterine Fibroid Development in a Prospective Ultrasound Study of Black/African-American Women] [Synopsis Soy-Based Infant Formula Feeding and Uterine Fibroid Development in a Prospective Ultrasound Study of Black/African-American Women] Langton CR, Harmon QE, Upson K, Baird DD. January 2023

Urine Proteomics by Mass Spectrometry Identifies Proteins Involved in Key Pathogenic Pathways in Patients With Juvenile Dermatomyositis [Abstract Urine Proteomics by Mass Spectrometry Identifies Proteins Involved in Key Pathogenic Pathways in Patients With Juvenile Dermatomyositis] [Synopsis Urine Proteomics by Mass Spectrometry Identifies Proteins Involved in Key Pathogenic Pathways in Patients With Juvenile Dermatomyositis] Morales M, Alayi TD, Tawalbeh SM, Sydenstricker AV, Spathis R, Kim H, Kanneboyina N, Hathout Y, Rider LG. January 2023

An Interaction of Inorganic Arsenic Exposure With Body Weight and Composition on Type 2 Diabetes Indicators in Diversity Outbred Mice [Abstract An Interaction of Inorganic Arsenic Exposure With Body Weight and Composition on Type 2 Diabetes Indicators in Diversity Outbred Mice] [Synopsis An Interaction of Inorganic Arsenic Exposure With Body Weight and Composition on Type 2 Diabetes Indicators in Diversity Outbred Mice] Xenakis JG, Douillet C, Bell TA, Hock P, Farrington J, Liu T, Murphy CEY, Saraswatula A, Shaw GD, Nativio G, Shi Q, Venkatratnam A, Zou F, Fry RC, Stýblo M, Pardo-Manuel de Villena F. December 2022

Capillary Electrophoresis Mass Spectrometry Identifies New Isomers of Inositol Pyrophosphates in Mammalian Tissues [Abstract Capillary Electrophoresis Mass Spectrometry Identifies New Isomers of Inositol Pyrophosphates in Mammalian Tissues] [Synopsis Capillary Electrophoresis Mass Spectrometry Identifies New Isomers of Inositol Pyrophosphates in Mammalian Tissues] Qiu D, Gu C, Liu G, Ritter K, Eisenbeis VB, Bittner T, Gruzdev A, Seidel L, Bengsch B, Shears SB, Jessen HJ. December 2022

Early Life Organophosphate Ester Exposures and Bone Health at Age 12 Years: The Health Outcomes and Measures of the Environment (HOME) Study [Abstract Early Life Organophosphate Ester Exposures and Bone Health at Age 12 Years: The Health Outcomes and Measures of the Environment (HOME) Study] [Synopsis Early Life Organophosphate Ester Exposures and Bone Health at Age 12 Years: The Health Outcomes and Measures of the Environment (HOME) Study] Kuiper JR, Vuong AM, Lanphear BP, Calafat AM, Ospina M, Cecil KM, Xu Y, Yolton K, Kalkwarf HJ, Braun JM, Chen A, Buckley JP. December 2022

Elemental Dynamics in Hair Accurately Predict Future Autism Spectrum Disorder Diagnosis: An International Multi-Center Study [Abstract Elemental Dynamics in Hair Accurately Predict Future Autism Spectrum Disorder Diagnosis: An International Multi-Center Study] [Synopsis Elemental Dynamics in Hair Accurately Predict Future Autism Spectrum Disorder Diagnosis: An International Multi-Center Study] Austin C, Curtin P, Arora M, Reichenberg A, Curtin A, Iwai-Shimada M, Wright RO, Wright RJ, Remnelius KL, Isaksson J, Bölte S, Nakayama SF. December 2022

Fossil-fuel and Combustion-related Air Pollution and Hypertension in the Sister Study [Abstract Fossil-fuel and Combustion-related Air Pollution and Hypertension in the Sister Study] [Synopsis Fossil-fuel and Combustion-related Air Pollution and Hypertension in the Sister Study] Xu J, Niehoff NM, White AJ, Werder EJ, Sandler DP. December 2022

Nationwide Geospatial Analysis of County Racial and Ethnic Composition and Public Drinking Water Arsenic and Uranium [Abstract Nationwide Geospatial Analysis of County Racial and Ethnic Composition and Public Drinking Water Arsenic and Uranium] [Synopsis Nationwide Geospatial Analysis of County Racial and Ethnic Composition and Public Drinking Water Arsenic and Uranium] Martinez-Morata I, Bostick BC, Conroy-Ben O, Duncan DT, Jones MR, Spaur M, Patterson KP, Prins SJ, Navas-Acien A, Nigra AE. December 2022

Reproductive and Developmental Toxicity Following Exposure to Organophosphate Ester Flame Retardants and Plasticizers, Triphenyl Phosphate and Isopropylated Phenyl Phosphate, in Sprague Dawley Rats [Abstract Reproductive and Developmental Toxicity Following Exposure to Organophosphate Ester Flame Retardants and Plasticizers, Triphenyl Phosphate and Isopropylated Phenyl Phosphate, in Sprague Dawley Rats] [Synopsis Reproductive and Developmental Toxicity Following Exposure to Organophosphate Ester Flame Retardants and Plasticizers, Triphenyl Phosphate and Isopropylated Phenyl Phosphate, in Sprague Dawley Rats] Witchey SK, Sutherland V, Collins B, Roberts G, Shockley KR, Vallant M, Krause J, Cunny H, Waidyanatha S, Mylchreest E, Sparrow B, Moyer R, Behl M. December 2022

The Skin Is No Barrier to Mixtures: Air Pollutant Mixtures and Reported Psoriasis or Eczema in The Personalized Environment and Genes Study (PEGS) [Abstract The Skin Is No Barrier to Mixtures: Air Pollutant Mixtures and Reported Psoriasis or Eczema in The Personalized Environment and Genes Study (PEGS)] [Synopsis The Skin Is No Barrier to Mixtures: Air Pollutant Mixtures and Reported Psoriasis or Eczema in The Personalized Environment and Genes Study (PEGS)] Lowe ME, Akhtari FS, Potter TA, Fargo DC, Schmitt CP, Schurman SH, Eccles KM, Motsinger-Reif A, Hall JE, Messier KP. December 2022

Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings Through Transcriptomic Similarity Scoring [Abstract Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings Through Transcriptomic Similarity Scoring] [Synopsis Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings Through Transcriptomic Similarity Scoring] Koval LE, Carberry CK, Kim YH, McDermott E, Hartwell H, Jaspers I, Gilmour MI, Rager JE. December 2022

A Common Transcriptional Mechanism Involving R-loop and RNA Abasic Site Regulates an Enhancer RNA of APOE [Abstract A Common Transcriptional Mechanism Involving R-loop and RNA Abasic Site Regulates an Enhancer RNA of APOE] [Synopsis A Common Transcriptional Mechanism Involving R-loop and RNA Abasic Site Regulates an Enhancer RNA of APOE] Watts JA, Grunseich C, Rodriguez Y, Liu Y, Li D, Burdick JT, Bruzel A, Crouch RJ, Mahley RW, Wilson SH, Cheung VG. November 2022

Cardiac Development in the Presence of Cadmium: An in Vitro Study Using Human Embryonic Stem Cells and Cardiac Organoids [Abstract Cardiac Development in the Presence of Cadmium: An in Vitro Study Using Human Embryonic Stem Cells and Cardiac Organoids] [Synopsis Cardiac Development in the Presence of Cadmium: An in Vitro Study Using Human Embryonic Stem Cells and Cardiac Organoids] Wu X, Chen Y, Luz A, Hu G, Tokar EJ. November 2022

Contribution of Gut Bacteria to Arsenic Metabolism in the First Year of Life in a Prospective Birth Cohort [Abstract Contribution of Gut Bacteria to Arsenic Metabolism in the First Year of Life in a Prospective Birth Cohort] [Synopsis Contribution of Gut Bacteria to Arsenic Metabolism in the First Year of Life in a Prospective Birth Cohort] Laue HE, Moroishi Y, Palys TJ, Jackson BP, Madan JC, Karagas MR. November 2022

Identification of environmental factors that promote intestinal inflammation [Abstract Identification of environmental factors that promote intestinal inflammation] [Synopsis Identification of environmental factors that promote intestinal inflammation] Sanmarco LM, […], Quintana FJ. November 2022

Metabolomic, Lipidomic, Transcriptomic, and Metagenomic Analyses in Mice Exposed to PFOS and Fed Soluble and Insoluble Dietary Fibers [Abstract Metabolomic, Lipidomic, Transcriptomic, and Metagenomic Analyses in Mice Exposed to PFOS and Fed Soluble and Insoluble Dietary Fibers] [Synopsis Metabolomic, Lipidomic, Transcriptomic, and Metagenomic Analyses in Mice Exposed to PFOS and Fed Soluble and Insoluble Dietary Fibers] Deng P, Durham J, Liu J, Zhang X, Wang C, Li D, Gwag T, Ma M, Hennig B. November 2022

Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort [Abstract Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort] [Synopsis Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort] Akhtari FS, Lloyd D, Burkholder A, Tong X, House JS, Lee EY, Buse J, Schurman SH, Fargo DC, Schmitt CP, Hall J, Motsinger-Reif AA. November 2022

Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve Precision in Risk Characterization [Abstract Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve Precision in Risk Characterization] [Synopsis Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve Precision in Risk Characterization] Valdiviezo A, Brown GE, Michell AR, Trinconi CM, Bodke VV, Khetani SR, Luo YS, Chiu WA, Rusyn I. November 2022

Unequal Airborne Exposure to Toxic Metals Associated With Race, Ethnicity, and Segregation in the USA [Abstract Unequal Airborne Exposure to Toxic Metals Associated With Race, Ethnicity, and Segregation in the USA] [Synopsis Unequal Airborne Exposure to Toxic Metals Associated With Race, Ethnicity, and Segregation in the USA] Kodros JK, Bell ML, Dominici F, L'Orange C, Godri Pollitt KJ, Weichenthal S, Wu X, Volckens J. November 2022

Aerobic Bioaugmentation to Decrease Polychlorinated Biphenyl (PCB) Emissions From Contaminated Sediments to Air [Abstract Aerobic Bioaugmentation to Decrease Polychlorinated Biphenyl (PCB) Emissions From Contaminated Sediments to Air] [Synopsis Aerobic Bioaugmentation to Decrease Polychlorinated Biphenyl (PCB) Emissions From Contaminated Sediments to Air] Bako CM, Martinez A, Ewald JM, Hua JBX, Ramotowski DJ, Dong Q, Schnoor JL, Mattes TE. October 2022

Blood Concentrations of Per- and Polyfluoroalkyl Substances Are Associated With Autoimmune-like Effects in American Alligators From Wilmington, North Carolina [Abstract Blood Concentrations of Per- and Polyfluoroalkyl Substances Are Associated With Autoimmune-like Effects in American Alligators From Wilmington, North Carolina] [Synopsis Blood Concentrations of Per- and Polyfluoroalkyl Substances Are Associated With Autoimmune-like Effects in American Alligators From Wilmington, North Carolina] Guillette TC, Jackson TW, Guillette M, McCord J, Belcher SM. October 2022

Fetal Growth Trajectories of Babies Born Large-for-gestational Age in the LIFECODES Fetal Growth Study [Abstract Fetal Growth Trajectories of Babies Born Large-for-gestational Age in the LIFECODES Fetal Growth Study] [Synopsis Fetal Growth Trajectories of Babies Born Large-for-gestational Age in the LIFECODES Fetal Growth Study] Bommarito PA, Cantonwine DE, Stevens DR, Welch BM, Davalos AD, Zhao S, McElrath TF, Ferguson KK. October 2022

Longitudinal Serological Surveillance for COVID-19 Antibodies After Infection and Vaccination [Abstract Longitudinal Serological Surveillance for COVID-19 Antibodies After Infection and Vaccination] [Synopsis Longitudinal Serological Surveillance for COVID-19 Antibodies After Infection and Vaccination] McGee C, Shi M, House J, Drude A, Gonzalez G, Martin N, Chen SH, Rogers H, Njunge A, Hodge X, Mosley B, George M, Agrawal R, Wild C, Smith C, Brown A, Barber L, Garantziotis S. October 2022

Peripheral Immune Cell Composition Is Altered in Women Before and After a Hypertension Diagnosis [Abstract Peripheral Immune Cell Composition Is Altered in Women Before and After a Hypertension Diagnosis] [Synopsis Peripheral Immune Cell Composition Is Altered in Women Before and After a Hypertension Diagnosis] Kresovich JK, Xu Z, O'Brien KM, Parks CG, Weinberg CR, Sandler DP, Taylor JA. October 2022

Use of Straighteners and Other Hair Products and Incident Uterine Cancer [Abstract Use of Straighteners and Other Hair Products and Incident Uterine Cancer] [Synopsis Use of Straighteners and Other Hair Products and Incident Uterine Cancer] Chang CJ, O'Brien KM, Keil AP, Gaston SA, Jackson CL, Sandler DP, White AJ. October 2022

Accumulation and Depuration of Microplastic Fibers, Fragments, and Tire Particles in the Eastern Oyster, Crassostrea Virginica: A Toxicokinetic Approach [Abstract Accumulation and Depuration of Microplastic Fibers, Fragments, and Tire Particles in the Eastern Oyster, Crassostrea Virginica: A Toxicokinetic Approach] [Synopsis Accumulation and Depuration of Microplastic Fibers, Fragments, and Tire Particles in the Eastern Oyster, Crassostrea Virginica: A Toxicokinetic Approach] Weinstein JE, Ertel BM, Gray AD. September 2022

A Geospatial Modeling Approach to Quantifying the Risk of Exposure to Environmental Chemical Mixtures Via a Common Molecular Target [Abstract A Geospatial Modeling Approach to Quantifying the Risk of Exposure to Environmental Chemical Mixtures Via a Common Molecular Target] [Synopsis A Geospatial Modeling Approach to Quantifying the Risk of Exposure to Environmental Chemical Mixtures Via a Common Molecular Target] Eccles KM, Karmaus AL, Kleinstreuer NC, Parham F, Rider CV, Wambaugh JF, Messier KP. September 2022

Associations Between Airborne Crude Oil Chemicals and Symptom-based Asthma [Abstract Associations Between Airborne Crude Oil Chemicals and Symptom-based Asthma] [Synopsis Associations Between Airborne Crude Oil Chemicals and Symptom-based Asthma] Lawrence KG, Niehoff NM, Keil AP, Braxton Jackson W 2nd, Christenbury K, Stewart PA, Stenzel MR, Huynh TB, Groth CP, Ramachandran G, Banerjee S, Pratt GC, Curry MD, Engel LS, Sandler DP. September 2022

Contribution of the Wolffian Duct Mesenchyme to the Formation of the Female Reproductive Tract [Abstract Contribution of the Wolffian Duct Mesenchyme to the Formation of the Female Reproductive Tract] [Synopsis Contribution of the Wolffian Duct Mesenchyme to the Formation of the Female Reproductive Tract] Zhao F, Grimm SA, Jia S, Yao HH. September 2022

Homologous Recombination-deficient Mutation Cluster in Tumor Suppressor RAD51C Identified by Comprehensive Analysis of Cancer Variants [Abstract Homologous Recombination-deficient Mutation Cluster in Tumor Suppressor RAD51C Identified by Comprehensive Analysis of Cancer Variants] [Synopsis Homologous Recombination-deficient Mutation Cluster in Tumor Suppressor RAD51C Identified by Comprehensive Analysis of Cancer Variants] Prakash R, Rawal Y, Sullivan MR, Grundy MK, Bret H, Mihalevic MJ, Rein HL, Baird JM, Darrah K, Zhang F, Wang R, Traina TA, Radke MR, Kaufmann SH, Swisher EM, Guérois R, Modesti M, Sung P, Jasin M, Bernstein KA. September 2022

Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase [Abstract Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase] [Synopsis Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase] Klemm BP, Singh D, Smith CE, Hsu AL, Dillard LB, Krahn JM, London RE, Mueller GA, Borgnia MJ, Schaaper RM. September 2022

Wildfires and Extracellular Vesicles: Exosomal Micrornas As Mediators of Cross-tissue Cardiopulmonary Responses to Biomass Smoke [Abstract Wildfires and Extracellular Vesicles: Exosomal Micrornas As Mediators of Cross-tissue Cardiopulmonary Responses to Biomass Smoke] [Synopsis Wildfires and Extracellular Vesicles: Exosomal Micrornas As Mediators of Cross-tissue Cardiopulmonary Responses to Biomass Smoke] Carberry CK, Koval LE, Payton A, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M and Rager JE. September 2022

An application of group-based trajectory modeling to define fetal growth phenotypes among small-for-gestational-age births in the LIFECODES Fetal Growth Study [Abstract An application of group-based trajectory modeling to define fetal growth phenotypes among small-for-gestational-age births in the LIFECODES Fetal Growth Study] [Synopsis An application of group-based trajectory modeling to define fetal growth phenotypes among small-for-gestational-age births in the LIFECODES Fetal Growth Study] Bommarito PA, Cantonwine DE, Stevens DR, Welch BM, Davalos AD, Zhao S, McElrath TF, Ferguson KK. August 2022

Cancer Hazard Evaluations for Contemporary Needs: Highlights From New NTP Evaluations and Methodological Advancements [Abstract Cancer Hazard Evaluations for Contemporary Needs: Highlights From New NTP Evaluations and Methodological Advancements] [Synopsis Cancer Hazard Evaluations for Contemporary Needs: Highlights From New NTP Evaluations and Methodological Advancements] Lunn RM, Mehta SS, Jahnke GD, Wang A, Wolfe MS, Berridge BR. August 2022

Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk [Abstract Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk] [Synopsis Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk] Eid A, Mhatre-Winters I, Sammoura FM, Edler MK, von Stein R, Hossain MM, Han Y, Lisci M, Carney K, Konsolaki M, Hart RP, Bennett JW, Richardson JR. August 2022

Exposure to Perfluoroalkyl Substances and Risk of Hepatocellular Carcinoma in a Multiethnic Cohort [Abstract Exposure to Perfluoroalkyl Substances and Risk of Hepatocellular Carcinoma in a Multiethnic Cohort] [Synopsis Exposure to Perfluoroalkyl Substances and Risk of Hepatocellular Carcinoma in a Multiethnic Cohort] Goodrich JA, Walker D, Lin X, Wang H, Lim T, McConnell R, Conti DV, Chatzi L, Setiawan VW. August 2022

Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease [Abstract Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease] [Synopsis Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease] Frazier MN, Wilson IM, Krahn JM, Butay KJ, Dillard LB, Borgnia MJ, Stanley RE. August 2022

Individual nutrition is associated with altered gut microbiome composition for adults with food insecurity [Abstract Individual nutrition is associated with altered gut microbiome composition for adults with food insecurity] [Synopsis Individual nutrition is associated with altered gut microbiome composition for adults with food insecurity] Bixby M, Gennings C, Malecki KMC, Sethi AK, Safdar N, Peppard PE, Eggers S. August 2022

Mechanism-driven Modeling of Chemical Hepatotoxicity Using Structural Alerts and an in Vitro Screening Assay [Abstract Mechanism-driven Modeling of Chemical Hepatotoxicity Using Structural Alerts and an in Vitro Screening Assay] [Synopsis Mechanism-driven Modeling of Chemical Hepatotoxicity Using Structural Alerts and an in Vitro Screening Assay] Jia X, Wen X, Russo DP, Aleksunes LM, Zhu H. August 2022

Natural Locus Coeruleus Dynamics During Feeding [Abstract Natural Locus Coeruleus Dynamics During Feeding] [Synopsis Natural Locus Coeruleus Dynamics During Feeding] Sciolino NR, Hsiang M, Mazzone CM, Wilson LR, Plummer NW, Amin J, Smith KG, McGee CA, Fry SA, Yang CX, Powell JM, Bruchas MR, Kravitz AV, Cushman JD, Krashes MJ, Cui G, Jensen P. August 2022

Racial Residential Segregation Shapes the Relationship Between Early Childhood Lead Exposure and Fourth-grade Standardized Test Scores [Abstract Racial Residential Segregation Shapes the Relationship Between Early Childhood Lead Exposure and Fourth-grade Standardized Test Scores] [Synopsis Racial Residential Segregation Shapes the Relationship Between Early Childhood Lead Exposure and Fourth-grade Standardized Test Scores] Bravo MA, Zephyr D, Kowal D, Ensor K, Miranda ML. August 2022

Residential Wood Burning and Pulmonary Function in the Agricultural Lung Health Study [Abstract Residential Wood Burning and Pulmonary Function in the Agricultural Lung Health Study] [Synopsis Residential Wood Burning and Pulmonary Function in the Agricultural Lung Health Study] M White JD, Wyss AB, Hoang TT, Lee M, Richards M, Parks CG, Beane-Freeman LE, Hankinson JL, Umbach DM, London SJ. August 2022

Structural Insight and Characterization of Human Twinkle Helicase in Mitochondrial Disease [Abstract Structural Insight and Characterization of Human Twinkle Helicase in Mitochondrial Disease] [Synopsis Structural Insight and Characterization of Human Twinkle Helicase in Mitochondrial Disease] Riccio AA, Bouvette J, Perera L, Longley MJ, Krahn JM, Williams JG, Dutcher R, Borgnia MJ, and Copeland WC. August 2022

Unconventional oil and gas development exposure and risk of childhood acute lymphoblastic leukemia: a case-control study in Pennsylvania [Abstract Unconventional oil and gas development exposure and risk of childhood acute lymphoblastic leukemia: a case-control study in Pennsylvania] [Synopsis Unconventional oil and gas development exposure and risk of childhood acute lymphoblastic leukemia: a case-control study in Pennsylvania] Clark CJ, Johnson NP, Soriano M Jr, Warren JL, Sorrentino KM, Kadan-Lottick NS, Saiers JE, Ma X, Deziel NC. August 2022

Analysis of Diverse Double-strand Break Synapsis With Polλ Reveals Basis for Unique Substrate Specificity in Nonhomologous End-joining [Abstract Analysis of Diverse Double-strand Break Synapsis With Polλ Reveals Basis for Unique Substrate Specificity in Nonhomologous End-joining] [Synopsis Analysis of Diverse Double-strand Break Synapsis With Polλ Reveals Basis for Unique Substrate Specificity in Nonhomologous End-joining] Kaminski AM, Chiruvella KK, Ramsden DA, Bebenek K, Kunkel TA, Pedersen LC. July 2022

Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 U.S. Cohorts [Abstract Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 U.S. Cohorts] [Synopsis Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 U.S. Cohorts] Welch BM, Keil AP, Buckley JP, Calafat AM, Christenbury KE, Engel SM, O'Brien KM, Rosen EM, James-Todd T, Zota AR, Ferguson KK; Pooled Phthalate Exposure and Preterm Birth Study Group. July 2022

High-resolution Structures of the SAMHD1 dGTPase Homolog From Leeuwenhoekiella Blandensis Reveal a Novel Mechanism of Allosteric Activation by dATP [Abstract High-resolution Structures of the SAMHD1 dGTPase Homolog From Leeuwenhoekiella Blandensis Reveal a Novel Mechanism of Allosteric Activation by dATP] [Synopsis High-resolution Structures of the SAMHD1 dGTPase Homolog From Leeuwenhoekiella Blandensis Reveal a Novel Mechanism of Allosteric Activation by dATP] Klemm BP, Sikkema AP, Hsu AL, Horng JC, Hall TMT, Borgnia MJ, Schaaper RM. July 2022

Lactational Delivery of Triclosan Promotes Non-alcoholic Fatty Liver Disease in Newborn Mice [Abstract Lactational Delivery of Triclosan Promotes Non-alcoholic Fatty Liver Disease in Newborn Mice] [Synopsis Lactational Delivery of Triclosan Promotes Non-alcoholic Fatty Liver Disease in Newborn Mice] Weber AA, Yang X, Mennillo E, Ding J, Watrous JD, Jain M, Chen S, Karin M, Tukey RH. July 2022

Prior Exposure to Microcystin Alters Host Gut Resistome and Is Associated With Dysregulated Immune Homeostasis in Translatable Mouse Models [Abstract Prior Exposure to Microcystin Alters Host Gut Resistome and Is Associated With Dysregulated Immune Homeostasis in Translatable Mouse Models] [Synopsis Prior Exposure to Microcystin Alters Host Gut Resistome and Is Associated With Dysregulated Immune Homeostasis in Translatable Mouse Models] Saha P, Bose D, Stebliankin V, Cickovski T, Seth RK, Porter DE, Brooks BW, Mathee K, Narasimhan G, Colwell R, Scott GI, Chatterjee S. July 2022

Somatic Cell Fate Maintenance in Mouse Fetal Testes Via Autocrine/Paracrine Action of Amh and Activin B. [Abstract Somatic Cell Fate Maintenance in Mouse Fetal Testes Via Autocrine/Paracrine Action of Amh and Activin B.] [Synopsis Somatic Cell Fate Maintenance in Mouse Fetal Testes Via Autocrine/Paracrine Action of Amh and Activin B.] Rodriguez KF, Brown PR, Amato CM, Nicol B, Liu CF, Xu X, Yao HH. July 2022

Vitamin D Concentrations and Breast Cancer Incidence Among Black/African American and Non-black Hispanic/Latina Women [Abstract Vitamin D Concentrations and Breast Cancer Incidence Among Black/African American and Non-black Hispanic/Latina Women] [Synopsis Vitamin D Concentrations and Breast Cancer Incidence Among Black/African American and Non-black Hispanic/Latina Women] O'Brien KM, Harmon QE, Jackson CL, Diaz-Santana MV, Taylor JA, Weinberg CR, Sandler DP. July 2022

A Global Lipid Map Reveals Host Dependency Factors Conserved Across SARS-CoV-2 Variants [Abstract A Global Lipid Map Reveals Host Dependency Factors Conserved Across SARS-CoV-2 Variants] [Synopsis A Global Lipid Map Reveals Host Dependency Factors Conserved Across SARS-CoV-2 Variants] Farley SE, Kyle JE, Leier HC, Bramer LM, Weinstein JB, Bates TA, Lee JY, Metz TO, Schultz C, Tafesse FG. June 2022

Environmental Mixtures and Breast Cancer: Identifying Co-exposure Patterns Between Understudied Vs Breast Cancer-associated Chemicals Using Chemical Inventory Informatics [Abstract Environmental Mixtures and Breast Cancer: Identifying Co-exposure Patterns Between Understudied Vs Breast Cancer-associated Chemicals Using Chemical Inventory Informatics] [Synopsis Environmental Mixtures and Breast Cancer: Identifying Co-exposure Patterns Between Understudied Vs Breast Cancer-associated Chemicals Using Chemical Inventory Informatics] Koval LE, Dionisio KL, Friedman KP, Isaacs KK, Rager JE. June 2022

Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies [Abstract Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies] [Synopsis Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies] Karmaus AL, Mansouri K, To KT, Blake B, Fitzpatrick J, Strickland J, Patlewicz G, Allen D, Casey W, Kleinstreuer N. June 2022

Expanded Assessment of Xenobiotic Associations With Antinuclear Antibodies in the United States, 1988-2012 [Abstract Expanded Assessment of Xenobiotic Associations With Antinuclear Antibodies in the United States, 1988-2012] [Synopsis Expanded Assessment of Xenobiotic Associations With Antinuclear Antibodies in the United States, 1988-2012] Dinse GE, Co CA, Parks CG, Weinberg CR, Xie G, Chan EKL, Birnbaum LS. June 2022

Future Flooding Increases Unequal Exposure Risks to Relic Industrial Pollution [Abstract Future Flooding Increases Unequal Exposure Risks to Relic Industrial Pollution] [Synopsis Future Flooding Increases Unequal Exposure Risks to Relic Industrial Pollution] Marlow T, Elliot JR, Frickel S. June 2022

Generation of a Homozygous Mutant Drug Transporter (ABCB1) Knockout Line in the Sea Urchin Lytechinus Pictus [Abstract Generation of a Homozygous Mutant Drug Transporter (ABCB1) Knockout Line in the Sea Urchin Lytechinus Pictus] [Synopsis Generation of a Homozygous Mutant Drug Transporter (ABCB1) Knockout Line in the Sea Urchin Lytechinus Pictus] Vyas H, Schrankel CS, Espinoza JA, Mitchell KL, Nesbit KT, Jackson E, Chang N, Lee Y, Warner J, Reitzel A, Lyons DC, Hamdoun A. June 2022

PFAS and PBDEs in Traditional Subsistence Foods From Sivuqaq, Alaska [Abstract PFAS and PBDEs in Traditional Subsistence Foods From Sivuqaq, Alaska] [Synopsis PFAS and PBDEs in Traditional Subsistence Foods From Sivuqaq, Alaska] Byrne S, Seguinot-Medina S, Waghiyi V, Apatiki E, Immingan T, Miller P, von Hippel FA, Buck CL, Carpenter DO. June 2022

Associating Increased Chemical Exposure to Hurricane Harvey in a Longitudinal Panel Using Silicone Wristbands [Abstract Associating Increased Chemical Exposure to Hurricane Harvey in a Longitudinal Panel Using Silicone Wristbands] [Synopsis Associating Increased Chemical Exposure to Hurricane Harvey in a Longitudinal Panel Using Silicone Wristbands] Samon SM, Rohlman D, Tidwell LG, Hoffman PD, Oluyomi AO, Anderson KA. May 2022

Depot Medroxyprogesterone Acetate Use and the Development and Progression of Uterine Leiomyoma [Abstract Depot Medroxyprogesterone Acetate Use and the Development and Progression of Uterine Leiomyoma] [Synopsis Depot Medroxyprogesterone Acetate Use and the Development and Progression of Uterine Leiomyoma] Harmon QE, Patchel SA, Zhao S, Umbach DM, Cooper TE, Baird DD. May 2022

Exploring the Influence of Experimental Design on Toxicity Outcomes in Zebrafish Embryo Tests [Abstract Exploring the Influence of Experimental Design on Toxicity Outcomes in Zebrafish Embryo Tests] [Synopsis Exploring the Influence of Experimental Design on Toxicity Outcomes in Zebrafish Embryo Tests] Hsieh JH, Behl M, Parham F, Ryan K. May 2022

IL-22 Regulates Inflammatory Responses to Agricultural Dust-induced Airway Inflammation [Abstract IL-22 Regulates Inflammatory Responses to Agricultural Dust-induced Airway Inflammation] [Synopsis IL-22 Regulates Inflammatory Responses to Agricultural Dust-induced Airway Inflammation] Ulu A, Sveiven S, Bilg A, Velazquez JV, Diaz M, Mukherjee M, Yuil-Valdes AG, Kota S, Burr A, Najera A, Nordgren TM. May 2022

Point-of-use Carbon-block Drinking Water Filters Change Gut Microbiome of Larval Zebrafish [Abstract Point-of-use Carbon-block Drinking Water Filters Change Gut Microbiome of Larval Zebrafish] [Synopsis Point-of-use Carbon-block Drinking Water Filters Change Gut Microbiome of Larval Zebrafish] Wu CC, Connell M, Zarb A, Akemann C, Morgan S, McElmurry SP, Love NG, Baker TR. May 2022

Pulmonary Function and Blood DNA Methylation: A Multi-ancestry Epigenome-wide Association Meta-analysis [Abstract Pulmonary Function and Blood DNA Methylation: A Multi-ancestry Epigenome-wide Association Meta-analysis] [Synopsis Pulmonary Function and Blood DNA Methylation: A Multi-ancestry Epigenome-wide Association Meta-analysis] Lee M, Huan T, McCartney DL, Chittoor G, de Vries M, Lahousse L, Nguyen JN, Brody JA, Castillo-Fernandez J, Terzikhan N, Qi C, Joehanes R, Min JL, Smilnak GJ, Shaw JR, Yang CX, Colicino E, Hoang TT, Bermingham ML, Xu H, Justice AE, Xu CJ, Rich SS, Cox SR, Vonk JM, Prokić I, Sotoodehnia N, Tsai PC, Schwartz JD, Leung JM, Sikdar S, Walker RM, Harris SE, van der Plaat DA, Van Den Berg DJ, Bartz TM, Spector TD, Vokonas PS, Marioni RE, Taylor AM, Liu Y, Barr RG, Lange LA, Baccarelli AA, Obeidat M, Fornage M, Wang T, Ward JM, Motsinger-Reif AA, Hemani G, Koppelman GH, Bell JT, Gharib SA, Brusselle G, Boezen HM, North KE, Levy D, Evans KL, Dupuis J, Breeze CE, Manichaikul A, London SJ; BIOS consortium, GoDMC. May 2022

Questionnaire-based Exposome-wide Association Studies (ExWAS) Reveal Expected and Novel Risk Factors Associated With Cardiovascular Outcomes in the Personalized Environment and Genes Study [Abstract Questionnaire-based Exposome-wide Association Studies (ExWAS) Reveal Expected and Novel Risk Factors Associated With Cardiovascular Outcomes in the Personalized Environment and Genes Study] [Synopsis Questionnaire-based Exposome-wide Association Studies (ExWAS) Reveal Expected and Novel Risk Factors Associated With Cardiovascular Outcomes in the Personalized Environment and Genes Study] Lee EY, Akhtari F, House JS, Simpson RJ Jr, Schmitt CP, Fargo DC, Schurman SH, Hall JE, Motsinger-Reif AA. May 2022

Systemic Exposure and Urinary Excretion of Vanadium Following Perinatal Subchronic Exposure to Vanadyl Sulfate and Sodium Metavanadate Via Drinking Water [Abstract Systemic Exposure and Urinary Excretion of Vanadium Following Perinatal Subchronic Exposure to Vanadyl Sulfate and Sodium Metavanadate Via Drinking Water] [Synopsis Systemic Exposure and Urinary Excretion of Vanadium Following Perinatal Subchronic Exposure to Vanadyl Sulfate and Sodium Metavanadate Via Drinking Water] Waidyanatha S, Weber FX, Fallacara DM, Harrington JM, Levine K, Robinson VG, Sparrow BR, Stout MD, Fernando R, Hooth MJ, Xie G, Roberts GK. May 2022

A High-throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells [Abstract A High-throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells] [Synopsis A High-throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells] Blake BE, Rickard BP, Fenton SE. April 2022

Breast Cancer is Linked to Ambient Radioactive Particles [Abstract Breast Cancer is Linked to Ambient Radioactive Particles] [Synopsis Breast Cancer is Linked to Ambient Radioactive Particles] White AJ, Gregoire AM, Fisher JA, Medgyesi DN, Li L, Koutrakis P, Sandler DP, Jones RR. April 2022

Epigenome-wide Association Study of Bronchopulmonary Dysplasia in Preterm Infants: Results From the Discovery-BPD Program [Abstract Epigenome-wide Association Study of Bronchopulmonary Dysplasia in Preterm Infants: Results From the Discovery-BPD Program] [Synopsis Epigenome-wide Association Study of Bronchopulmonary Dysplasia in Preterm Infants: Results From the Discovery-BPD Program] Wang X, Cho HY, Campbell MR, Panduri V, Coviello S, Caballero MT, Sambandan D, Kleeberger SR, Polack FP, Ofman G, Bell DA. April 2022

Exploring the Link Between Phthalates and Fetal Health [Abstract Exploring the Link Between Phthalates and Fetal Health] [Synopsis Exploring the Link Between Phthalates and Fetal Health] Stevens DR, Bommarito PA, Keil AP, McElrath TF, Trasande L, Barrett ES, Bush NR, Nguyen RHN, Sathyanarayana S, Swan S, Ferguson KK. April 2022

Leveraging Deep Learning to Predict Abdominal Age, Prevent Disease [Abstract Leveraging Deep Learning to Predict Abdominal Age, Prevent Disease] [Synopsis Leveraging Deep Learning to Predict Abdominal Age, Prevent Disease] Le Goallec A, Diai S, Collin S, Prost JB, Vincent T, Patel CJ. April 2022

Maternal Phthalate and Bisphenol Urine Concentrations During Pregnancy and Early Markers of Arterial Health in Children [Abstract Maternal Phthalate and Bisphenol Urine Concentrations During Pregnancy and Early Markers of Arterial Health in Children] [Synopsis Maternal Phthalate and Bisphenol Urine Concentrations During Pregnancy and Early Markers of Arterial Health in Children] Blaauwendraad SM, Gaillard R, Santos S, Sol CM, Kannan K, Trasande L, Jaddoe VWV. April 2022

New Approach Paves the Way for Large-Scale Genome Integrity Studies [Abstract New Approach Paves the Way for Large-Scale Genome Integrity Studies] [Synopsis New Approach Paves the Way for Large-Scale Genome Integrity Studies] Maslov AY, Makhortov S, Sun S, Heid J, Dong X, Lee M, Vijg J. April 2022

Novel Genetic Sensor Traces Environmental Genotoxic Stress Associated With Parkinson's Disease [Abstract Novel Genetic Sensor Traces Environmental Genotoxic Stress Associated With Parkinson's Disease] [Synopsis Novel Genetic Sensor Traces Environmental Genotoxic Stress Associated With Parkinson's Disease] El-Saadi MW, Tian X, Grames M, Ren M, Keys K, Li H, Knott E, Yin H, Huang S, Lu XH. April 2022

Persistence of Risk for Type 2 Diabetes After Gestational Diabetes Mellitus [Abstract Persistence of Risk for Type 2 Diabetes After Gestational Diabetes Mellitus] [Synopsis Persistence of Risk for Type 2 Diabetes After Gestational Diabetes Mellitus] Diaz-Santana MV, O'Brien KM, Park YM, Sandler DP, Weinberg CR. April 2022

Prenatal Exposure to Chemical Mixtures Worsens Working Memory in Adolescents [Abstract Prenatal Exposure to Chemical Mixtures Worsens Working Memory in Adolescents] [Synopsis Prenatal Exposure to Chemical Mixtures Worsens Working Memory in Adolescents] Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Korrick SA. April 2022

Prenatal Phthalate Exposure and Child Weight and Adiposity From in Utero to 6 Years of Age [Abstract Prenatal Phthalate Exposure and Child Weight and Adiposity From in Utero to 6 Years of Age] [Synopsis Prenatal Phthalate Exposure and Child Weight and Adiposity From in Utero to 6 Years of Age] Ferguson KK, Bommarito PA, Arogbokun O, Rosen EM, Keil AP, Zhao S, Barrett ES, Nguyen RHN, Bush NR, Trasande L, McElrath TF, Swan SH, Sathyanarayana S. April 2022

Researchers Identify Risk Factors for Disease Flares After COVID-19 Vaccination [Abstract Researchers Identify Risk Factors for Disease Flares After COVID-19 Vaccination] [Synopsis Researchers Identify Risk Factors for Disease Flares After COVID-19 Vaccination] Rider LG, Parks CG, Wilkerson J, Schiffenbauer AI, Kwok RK, Noroozi Farhadi P, Nazir S, Ritter R, Sirotich E, Kennedy K, Larche MJ, Levine M, Sattui SE, Liew JW, Harrison CO, Moni TT, Miller AK, Putman M, Hausmann J, Simard JF, Sparks JA, Miller FW. April 2022

SIRT1 Regulates Cardiomyocyte Alignment During Maturation [Abstract SIRT1 Regulates Cardiomyocyte Alignment During Maturation] [Synopsis SIRT1 Regulates Cardiomyocyte Alignment During Maturation] Fang Y, Fan W, Xu X, Janoshazi AK, Fargo DC, Li X. April 2022

Analysis of the Novel NCWELL Database Highlights Two Decades of Co-occurrence of Toxic Metals in North Carolina Private Well Water: Public Health and Environmental Justice Implications [Abstract Analysis of the Novel NCWELL Database Highlights Two Decades of Co-occurrence of Toxic Metals in North Carolina Private Well Water: Public Health and Environmental Justice Implications] [Synopsis Analysis of the Novel NCWELL Database Highlights Two Decades of Co-occurrence of Toxic Metals in North Carolina Private Well Water: Public Health and Environmental Justice Implications] Eaves LA, Keil AP, Rager JE, George A, Fry RC. March 2022

Association of Tropical Cyclones With County-level Mortality in the US [Abstract Association of Tropical Cyclones With County-level Mortality in the US] [Synopsis Association of Tropical Cyclones With County-level Mortality in the US] Parks RM, Benavides J, Anderson GB, Nethery RC, Navas-Acien A, Dominici F, Ezzati M, Kioumourtzoglou MA. March 2022

Associations Between the Maternal Exposome and Metabolome During Pregnancy [Abstract Associations Between the Maternal Exposome and Metabolome During Pregnancy] [Synopsis Associations Between the Maternal Exposome and Metabolome During Pregnancy] Chen M, Guan Y, Huang R, Duan J, Zhou J, Chen T, Wang X, Xia Y, London SJ. March 2022

Biosensor Applications in Contaminated Estuaries: Implications For Disaster Research Response [Abstract Biosensor Applications in Contaminated Estuaries: Implications For Disaster Research Response] [Synopsis Biosensor Applications in Contaminated Estuaries: Implications For Disaster Research Response] Camargo K, Vogelbein MA, Horney JA, Dellapenna TM, Knap AH, Sericano JL, Wade TL, McDonald TJ, Chiu WA, Unger MA. March 2022

Cross-sectional Neuromuscular Phenotyping Study of Patients with Arhinia with SMCHD1 Variants [Abstract Cross-sectional Neuromuscular Phenotyping Study of Patients with Arhinia with SMCHD1 Variants] [Synopsis Cross-sectional Neuromuscular Phenotyping Study of Patients with Arhinia with SMCHD1 Variants] Mohassel P, Chang N, Inoue K, Delaney A, Hu Y, Donkervoort S, Saade D, Billioux BJ, Meader B, Volochayev R, Konersman CG, Kaindl AM, Cho CH, Russell B, Rodriguez A, Foster KW, Foley AR, Moore SA, Jones PL, Bonnemann CG, Jones T, Shaw ND. March 2022

Maternal, Placental, and Fetal Distribution of Titanium After Repeated Titanium Dioxide Nanoparticle Inhalation Through Pregnancy [Abstract Maternal, Placental, and Fetal Distribution of Titanium After Repeated Titanium Dioxide Nanoparticle Inhalation Through Pregnancy] [Synopsis Maternal, Placental, and Fetal Distribution of Titanium After Repeated Titanium Dioxide Nanoparticle Inhalation Through Pregnancy] D'Errico JN, Doherty C, Reyes George JJ, Buckley B, Stapleton PA. March 2022

Placenta and Fetal Brain Share a Neurodevelopmental Disorder DNA Methylation Profile in a Mouse Model of Prenatal PCB Exposure [Abstract Placenta and Fetal Brain Share a Neurodevelopmental Disorder DNA Methylation Profile in a Mouse Model of Prenatal PCB Exposure] [Synopsis Placenta and Fetal Brain Share a Neurodevelopmental Disorder DNA Methylation Profile in a Mouse Model of Prenatal PCB Exposure] Laufer BI, Neier K, Valenzuela AE, Yasui DH, Schmidt RJ, Lein PJ, LaSalle JM. March 2022

Pregnancy Depends on Crosstalk Among Uterine Microenvironments [Abstract Pregnancy Depends on Crosstalk Among Uterine Microenvironments] [Synopsis Pregnancy Depends on Crosstalk Among Uterine Microenvironments] Li R, Wang TY, Xu X, Emery O, Yi M, Wu SP, DeMayo FJ. March 2022

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS) [Abstract Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)] [Synopsis Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)] Kirkwood KI, Fleming J, Nguyen H, Reif DM, Baker ES, Belcher SM. March 2022

Validation of Blood Arsenic and Manganese Assessment From Archived Clotted Erythrocyte Fraction in an Urban Cohort of Mother-Child Dyads [Abstract Validation of Blood Arsenic and Manganese Assessment From Archived Clotted Erythrocyte Fraction in an Urban Cohort of Mother-Child Dyads] [Synopsis Validation of Blood Arsenic and Manganese Assessment From Archived Clotted Erythrocyte Fraction in an Urban Cohort of Mother-Child Dyads] Haque E, Moran ME, Wang H, Adamcakova-Dodd A, Thorne PS. March 2022

A Data Mining Approach Reveals Chemicals Detected at Higher Levels in Non-hispanic Black Women Target Preterm Birth Genes and Pathways [Abstract A Data Mining Approach Reveals Chemicals Detected at Higher Levels in Non-hispanic Black Women Target Preterm Birth Genes and Pathways] [Synopsis A Data Mining Approach Reveals Chemicals Detected at Higher Levels in Non-hispanic Black Women Target Preterm Birth Genes and Pathways] Harris SM, Colacino J, Buxton M, Croxton L, Nguyen V, Loch-Caruso R, Bakulski KM. February 2022

A Neutrophil/TGF-β Axis Limits the Pathogenicity of Allergen-specific CD4+ T Cells [Abstract A Neutrophil/TGF-β Axis Limits the Pathogenicity of Allergen-specific CD4+ T Cells] [Synopsis A Neutrophil/TGF-β Axis Limits the Pathogenicity of Allergen-specific CD4+ T Cells] Whitehead GS, Thomas SY, Nakano K, Royer DJ, Burke CG, Nakano H, Cook DN. February 2022

Association of Deepwater Horizon Oil Spill Response and Cleanup Work With Risk of Developing Hypertension [Abstract Association of Deepwater Horizon Oil Spill Response and Cleanup Work With Risk of Developing Hypertension] [Synopsis Association of Deepwater Horizon Oil Spill Response and Cleanup Work With Risk of Developing Hypertension] [Story Association of Deepwater Horizon Oil Spill Response and Cleanup Work With Risk of Developing Hypertension] Kwok RK, Jackson WB 2nd, Curry MD, Stewart PA, McGrath JA, Stenzel M, Huynh TB, Groth CP, Ramachandran G, Banerjee S, Pratt GC, Miller AK, Zhang X, Engel LS, Sandler DP. February 2022

Effect of a Solar Lighting Intervention on Fuel-based Lighting Use and Exposure to Household Air Pollution in Rural Uganda: A Randomized Controlled Trial [Abstract Effect of a Solar Lighting Intervention on Fuel-based Lighting Use and Exposure to Household Air Pollution in Rural Uganda: A Randomized Controlled Trial] [Synopsis Effect of a Solar Lighting Intervention on Fuel-based Lighting Use and Exposure to Household Air Pollution in Rural Uganda: A Randomized Controlled Trial] Wallach ES, Lam NL, Nuwagira E, Muyanja D, Tayebwa M, Valeri L, Tsai AC, Vallarino J, Allen JG, Lai PS. February 2022

Fine Particulate Matter and Lung Function among Burning-exposed Deepwater Horizon Oil Spill Workers [Abstract Fine Particulate Matter and Lung Function among Burning-exposed Deepwater Horizon Oil Spill Workers] [Synopsis Fine Particulate Matter and Lung Function among Burning-exposed Deepwater Horizon Oil Spill Workers] Chen D, Lawrence KG, Pratt GC, Stenzel MR, Stewart PA, Groth CP, Banerjee S, Christenbury K, Curry MD, Jackson WB 2nd, Kwok RK, Blair A, Engel LS, Sandler DP. February 2022

Metals and Risk of Incident Metabolic Syndrome in a Prospective Cohort of Midlife Women in the United States [Abstract Metals and Risk of Incident Metabolic Syndrome in a Prospective Cohort of Midlife Women in the United States] [Synopsis Metals and Risk of Incident Metabolic Syndrome in a Prospective Cohort of Midlife Women in the United States] Wang X, Karvonen-Gutierrez CA, Herman WH, Mukherjee B, Park SK. February 2022

Multimodal Regulatory Elements Within a Hormone-Specific Super Enhancer Control a Heterogeneous Transcriptional Respons [Abstract Multimodal Regulatory Elements Within a Hormone-Specific Super Enhancer Control a Heterogeneous Transcriptional Respons] [Synopsis Multimodal Regulatory Elements Within a Hormone-Specific Super Enhancer Control a Heterogeneous Transcriptional Respons] [Story Multimodal Regulatory Elements Within a Hormone-Specific Super Enhancer Control a Heterogeneous Transcriptional Respons] Hoffman JA, Trotter KW, Day CR, Ward JM, Inoue K, Rodriguez J, Archer TK. February 2022

Prevalence and Income-related Disparities in Thirdhand Smoke Exposure to Children [Abstract Prevalence and Income-related Disparities in Thirdhand Smoke Exposure to Children] [Synopsis Prevalence and Income-related Disparities in Thirdhand Smoke Exposure to Children] Matt GE, Merianos AL, Quintana PJE, Hoh E, Dodder NG, Mahabee-Gittens EM. February 2022

Short-term Tetrabromobisphenol A Exposure Promotes Fibrosis of Human Uterine Fibroid Cells in a 3D Culture System Through TGF-beta Signaling [Abstract Short-term Tetrabromobisphenol A Exposure Promotes Fibrosis of Human Uterine Fibroid Cells in a 3D Culture System Through TGF-beta Signaling] [Synopsis Short-term Tetrabromobisphenol A Exposure Promotes Fibrosis of Human Uterine Fibroid Cells in a 3D Culture System Through TGF-beta Signaling] Liu J, Yu L, Castro L, Yan Y, Clayton NP, Bushel P, Flagler ND, Scappini E, Dixon D. February 2022

Activation of the SARS-CoV-2 NSP14 3'-5' Exoribonuclease by NSP10 and Response to Antiviral Inhibitors [Abstract Activation of the SARS-CoV-2 NSP14 3'-5' Exoribonuclease by NSP10 and Response to Antiviral Inhibitors] [Synopsis Activation of the SARS-CoV-2 NSP14 3'-5' Exoribonuclease by NSP10 and Response to Antiviral Inhibitors] Riccio AA, Sullivan ED, Copeland WC. January 2022

Air Pollution Exposure Disparities Across U.S. Population and Income Groups [Abstract Air Pollution Exposure Disparities Across U.S. Population and Income Groups] [Synopsis Air Pollution Exposure Disparities Across U.S. Population and Income Groups] Jbaily A, Zhou X, Liu J, Lee TH, Kamareddine L, Verguet S, Dominici F. January 2022

Bet v 1 and Other Birch Allergens Are More Resistant to Proteolysis and More Abundant Than Other Birch Pollen Proteins [Abstract Bet v 1 and Other Birch Allergens Are More Resistant to Proteolysis and More Abundant Than Other Birch Pollen Proteins] [Synopsis Bet v 1 and Other Birch Allergens Are More Resistant to Proteolysis and More Abundant Than Other Birch Pollen Proteins] Cabrera A, Foo ACY, Fitzgerald MC, Mueller GA. January 2022

Bipartite Interaction Sites Differentially Modulate RNA-Binding Affinity of a Protein Complex Essential for Germline Stem Cell Self-Renewal [Abstract Bipartite Interaction Sites Differentially Modulate RNA-Binding Affinity of a Protein Complex Essential for Germline Stem Cell Self-Renewal] [Synopsis Bipartite Interaction Sites Differentially Modulate RNA-Binding Affinity of a Protein Complex Essential for Germline Stem Cell Self-Renewal] Qiu C, Wine RN, Campbell ZT, Hall TMT. January 2022

Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro Adipogenic Activity [Abstract Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro Adipogenic Activity] [Synopsis Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro Adipogenic Activity] Herkert NJ, Kassotis CD, Zhang S, Han Y, Pulikkal VF, Sun M, Ferguson PL, Stapleton HM. January 2022

Evaluation of a Semi-Automated Data Extraction Tool for Public Health Literature-Based Reviews: Dextr [Abstract Evaluation of a Semi-Automated Data Extraction Tool for Public Health Literature-Based Reviews: Dextr] [Synopsis Evaluation of a Semi-Automated Data Extraction Tool for Public Health Literature-Based Reviews: Dextr] Walker VR, Schmitt CP, Wolfe MS, Nowak AJ, Kulesza K, Williams AR, Shin R, Cohen J, Burch D, Stout MD, Shipkowski KA, Rooney AA. January 2022

High-throughput Chemical Screening and Structure-based Models to Predict hERG Inhibition [Abstract High-throughput Chemical Screening and Structure-based Models to Predict hERG Inhibition] [Synopsis High-throughput Chemical Screening and Structure-based Models to Predict hERG Inhibition] Krishna S, Borrel A, Huang R, Zhao J, Xia M, Kleinstreuer N. January 2022

Phthalates and Attributable Mortality: A Population-based Longitudinal Cohort Study and Cost Analysis [Abstract Phthalates and Attributable Mortality: A Population-based Longitudinal Cohort Study and Cost Analysis] [Synopsis Phthalates and Attributable Mortality: A Population-based Longitudinal Cohort Study and Cost Analysis] Trasande L, Liu B, Bao W. January 2022

Residential Ultraviolet Radiation and Breast Cancer Risk in a Large Prospective Cohort [Abstract Residential Ultraviolet Radiation and Breast Cancer Risk in a Large Prospective Cohort] [Synopsis Residential Ultraviolet Radiation and Breast Cancer Risk in a Large Prospective Cohort] Gregoire AM, VoPham T, Laden F, Yarosh R, O'Brien KM, Sandler DP, White AJ. January 2022

Toxicity Assessment of 91-day Repeated Inhalation Exposure to an Indoor School Air Mixture of PCBs [Abstract Toxicity Assessment of 91-day Repeated Inhalation Exposure to an Indoor School Air Mixture of PCBs] [Synopsis Toxicity Assessment of 91-day Repeated Inhalation Exposure to an Indoor School Air Mixture of PCBs] Wang H, Adamcakova-Dodd A, Lehmler HJ, Hornbuckle KC, Thorne PS. January 2022

Association of Outdoor Ambient Fine Particulate Matter With Intracellular White Matter Microstructural Properties Among Children [Abstract Association of Outdoor Ambient Fine Particulate Matter With Intracellular White Matter Microstructural Properties Among Children] [Synopsis Association of Outdoor Ambient Fine Particulate Matter With Intracellular White Matter Microstructural Properties Among Children] Burnor E, Cserbik D, Cotter DL, Palmer CE, Ahmadi H, Eckel SP, Berhane K, McConnell R, Chen JC, Schwartz J, Jackson R, Herting MM. December 2021

Cadmium Exposure Modulates the Gut-liver Axis in an Alzheimer's Disease Mouse Model [Abstract Cadmium Exposure Modulates the Gut-liver Axis in an Alzheimer's Disease Mouse Model] [Synopsis Cadmium Exposure Modulates the Gut-liver Axis in an Alzheimer's Disease Mouse Model] Zhang A, Matsushita M, Zhang L, Wang H, Shi X, Gu H, Xia Z, Cui JY. December 2021

Dopamine Neuron Challenge Test for Early Detection of Parkinson's Disease [Abstract Dopamine Neuron Challenge Test for Early Detection of Parkinson's Disease] [Synopsis Dopamine Neuron Challenge Test for Early Detection of Parkinson's Disease] Zhou J, Li J, Papaneri AB, Kobzar NP, Cui G. December 2021

Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mic [Abstract Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mic] [Synopsis Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mic] Sui Y, Meng Z, Chen J, Liu J, Hernandez R, Gonzales MB, Gwag T, Morris AJ, Zhou C. December 2021

Evaluating the Impact of the Clean Heat Program on Air Pollution Levels in New York City [Abstract Evaluating the Impact of the Clean Heat Program on Air Pollution Levels in New York City] [Synopsis Evaluating the Impact of the Clean Heat Program on Air Pollution Levels in New York City] Zhang L, He MZ, Gibson EA, Perera F, Lovasi GS, Clougherty JE, Carrión D, Burke K, Fry D, Kioumourtzoglou MA. December 2021

Greenness, Air Pollution, and Mortality Risk: A U.S. Cohort Study of Cancer Patients and Survivors [Abstract Greenness, Air Pollution, and Mortality Risk: A U.S. Cohort Study of Cancer Patients and Survivors] [Synopsis Greenness, Air Pollution, and Mortality Risk: A U.S. Cohort Study of Cancer Patients and Survivors] Coleman CJ, Yeager RA, Riggs DW, Coleman NC, Garcia GR, Bhatnagar A, Pope CA. December 2021

Longitudinal Exposure to Consumer Product Chemicals and Changes in Plasma Oxylipins in Pregnant Women [Abstract Longitudinal Exposure to Consumer Product Chemicals and Changes in Plasma Oxylipins in Pregnant Women] [Synopsis Longitudinal Exposure to Consumer Product Chemicals and Changes in Plasma Oxylipins in Pregnant Women] Welch BM, Keil AP, Bommarito PA, van T' Erve TJ, Deterding LJ, Williams JG, Lih FB, Cantonwine DE, McElrath TF, Ferguson KK. December 2021

Whole-Body Inhalation Exposure to 2-ethyltoluene for Two Weeks Produced Nasal Lesions in Rats and Mice [Abstract Whole-Body Inhalation Exposure to 2-ethyltoluene for Two Weeks Produced Nasal Lesions in Rats and Mice] [Synopsis Whole-Body Inhalation Exposure to 2-ethyltoluene for Two Weeks Produced Nasal Lesions in Rats and Mice] Huang MC, Willson CJ, Jaligama S, Baker GL, Singer AW, Cao Y, Pierfelice J, Mutlu E, Burback B, Xie G, Malarkey DE, Sparrow B, Ryan K, Stout M, Roberts GK. December 2021

A Post-transcriptional Regulon Controlled by TtpA, the Single Tristetraprolin Family Member Expressed in Dictyostelium Discoideum [Abstract A Post-transcriptional Regulon Controlled by TtpA, the Single Tristetraprolin Family Member Expressed in Dictyostelium Discoideum] [Synopsis A Post-transcriptional Regulon Controlled by TtpA, the Single Tristetraprolin Family Member Expressed in Dictyostelium Discoideum] Bai W, Wells ML, Lai WS, Hicks SN, Burkholder AB, Perera L, Kimmel AR, Blackshear PJ. November 2021

Cord Serum Elementomics Profiling of 56 Elements Depicts Risk of Preterm Birth: Evidence From a Prospective Birth Cohort in Rural Bangladesh [Abstract Cord Serum Elementomics Profiling of 56 Elements Depicts Risk of Preterm Birth: Evidence From a Prospective Birth Cohort in Rural Bangladesh] [Synopsis Cord Serum Elementomics Profiling of 56 Elements Depicts Risk of Preterm Birth: Evidence From a Prospective Birth Cohort in Rural Bangladesh] Huang H, Wei L, Chen X, Zhang R, Su L, Rahman M, Golam Mostofa M, Qamruzzaman Q, Zhao Y, Yu H, Wei Y, Christiani DC, Chen F. November 2021

GADGETS: A Genetic Algorithm For Detecting Epistasis Using Nuclear Families [Abstract GADGETS: A Genetic Algorithm For Detecting Epistasis Using Nuclear Families] [Synopsis GADGETS: A Genetic Algorithm For Detecting Epistasis Using Nuclear Families] Nodzenski M, Shi M, Krahn JM, Wise AS, Li Y, Li L, Umbach DM, Weinberg CR. November 2021

Longitudinal Assessment of Kidney Function in Migrant Farm Workers [Abstract Longitudinal Assessment of Kidney Function in Migrant Farm Workers] [Synopsis Longitudinal Assessment of Kidney Function in Migrant Farm Workers] Lopez-Galvez N, Wagoner R, Canales RA, Ernst K, Burgess JL, de Zapien J, Rosales C, Beamer P. November 2021

Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-based Study [Abstract Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-based Study] [Synopsis Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-based Study] van den Dries MA, Keil AP, Tiemeier H, Pronk A, Spaan S, Santos S, Asimakopoulos AG, Kannan K, Gaillard R, Guxens M, Trasande L, Jaddoe VWV, Ferguson KK. November 2021

sEH Promotes Macrophage Phagocytosis and Lung Clearance of Streptococcus Pneumoniae [Abstract sEH Promotes Macrophage Phagocytosis and Lung Clearance of Streptococcus Pneumoniae] [Synopsis sEH Promotes Macrophage Phagocytosis and Lung Clearance of Streptococcus Pneumoniae] [Story sEH Promotes Macrophage Phagocytosis and Lung Clearance of Streptococcus Pneumoniae] Li H, Bradbury JA, Edin ML, Graves JP, Gruzdev A, Cheng J, Hoopes SL, DeGraff LM, Fessler MB, Garantziotis S, Schurman SH, Zeldin DC. November 2021

Sex-specific Relationships of the Infant Microbiome and Early-childhood Behavioral Outcomes [Abstract Sex-specific Relationships of the Infant Microbiome and Early-childhood Behavioral Outcomes] [Synopsis Sex-specific Relationships of the Infant Microbiome and Early-childhood Behavioral Outcomes] Bai W, Wells ML, Lai WS, Hicks SN, Burkholder AB, Perera L, Kimmel AR, Blackshear PJ. November 2021

Characterizing the Chemical Landscape in Commercial E-cigarette Liquids and Aerosols by Liquid Chromatography-high-resolution Mass Spectrometry [Abstract Characterizing the Chemical Landscape in Commercial E-cigarette Liquids and Aerosols by Liquid Chromatography-high-resolution Mass Spectrometry] [Synopsis Characterizing the Chemical Landscape in Commercial E-cigarette Liquids and Aerosols by Liquid Chromatography-high-resolution Mass Spectrometry] Tehrani MW, Newmeyer MN, Rule AM, Prasse C. October 2021

Cobalt-Induced Oxidative Stress Contributes to Alveolar/Bronchiolar Carcinogenesis in B6C3F1/N Mice [Abstract Cobalt-Induced Oxidative Stress Contributes to Alveolar/Bronchiolar Carcinogenesis in B6C3F1/N Mice] [Synopsis Cobalt-Induced Oxidative Stress Contributes to Alveolar/Bronchiolar Carcinogenesis in B6C3F1/N Mice] Ton TT, Kovi RC, Peddada TN, Chhabria RM, Shockley KR, Flagler ND, Gerrish KE, Herbert RA, Behl M, Hoenerhoff MJ, Sills RC, Pandiri AR. October 2021

CometChip Analysis of Human Primary Lymphocytes Enables Quantification of Inter-individual Differences in the Kinetics of Repair of Oxidative DNA Damage [Abstract CometChip Analysis of Human Primary Lymphocytes Enables Quantification of Inter-individual Differences in the Kinetics of Repair of Oxidative DNA Damage] [Synopsis CometChip Analysis of Human Primary Lymphocytes Enables Quantification of Inter-individual Differences in the Kinetics of Repair of Oxidative DNA Damage] Ngo LP, Kaushal S, Chaim IA, Mazzucato P, Ricciardi C, Samson LD, Nagel ZD, Engelward BP. October 2021

Differential Signalling Induced by alpha7 Nicotinic Acetylcholine Receptors in Hippocampal Dentate Gyrus in Vitro and in Vivo [Abstract Differential Signalling Induced by alpha7 Nicotinic Acetylcholine Receptors in Hippocampal Dentate Gyrus in Vitro and in Vivo] [Synopsis Differential Signalling Induced by alpha7 Nicotinic Acetylcholine Receptors in Hippocampal Dentate Gyrus in Vitro and in Vivo] Cheng Q, Lamb P, Stevanovic K, Bernstein BJ, Fry SA, Cushman JD, Yakel JL. October 2021

Foliar Surfaces As Dust and Aerosol Pollution Monitors: An Assessment by a Mining Site [Abstract Foliar Surfaces As Dust and Aerosol Pollution Monitors: An Assessment by a Mining Site] [Synopsis Foliar Surfaces As Dust and Aerosol Pollution Monitors: An Assessment by a Mining Site] Zeider K, Van Overmeiren N, Rine KP, Sandhaus S, Sáez AE, Sorooshian A, Muñoz HC, Ramírez-Andreotta MD. October 2021

High-Coverage Metabolomics Uncovers Microbiota-Driven Biochemical Landscape of Interorgan Transport and Gut-Brain Communication in Mice [Abstract High-Coverage Metabolomics Uncovers Microbiota-Driven Biochemical Landscape of Interorgan Transport and Gut-Brain Communication in Mice] [Synopsis High-Coverage Metabolomics Uncovers Microbiota-Driven Biochemical Landscape of Interorgan Transport and Gut-Brain Communication in Mice] Lai Y, Liu CW, Yang Y, Hsiao YC, Ru H, Lu K. October 2021

Latent, Sex-specific Metabolic Health Effects in CD-1 Mouse Offspring Exposed to PFOA or HFPO-DA (GenX) During Gestation [Abstract Latent, Sex-specific Metabolic Health Effects in CD-1 Mouse Offspring Exposed to PFOA or HFPO-DA (GenX) During Gestation] [Synopsis Latent, Sex-specific Metabolic Health Effects in CD-1 Mouse Offspring Exposed to PFOA or HFPO-DA (GenX) During Gestation] Cope HA, Blake BE, Love C, McCord J, Elmore SA, Harvey JB, Chappell VA, Fenton SE. October 2021

Mental Health Indicators and Lung Function Following a Large Oil Spill [Abstract Mental Health Indicators and Lung Function Following a Large Oil Spill] [Synopsis Mental Health Indicators and Lung Function Following a Large Oil Spill] Lawrence KG, Werder EJ, Kwok RK, Engel LS, Sandler DP. October 2021

Paternal Preconception Phthalate Exposure Alters Sperm Methylome and Embryonic Programming [Abstract Paternal Preconception Phthalate Exposure Alters Sperm Methylome and Embryonic Programming] [Synopsis Paternal Preconception Phthalate Exposure Alters Sperm Methylome and Embryonic Programming] Oluwayiose OA, Marcho C, Wu H, Houle E, Krawetz SA, Suvorov A, Mager J, Richard Pilsner J. October 2021

The Limits of Small-For-Gestational-Age As a High-Risk Category [Abstract The Limits of Small-For-Gestational-Age As a High-Risk Category] [Synopsis The Limits of Small-For-Gestational-Age As a High-Risk Category] Wilcox AJ, Cortese M, McConnaughey DR, Moster D, Basso O. October 2021

Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancer [Abstract Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancer] [Synopsis Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancer] Kim JI, Fine JP, Sandler DP, Zhao S. September 2021

A Scalable Workflow to Characterize the Human Exposome [Abstract A Scalable Workflow to Characterize the Human Exposome] [Synopsis A Scalable Workflow to Characterize the Human Exposome] Hu X, Walker DI, Liang Y, Smith MR, Orr ML, Juran BD, Ma C, Uppal K, Koval M, Martin GS, Neujahr DC, Marsit CJ, Go YM, Pennell KD, Miller GW, Lazaridis KN, Jones DP. September 2021

Characterization of SARS2 Nsp15 Nuclease Activity Reveals It's Mad About U [Abstract Characterization of SARS2 Nsp15 Nuclease Activity Reveals It's Mad About U] [Synopsis Characterization of SARS2 Nsp15 Nuclease Activity Reveals It's Mad About U] Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE. September 2021

Proteogenomic Characterization of Pancreatic Ductal Adenocarcinoma [Abstract Proteogenomic Characterization of Pancreatic Ductal Adenocarcinoma] [Synopsis Proteogenomic Characterization of Pancreatic Ductal Adenocarcinoma] Cao L, Huang C, Cui Zhou D, Hu Y, Lih TM, Savage SR, Krug K, Clark DJ, Schnaubelt M, Chen L, da Veiga Leprevost F, Eguez RV, Yang W, Pan J, Wen B, Dou Y, Jiang W, Liao Y, Shi Z, Terekhanova NV, Cao S, Lu RJ, Li Y, Liu R, Zhu H, Ronning P, Wu Y, Wyczalkowski MA, Easwaran H, Danilova L, Mer AS, Yoo S, Wang JM, Liu W, Haibe-Kains B, Thiagarajan M, Jewell SD, Hostetter G, Newton CJ, Li QK, Roehrl MH, Fenyö D, Wang P, Nesvizhskii AI, Mani DR, Omenn GS, Boja ES, Mesri M, Robles AI, Rodriguez H, Bathe OF, Chan DW, Hruban RH, Ding L, Zhang B, Zhang H; Clinical Proteomic Tumor Analysis Consortium. September 2021

Topical Hypochlorous Acid (HOCl) Blocks Inflammatory Gene Expression and Tumorigenic Progression in UV-exposed SKH-1 High Risk Mouse Skin [Abstract Topical Hypochlorous Acid (HOCl) Blocks Inflammatory Gene Expression and Tumorigenic Progression in UV-exposed SKH-1 High Risk Mouse Skin] [Synopsis Topical Hypochlorous Acid (HOCl) Blocks Inflammatory Gene Expression and Tumorigenic Progression in UV-exposed SKH-1 High Risk Mouse Skin] Lawrence KG, Werder EJ, Sandler DP. September 2021

A Prospective Study of Maternal 25-Hydroxyvitamin D (25OHD) in the First Trimester of Pregnancy and Second Trimester Heavy Metal Levels [Abstract A Prospective Study of Maternal 25-Hydroxyvitamin D (25OHD) in the First Trimester of Pregnancy and Second Trimester Heavy Metal Levels] [Synopsis A Prospective Study of Maternal 25-Hydroxyvitamin D (25OHD) in the First Trimester of Pregnancy and Second Trimester Heavy Metal Levels] Jukic AMZ, Kim SS, Meeker JD, Weiss ST, Cantonwine DE, McElrath TF, Ferguson KK. August 2021

Catalyzing Knowledge-driven Discovery in Environmental Health Sciences Through a Community-driven Harmonized Language [Abstract Catalyzing Knowledge-driven Discovery in Environmental Health Sciences Through a Community-driven Harmonized Language] [Synopsis Catalyzing Knowledge-driven Discovery in Environmental Health Sciences Through a Community-driven Harmonized Language] Holmgren SD, Boyles RR, Cronk RD, Duncan CG, Kwok RK, Lunn RM, Osborn KC, Thessen AE, Schmitt CP. August 2021

CD11b+ Lung Dendritic Cells at Different Stages of Maturation Induce Th17 or Th2 Differentiation [Abstract CD11b+ Lung Dendritic Cells at Different Stages of Maturation Induce Th17 or Th2 Differentiation] [Synopsis CD11b+ Lung Dendritic Cells at Different Stages of Maturation Induce Th17 or Th2 Differentiation] Izumi G, Nakano H, Nakano K, Whitehead GS, Grimm SA, Fessler MB, Karmaus PW, Cook DN. August 2021

Chlorine Inhalation Induces Acute Chest Syndrome in Humanized Sickle Cell Mouse Model and Ameliorated by Postexposure Hemopexin [Abstract Chlorine Inhalation Induces Acute Chest Syndrome in Humanized Sickle Cell Mouse Model and Ameliorated by Postexposure Hemopexin] [Synopsis Chlorine Inhalation Induces Acute Chest Syndrome in Humanized Sickle Cell Mouse Model and Ameliorated by Postexposure Hemopexin] Alishlash AS, Sapkota M, Ahmad I, Maclin K, Ahmed NA, Molyvdas A, Doran S, Albert CJ, Aggarwal S, Ford DA, Ambalavanan N, Jilling T, Matalon S. August 2021

Constitutive Expression of Steroidogenic Factor-1 (NR5A1) Disrupts Ovarian Functions, Fertility, and Metabolic Homeostasis in Female Mice [Abstract Constitutive Expression of Steroidogenic Factor-1 (NR5A1) Disrupts Ovarian Functions, Fertility, and Metabolic Homeostasis in Female Mice] [Synopsis Constitutive Expression of Steroidogenic Factor-1 (NR5A1) Disrupts Ovarian Functions, Fertility, and Metabolic Homeostasis in Female Mice] Rotgers E, Nicol B, Rodriguez K, Rattan S, Flaws JA, Yao HH. August 2021

Excess of COVID-19 Cases and Deaths Due to Fine Particulate Matter Exposure During the 2020 Wildfires in the United States [Abstract Excess of COVID-19 Cases and Deaths Due to Fine Particulate Matter Exposure During the 2020 Wildfires in the United States] [Synopsis Excess of COVID-19 Cases and Deaths Due to Fine Particulate Matter Exposure During the 2020 Wildfires in the United States] Zhou X, Josey K, Kamareddine L, Caine MC, Liu T, Mickley LJ, Cooper M, Dominici F. August 2021

GLIS1 Regulates Trabecular Meshwork Function and Intraocular Pressure and Is Associated With Glaucoma in Humans [Abstract GLIS1 Regulates Trabecular Meshwork Function and Intraocular Pressure and Is Associated With Glaucoma in Humans] [Synopsis GLIS1 Regulates Trabecular Meshwork Function and Intraocular Pressure and Is Associated With Glaucoma in Humans] Nair KS, Srivastava C, Brown RV, Koli S, Choquet H, Kang HS, Kuo YM, Grimm SA, Sutherland C, Badea A, Johnson GA, Zhao Y, Yin J, Okamoto K, Clark G, Borras T, Zode G, Kizhatil K, Chakrabarti S, John SWM, Jorgenson E, Jetten AM. August 2021

Randomized Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health: Results of the CLEAN AIR STUDY [Abstract Randomized Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health: Results of the CLEAN AIR STUDY] [Synopsis Randomized Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health: Results of the CLEAN AIR STUDY] Hansel NN, Putcha N, Woo H, Peng R, Diette GB, Fawzy A, Wise RA, Romero K, Davis MF, Rule AM, Eakin MN, Breysse PN, McCormack MC, Koehler K. August 2021

Up-regulation of the Manganese Transporter SLC30A10 by Hypoxia-inducible Factors Defines a Homeostatic Response to Manganese Toxicity [Abstract Up-regulation of the Manganese Transporter SLC30A10 by Hypoxia-inducible Factors Defines a Homeostatic Response to Manganese Toxicity] [Synopsis Up-regulation of the Manganese Transporter SLC30A10 by Hypoxia-inducible Factors Defines a Homeostatic Response to Manganese Toxicity] Liu C, Jursa T, Aschner M, Smith DR, Mukhopadhyay S. August 2021

Whole Genome Sequencing of Low Input Circulating Cell-free DNA Obtained From Normal Human Subjects [Abstract Whole Genome Sequencing of Low Input Circulating Cell-free DNA Obtained From Normal Human Subjects] [Synopsis Whole Genome Sequencing of Low Input Circulating Cell-free DNA Obtained From Normal Human Subjects] Foley JF, Elgart B, Alex Merrick B, Phadke DP, Cook ME, Malphurs JA, Solomon GG, Shah RR, Fessler MB, Miller FW, Gerrish KE. August 2021

Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors [Abstract Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors] [Synopsis Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors] Cardona B, Rudel RA. July 2021

Association of Neighborhood Deprivation With Pulmonary Function Measures Among Participants in the Gulf Long-Term Follow-up Study [Abstract Association of Neighborhood Deprivation With Pulmonary Function Measures Among Participants in the Gulf Long-Term Follow-up Study] [Synopsis Association of Neighborhood Deprivation With Pulmonary Function Measures Among Participants in the Gulf Long-Term Follow-up Study] Lawrence KG, Werder EJ, Sandler DP. July 2021

Experiences With Everyday and Major Forms of Racial/Ethnic Discrimination and Type 2 Diabetes Risk Among White, Black, and Hispanic/Latina Women: Findings From the Sister Study [Abstract Experiences With Everyday and Major Forms of Racial/Ethnic Discrimination and Type 2 Diabetes Risk Among White, Black, and Hispanic/Latina Women: Findings From the Sister Study] [Synopsis Experiences With Everyday and Major Forms of Racial/Ethnic Discrimination and Type 2 Diabetes Risk Among White, Black, and Hispanic/Latina Women: Findings From the Sister Study] Gaston SA, Atere-Roberts J, Ward J, Slopen NB, Forde AT, Sandler DP, Williams DR, Jackson CL. July 2021

Exposure To E-cigarette Aerosol Over Two Months Induces Accumulation of Neurotoxic Metals and Alteration of Essential Metals in Mouse Brain [Abstract Exposure To E-cigarette Aerosol Over Two Months Induces Accumulation of Neurotoxic Metals and Alteration of Essential Metals in Mouse Brain] [Synopsis Exposure To E-cigarette Aerosol Over Two Months Induces Accumulation of Neurotoxic Metals and Alteration of Essential Metals in Mouse Brain] Re DB, Hilpert M, Saglimbeni B, Strait M, Ilievski V, Coady M, Talayero M, Wilmsen K, Chesnais H, Balac O, Glabonjat RA, Slavkovich V, Yan B, Graziano J, Navas-Acien A, Kleiman NJ. July 2021

INO80 Promotes H2A.Z Occupancy to Regulate Cell Fate Transition in Pluripotent Stem Cells [Abstract INO80 Promotes H2A.Z Occupancy to Regulate Cell Fate Transition in Pluripotent Stem Cells] [Synopsis INO80 Promotes H2A.Z Occupancy to Regulate Cell Fate Transition in Pluripotent Stem Cells] Yu H, Wang J, Lackford B, Bennett B, Li JL, Hu G. July 2021

Isoflavone Diet Ameliorates Experimental Autoimmune Encephalomyelitis Through Modulation of Gut Bacteria Depleted in Patients With Multiple Sclerosis [Abstract Isoflavone Diet Ameliorates Experimental Autoimmune Encephalomyelitis Through Modulation of Gut Bacteria Depleted in Patients With Multiple Sclerosis] [Synopsis Isoflavone Diet Ameliorates Experimental Autoimmune Encephalomyelitis Through Modulation of Gut Bacteria Depleted in Patients With Multiple Sclerosis] Jensen SN, Cady NM, Shahi SK, Peterson SR, Gupta A, Gibson-Corley KN, Mangalam AK. July 2021

Effects of Buprenorphine, Chlorhexidine, and Low-level Laser Therapy on Wound Healing in Mice [Abstract Effects of Buprenorphine, Chlorhexidine, and Low-level Laser Therapy on Wound Healing in Mice] [Synopsis Effects of Buprenorphine, Chlorhexidine, and Low-level Laser Therapy on Wound Healing in Mice] Webb DR, Churchill SR, Hill GD, McGee CA, Shi M, King-Herbert AP, Blankenship-Paris TL. June 2021

Impact of Ambient Temperature on Ovarian Reserve [Abstract Impact of Ambient Temperature on Ovarian Reserve] [Synopsis Impact of Ambient Temperature on Ovarian Reserve] Gaskins AJ, Minguez-Alarcon L, VoPham T, Hart JE, Chavarro JE, Schwartz J, Souter I, Laden F. June 2021

Mammary Cell Gene Expression Atlas Links Epithelial Cell Remodeling Events to Breast Carcinogenesis [Abstract Mammary Cell Gene Expression Atlas Links Epithelial Cell Remodeling Events to Breast Carcinogenesis] [Synopsis Mammary Cell Gene Expression Atlas Links Epithelial Cell Remodeling Events to Breast Carcinogenesis] Saeki K, Chang G, Kanaya N, Wu X, Wang J, Bernal L, Ha D, Neuhausen SL, Chen S. June 2021

Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation [Abstract Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation] [Synopsis Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation] Busada JT, Peterson KN, Khadka S, Xu X, Oakley RH, Cook DN, Cidlowski JA. May 2021

Longitudinal Investigation of Pubertal Milestones and Hormones As a Function of Body Fat in Girls [Abstract Longitudinal Investigation of Pubertal Milestones and Hormones As a Function of Body Fat in Girls] [Synopsis Longitudinal Investigation of Pubertal Milestones and Hormones As a Function of Body Fat in Girls] [Story Longitudinal Investigation of Pubertal Milestones and Hormones As a Function of Body Fat in Girls] Ortega MT, McGrath JA, Carlson L, Flores Poccia V, Larson G, Douglas C, Sun BZ, Zhao S, Beery B, Vesper HW, Duke L, Botelho JC, Filie AC, Shaw ND. May 2021

Prenatal Exposure to Glyphosate and Its Environmental Degradate, Aminomethylphosphonic Acid (AMPA), and Preterm Birth: A Nested Case-Control Study in the PROTECT Cohort (Puerto Rico) [Abstract Prenatal Exposure to Glyphosate and Its Environmental Degradate, Aminomethylphosphonic Acid (AMPA), and Preterm Birth: A Nested Case-Control Study in the PROTECT Cohort (Puerto Rico)] [Synopsis Prenatal Exposure to Glyphosate and Its Environmental Degradate, Aminomethylphosphonic Acid (AMPA), and Preterm Birth: A Nested Case-Control Study in the PROTECT Cohort (Puerto Rico)] Silver MK, Fernandez J, Tang J, McDade A, Sabino J, Rosario Z, Vélez Vega C, Alshawabkeh A, Cordero JF, Meeker JD. May 2021

SIRT1 Regulates Sphingolipid Metabolism and Neural Differentiation of Mouse Embryonic Stem Cells Through c-Myc-SMPDL3B [Abstract SIRT1 Regulates Sphingolipid Metabolism and Neural Differentiation of Mouse Embryonic Stem Cells Through c-Myc-SMPDL3B] [Synopsis SIRT1 Regulates Sphingolipid Metabolism and Neural Differentiation of Mouse Embryonic Stem Cells Through c-Myc-SMPDL3B] Fan W, Tang S, Fan X, Fang Y, Xu X, Li L, Xu J, Li JL, Wang Z, Li X. May 2021

The Aryl Hydrocarbon Receptor Suppresses Immunity To Oral Squamous Cell Carcinoma Through Immune Checkpoint Regulation [Abstract The Aryl Hydrocarbon Receptor Suppresses Immunity To Oral Squamous Cell Carcinoma Through Immune Checkpoint Regulation] [Synopsis The Aryl Hydrocarbon Receptor Suppresses Immunity To Oral Squamous Cell Carcinoma Through Immune Checkpoint Regulation] Kenison JE, Wang Z, Yang K, Snyder M, Quintana FJ, Sherr DH. May 2021

The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry [Abstract The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry] [Synopsis The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry] Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. May 2021

Toxicokinetic Evaluation of the Common Indoor Air Pollutant, Alpha-pinene, and Its Potential Reactive Metabolite, Alpha-pinene Oxide, Following Inhalation Exposure in Rodents [Abstract Toxicokinetic Evaluation of the Common Indoor Air Pollutant, Alpha-pinene, and Its Potential Reactive Metabolite, Alpha-pinene Oxide, Following Inhalation Exposure in Rodents] [Synopsis Toxicokinetic Evaluation of the Common Indoor Air Pollutant, Alpha-pinene, and Its Potential Reactive Metabolite, Alpha-pinene Oxide, Following Inhalation Exposure in Rodents] Waidyanatha S, Hackett M, Black SR, Stout MD, Fennell TR, Silinski MR, Watson SL, Licause J, Robinson VG, Sparrow B, Fernando RA, Cooper S, Rider CV. May 2021

Autophagy of the M6A mRNA Demethylase FTO Is Impaired by Low-level Arsenic Exposure to Promote Tumorigenesis [Abstract Autophagy of the M6A mRNA Demethylase FTO Is Impaired by Low-level Arsenic Exposure to Promote Tumorigenesis] [Synopsis Autophagy of the M6A mRNA Demethylase FTO Is Impaired by Low-level Arsenic Exposure to Promote Tumorigenesis] Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. April 2021

Developmental Exposures to Perfluorooctanesulfonic Acid (PFOS) Impact Embryonic Nutrition, Pancreatic Morphology, and Adiposity in the Zebrafish, Danio Rerio [Abstract Developmental Exposures to Perfluorooctanesulfonic Acid (PFOS) Impact Embryonic Nutrition, Pancreatic Morphology, and Adiposity in the Zebrafish, Danio Rerio] [Synopsis Developmental Exposures to Perfluorooctanesulfonic Acid (PFOS) Impact Embryonic Nutrition, Pancreatic Morphology, and Adiposity in the Zebrafish, Danio Rerio] Sant KE, Annunziato K, Conlin S, Teicher G, Chen P, Venezia O, Downes GB, Park Y, Timme-Laragy AR. April 2021

Inhalation of Two Prop 65-listed Chemicals Within Vehicles May Be Associated With Increased Cancer Risk [Abstract Inhalation of Two Prop 65-listed Chemicals Within Vehicles May Be Associated With Increased Cancer Risk] [Synopsis Inhalation of Two Prop 65-listed Chemicals Within Vehicles May Be Associated With Increased Cancer Risk] Reddam A, Volz DC. April 2021

Prenatal Phthalate Exposures and Executive Function in Preschool Children [Abstract Prenatal Phthalate Exposures and Executive Function in Preschool Children] [Synopsis Prenatal Phthalate Exposures and Executive Function in Preschool Children] Choi G, Villanger GD, Drover SSM, Sakhi AK, Thomsen C, Nethery RC, Zeiner P, Knudsen GP, Reichborn-Kjennerud T, Overgaard KR, Herring AH, Skogan AH, Biele G, Aase H, Engel SM. April 2021

SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19 [Abstract SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19] [Synopsis SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19] Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, Chen PY, Nakamura K, Whitman JD, Hanson PJ, McManus BM, Ott M, Conklin BR, McDevitt TC. April 2021

UDP-Glucose and P2Y14 Receptor Amplify Allergen-Induced Airway Eosinophilia [Abstract UDP-Glucose and P2Y14 Receptor Amplify Allergen-Induced Airway Eosinophilia] [Synopsis UDP-Glucose and P2Y14 Receptor Amplify Allergen-Induced Airway Eosinophilia] [Story UDP-Glucose and P2Y14 Receptor Amplify Allergen-Induced Airway Eosinophilia] Karcz TP, Whitehead GS, Nakano K, Nakano H, Grimm SA, Williams JG, Deterding LJ, Jacobson KA, Cook DN. April 2021

Urine Tungsten and Chronic Kidney Disease in Rural Colorado [Abstract Urine Tungsten and Chronic Kidney Disease in Rural Colorado] [Synopsis Urine Tungsten and Chronic Kidney Disease in Rural Colorado] Fox J, Macaluso F, Moore C, Mesenbring E, Johnson RJ, Hamman RF, James KA. April 2021

Watching a Double Strand Break Repair Polymerase Insert a Pro-Mutagenic Oxidized Nucleotide [Abstract Watching a Double Strand Break Repair Polymerase Insert a Pro-Mutagenic Oxidized Nucleotide] [Synopsis Watching a Double Strand Break Repair Polymerase Insert a Pro-Mutagenic Oxidized Nucleotide] Jamsen JA, Sassa A, Shock DD, Beard WA, Wilson SH. April 2021

Air Pollution and Breast Cancer Risk in the Black Women's Health Study [Abstract Air Pollution and Breast Cancer Risk in the Black Women's Health Study] [Synopsis Air Pollution and Breast Cancer Risk in the Black Women's Health Study] White AJ, Gregoire AM, Niehoff NM, Bertrand KA, Palmer JR, Coogan PF, Bethea TN. March 2021

Benchmark Concentrations for Untargeted Metabolomics vs. Transcriptomics for Liver Injury Compounds in in Vitro Liver Models [Abstract Benchmark Concentrations for Untargeted Metabolomics vs. Transcriptomics for Liver Injury Compounds in in Vitro Liver Models] [Synopsis Benchmark Concentrations for Untargeted Metabolomics vs. Transcriptomics for Liver Injury Compounds in in Vitro Liver Models] Crizer DM, Ramaiahgari SC, Ferguson SS, Rice JR, Dunlap PE, Sipes NS, Auerbach SS, Merrick BA, DeVito MJ. March 2021

Citrullinated Vimentin Mediates Development and Progression of Lung Fibrosis [Abstract Citrullinated Vimentin Mediates Development and Progression of Lung Fibrosis] [Synopsis Citrullinated Vimentin Mediates Development and Progression of Lung Fibrosis] Li FJ, Surolia R, Li H, Wang Z, Liu G, Kulkarni T, Massicano AVF, Mobley JA, Mondal S, de Andrade JA, Coonrod SA, Thompson PR, Wille K, Lapi SE, Athar M, Thannickal VJ, Carter AB, Antony VB. March 2021

Excision of Mutagenic Replication-Blocking Lesions Suppresses Cancer but Promotes Cytotoxicity and Lethality in Nitrosamine-Exposed Mice [Abstract Excision of Mutagenic Replication-Blocking Lesions Suppresses Cancer but Promotes Cytotoxicity and Lethality in Nitrosamine-Exposed Mice] [Synopsis Excision of Mutagenic Replication-Blocking Lesions Suppresses Cancer but Promotes Cytotoxicity and Lethality in Nitrosamine-Exposed Mice] Kay JE, Corrigan JJ, Armijo AL, Nazari IS, Kohale IN, Torous DK, Avlasevich SL, Croy RG, Wadduwage DN, Carrasco SE, Dertinger SD, White FM, Essigmann JM, Samson LD, Engelward BP. March 2021

IRGM1 Links Mitochondrial Quality Control to Autoimmunity [Abstract IRGM1 Links Mitochondrial Quality Control to Autoimmunity] [Synopsis IRGM1 Links Mitochondrial Quality Control to Autoimmunity] [Story IRGM1 Links Mitochondrial Quality Control to Autoimmunity] Rai P, Janardhan KS, Meacham J, Madenspacher JH, Lin WC, Karmaus PWF, Martinez J, Li QZ, Yan M, Zeng J, Grinstaff MW, Shirihai OS, Taylor GA, Fessler MB. March 2021

Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine [Abstract Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine] [Synopsis Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine] Ruyle BJ, Pickard HM, LeBlanc DR, Tokranov AK, Thackray CP, Hu XC, Vecitis CD, Sunderland EM. March 2021

Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine [Abstract Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine] [Synopsis Isolating the AFFF Signature in Coastal Watersheds Using Oxidizable PFAS Precursors and Unexplained Organofluorine] Ruyle BJ, Pickard HM, LeBlanc DR, Tokranov AK, Thackray CP, Hu XC, Vecitis CD, Sunderland EM. March 2021

Metabolic Supervision by PPIP5K, an Inositol Pyrophosphate Kinase/Phosphatase, Controls Proliferation of the HCT116 Tumor Cell Line [Abstract Metabolic Supervision by PPIP5K, an Inositol Pyrophosphate Kinase/Phosphatase, Controls Proliferation of the HCT116 Tumor Cell Line] [Synopsis Metabolic Supervision by PPIP5K, an Inositol Pyrophosphate Kinase/Phosphatase, Controls Proliferation of the HCT116 Tumor Cell Line] Gu C, Liu J, Liu X, Zhang H, Luo J, Wang H, Locasale JW, Shears SB. March 2021

Progesterone Receptor Isoform B Regulates the Oxtr-Plcl2-Trpc3 Pathway to Suppress Uterine Contractility [Abstract Progesterone Receptor Isoform B Regulates the Oxtr-Plcl2-Trpc3 Pathway to Suppress Uterine Contractility] [Synopsis Progesterone Receptor Isoform B Regulates the Oxtr-Plcl2-Trpc3 Pathway to Suppress Uterine Contractility] [Story Progesterone Receptor Isoform B Regulates the Oxtr-Plcl2-Trpc3 Pathway to Suppress Uterine Contractility] Peavey MC, Wu SP, Li R, Liu J, Emery OM, Wang T, Zhou L, Wetendorf M, Yallampalli C, Gibbons WE, Lydon JP, DeMayo FJ. March 2021

The Mosquito Protein AEG12 Displays Both Cytolytic and Antiviral Properties Via a Common Lipid Transfer Mechanism [Abstract The Mosquito Protein AEG12 Displays Both Cytolytic and Antiviral Properties Via a Common Lipid Transfer Mechanism] [Synopsis The Mosquito Protein AEG12 Displays Both Cytolytic and Antiviral Properties Via a Common Lipid Transfer Mechanism] [Story The Mosquito Protein AEG12 Displays Both Cytolytic and Antiviral Properties Via a Common Lipid Transfer Mechanism] Foo ACY, Thompson PM, Chen SH, Jadi R, Lupo B, DeRose EF, Arora S, Placentra VC, Premkumar L, Perera L, Pedersen LC, Martin N, Mueller GA. March 2021

Tropical Cyclone Exposure is Associated With Increased Hospitalization Rates in Older Adults [Abstract Tropical Cyclone Exposure is Associated With Increased Hospitalization Rates in Older Adults] [Synopsis Tropical Cyclone Exposure is Associated With Increased Hospitalization Rates in Older Adults] Parks RM, Anderson GB, Nethery RC, Navas-Acien A, Dominici F, Kioumourtzoglou MA. March 2021

Acetylene-Fueled Trichloroethene Reductive Dechlorination in a Groundwater Enrichment Culture [Abstract Acetylene-Fueled Trichloroethene Reductive Dechlorination in a Groundwater Enrichment Culture] [Synopsis Acetylene-Fueled Trichloroethene Reductive Dechlorination in a Groundwater Enrichment Culture] Gushgari-Doyle S, Oremland RS, Keren R, Baesman SM, Akob DM, Banfield JF, Alvarez-Cohen L. February 2021

A Tiered Approach To Prioritizing Registered Pesticides For Potential Cancer Hazard Evaluations: Implications For Decision Making [Abstract A Tiered Approach To Prioritizing Registered Pesticides For Potential Cancer Hazard Evaluations: Implications For Decision Making] [Synopsis A Tiered Approach To Prioritizing Registered Pesticides For Potential Cancer Hazard Evaluations: Implications For Decision Making] Schwingl PJ, Lunn RM, Mehta SS. February 2021

Comparison of Sulfolane Effects in Sprague Dawley rats, B6C3F1/N Mice, and Hartley Guinea Pigs After 28 Days of Exposure Via Oral Gavage [Abstract Comparison of Sulfolane Effects in Sprague Dawley rats, B6C3F1/N Mice, and Hartley Guinea Pigs After 28 Days of Exposure Via Oral Gavage] [Synopsis Comparison of Sulfolane Effects in Sprague Dawley rats, B6C3F1/N Mice, and Hartley Guinea Pigs After 28 Days of Exposure Via Oral Gavage] Shipkowski KA, Cora MC, Cesta MF, Robinson VG, Waidyanatha S, Witt KL, Vallant MK, Fallacara DM, Hejtmancik MR, Masten SA, Cooper SD, Fernando RA, Blystone CR. February 2021

Gestational and Childhood Exposure to Per- and Polyfluoroalkyl Substances and Cardiometabolic Risk at Age 12 Years [Abstract Gestational and Childhood Exposure to Per- and Polyfluoroalkyl Substances and Cardiometabolic Risk at Age 12 Years] [Synopsis Gestational and Childhood Exposure to Per- and Polyfluoroalkyl Substances and Cardiometabolic Risk at Age 12 Years] Li N, Liu Y, Papandonatos GD, Calafat AM, Eaton CB, Kelsey KT, Cecil KM, Kalkwarf HJ, Yolton K, Lanphear BP, Chen A, Braun JM. February 2021

Integrated Analysis of Behavioral, Epigenetic, and Gut Microbiome Analyses in App NL-G-F, App NL-F, and Wild Type Mice [Abstract Integrated Analysis of Behavioral, Epigenetic, and Gut Microbiome Analyses in App NL-G-F, App NL-F, and Wild Type Mice] [Synopsis Integrated Analysis of Behavioral, Epigenetic, and Gut Microbiome Analyses in App NL-G-F, App NL-F, and Wild Type Mice] Kundu P, Torres ERS, Stagaman K, Kasschau K, Okhovat M, Holden S, Ward S, Nevonen KA, Davis BA, Saito T, Saido TC, Carbone L, Sharpton TJ, Raber J. February 2021

LIG1 Syndrome Mutations Remodel a Cooperative Network of Ligand Binding Interactions to Compromise Ligation Efficiency [Abstract LIG1 Syndrome Mutations Remodel a Cooperative Network of Ligand Binding Interactions to Compromise Ligation Efficiency] [Synopsis LIG1 Syndrome Mutations Remodel a Cooperative Network of Ligand Binding Interactions to Compromise Ligation Efficiency] Jurkiw TJ, Tumbale PP, Schellenberg MJ, Cunningham-Rundles C, Williams RS, O'Brien PJ. February 2021

Oral Deoxynivalenol Toxicity in Harlan Sprague Dawley (Hsd:Sprague Dawley® SD®) Rat Dams and Their Offspring [Abstract Oral Deoxynivalenol Toxicity in Harlan Sprague Dawley (Hsd:Sprague Dawley® SD®) Rat Dams and Their Offspring] [Synopsis Oral Deoxynivalenol Toxicity in Harlan Sprague Dawley (Hsd:Sprague Dawley® SD®) Rat Dams and Their Offspring] Huang MC, Furr JR, Robinson VG, Betz L, Shockley K, Cunny H, Witt K, Waidyanatha S, Germolec D. February 2021

PM2.5 Concentration and Composition in Subway Systems in the Northeastern United States [Abstract PM2.5 Concentration and Composition in Subway Systems in the Northeastern United States] [Synopsis PM2.5 Concentration and Composition in Subway Systems in the Northeastern United States] Luglio DG, Katsigeorgis M, Hess J, Kim R, Adragna J, Raja A, Gordon C, Fine J, Thurston G, Gordon T, Vilcassim MJR. February 2021

A Methodological Pipeline to Generate an Epigenetic Marker of Prenatal Exposure to Air Pollution Indicators [Abstract A Methodological Pipeline to Generate an Epigenetic Marker of Prenatal Exposure to Air Pollution Indicators] [Synopsis A Methodological Pipeline to Generate an Epigenetic Marker of Prenatal Exposure to Air Pollution Indicators] Wang Y, Perera F, Guo J, Riley KW, Durham T, Ross Z, Ananth CV, Baccarelli A, Wang S, Herbstman JB. January 2021

Controlling Nanochannel Orientation and Dimensions in Graphene-based Nanofluidic Membranes [Abstract Controlling Nanochannel Orientation and Dimensions in Graphene-based Nanofluidic Membranes] [Synopsis Controlling Nanochannel Orientation and Dimensions in Graphene-based Nanofluidic Membranes] Liu M, Weston PJ, Hurt RH. January 2021

Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15 Reveal Insight Into Nuclease Specificity and Dynamics [Abstract Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15 Reveal Insight Into Nuclease Specificity and Dynamics] [Synopsis Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15 Reveal Insight Into Nuclease Specificity and Dynamics] Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. January 2021

Electronic-cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial [Abstract Electronic-cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial] [Synopsis Electronic-cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial] Rebuli ME, Glista-Baker E, Hoffman JR, Duffney PF, Robinette C, Speen AM, Pawlak EA, Dhingra R, Noah TL, Jaspers I. January 2021

Enhanced Adsorption of Per- and Polyfluoroalkyl Substances (PFAS) By Edible, Nutrient-Amended Montmorillonite Clays [Abstract Enhanced Adsorption of Per- and Polyfluoroalkyl Substances (PFAS) By Edible, Nutrient-Amended Montmorillonite Clays] [Synopsis Enhanced Adsorption of Per- and Polyfluoroalkyl Substances (PFAS) By Edible, Nutrient-Amended Montmorillonite Clays] Wang M, Orr AA, Jakubowski JM, Bird KE, Casey CM, Hearon SE, Tamamis P, Phillips TD. January 2021

Risk Assessment Analysis for Maternal Autoantibody-Related Autism (MAR-ASD): A Subtype of Autism [Abstract Risk Assessment Analysis for Maternal Autoantibody-Related Autism (MAR-ASD): A Subtype of Autism] [Synopsis Risk Assessment Analysis for Maternal Autoantibody-Related Autism (MAR-ASD): A Subtype of Autism] Ramirez-Celis A, Becker M, Nuno M, Schauer J, Aghaeepour N, Van de Water J. January 2021

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning [Abstract The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning] [Synopsis The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning] Marvel SW, House JS, Wheeler M, Song K, Zhou YH, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM. January 2021

Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures [Abstract Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures] [Synopsis Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures] Chang Y, Huynh CTT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. December 2020

Epoxide Hydrolase 3 (Ephx3) Gene Disruption Reduces Ceramide Linoleate Epoxide Hydrolysis and Impairs Skin Barrier Function [Abstract Epoxide Hydrolase 3 (Ephx3) Gene Disruption Reduces Ceramide Linoleate Epoxide Hydrolysis and Impairs Skin Barrier Function] [Synopsis Epoxide Hydrolase 3 (Ephx3) Gene Disruption Reduces Ceramide Linoleate Epoxide Hydrolysis and Impairs Skin Barrier Function] Edin ML, Yamanashi H, Boeglin WE, Graves JP, DeGraff LM, Lih FB, Zeldin DC, Brash AR. December 2020

Heterozygous Germline BLM Mutations Increase Susceptibility to Asbestos and Mesothelioma [Abstract Heterozygous Germline BLM Mutations Increase Susceptibility to Asbestos and Mesothelioma] [Synopsis Heterozygous Germline BLM Mutations Increase Susceptibility to Asbestos and Mesothelioma] Bononi A, Goto K, Ak G, Yoshikawa Y, Emi M, Pastorino S, Carparelli L, Ferro A, Nasu M, Kim JH, Suarez JS, Xu R, Tanji M, Takinishi Y, Minaai M, Novelli F, Pagano I, Gaudino G, Pass HI, Groden J, Grzymski JJ, Metintas M, Akarsu M, Morrow B, Hassan R, Yang H, Carbone M. December 2020

High-Throughput Screening to Identify Chemical Cardiotoxic Potential [Abstract High-Throughput Screening to Identify Chemical Cardiotoxic Potential] [Synopsis High-Throughput Screening to Identify Chemical Cardiotoxic Potential] Krishna S, Berridge B, Kleinstreuer N. December 2020

Multiple, Objectively Measured Sleep Dimensions Including Hypoxic Burden and Chronic Kidney Disease: Findings From the Multi-Ethnic Study of Atherosclerosis [Abstract Multiple, Objectively Measured Sleep Dimensions Including Hypoxic Burden and Chronic Kidney Disease: Findings From the Multi-Ethnic Study of Atherosclerosis] [Synopsis Multiple, Objectively Measured Sleep Dimensions Including Hypoxic Burden and Chronic Kidney Disease: Findings From the Multi-Ethnic Study of Atherosclerosis] Jackson CL, Umesi C, Gaston SA, Azarbarzin A, Lunyera J, McGrath JA, Jackson Ii WB, Diamantidis CJ, Boulware E, Lutsey PL, Redline S. December 2020

Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-specific Olfactory Impairment in Mice [Abstract Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-specific Olfactory Impairment in Mice] [Synopsis Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-specific Olfactory Impairment in Mice] [Story Paraquat Inhalation, a Translationally Relevant Route of Exposure: Disposition to the Brain and Male-specific Olfactory Impairment in Mice] Anderson T, Merrill AK, Eckard ML, Marvin E, Conrad K, Welle K, Oberdorster G, Sobolewski M, Cory-Slechta DA. December 2020

Ancestry-dependent Gene Expression Correlates with Reprogramming to Pluripotency and Multiple Dynamic Biological Processes [Abstract Ancestry-dependent Gene Expression Correlates with Reprogramming to Pluripotency and Multiple Dynamic Biological Processes] [Synopsis Ancestry-dependent Gene Expression Correlates with Reprogramming to Pluripotency and Multiple Dynamic Biological Processes] Bisogno LS, Yang J, Bennett BD, Ward JM, Mackey LC, Annab LA, Bushel PR, Singhal S, Schurman SH, Byun JS, Napoles AM, Perez-Stable EJ, Fargo DC, Gardner K, Archer TK. November 2020

Association of Ambient PM2.5 Exposure With Maternal Bone Strength in Pregnant Women From Mexico City: A Longitudinal Cohort Study [Abstract Association of Ambient PM2.5 Exposure With Maternal Bone Strength in Pregnant Women From Mexico City: A Longitudinal Cohort Study] [Synopsis Association of Ambient PM2.5 Exposure With Maternal Bone Strength in Pregnant Women From Mexico City: A Longitudinal Cohort Study] Wu H, Kioumourtzoglou MA, Just AC, Kloog I, Sanders A, Svensson K, McRae N, Tamayo-Ortiz M, Solano-González M, Wright RO, Tellez-Rojo MM, Baccarelli AA. November 2020

Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife [Abstract Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife] [Synopsis Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife] Reuben A, Elliott ML, Abraham WC, Broadbent J, Houts RM, Ireland D, Knodt AR, Poulton R, Ramrakha S, Hariri AR, Caspi A, Moffitt TE. November 2020

Depot Medroxyprogesterone Acetate Use and Blood Lead Levels in a Cohort of Young Women [Abstract Depot Medroxyprogesterone Acetate Use and Blood Lead Levels in a Cohort of Young Women] [Synopsis Depot Medroxyprogesterone Acetate Use and Blood Lead Levels in a Cohort of Young Women] Upson K, Harmon QE, Heffron R, Hall JE, Wise LA, Wegienka G, Tokar EJ, Baird DD. November 2020

Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model [Abstract Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model] [Synopsis Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model] Panlilio JM, Aluru N, Hahn ME. November 2020

Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota [Abstract Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota] [Synopsis Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota] Sitarik AR, Arora M, Austin C, Bielak LF, Eggers S, Johnson CC, Lynch SV, Kyun Park S, Hank Wu KH, Yong GJM, Cassidy-Bushrow AE. November 2020

Next-generation GRAB Sensors for Monitoring Dopaminergic Activity in Vivo [Abstract Next-generation GRAB Sensors for Monitoring Dopaminergic Activity in Vivo] [Synopsis Next-generation GRAB Sensors for Monitoring Dopaminergic Activity in Vivo] Sun F, Zhou J, Dai B, Qian T, Zeng J, Li X, Zhuo Y, Zhang Y, Wang Y, Qian C, Tan K, Feng J, Dong H, Lin D, Cui G, Li Y. November 2020

Tolerability and Age-dependent Toxicokinetics Following Perinatal Hydroxyurea Treatment in Sprague Dawley Rats [Abstract Tolerability and Age-dependent Toxicokinetics Following Perinatal Hydroxyurea Treatment in Sprague Dawley Rats] [Synopsis Tolerability and Age-dependent Toxicokinetics Following Perinatal Hydroxyurea Treatment in Sprague Dawley Rats] Huang MC, Turner KJ, Vallant M, Robinson VG, Lu Y, Price CJ, Fennell TR, Silinski MA, Waidyanatha S, Ryan KR, Black SR, Fernando RA, McIntyre BS. November 2020

Vitamin D Treatment During Pregnancy and Maternal and Neonatal Cord Blood Metal Concentrations at Delivery: Results of a Randomized Controlled Trial in Bangladesh [Abstract Vitamin D Treatment During Pregnancy and Maternal and Neonatal Cord Blood Metal Concentrations at Delivery: Results of a Randomized Controlled Trial in Bangladesh] [Synopsis Vitamin D Treatment During Pregnancy and Maternal and Neonatal Cord Blood Metal Concentrations at Delivery: Results of a Randomized Controlled Trial in Bangladesh] Jukic AMZ, Zuchniak A, Qamar H, Ahmed T, Mahmud AA, Roth DE. November 2020

Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches [Abstract Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches] [Synopsis Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches] Collins BJ, Kerns SP, Aillon K, Mueller G, Rider CV, DeRose EF, London RE, Harnly JM, Waidyanatha S. October 2020

Constitutive Expression of Progesterone Receptor Isoforms Promotes the Development of Hormone-dependent Ovarian Neoplasms [Abstract Constitutive Expression of Progesterone Receptor Isoforms Promotes the Development of Hormone-dependent Ovarian Neoplasms] [Synopsis Constitutive Expression of Progesterone Receptor Isoforms Promotes the Development of Hormone-dependent Ovarian Neoplasms] [Story Constitutive Expression of Progesterone Receptor Isoforms Promotes the Development of Hormone-dependent Ovarian Neoplasms] Wetendorf M, Li R, Wu SP, Liu J, Creighton CJ, Wang T, Janardhan KS, Willson CJ, Lanz RB, Murphy BD, Lydon JP, DeMayo FJ. October 2020

Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs) [Abstract Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)] [Synopsis Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)] Hsieh JH, Sedykh A, Mutlu E, Germolec DR, Auerbach SS, Rider CV. October 2020

High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives [Abstract High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives] [Synopsis High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives] Mazzone CM, Liang-Guallpa J, Li C, Wolcott NS, Boone MH, Southern M, Kobzar NP, Salgado IA, Reddy DM, Sun F, Zhang Y, Li Y, Cui G, Krashes MJ. October 2020

Legacy and Novel Per- and Polyfluoroalkyl Substances in Juvenile Seabirds From the U.S. Atlantic Coast [Abstract Legacy and Novel Per- and Polyfluoroalkyl Substances in Juvenile Seabirds From the U.S. Atlantic Coast] [Synopsis Legacy and Novel Per- and Polyfluoroalkyl Substances in Juvenile Seabirds From the U.S. Atlantic Coast] Robuck AR, Cantwell MG, McCord JP, Addison LM, Pfohl M, Strynar MJ, McKinney R, Katz DR, Wiley DN, Lohmann R. October 2020

Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011 [Abstract Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011] [Synopsis Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011] Nigra AE, Navas-Acien A. September 2020

Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients [Abstract Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients] [Synopsis Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients] Manne S, Kondru N, Jin H, Serrano GE, Anantharam V, Kanthasamy A, Adler CH, Beach TG, Kanthasamy AG. September 2020

Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells [Abstract Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells] [Synopsis Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells] Serpa GL, Renton ND, Lee N, Crane MJ, Jamieson AM. September 2020

Identifying Issues and Priorities in Reporting Back Environmental Health Data [Abstract Identifying Issues and Priorities in Reporting Back Environmental Health Data] [Synopsis Identifying Issues and Priorities in Reporting Back Environmental Health Data] Lebow-Skelley E, Yelton S, Janssen B, Erdei E, Pearson MA. September 2020

Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort [Abstract Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort] [Synopsis Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort] Mitro SD, Sagiv SK, Fleisch AF, Jaacks LM, Williams PL, Rifas-Shiman SL, Calafat AM, Hivert MF, Oken E, James-Todd TM. September 2020

Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant [Abstract Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant] [Synopsis Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant] Lozoya OA, Xu F, Grenet D, Wang T, Grimm SA, Godfrey V, Waidyanatha S, Woychik RP, Santos JH. September 2020

Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break [Abstract Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break] [Synopsis Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break] Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. September 2020

Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging [Abstract Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging] [Synopsis Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging] Lujan SA, Longley MJ, Humble MH, Lavender CA, Burkholder A, Blakely EL, Alston CL, Gorman GS, Turnbull DM, McFarland R, Taylor RW, Kunkel TA, Copeland WC. September 2020

Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans [Abstract Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans] [Synopsis Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans] Baird DD, Patchel SA, Saldana TM, Umbach DM, Cooper T, Wegienka G, Harmon QE. September 2020

Vitamin E is Necessary for Zebrafish Nervous System Development [Abstract Vitamin E is Necessary for Zebrafish Nervous System Development] [Synopsis Vitamin E is Necessary for Zebrafish Nervous System Development] Head B, La Du J, Tanguay RL, Kioussi C, Traber MG. September 2020

Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging [Abstract Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging] [Synopsis Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging] Chen C, Xun P, Kaufman JD, Hayden KM, Espeland MA, Whitsel EA, Serre ML, Vizuete W, Orchard T, Harris WS, Wang X, Chui HC, Chen JC, He K. August 2020

Genetic and Functional Insights Into the Fractal Structure of the Heart [Abstract Genetic and Functional Insights Into the Fractal Structure of the Heart] [Synopsis Genetic and Functional Insights Into the Fractal Structure of the Heart] Meyer HV, Dawes TJW, Serrani M, Bai W, Tokarczuk P, Cai J, de Marvao A, Henry A, Lumbers RT, Gierten J, Thumberger T, Wittbrodt J, Ware JS, Rueckert D, Matthews PM, Prasad SK, Costantino ML, Cook SA, Birney E, O'Regan DP. August 2020

HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer [Abstract HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] [Synopsis HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] [Story HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] Xu Q, Li Y, Gao X, Kang K, Williams JG, Tong L, Liu J, Ji M, Deterding LJ, Tong X, Locasale JW, Li L, Shats I, Li X. August 2020

InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics [Abstract InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics] [Synopsis InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics] Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen HJ, Kiledjian M, Shears SB. August 2020

Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study [Abstract Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study] [Synopsis Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study] Welch BM, Keil AP, van 't Erve TJ, Deterding LJ, Williams JG, Lih FB, Cantonwine DE, McElrath TF, Ferguson KK. August 2020

Metabolic Effects of Air Pollution Exposure and Reversibility [Abstract Metabolic Effects of Air Pollution Exposure and Reversibility] [Synopsis Metabolic Effects of Air Pollution Exposure and Reversibility] Rajagopalan S, Park B, Palanivel R, Vinayachandran V, Deiuliis JA, Gangwar RS, Das LM, Yin J, Choi Y, Al-Kindi S, Jain MK, Hansen KD, Biswal S. August 2020

Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children [Abstract Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children] [Synopsis Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children] Stratakis N, Conti DV, Jin R, Margetaki K, Valvi D, Siskos AP, Maitre L, Garcia E, Varo N, Zhao Y, Roumeliotaki T, Vafeiadi M, Urquiza J, Fernandez-Barres S, Heude B, Basagana X, Casas M, Fossati S, Grazuleviciene R, Andrusaityte S, Uppal K, McEachan RR, Papadopoulou E, Robinson O, Haug LS, Wright J, Vos MB, Keun HC, Vrijheid M, Berhane KT, McConnell R, Chatzi L. August 2020

A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework [Abstract A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework] [Synopsis A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework] Eagles-Smith CA, Willacker JJ, Nelson SJ, Flanagan Pritz CM, Krabbenhoft DP, Chen CY, Ackerman JT, Grant EHC, Pilliod DS. July 2020

Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure [Abstract Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure] [Synopsis Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure] Quiros-Alcala L, Hansel NN, McCormack M, Calafat AM, Ye X, Peng RD, Matsui EC. July 2020

Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy [Abstract Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy] [Synopsis Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy] Barnhill LM, Khuansuwan S, Juarez D, Murata H, Araujo JA, Bronstein JM. July 2020

Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma [Abstract Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma] [Synopsis Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma] Quiros-Alcala L, Hansel NN, McCormack M, Calafat AM, Ye X, Peng RD, Matsui EC. July 2020

InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference [Abstract InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference] [Synopsis InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference] Borrel A, Mansouri K, Nolte S, Saddler T, Conway M, Schmitt C, Kleinstreuer NC. July 2020

QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2 [Abstract QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2] [Synopsis QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2] Alves VM, Bobrowski T, Melo-Filho CC, Korn D, Auerbach S, Schmitt C, Muratov EN, Tropsha A. July 2020

The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort [Abstract The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort] [Synopsis The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort] Blomberg AJ, Nyhan MM, Bind MA, Vokonas P, Coull BA, Schwartz J, Koutrakis P. July 2020

Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body [Abstract Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body] [Synopsis Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body] Borrel A, Auerbach SS, Houck KA, Kleinstreuer NC. July 2020

Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation [Abstract Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation] [Synopsis Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation] Ding N, Harlow SD, Randolph JF, Calafat AM, Mukherjee B, Batterman S, Gold EB, Park SK. June 2020

A Universal Gut-microbiome-derived Signature Predicts Cirrhosis [Abstract A Universal Gut-microbiome-derived Signature Predicts Cirrhosis] [Synopsis A Universal Gut-microbiome-derived Signature Predicts Cirrhosis] Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, Brenner DA, Sirlin CB, Knight R, Downes M, Evans RM, Loomba R. June 2020

Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation [Abstract Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation] [Synopsis Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation] Madenspacher JH, Morrell ED, Gowdy KM, McDonald JG, Thompson BM, Muse G, Martinez J, Thomas S, Mikacenic C, Nick JA, Abraham E, Garantziotis S, Stapleton RD, Meacham JM, Thomassen MJ, Janssen WJ, Cook DN, Wurfel MM, Fessler MB. June 2020

Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation [Abstract Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] [Synopsis Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] [Story Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] Gambini A, Stein P, Savy V, Grow EJ, Papas BN, Zhang Y, Kenan AC, Padilla-Banks E, Cairns BR, Williams CJ. June 2020

Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II [Abstract Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II] [Synopsis Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II] Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS, Bell DA. June 2020

Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes [Abstract Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes] [Synopsis Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes] Gwinn WM, Auerbach SS, Parham F, Stout MD, Waidyanatha S, Mutlu E, Collins B, Paules RS, Merrick BA, Ferguson S, Ramaiahgari S, Bucher JR, Sparrow B, Toy H, Gorospe J, Machesky N, Shah RR, Balik-Meisner MR, Mav D, Phadke DP, Roberts G, DeVito MJ. June 2020

Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice [Abstract Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice] [Synopsis Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice] Gu Z, Smith KG, Alexander GM, Guerreiro I, Dudek SM, Gutkin B, Jensen P, Yakel JL. June 2020

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis [Abstract HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis] [Synopsis HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis] Bai G, Kermi C, Stoy H, Schiltz CJ, Bacal J, Zaino AM, Hadden MK, Eichman BF, Lopes M, Cimprich KA. June 2020

House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population [Abstract House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] [Synopsis House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] [Story House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] Lee MK, Wyss AB, Carnes MU, Richards M, Parks CG, Beane Freeman LE, Thorne PS, Umbach DM, Azcarate-Peril MA, Peddada SD, London SJ. June 2020

Increasing Prevalence of Antinuclear Antibodies in the United States [Abstract Increasing Prevalence of Antinuclear Antibodies in the United States] [Synopsis Increasing Prevalence of Antinuclear Antibodies in the United States] [Story Increasing Prevalence of Antinuclear Antibodies in the United States] Dinse GE, Parks CG, Weinberg CR, Co CA, Wilkerson J, Zeldin DC, Chan EKL, Miller FW. June 2020

Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage [Abstract Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage] [Synopsis Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage] Hayne CK, Schmidt CA, Haque MI, Matera AG, Stanley RE. June 2020

Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2 [Abstract Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2] [Synopsis Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2] Schellenberg MJ, Appel CD, Riccio AA, Butler LR, Krahn JM, Liebermann JA, Cortes-Ledesma F, Williams RS. June 2020

Analgesic Use at Ovulation and Implantation and Human Fertility [Abstract Analgesic Use at Ovulation and Implantation and Human Fertility] [Synopsis Analgesic Use at Ovulation and Implantation and Human Fertility] Jukic AMZ, Padiyara P, Bracken MB, McConnaughey DR, Steiner AZ. May 2020

Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3 [Abstract Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3] [Synopsis Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3] Takaku M, Grimm SA, De Kumar B, Bennett BD, Wade PA. May 2020

Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations [Abstract Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations] [Synopsis Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations] Yan X, Sedykh A, Wang W, Yan B, Zhu H. May 2020

Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations [Abstract Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations] [Synopsis Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations] Greeson KW, Fowler KL, Estave PM, Kate Thompson S, Wagner C, Clayton Edenfield R, Symosko KM, Steves AN, Marder EM, Terrell ML, Barton H, Koval M, Marcus M, Easley CA 4th. May 2020

Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats [Abstract Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats] [Synopsis Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats] Patten KT, Gonzalez EA, Valenzuela A, Berg E, Wallis C, Garbow JR, Silverman JL, Bein KJ, Wexler AS, Lein PJ. May 2020

Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood [Abstract Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood] [Synopsis Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood] Trevino LS, Dong J, Kaushal A, Katz TA, Jangid RK, Robertson MJ, Grimm SL, Ambati CSR, Putluri V, Cox AR, Kim KH, May TD, Gallo MR, Moore DD, Hartig SM, Foulds CE, Putluri N, Coarfa C, Walker CL. May 2020

Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase [Abstract Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase] [Synopsis Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase] Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. May 2020

Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease [Abstract Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease] [Synopsis Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease] Guo M, Wang J, Zhao Y, Feng Y, Han S, Dong Q, Cui M, Tieu K. May 2020

Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat [Abstract Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat] [Synopsis Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat] Watson ATD, Sutherland VL, Cunny H, Miller-Pinsler L, Furr J, Hebert C, Collins B, Waidyanatha S, Smith L, Vinke T, Aillon K, Xie G, Shockley KR, McIntyre BS. May 2020

A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014 [Abstract A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014] [Synopsis A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014] Nguyen VK, Kahana A, Heidt J, Polemi K, Kvasnicka J, Jolliet O, Colacino JA. April 2020

Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring [Abstract Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] [Synopsis Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] [Story Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] Sun BZ, Moster D, Harmon QE, Wilcox AJ. April 2020

Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration [Abstract Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration] [Synopsis Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration] Fragola G, Mabb AM, Taylor-Blake B, Niehaus JK, Chronister WD, Mao H, Simon JM, Yuan H, Li Z, McConnell MJ, Zylka MJ. April 2020

Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas [Abstract Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas] [Synopsis Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas] Casey JA, Su JG, Henneman LRF, Zigler C, Neophytou AM, Catalano R, Gondalia R, Chen Y-T, Kaye L, Moyer SS, Combs V, Simrall G, Smith T, Sublett J, Barrett MA. April 2020

Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice [Abstract Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] [Synopsis Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] Yamashita H, Surapureddi S, Kovi RC, Bhusari S, Ton TV, Li J-L, Shockley K, Peddada SD, Gerrish KE, Rider CV, Hoenerhoff MJ, Sills RC, Pandiri AR. April 2020

A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing [Abstract A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing] [Synopsis A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing] Waidyanatha S, Pierfelice J, Cristy T, Mutlu E, Burback B, Rider CV, Ryan K. March 2020

Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis [Abstract Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis] [Synopsis Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis] Mao J, Jain A, Denslow ND, Nouri MZ, Chen S, Wang T, Zhu N, Koh J, Sarma SJ, Sumner BW, Lei Z, Sumner LW, Bivens NJ, Roberts RM, Tuteja G, Rosenfeld CS. March 2020

Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function [Abstract Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function] [Synopsis Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function] TC, McCord J, Guillette M, Polera ME, Rachels KT, Morgeson C, Kotlarz N, Knappe DRU, Reading BJ, Strynar N, Belcher SM. March 2020

Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4 [Abstract Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4] [Synopsis Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4] Diaz-Jimenez D, Petrillo MG, Busada JT, Hermoso MA, Cidlowski JA. March 2020

Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats [Abstract Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats] [Synopsis Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats] Behl M, Willson CJ, Cunny H, Foster PMD, McIntyre B, Shackelford C, Shockley KR, McBride S, Turner K, Waidyanatha S, Blystone CR. March 2020

Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search [Abstract Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search] [Synopsis Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search] Beckwitt EC, Jang S, Carnaval Deweiler I, Kuper J, Sauer F, Simon N, Bretzler J, Watkins SC, Carell T, Kisker C, Van Houten B. March 2020

Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein [Abstract Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] [Synopsis Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] [Story Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] Jefferson WN, Padilla-Banks E, Suen AA, Royer LJ, Zeldin SM, Arora R, Williams C. March 2020

Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet [Abstract Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] [Synopsis Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] [Story Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] Qin Y, Grimm SA, Roberts JD, Chrysovergis K, Wade PA. February 2020

Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study [Abstract Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study] [Synopsis Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study] Cheng I, Tseng C, Wu J, Yang J, Conroy SM, Shariff-Marco S, Li L, Hertz A, Gomez SL, Le Marchand L, Whittemore AS, Stram DO, Ritz B, Wu AH. February 2020

Bisphenol A Activates an Innate Viral Immune Response Pathway [Abstract Bisphenol A Activates an Innate Viral Immune Response Pathway] [Synopsis Bisphenol A Activates an Innate Viral Immune Response Pathway] Sowers ML, Tang H, Tian B, Goldblum R, Midoro-Horiuti T, Zhang K. February 2020

Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling [Abstract Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling] [Synopsis Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling] Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB. February 2020

Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium [Abstract Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium] [Synopsis Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium] Wu SP, Anderson ML, Wang T, Zhou L, Emery OM, Li X, DeMayo FJ. February 2020

Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity [Abstract Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity] [Synopsis Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity] Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SAW, Nardone A, DeAngelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan CC, Mancini MA. February 2020

Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX) [Abstract Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)] [Synopsis Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)] Blake BE, Cope HA, Hall SM, Keys RD, Mahler RD, McCord J, Scott B, Stapleton HM, Strynar MJ, Elmore SA, Fenton SE. February 2020

NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly [Abstract NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly] [Synopsis NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly] He F, Antonucci L, Yamachika S, Zhang Z, Taniguchi K, Umemura A, Hatzivassiliou G, Roose-Girma M, Reina-Campos M, Duran A, Diaz-Meco MT, Moscat J, Sun B, Karin M. February 2020

Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice [Abstract Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice] [Synopsis Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice] Zhang L, Rimal B, Nichols RG, Tian Y, Smith PB, Hatzakis E, Chang SC, Butenhoff JL, Peters JM, Patterson AD. February 2020

Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice [Abstract Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice] [Synopsis Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice] Majhi PD, Sharma A, Roberts AL, Daniele E, Majewski AR, Chuong LM, Black AL, Vandenberg LN, Schneider SS, Dunphy KA, Jerry DJ. January 2020

Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace [Abstract Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace] [Synopsis Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace] Lin WC, Gowdy KM, Madenspacher JH, Zemans RL, Yamamoto K, Lyons-Cohen M, Nakano H, Janardhan K, Williams CJ, Cook DN, Mizgerd JP, Fessler MB. January 2020

N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription [Abstract N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription] [Synopsis N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription] Liu J, Dou X, Chen C, Chen C, Liu C, Xu MM, Zhao S, Shen B, Gao Y, Han D, He C. January 2020

Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease [Abstract Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease] [Synopsis Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease] Younan D, Petkus AJ, Widaman KF, Wang X, Casanova R, Espeland MA, Gatz M, Henderson VW, Manson JE, Rapp SR, Sachs BC, Serre ML, Gaussoin SA, Barnard R, Saldana S, Vizuete W, Beavers DP, Salinas JA, Chui HC, Renick SM, Shumaker SA, Chen JC. January 2020

Privacy Risks of Sharing Data from Environmental Health Studies [Abstract Privacy Risks of Sharing Data from Environmental Health Studies] [Synopsis Privacy Risks of Sharing Data from Environmental Health Studies] Boronow KE, Perovich LJ, Sweeney L, Yoo JS, Rudel RA, Brown P, Brody JG. January 2020

Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity [Abstract Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity] [Synopsis Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity] Kinyamu HK, Bennett BD, Bushel PR, Archer TK. January 2020