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Your Environment. Your Health.

The MYORISK Study (Environmental Risk Factors for the Anti-Synthetase Syndrome)

Study Background

This study intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness. Adults and children diagnosed with myositis within the last year may enroll by completing questionnaires and donating blood and urine samples.

Like other complex diseases, autoimmune diseases are the result of numerous causes, including genetic and environmental factors. Some researchers believe that people who are susceptible to autoimmune disorders develop them when the body reacts to environmental or other factors by creating white blood cells that attack the body's own tissues, which then progresses to autoimmune diseases. These immune-triggered disorders can overlap with one another to some extent, but most autoimmune diseases have certain distinct triggers.

Principal Investigator

Frederick W. Miller
Frederick W. Miller, M.D., Ph.D.
Deputy Chief, Clinical Research Branch and Principal Investigator
Tel 984-287-3593
Fax 301-451-5585
millerf@mail.nih.gov
P.O. Box 12233
Mail Drop F1-09
Durham, N.C. 27709

Adult Subjects

Adam I. Schiffenbauer
Adam I. Schiffenbauer, M.D.
Staff Clinician
Environmental Autoimmunity Group, Clinical Research Branch
Tel 301-451-6270
adam.schiffenbauer@nih.gov
10 Center Dr
Clinical Center Surgical Wing
Bethesda, MD 20892-1627

Pediatric Subjects

Lisa Rider, M.D.
Lisa Rider, M.D.
Deputy Chief and Staff Clinician, Environmental Autoimmunity Group
Tel 301-451-6272
Fax 301-480-2813
riderl@mail.nih.gov
10 Center Dr
Hatfield Clinical Research Center
Bethesda, MD 20892-1301
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