Effect of Innate Immunity on the Inflammatory Response to Endotoxin
Open for Recruitment
Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body’s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancer.
The study will involve one 60-minute visit at the NIEHS Clinical Research Unit (CRU) in Research Triangle Park, North Carolina, and volunteers will be compensated for their time. If eligible, participation includes a review of your medical and family history, collection of vital signs, and a blood draw.
For more information on this study, please visit the Clinical Trials Study page.
Enrolling by invitation only.
You may be eligible for this study if you meet the following criteria:
- Current participant in the Environmental Polymorphism Registry (EPR)
- At least 18 years of age
- Male or non-pregnant
- Willing to fast (with the exception of water) from midnight prior to the study visit
- Ability to travel to the CRU
- Healthy volunteers as defined by the International Red Cross guidelines (Healthy means that an individual feels well and can perform normal activities. If the individual has a chronic condition such as diabetes or high blood pressure, healthy also means that they are being treated and the condition is under control).
What will you do?
- Participate in one 60-minute visit at the National Institute of Environmental Health Sciences (NIEHS) Clinical Research Unit (CRU) in Research Triangle Park, NC.
- Visit includes a review of medical history, collection of vital signs, and providing a blood sample.
- Compensation for time and effort at the completion of the study visit is $45.
- If you are eligible, you may be invited to participate in this study more than once. You will receive the same compensation for your time and effort for each visit completed.
- Be part of a research study to help scientists at NIEHS understand the role of certain genes in human disease such as cancer and heart disease.
- Receive compensation for your time and effort.
Sample collections are conducted at the NIEHS Clinical Research Unit located in Research Triangle Park, North Carolina
Protocol Number: 10-E-0129
Enrollment and Contact Information
For more information and to enroll in this study, please contact Grace Isshiki at (919) 541-4973.
Michael B. Fessler, M.D.
Deputy Chief, Immunity, Inflammation, and Disease Laboratory and Principal Investigator
P.O. Box 12233Mail Drop D2-01Durham, N.C. 27709