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NIEHS Studies - Open for Recruitment

NIEHS Studies - Open for Recruitment

Title Topic / Condition Location Participants Contact
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study This is a study on the controlled exposure of BPA and its effects on the body. Research Triangle Park, NC

Healthy males or females between the ages of 25 to 45 years

Nicole Edwards at (919) 316-4976

Black Cohosh Study Black Cohosh is an herbal supplement that is taken by some women to treat hot flashes, cramps, or other related symptoms. Researchers are studying the health effects of black cohosh in women who have been taking the supplement for at least 3 months. Researchers are investigating whether black cohosh may affect folate and B12 levels, anemia, and metabolomics profiles. They are also investigating whether black cohosh induces genetic changes.

Research Triangle Park, NC

Females, 18 years and older

Nicole Edwards
(919) 316-4976

Blood Vessel Study Researchers want to study healthy adults who have genes that may affect their endothelial function. More information on these genes may provide more information on genetic risk for certain diseases. Research Triangle Park, NC

Enrolling by Invitation Only

Nicole Edwards at (919) 316-4976

Body Weight & Puberty Study Researchers want to find out if body weight affects when a girl starts puberty

Research Triangle Park, NC

Healthy girls aged 8-14

Nicole Edwards at 919-316-4976

CaREFREE Study: Calorie Restriction, Environment, and Fitness: Reproductive Effects Evaluation This study intends to understand how nutrition, fitness, and the environment affect women's reproductive cycles.

Research Triangle Park, NC

Healthy women aged 18-28 Janet Hall, M.D.
1-855-MYNIEHS
Cox-2 Gene and the Immune System The COX-2 gene may help decide the balance of cell types that the body makes as part of the immune system. Research Triangle Park, NC

Enrolling by Invitation Only

Nicole Edwards at (919) 316-4976

E-Cigs and Smoking Study Researchers are trying to develop new biomarkers of tobacco smoke exposure and e-cigarette use.

Research Triangle Park, NC

Males and Females, aged 18-55

Nicole Edwards
(919) 316-4976

Effect of Innate Immunity on the Inflammatory Response to Endotoxin This study will look at how differences in people’s genes may cause differences in their blood cells’ response to exposed environmental factors Research Triangle Park, NC

Enrolling by Invitation Only

Nicole Edwards at (919) 316-4976

Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage The study will look at how changes in the tumor suppressor gene p53 lead to changes in inflammation and the ability to repair DNA damage.

Research Triangle Park, NC

Enrolling by Invitation Only

Nicole Edwards at (919) 316-4976

Environmental Polymorphisms Registry – DNA Registry for Diseases The registry will help examine risk factors for common conditions such as asthma, diabetes, cardiovascular disease, and cancer.

Research Triangle Park, NC

Male or female age 18 years or older

Nicole Edwards
(919) 316-4976

Environmental Risk Factors for the Anti-Synthetase Syndrome – The MYORISK Study The study will investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness. Bethesda, MD

Adults and children diagnosed with myositis within the last two years and healthy volunteers

Deona Cooper at (919) 451-7667

Environmental Risk Factors for the Development of Myositis in Military Personnel Researchers will compare military personnel with and without myositis to look for common factors that may have led to the disease. Bethesda, MD

Military personnel and military contractors diagnosed with myositis while active duty and healthy military volunteers

Komal Patel at (301) 443-6053

Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease NIEHS Investigators will look at how differences in people’s genes may cause their body to respond in different ways to glucocorticoids. Glucocorticoids are hormones made by the human body that are essential for life but in excess may cause diseases such as obesity and diabetes.

Research Triangle Park, NC

Enrolling by Invitation Only

Nicole Edwards at (919) 316-4976

Inhaled Nanosilver Study The goal of the Inhaled Nanosilver Study is to assess the impact of inhaled silver nanoparticles on immune responses in the lung. Research Triangle Park, NC

Healthy, non-smoking, males or females between the ages of 18-60 years

Nicole Edwards at (919) 316-4976

Innate Immunity Signal Transduction in Human Leukocytes To investigate the response of immune cells from the bloodstream.

Research Triangle Park, NC

Healthy, males or females between the ages of 18-65 years

Nicole Edwards at (919) 316-4976

NHALES Study: Natural History of Asthma with Longitudinal Environmental Sampling The study will help scientists understand how bacteria and other factors in the environment affect people who have moderate to severe asthma. Research Triangle Park, NC

Non-smoking males and females with moderate to severe asthma, aged 18-60

Nicole Edwards at (919) 316-4976

NIEHS-EPA Pilot Study of Exposure to Chemicals in Consumer Products This study intends to test and improve the ways that studies gather data about how chemicals in products come in contact with consumers.

Research Triangle Park, NC

Healthy women aged 35-74 Kristina Thayer, Ph.D.
1-855-MYNIEHS
Pathogenic Studies in Families with Twins or Siblings Discordant for Systemic Rheumatic Disorders The research team will study the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, in which one has the disease and the other does not. Bethesda, MD

Adults with a rheumatic disease, children with a rheumatic disease and a twin or non-twin sibling within 5 years of age without a rheumatic disease, and healthy volunteers

Cayden Maican at (301) 451-2348

Psoriasis Study Researchers are studying the differences in immune response between a person with psoriasis, a person with chronic inflammatory disease and a healthy person.

Research Triangle Park, NC

Males and Females, aged 18-70

Nicole Edwards
(919) 316-4976

Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing Researchers are developing a registry of biologic and environmental samples with which to develop and test specific laboratory assays.

Research Triangle Park, NC

Male or non-pregnant female age 18 or older

Nicole Edwards at (919) 316-4976

Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies This study will evaluate subjects with adult- and childhood-onset myositis to learn more about the cause of the disease and associated immune system changes. Bethesda, MD

Adults and children with a rheumatic disease and healthy volunteers

Cayden Maican at (301) 451-2348

TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection NIEHS scientists will explore whether there is a difference in lung cells from healthy and asthmatic participants and how these cells respond to exposure to respiratory syncytial virus (RSV), a very common virus that leads to cold-like symptoms. The study will also evaluate if a protein in lung cells called TGF-Beta increases risk of infection with RSV.

Research Triangle Park, NC

Non-asthmatic & mild asthmatic participants 18-60 years of age

Nicole Edwards at (919) 316-4976

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