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Your Environment. Your Health.

NIEHS Studies - Open for Recruitment

NIEHS Studies - Open for Recruitment

Title Topic / Condition Location Join A Study
Adult and Juvenile Myositis (Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies) This study will evaluate subjects with adult- and childhood-onset myositis to learn more about the cause of the disease and associated immune system changes.Bethesda, MD Study Overview: Adult and Juvenile Myositis
Agricultural Health Study The Agricultural Health Study (AHS) is a prospective study of cancer and other health outcomes to help farmers and their families live healthier livesIowa City, IA and Research Triangle Park, NC
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study This is a study on the controlled exposure of BPA and its effects on the body.Research Triangle Park, NC
Black Cohosh Study Black Cohosh is an herbal supplement that is taken by some women to treat hot flashes, cramps, or other related symptoms. Researchers are studying the health effects of black cohosh in women who have been taking the supplement for at least 3 months. Researchers are investigating whether black cohosh may affect folate and B12 levels, anemia, and metabolomics profiles. They are also investigating whether black cohosh induces genetic changes.

Research Triangle Park, NC

Blood Vessel Study Researchers want to study healthy adults who have genes that may affect their endothelial function. More information on these genes may provide more information on genetic risk for certain diseases.Research Triangle Park, NC
Body Weight & Puberty Study (Investigating the Impact of Obesity on Pubertal Development in Girls) Researchers want to find out if body weight affects when a girl starts puberty

Research Triangle Park, NC

Study Overview: Body Weight and Puberty Study
BPA Monitoring Study in Cashiers The study was designed to measure BPA levels before and after occupation exposure to cash register thermal paper.Research Triangle Park, NC
Cockroach Allergen Intervention The purpose of this study was to determine how intensive an effective extermination must be.Research Triangle Park, NC
Cox-2 Gene and the Immune System The COX-2 gene may help decide the balance of cell types that the body makes as part of the immune system.Research Triangle Park, NC Study Overview: Cox-2 Gene and the Immune System
Detroit Study of Environment, Lifestyle & Fibroids (SELF) SELF was the first and only research study of uterine fibroids to use ultrasound screening for women who have not been diagnosed with fibroids.Detroit, MI
DNA & Your Environment (Environmental Polymorphisms Registry – DNA Registry for Diseases) The registry will help examine risk factors for common conditions such as asthma, diabetes, cardiovascular disease, and cancer.

Research Triangle Park, NC

Study Overview: DNA & Your Environment
Dust Mite Reduction Study The study delved into whether in-home test kits decreased dust mite allergen levels in homes with children who are sensitive to dust mites.Bethesda, MD
E-Cigs and Smoking Study Researchers are trying to develop new biomarkers of tobacco smoke exposure and e-cigarette use.

Research Triangle Park, NC

Study Overview: E-Cigs and Smoking Study
Exposure to Indoor Allergens in Day Care Facilities The study evaluated allergen levels and their predictors in day care facilities.
Healthy Homes The purpose of the study is to learn how to make homes more supportive of healthy eating and physical activity.Emory University, Centers for Disease Control and Prevention, Southwest Georgia Cancer Coalition
Immunity Cells in Blood (Innate Immunity Signal Transduction in Human Leukocytes) To investigate the response of immune cells from the bloodstream.

Research Triangle Park, NC

Study Overview: Immunity Cells in Blood
Inflammatory Response to DNA Damage (Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage) The study will look at how changes in the tumor suppressor gene p53 lead to changes in inflammation and the ability to repair DNA damage.

Research Triangle Park, NC

Study Overview: Inflammatory Response to DNA Damage
Inflammatory Response to Endotoxin (Effect of Innate Immunity on the Inflammatory Response to Endotoxin) This study will look at how differences in people’s genes may cause differences in their blood cells’ response to exposed environmental factorsResearch Triangle Park, NC Study Overview: Inflammatory Response to Endotoxin
Inhaled Nanosilver Study The goal of the Inhaled Nanosilver Study is to assess the impact of inhaled silver nanoparticles on immune responses in the lung.Research Triangle Park, NC
Inner-City Asthma Study (ICAS) ICAS Study evaluates the effectiveness of two types of interventions to reduce the prevalence and severity of asthma in children.Research Triangle Park, NC
Metabolic Disease (Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease) NIEHS Investigators will look at how differences in people’s genes may cause their body to respond in different ways to glucocorticoids. Glucocorticoids are hormones made by the human body that are essential for life but in excess may cause diseases such as obesity and diabetes.

Research Triangle Park, NC

Study Overview: Metabolic Disease
Myositis in Military Personnel (Environmental Risk Factors for the Development of Myositis in Military Personnel) Researchers will compare military personnel with and without myositis to look for common factors that may have led to the disease.Bethesda, MD
National Health & Nutrition Examination Survey (NHANES) NHANES allowed researchers to examine the role of diet, obesity, diabetes, and genetics in the development of allergic disease.
National Survey of Lead & Allergens in Housing (NSLAH) NSLAH measures levels of lead in dust, soil, and paint, and the levels of various indoor allergens in floor and bedding dust.Research Triangle Park, NC
NHALES Study (Natural History of Asthma with Longitudinal Environmental Sampling) The study will help scientists understand how bacteria and other factors in the environment affect people who have moderate to severe asthma.Research Triangle Park, NC Study Overview: NHALES Asthma Study
NIEHS-EPA Pilot Study of Exposure to Chemicals in Consumer Products This study intends to test and improve the ways that studies gather data about how chemicals in products come in contact with consumers.

Research Triangle Park, NC

Nutrition and Menstrual Cycles Study (CaREFREE Study: Calorie Restriction, Environment, and Fitness: Reproductive Effects Evaluation) This study intends to understand how nutrition, fitness, and the environment affect women's reproductive cycles.

Research Triangle Park, NC

Study Overview: Nutrition and Menstrual Cycles
Plasma Study This project will look at how oxidative stress occurs in smokers compared to non-smokers.

Research Triangle Park, NC

Polycystic Ovary Syndrome in Twin Sisters The goal of this study is to find out whether polycystic ovary syndrome in twins is caused by genetics, environmental triggers or a combination of both.Research Triangle Park, NC
Psoriasis Study Researchers are studying the differences in immune response between a person with psoriasis, a person with chronic inflammatory disease and a healthy person.

Research Triangle Park, NC

Rheumatic Disorders in Siblings (Pathogenic Studies in Families with Twins or Siblings Discordant for Systemic Rheumatic Disorders) The research team will study the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, in which one has the disease and the other does not.Bethesda, MD Study Overview: Rheumatic Disorders in Siblings
RSV Infection and Asthma (TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection) NIEHS scientists will explore whether there is a difference in lung cells from healthy and asthmatic participants and how these cells respond to exposure to respiratory syncytial virus (RSV), a very common virus that leads to cold-like symptoms. The study will also evaluate if a protein in lung cells called TGF-Beta increases risk of infection with RSV.

Research Triangle Park, NC

Study Overview: RSV Infection and Asthma
Sample Collection Registry (Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing) Researchers are developing a registry of biologic and environmental samples with which to develop and test specific laboratory assays.

Research Triangle Park, NC

Study Overview: Sample Collection Registry
Sister Study or el Studio de Hermanas The purpose of the Sister Study is to learn how the environment and genes may interact to affect the chances of getting breast cancer. The Sister Study completed enrollment in March 2009.Research Triangle Park, NC
The GuLF STUDY (or Gulf Long Term Follow-Up Study) The GuLF STUDY (or Gulf Long Term Follow-Up Study) is a health study for individuals who responded to the Deepwater Horizon oil spill in the Gulf of Mexico in 2010.Research Triangle Park, NC
The MYORISK Study (Environmental Risk Factors for the Anti-Synthetase Syndrome) The study will investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness.Bethesda, MD Study Overview: Myorisk Study
The Ovarian Health Study Anti-müllerian hormone (AMH) is a hormone produced in the ovaries. Researchers are investigating the possibility of developing lab assays to measure AMH in urine.

Research Triangle Park, NC


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