Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

DNA & Your Environment (Environmental Polymorphisms Registry – DNA Registry for Diseases)

Study Background

The Environmental Polymorphisms Registry (EPR) is a long-term initiative to collect approximately 20,000 DNA samples from individuals. These DNA samples will be used to examine risk factors for common health conditions such as heart disease, cancer, diabetes, asthma, and Alzheimer’s disease. Genetic data, along with health information (e.g., family history of disease, environmental exposure, socioeconomic status, and lifestyle data) will be used to select participants for voluntary follow-up studies to help researchers prevent, diagnose, and treat common health conditions in individual patients and whole populations.

By donating a blood sample to the EPR, you will be helping scientists discover changes in our genes that make us more or less sensitive to environmental factors and that can increase or decrease our risk for disease.

Principal Investigator

Shepherd H. Schurman
Shepherd H. Schurman, M.D.
Associate Medical Director, NIEHS Clinical Research Unit
Principal Investigator, EPR
Tel 984-287-4411
Fax 301-480-3416
P.O. Box 12233
Mail Drop CU-01
Durham, N.C. 27709

Collaborating Investigators

Adam I. Schiffenbauer
Adam I. Schiffenbauer, M.D.
Staff Clinician
Environmental Autoimmunity Group, Clinical Research Branch
Tel 301-451-6270
10 Center Dr
Clinical Center Surgical Wing
Bethesda, MD 20892-1627
Not Pictured
Rita Volochayev, Ph.D., C.R.N.P., C.P.M.N.
Family Nurse Practitioner
Tel 301-451-6266
10 Center Dr
Magnuson Clinical Center
Bethesda, MD 20892-1627

Project Manager

Not Pictured
Emily Learner, Ph.D.
Project Director, EPR
Tel 919-287-4353

EPR Steering Committee

The EPR Steeing Committee is composed of

  • Stavros Garantziotis: Medical Director, Clinical Research Unit and EPR Steering Committee Chair, NIEHS
  • Shepherd H. Schurman: Associate Medical Director, Clinical Research Unit and EPR Principal Investigator, NIEHS
  • Perry J. Blackshear: Group Leader, Polypeptide Hormone Action Group, NIEHS
  • Fred Miller: Chief, Environmental Autoimmunity Group, Office of Clinical Research, NIEHS
  • Jack Taylor, Group Leader, Molecular & Genetic Epidemiology Group, NIEHS
  • Paul Watkins, Director, UNC Institute for Drug Safety Sciences
  • Subject matter experts – as needed for specific requests
  • Michael B. Fessler, Acting Chief, Immunity, Inflammation, and Disease Laboratory and Principal Investigator
to Top