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Your Environment. Your Health.

E-Cigs and Smoking Study

Open for Recruitment

Study Background

E-Cigs and Smoking Studies

Open for Recruitment

Additional Information

Cigarettes vs e-cigaretts
Study Flyer(768KB)

According to the Centers for Disease Control and Prevention, cigarette smoking causes more than 480,000 deaths each year in the United States, which translates to causing nearly one of every five deaths. Although the health impacts of smoking, such as cardiovascular and respiratory disease, cancer, and reduced fertility are well-documented, the goal of the E-Cigs and Smoking Study is to develop new biomarkers of tobacco smoke exposure or e-cigarette use. The biomarkers will be based on analysis of DNA methylation, which is the addition of methyl groups to DNA and is one of several epigenetic processes that occur in cells.

This content is available to use on your website.
Please visit NIEHS Syndication to get started.


You may be eligible for this study if you are a:

  • Healthy man or woman aged 18-55
  • Current cigarette smoker or user of nicotine-containing e-cigarettes (can be using both)

The definition of healthy for this study means that you feel well and can perform normal activities. If you have a chronic condition, such as high blood pressure, healthy can also mean that you are being treated and the condition is under control.

What will you do?

  • Visit the NIEHS Clinical Research Unit in Research Triangle Park, NC for a one-hour study visit.
  • Donate blood, urine, and saliva samples.

Why Participate?

  • Be part of a research project to help scientists at NIEHS understand the differences between cigarette users, e-cigarette users, and non-smokers.
  • Participants will receive monetary compensation of $60 for providing samples for this research project.

Study Location

Sample collections are conducted at the NIEHS Clinical Research Unit located in Research Triangle Park, North Carolina.

Protocol Number: 10-E-0063

Enrollment and Contact Information

Nicole Edwards
Study Coordinator
Clinical Research Unit (CRU)
Tel (919) 316-4976
Nicole P. Edwards

Principal Investigator

Douglas A. Bell, Ph.D.
Douglas A. Bell, Ph.D.
Principal Investigator
Tel 984-287-3862
P.O. Box 12233
Mail Drop C3-03
Durham, N.C. 27709
Rebecca L. Church, Clinical Research Coordinator
Tel 984-287-4421
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