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Your Environment. Your Health.

Nutrition and Menstrual Cycles (CaREFREE Study: Calorie Restriction, Environment, and Fitness: Reproductive Effects Evaluation)

Open for Recruitment

Study Background

Many women develop irregular menstrual cycles which may make it difficult to become pregnant and increase the risk of osteoporosis. Why do exercise and diet have this effect in some women but not others? This study will help us understand how nutrition, exercise, and the environment affect women's reproductive cycles.

Participants will be asked to track three consecutive menstrual cycles and come in for 9-10 visits on specific days. Participants will undergo two 5-day exercise and diet regimens provided by the study. Procedures include a physical exam, fitness testing, measurement of body fat and bone density, blood sampling, and daily at home blood & urine tests.

Participants will be compensated for their time.

For more information on this study, please visit the Clinical Trials Study webpage.

group of four women laughing

Contact Information

To learn more about this study, contact us here.

Principal Investigator

Janet E. Hall, M.D., M.S.
Janet E. Hall, M.D., M.S.
Clinical Director and Principal Investigator
Tel 984-287-3647
janet.hall@nih.gov
P.O. Box 12233
Mail Drop A2-03
Durham, N.C. 27709
Abbie Smith-Ryan
Abbie Smith-Ryan, Ph.D.
Associate Researcher
Department of Exercise & Sport Science
University of North Carolina at Chapel Hill
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