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Your Environment. Your Health.

Inner-City Asthma Study (ICAS)

Closed for Recruitment

Study / Trial Background

The Inner-City Asthma Study (ICAS) is a 7-site cooperative study sponsored by the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Allergy and Infectious Diseases (NIAID). ICAS was designed to evaluate the effectiveness of two types of interventions to reduce asthma morbidity and severity among 937 inner-city children, ages 5-11, with moderate to severe asthma. Each participant was enrolled for two years, the intervention year and a follow-up year. An Environmental Intervention and a Physician Feedback Intervention were studied. 

The Physician Feedback intervention entailed a new communication and education system that provided physicians with up-to-date information on the child's symptoms, medication use, and health care use.

The Inner-City Asthma Study (ICAS) is a 7-site cooperative study sponsored by the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Allergy and Infectious Diseases (NIAID). ICAS was designed to evaluate the effectiveness of two types of interventions to reduce asthma morbidity and severity among 937 inner-city children, ages 5-11, with moderate to severe asthma. Each participant was enrolled for two years, the intervention year and a follow-up year. An Environmental Intervention and a Physician Feedback Intervention were studied.

The Physician Feedback intervention entailed a new communication and education system that provided physicians with up-to-date information on the child's symptoms, medication use, and health care use.

The Environmental Intervention focused on the home environments of the children, involving education and reduction of environmental exposures including cockroaches, dust mites, environmental tobacco smoke (ETS), mold, furry pets, and rodents.

More information about how this customized intervention reduced symptoms in inner-city children can be found in the publications related to this study.

Eligibility

The study has completed enrollment.

Study / Trial Location

Sample collections are conducted at the NIEHS Clinical Research Unit located in Research Triangle Park, North Carolina

Principal Investigator

John R. Bucher, Ph.D.
John R. Bucher, Ph.D.
Associate Director, National Toxicology Program
Director, National Toxicology Program Division
Tel 919-541-4532
Fax 919-541-4255
bucher@niehs.nih.gov
P.O. Box 12233
Mail Drop K2-02
Durham, N.C. 27709