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Your Environment. Your Health.

Kelly A. Shipkowski, Ph.D.

Systems Toxicology Group

Kelly A. Shipkowski
Kelly A. Shipkowski, Ph.D.
Fellow — IRTA
Tel 984-287-3186
530 Davis Dr
Keystone Building
Durham, NC 27713

Kelly Shipkowski, Ph.D. is an Intramural Research Training Award (IRTA) Fellow in the Toxicology Branch of the Division of the National Toxicology Program (DNTP) at the National Institute of Environmental Health Sciences. Currently working as a trainee study scientist, Shipkowski works with individuals both within and outside of the Toxicology Branch to examine the safety of chemical compounds that have been nominated to the NTP testing program. Her responsibilities include designing and implementing toxicology studies of different chemical classes, including pharmaceutical, herbal, and environmental agents. Shipkowski is also responsible for authoring and reviewing NTP Technical Reports and manuscripts for publication. Her primary research interests include respiratory toxicology and immunotoxicology.

Shipkowski double-majored and received a B.S. in both Biology and Chemistry from Methodist University in 2010 and completed her Ph.D. in Toxicology at North Carolina State University under the mentorship of Dr. James Bonner in 2015. Her doctoral research focused on respiratory toxicology, specifically working to understand the inflammatory consequences of exposure to multi-walled carbon nanotubes during pre-existing allergic airway inflammation.

Selected Publications

  • Shipkowski, KA, Taylor, AJ, Thompson, EA, Glista-Baker, EE, Sayers, BC, Messenger, ZJ, Bauer, RN, Jaspers, I, Bonner, JC. An allergic lung microenvironment suppresses carbon nanotube-induced inflammasome activation via STAT6-dependent inhibition of caspase-1. PLOS One. 2015. 10(6): e0128888. (doi:10.1371/journal.pone.0128888). [Abstract]
  • Thompson, EA, Sayers, BC, Glista-Baker, EE, Shipkowski, KA, Ihrie, MD, Duke, KS, Taylor, AJ, Bonner, JC. STAT-1 attenuates murine allergen-induced airway remodeling and exacerbation by carbon nanotubes. AJRCMB. 2015. (doi:10.1165/rcmb.2014-0221OC). [Abstract]
  • Taylor, AJ, McClure, CD, Shipkowski, KA, Thompson, EA, Hussain, S, Garantziotis, S, Parsons, GN, and Bonner, JC. Atomic layer deposition coating of carbon nanotubes with aluminum oxide alters pro-fibrogenic cytokine expression by human mononuclear phagocytes in vitro and reduces lung fibrosis in mice in vivo. PLOS One. 2014. (doi: 10.1371/journal.pone.0106870). [Abstract]
  • Thompson, EA, Sayers, BC, Glista-Baker, EE, Shipkowski, KA, Taylor, AJ, Bonner, JC. Innate immune responses to nanoparticle exposure in the lung. J Env Immun and Tox. 2014. 1(3): 150-156. [Abstract]