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Your Environment. Your Health.

Program Operations Branch

The NIH intramural research program has shifted all non-mission-critical laboratory operations to a maintenance phase in order to promote physical distancing and diminished transmission risk of COVID-19. Effective Monday, March 23, 2020, only mission-critical functions within NIH research laboratories will be supported.

Michelle J. Hooth, Ph.D.
Michelle J. Hooth, Ph.D.
Toxicologist and Chief, Program Operations Branch
Tel 984-287-3140
Fax 919-541-4255
P.O. Box 12233
Mail Drop K2-07
Durham, N.C. 27709

Research Summary

The Program Operations Branch (POB) provides critical scientific and information technology expertise necessary to conduct and support the National Toxicology Program (NTP) research efforts. Staff members are responsible for the following general functions:

  • Acquiring and validating new methods and capabilities to address specific requirements for NTP studies.
  • Advising NTP staff and directing the work of NTP contract study laboratories conducting general toxicology, carcinogenicity, and developmental and reproductive toxicology studies.
  • Providing expertise, direction, and oversight for a number of NTP support functions including studies of absorption, distribution, metabolism and excretion (ADME) and toxicokinetics, analytical chemistry and quality assessment.
  • Conducting activities related to maintaining and developing databases for NTP studies as well as data capture and retrieval systems.
  • Receiving, tracking, maintaining, and disseminating NTP documents and data for both the NTP public and internal websites.
Program Operations Branch Logo NTP: Chemistry, ADME, Toxicology, Study Management, Information

To facilitate these activities, the Program Operations Branch is organized into the following:

  • Chemistry and ADME (Absorption, Distribution, Metabolism and Excretion) Resources Group (CARG)
  • Toxicology Study Management Workgroup (SMW)
  • Information and Data Management Workgroup (IDMW).

These groups work with a variety of NTP staff to accomplish program goals. Please see specific activities and interests of each section on the Organization webpage.

Robbin Guy
Robbin Y. Guy
Program Specialist

Tel 984-287-3136
Fax 301-480-3009
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