Stem Cell Toxicology Group
- Erik Tokar, Ph.D.
Group Leader, Stem Cell Toxicology Group
- Tel 919-541-3951
- P.O. Box 12233Mail Drop E1-07Durham, N.C. 27709
The Stem Cells Toxicology Group investigates the roles of stem cells in disease manifestation induced by exposure to environmental toxicants. The Group provides expertise in areas of stem cell biology and toxicology, and works on National Toxicology Program (NTP) Laboratory mission-related projects that involve stem cells or other areas as required. While stem cells/cancer stem cells and potential mechanisms of action in inorganic carcinogenesis will be the major focus, research efforts will also extend beyond cancer to include those diseases and conditions associated with exposure to NTP chemicals.
Major areas of research:
- Developing models of chemical carcinogenesis and other human diseases
- Defining roles and elucidating mechanisms of action of stem cells and cancer stem cells during chemical carcinogenesis
- Investigating developmental effects and outcomes of environmental toxicant exposures