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Your Environment. Your Health.

NTP Laboratory

The NIH intramural research program has shifted all non-mission-critical laboratory operations to a maintenance phase in order to promote physical distancing and diminished transmission risk of COVID-19. Effective Monday, March 23, 2020, only mission-critical functions within NIH research laboratories will be supported.

B. Alex Merrick, Ph.D.
B A. Merrick, Ph.D.
Acting Chief, National Toxicology Program Laboratory
Group Leader, Predictive Toxicology and Screening Group
Group Leader, Molecular Toxicology and Genomics Group
Tel 984-287-3161
P.O. Box 12233
Mail Drop E1-05
Durham, N.C. 27709

Research Summary

The mission of the National Toxicology Program (NTP) Laboratory is to provide research support and conduct investigative toxicology for the NTP. Laboratory work is project-driven in collaboration with members of Health Effects Initiatives (HEIs) and Program Management Teams (PMTs) within the NTP to advance the program mission. Investigative work uses NTP Lab’s research capabilities to identify human health hazards from environmental and chemical exposures and further mechanistic understanding of environmental toxicity contributing to human disease.

The NTP Laboratory has several goals:

  • To provide on-site, program-responsive, laboratory support to HEI and PMT project teams in NTP for screening, prioritization and mechanistic understanding of chemical effects and environmental factors related to human exposure and health.
  • To produce and deliver high quality, laboratory data in a timely manner.
  • To develop novel in vitro systems, alternative animal models, new cellular and molecular assays in a research setting that may lead to standardized and scalable tests for NTP’s testing program.
  • To conduct bioanalytical disposition and metabolite analysis of environmental and test chemicals in experimental systems.
  • To collaborate with researchers and environmental stakeholders for program-responsive outcomes to NTP.
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