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Selected Publications

Polypeptide Hormone Action Group

  1. Qiu LQ, Stumpo DJ, Blackshear PJ. Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype. Journal of immunology Baltimore, Md. 2012 188(10):5150-9. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=22491258) ]
  2. Ghosh S, Hoenerhoff MJ, Clayton N, Myers P, Stumpo DJ, Maronpot RR, Blackshear PJ. Left-Sided Cardiac Valvulitis in Tristetraprolin-Deficient Mice. The Role of Tumor Necrosis Factor {alpha}. Am J Pathol. 2010 Jan 21. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=20093488) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832167/?tool=pubmed) ]
  3. Weimer JM, Yokota Y, Stanco A, Stumpo DJ, Blackshear PJ, Anton ES. MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex. Development. 2009 Sep;136(17):2965-2675. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19666823) ] [Full Text (http://dev.biologists.org/content/136/17/2965.long) ]
  4. Stumpo DJ, Broxmeyer HE, Ward T, Cooper S, Hangoc G, Chung YJ, Shelley WC, Richfield EK, Ray MK, Yoder MC, Aplan PD, Blackshear PJ. Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood. 2009 Sep 17;114(12):2401-2410. Epub 2009 Jul 24. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19633199) ] [Full Text (http://bloodjournal.hematologylibrary.org/cgi/content/full/114/12/2401) ]
  5. Schaljo B, Kratochvill F, Gratz N, Sadzak I, Sauer I, Hammer M, Vogl C, Strobl B, Müller M, Blackshear PJ, Poli V, Lang R, Murray PJ, Kovarik P. Tristetraprolin is required for full anti-inflammatory response of murine macrophages to IL-10. J Immunol. 2009 Jul 15;183(2):1197-1206. Epub 2009 Jun 19. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19542371) ] [Full Text (http://www.jimmunol.org/cgi/content/full/183/2/1197) ]
  6. Brennan SE, Kuwano Y, Alkharouf N, Blackshear PJ, Gorospe M, Wilson GM. The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res. 2009 Jun 15;69(12):5168-5176. Epub 2009 Jun 2. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19491267) ] [Full Text (http://cancerres.aacrjournals.org/cgi/content/full/69/12/5168) ]
  7. Ogilvie RL, Sternjohn JR, Rattenbacher B, Vlasova IA, Williams DA, Hau HH, Blackshear PJ, Bohjanen PR. Tristetraprolin mediates interferon-gamma mRNA decay. J Biol Chem. 2009 Apr 24;284(17):11216-11223. Epub 2009 Mar 3. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19258311) ] [Full Text (http://www.jbc.org/content/284/17/11216.long) ]
  8. Cuthbertson BJ, Blackshear PJ. Chapter 4. Evaluating the control of mRNA decay in fission yeast. Methods Enzymol. 2008;449:73-95. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19215754) ] [Full Text (http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7CV2-4VK64G8-9&_user=4333534&_coverDate=12%2F31%2F2008&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000000150&_version=1&_urlVersion=0&_userid=4333534&md5=9a47de999c84e6128336e51f9797a30d) ]
  9. Horner TJ, Lai WS, Stumpo DJ, Blackshear PJ. Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin. Mol Cell Biol. 2009 Apr;29(8):1999-2010. Epub 2009 Feb 2. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19188452) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663294/?tool=pubmed) ]
  10. Gay EA, Klein RC, Melton MA, Blackshear PJ, Yakel JL. Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide. J Pharmacol Exp Ther. 2008 Dec;327(3):884-890. Epub 2008 Sep 23. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18812491) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709273/?tool=pmcentrez) ]
  11. Frederick ED, Ramos SB, Blackshear PJ. A unique C-terminal repeat domain maintains the cytosolic localization of the placenta-specific tristetraprolin family member ZFP36L3. J Biol Chem. 2008 May 23;283(21):14792-14800. Epub 2008 Mar 26. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18367448) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671328/?tool=pubmed) ]
  12. Stoecklin G, Tenenbaum SA, Mayo T, Chittur SV, George AD, Baroni TE, Blackshear PJ, Anderson P. Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem. 2008 Apr 25;283(17):11689-11699. Epub 2008 Feb 6. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18256032) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431067/?tool=pubmed) ]
  13. Zhang D, Harry GJ, Blackshear PJ, Zeldin DC. G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. J Biol Chem. 2008 Mar 28;283(13):8580-8590. Epub 2008 Jan 24. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18218630) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365754/?tool=pubmed) ]
  14. Cao H, Deterding LJ, Blackshear PJ. Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin. Expert Rev Proteomics. 2007 Dec;4(6):711-726. Review. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18067411) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674331/?tool=pubmed) ]
  15. Cuthbertson BJ, Liao Y, Birnbaumer L, Blackshear PJ. Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe. J Biol Chem. 2008 Feb 1;283(5):2586-2594. Epub 2007 Nov 27. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18042546) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736560/?tool=pubmed) ]
  16. Carrick DM, Blackshear PJ. Comparative expression of tristetraprolin (TTP) family member transcripts in normal human tissues and cancer cell lines. Arch Biochem Biophys. 2007 Jun 15;462(2):278-285. Epub 2007 Apr 26. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17517366) ] [Full Text (http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WB5-4NKB0FP-2&_user=4333534&_coverDate=06%2F15%2F2007&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000000150&_version=1&_urlVersion=0&_userid=4333534&md5=71f7881d379747cabb29ec8799d70137) ]
  17. Zhang D, Zeldin DC, Blackshear PJ. Regulatory factor X4 variant 3: a transcription factor involved in brain development and disease. J Neurosci Res. 2007 Dec;85(16):3515-3522. Review. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17510980) ]
  18. Sharma S, Stumpo DJ, Balajee AS, Bock CB, Lansdorp PM, Brosh RM Jr, Blackshear PJ. RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol. 2007 Mar;27(5):1784-1794. Epub 2006 Dec 11. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17158923?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820448/?tool=pubmed) ]
  19. Brewer BY, Ballin JD, Fialcowitz-White EJ, Blackshear PJ, Wilson GM. Substrate dependence of conformational changes in the RNA-binding domain of tristetraprolin assessed by fluorescence spectroscopy of tryptophan mutants. Biochemistry. 2006 Nov 21;45(46):13807-13817. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17105199) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1640280/?tool=pubmed) ]
  20. Lai WS, Parker JS, Grissom SF, Stumpo DJ, Blackshear PJ. Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts. Mol Cell Biol. 2006 Dec;26(24):9196-9208. Epub 2006 Oct 9. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17030620?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698545/?tool=pubmed) ]
  21. Alexopoulou L, Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G. Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity. Eur J Immunol. 2006 Oct;36(10):2768-2780. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16983719?dopt=Abstract) ]
  22. Zhang D, Stumpo DJ, Graves JP, DeGraff LM, Grissom SF, Collins JB, Li L, Zeldin DC, Blackshear PJ. Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development. J Neurochem. 2006 Aug;98(3):860-875. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16893423?dopt=Abstract) ]
  23. Carrick DM, Chulada P, Donn R, Fabris M, McNicholl J, Whitworth W, Blackshear PJ. Genetic variations in ZFP36 and their possible relationship to autoimmune diseases. J Autoimmun. 2006 May;26(3):182-196. Epub 2006 Mar 20. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16546352?dopt=Abstract) ] [Full Text (http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WHC-4JHMHXP-1&_user=4333534&_coverDate=05%2F31%2F2006&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000000150&_version=1&_urlVersion=0&_userid=4333534&md5=dab61bda998c7fc5e2cc521cd2bc7600) ]
  24. Sauer I, Schaljo B, Vogl C, Gattermeier I, Kolbe T, Müller M, Blackshear PJ, Kovarik P. Interferons limit inflammatory responses by induction of tristetraprolin. Blood. 2006 Jun 15;107(12):4790-4797. Epub 2006 Mar 2. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16514065?dopt=Abstract) ] [Full Text (http://bloodjournal.hematologylibrary.org/cgi/content/full/107/12/4790) ]
  25. Cao H, Deterding LJ, Venable JD, Kennington EA, Yates JR 3rd, Tomer KB, Blackshear PJ. Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem J. 2006 Feb 15;394(Pt 1):285-297. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16262601?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386027/?tool=pubmed) ]
  26. Katsanou V, Papadaki O, Milatos S, Blackshear PJ, Anderson P, Kollias G, Kontoyiannis DL. HuR as a negative posttranscriptional modulator in inflammation. Mol Cell. 2005 Sep 16;19(6):777-789. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16168373?dopt=Abstract) ]
  27. Lai WS, Carrick DM, Blackshear PJ. Influence of nonameric AU-rich tristetraprolin-binding sites on mRNA deadenylation and turnover. J Biol Chem. 2005 Oct 7;280(40):34365-34377. Epub 2005 Aug 1. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16061475?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/280/40/34365.long) ]
  28. Blackshear PJ, Phillips RS, Ghosh S, Ramos SB, Richfield EK, Lai WS. Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins. Biol Reprod. 2005 Aug;73(2):297-307. Epub 2005 Apr 6. Erratum in: Biol Reprod. 2005 Nov;73(5):1072. Ramos, Silvia V B [corrected to Ramos, Silvia B V]. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15814898?dopt=Abstract) ] [Full Text (http://www.biolreprod.org/content/73/2/297.long) ]
  29. Ogilvie RL, Abelson M, Hau HH, Vlasova I, Blackshear PJ, Bohjanen PR. Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J Immunol. 2005 Jan 15;174(2):953-961. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15634918?dopt=Abstract) ] [Full Text (http://www.jimmunol.org/cgi/content/full/174/2/953) ]
  30. Carrick DM, Lai WS, Blackshear PJ. The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis. Arthritis Res Ther. 2004;6(6):248-264. Epub 2004 Oct 8. Review. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15535838) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064869/?tool=pubmed) ]
  31. Ramos SB, Stumpo DJ, Kennington EA, Phillips RS, Bock CB, Ribeiro-Neto F, Blackshear PJ. The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development. Development. 2004 Oct;131(19):4883-4893. Epub 2004 Sep 1. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15342461) ] [Full Text (http://dev.biologists.org/content/131/19/4883.long) ]
  32. Stumpo DJ, Byrd NA, Phillips RS, Ghosh S, Maronpot RR, Castranio T, Meyers EN, Mishina Y, Blackshear PJ. Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Mol Cell Biol. 2004 Jul;24(14):6445-6455. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15226444) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC434251/?tool=pubmed) ]
  33. Brewer BY, Malicka J, Blackshear PJ, Wilson GM. RNA sequence elements required for high affinity binding by the zinc finger domain of tristetraprolin: conformational changes coupled to the bipartite nature of Au-rich MRNA-destabilizing motifs. J Biol Chem. 2004 Jul 2;279(27):27870-27877. Epub 2004 Apr 26. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15117938?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/279/27/27870.long) ]
  34. Cao H, Tuttle JS, Blackshear PJ. Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein. J Biol Chem. 2004 May 14;279(20):21489-21499. Epub 2004 Mar 9. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15010466?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351392/?tool=pubmed) ]
  35. Phillips K, Kedersha N, Shen L, Blackshear PJ, Anderson P. Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2011-2016. Epub 2004 Feb 9. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/14769925?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC357043/?tool=pubmed) ]
  36. Blackshear PJ, Phillips RS, Vazquez-Matias J, Mohrenweiser H. Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins. Prog Nucleic Acid Res Mol Biol. 2003;75:43-68. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/14604009?dopt=Abstract) ]
  37. Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC. Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development. 2003 Oct;130(19):4539-4552. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12925582?dopt=Abstract) ] [Full Text (http://dev.biologists.org/content/130/19/4539.long) ]
  38. Scarlett CO, Blackshear PJ. Neuroanatomical development in the absence of PKC phosphorylation of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein. Brain Res Dev Brain Res. 2003 Aug 12;144(1):25-42. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12888215?dopt=Abstract) ] [Full Text (http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6SYW-48VTJJ8-2&_user=4333534&_coverDate=08%2F12%2F2003&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000000150&_version=1&_urlVersion=0&_userid=4333534&md5=cec62a69cd037138bcbe863190f43e2c) ]
  39. Lai WS, Kennington EA, Blackshear PJ. Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease. Mol Cell Biol. 2003 Jun;23(11):3798-3812. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12748283?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155217/?tool=pubmed) ]
  40. Cao H, Dzineku F, Blackshear PJ. Expression and purification of recombinant tristetraprolin that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinases. Arch Biochem Biophys. 2003 Apr 1;412(1):106-120. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12646273?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351391/?tool=pubmed) ]
  41. Blackshear PJ, Lai WS, Kennington EA, Brewer G, Wilson GM, Guan X, Zhou P. Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates. J Biol Chem. 2003 May 30;278(22):19947-19955. Epub 2003 Mar 14. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12639954?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/278/22/19947.long) ]
  42. Blackshear PJ. Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover. Biochem Soc Trans. 2002 Nov;30(Pt 6):945-952. Review. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/12440952?dopt=Abstract) ] [Full Text (http://www.biochemsoctrans.org/bst/030/0945/bst0300945.htm) ]
  43. Phillips RS, Ramos SB, Blackshear PJ. Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling. J Biol Chem. 2002 Mar 29;277(13):11606-11613. Epub 2002 Jan 16. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11796723?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/277/13/11606.long) ]
  44. Lai WS, Kennington EA, Blackshear PJ. Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs. J Biol Chem. 2002 Mar 15;277(11):9606-9613. Epub 2002 Jan 8. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11782475?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/277/11/9606.long) ]
  45. Carballo E, Blackshear PJ. Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome. Blood. 2001 Oct 15;98(8):2389-2395. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11588035?dopt=Abstract) ] [Full Text (http://bloodjournal.hematologylibrary.org/cgi/content/full/98/8/2389) ]
  46. Carballo E, Cao H, Lai WS, Kennington EA, Campbell D, Blackshear PJ. Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway. J Biol Chem. 2001 Nov 9;276(45):42580-42587. Epub 2001 Sep 6. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11546803?dopt=Abstract) ] [Full Text (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351389/?tool=pubmed) ]
  47. Spizz G, Blackshear PJ. Overexpression of the myristoylated alanine-rich C-kinase substrate inhibits cell adhesion to extracellular matrix components. J Biol Chem. 2001 Aug 24;276(34):32264-32273. Epub 2001 Jun 18. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11413143?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/276/34/32264.long) ]
  48. Lai WS, Blackshear PJ. Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a poly(A) tail. J Biol Chem. 2001 Jun 22;276(25):23144-23154. Epub 2001 Mar 28. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/11279239?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/276/25/23144.long) ]
  49. Lai WS, Carballo E, Thorn JM, Kennington EA, Blackshear PJ. Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA. J Biol Chem. 2000 Jun 9;275(23):17827-17837. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/10751406?dopt=Abstract) ] [Full Text (http://www.jbc.org/content/275/23/17827.long) ]
  50. Carballo E, Lai WS, Blackshear PJ. Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood. 2000 Mar 15;95(6):1891-1899. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/10706852?dopt=Abstract) ] [Full Text (http://bloodjournal.hematologylibrary.org/cgi/content/full/95/6/1891) ]

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