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Your Environment. Your Health.

Selected Publications

Matrix Biology Group


  1. Brass, D.M., Hollingsworth, J.W., McElvania-Tekippe, E., Garantziotis, S., Hossain, I., and Schwartz, D.A. 2007. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol 293:L77-83. [Abstract ( ]
  2. Garantziotis, S., Hollingsworth, J.W., Ghanayem, R.B., Timberlake, S., Zhuo, L., Kimata, K., and Schwartz, D.A. 2007. Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury. J Immunol 179:4187-4192. [Abstract ( ]
  3. Garantziotis, S., and Palmer, S.M. 2007. Genetics and genomics in human lung transplantation. Expert Rev Respir Med 1:271-278. [Abstract ( ]
  4. Garantziotis, S., Palmer, S.M., Snyder, L.D., Ganous, T., Chen, B.J., Wang, T., Cook, D.N., and Schwartz, D.A. 2007. Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. Transplantation 84:1012-1019. [Abstract ( ]
  5. Hollingsworth, J.W., Li, Z., Brass, D.M., Garantziotis, S., Timberlake, S.H, Kim A, Hossain, I., Savani, R.C., and Schwartz, D.A. 2007. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease. Am J Respir Cell Mol Biol 37:248-253. [Abstract ( ]
  6. Hollingsworth, J.W., Maruok,a S., Li, Z., Potts, E.N., Brass, D.M., Garantziotis, S., Fong, A., Foster, W.M., and Schwartz, D.A. 2007. Ambient ozone primes pulmonary innate immunity in mice. J Immunol 179:4367-4375. [Abstract ( ]


  1. Garantziotis, S., Hollingsworth, J.W., Zaas, A.K., and Schwartz, D.A. 2008. The effect of toll-like receptors and toll-like receptor genetics in human disease. Annu Rev Med 59:343-359. [Abstract ( ]
  2. Garantziotis, S., Zudaire, E., Trempus, C.S., Hollingsworth, J.W., Jiang, D., Lancaster, L.H., Richardson, E., Zhuo, L., Cuttitta, F., Brown, K.K., et al. 2008. Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury. Am J Respir Crit Care Med 178:939-947. [Abstract ( ]
  3. Hollingsworth, J.W., Maruoka, S., Boon, K., Garantziotis, S., Li, Z., Tomfohr, J., Bailey, N., Potts, E.N., Whitehead, G., Brass, D.M., et al. 2008. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest 118:3462-3469. [Abstract ( ]


  1. Adair, J.E., Stober, V., Sobhany, M., Zhuo, L., Roberts, J.D., Negishi, M., Kimata, K., and Garantziotis, S. 2009. Inter-alpha-trypsin inhibitor promotes bronchial epithelial repair after injury through vitronectin binding. J Biol Chem 284:16922-16930. [Abstract ( ]
  2. Garantziotis, S., Li, Z., Potts, E.N., Kimata, K, Zhuo, L., Morgan, D.L., Savani, R.C., Noble, P.W., Foster, W.M., Schwartz, D.A., et al. 2009. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem 284:11309-11317. [Abstract ( ]
  3. Garantziotis, S., and Palmer, S.M. 2009. An unwelcome guest: Aspergillus colonization in lung transplantation and its association with bronchiolitis obliterans syndrome. Am J Transplant 9:1705-1706. [Abstract ( ]
  4. Li, Z., Garantziotis, S., Jia, W., Potts, E.N., Lalani, S., Liu, Z., He, Y.W., Foster, W.M., and Hollingsworth, J.W. 2009. The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. J Leukoc Biol 85:124-131. [Abstract ( ]


  1. Garantziotis, S., Li, Z., Potts, E.N., Lindsey, J.Y., Stober, V.P., Polosukhin, VV., Blackwell, T.S., Schwartz, D.A., Foster, W.M., and Hollingsworth, J.W. 2010. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med 181:666-675. [Abstract ( ]
  2. Garantziotis, S., and Schwartz, D.A. 2010. Ecogenomics of respiratory diseases of public health significance. Annu Rev Public Health 31:37-51 31 p following 51. [Abstract ( ]


  1. Frush, S., Li, Z., Potts, E.N., Du, W., Eu, J.P., Garantziotis, S., He, Y.W., Foster, W.M., and Hollingsworth, J.W. The Role of the Extracellular Matrix Protein Mindin in Airway Response to Environmental Airways Injury. Environ Health Perspect. [Abstract ( ]
  2. Garantziotis, S. Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value. Br J Cancer 104:542; author reply 543-544. [Abstract ( ]
  3. Heise, R.L., Stober, V., Cheluvaraju, C., Hollingsworth, J.W., and Garantziotis, S. Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity. J Biol Chem 286:17435-17444. [Abstract ( ]
  4. Martinu, T., Kinnier, C.V., Gowdy, K.M., Kelly, F.L., Snyder, L.D., Jiang, D., Foster, W.M., Garantziotis, S., Belperio, J.A., Noble, P.W., et al. Innate immune activation potentiates alloimmune lung disease independent of chemokine (C-X-C motif) receptor 3. J Heart Lung Transplant 30:717-725. [Abstract ( ]
  5. Menendez, D., Shatz, M., Azzam, K., Garantziotis, S., Fessler, M.B., and Resnick, M.A. The Toll-like receptor gene family is integrated into human DNA damage and p53 networks. PLoS Genet 7:e1001360. [Abstract ( ]
  6. Seibold, M.A., Wise, A.L., Speer, M.C., Steele, M.P., Brown, K.K., Loyd, J.E., Fingerlin, T.E., Zhang, W., Gudmundsson, G., Groshong, S.D., et al. A common MUC5B promoter polymorphism and pulmonary fibrosis. N Engl J Med 364:1503-1512. [Abstract ( ]
  7. Li Z, Potts-Kant EN, Garantziotis S, Foster WM, Hollingsworth JW. Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP. PLOS ONE 2011 6(11):e27137-. [Abstract ( ]
  8. Garantziotis S. 2011. Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value. Br J Cancer 1-4(3):542. [Abstract ( ]


  1. Ranguelova, K., Rice, A.B., Khajo, A., Triquigneaux, M., Garantziotis, S., Magliozzo, R.S., and Mason, R.P.: Formation of reactive sulfite-derived free radicals by the activation of human neutrophils: An ESR study. Free Radical Biol. Med. 52:1264-1271. 2012. [Abstract ( ]
  2. Hussain S , Al-Nsour F, Rice AB, Marshburn J, Yingling B, Ji Z, Zink JI, Walker NJ , Garantziotis S. Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes. ACS nano 6(7):5820-9. [Abstract ( ]
  3. Hussain S, Al-Nsour F, Rice AB, Marshburn J, Ji Z, Zink JI, Yingling B, Walker NJ, Garantziotis S. 2012. Cerium dioxide nanoparticles do not modulate the lipopolysaccharide-induced inflammatory response in human monocytes.. International journal of nanomedicine (7):1387-97. [Abstract ( ]
  4. Wilson RH, Maruoka S , Whitehead GS, Foley JF , Flake GP, Sever ML, Zeldin DC, Kraft M , Garantziotis S, Nakano H, Cook DN. 2012. The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens. Nature medicine 18(11):1705-10. [Abstract ( ]


  1. Li H, Edin ML, Bradbury JA, Graves JP, DeGraff LM, Gruzdev A, Cheng J, Dackor RT, Wang PM, Bortner CD, Garantziotis S, Jetten AM, Zeldin DC. Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB. American journal of respiratory and critical care medicine 2013 187(8):812-822. [Abstract ( ]
  2. Kang HS, Liao G, DeGraff LM, Bortner CD, Garantziotis S, Jetten AM. CD44 deficiency reduces the susceptibility to diet-induced adipose inflammation, hepatic steatosis, and insulin resistance. Diabetes 8(3):e58417- (2013). [Abstract ( ]
  3. Schug,TT , Johnson, AN, Balshaw DM, Garantziotis S, Walker NJ, Weis C, Nadadur, SS, Birnbaum, LS. 2013. ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials. Environmental health perspectives 121(4):410-414. [Abstract ( ]

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