Cellular & Molecular Pathology Branch

National Toxicology Program (NTP) Data and Reports Website 

Vision

To provide scientific collaboration of excellence to National Toxicology Program (NTP)  interdisciplinary research programs and DIR research using new technologies in biomedical research and to train pathology and lab animal fellows to be leaders in multidisciplinary research.

Mission

The Cellular and Molecular Pathology Branch (CMPB) conducts research on spontaneous and chemically induced lesions and the mechanisms by which they are induced. It also manages, evaluates, reviews and reports all pathology data generated during the conduct of the NTP toxicity and carcinogenicity studies. In addition, the CMPB maintains state-of the-science histology, electron microscopy, clinical pathology and special techniques core laboratories and provides diagnostic pathology support to all NIEHS investigators and the NIEHS laboratory animal colony.

CMPB is comprised of eight groups—led by Branch Chief Robert Sills, D.V.M., Ph.D., and provides the following services:

• Develops and defines in vivo and in vitro models of experimental carcinogenesis and toxicology
• Develops new methods and technologies in pathobiology
• Establishes standards, terminology and diagnostic criteria for rodent pathology
• Maintains the NTP archives and provides laboratory animal medicine support for the NTP
  • Core laboratory services including:
  • Hematology
  • Clinical chemistry
  • Histology
  • Immunohistochemistry (IHC)
  • Electron Microscopy (TEM)
  • Laser Microdissection
  • Phenotyping (Embryonic Lethality)
  • Digital Imaging/Analysis
  • Other Special Techniques – necropsy, frozen sections, & more

The Cellular & Molecular Pathology Branch is organized into seven workgroups:

• Clinical Pathology (http://www.niehs.nih.gov/research/atniehs/labs/lep/clin-path/index.cfm)
• Investigative Pathology (http://www.niehs.nih.gov/research/atniehs/labs/lep/invest-path/index.cfm)
• Molecular Pathology (http://www.niehs.nih.gov/research/atniehs/labs/lep/mole-path/index.cfm)
• NTP Laboratory Animal Management (http://www.niehs.nih.gov/research/atniehs/labs/lep/ntp-lam/index.cfm)
• NTP Pathology (http://www.niehs.nih.gov/research/atniehs/labs/lep/ntp-path/index.cfm)
• Pathology Support (http://www.niehs.nih.gov/research/atniehs/labs/lep/path-support/index.cfm)
• Special Techniques (http://www.niehs.nih.gov/research/atniehs/labs/lep/special/index.cfm)

Scientific Support Staff

Carolyn Hall
Administrative Specialist

Tel (919) 541-4995
Fax (919) 541-7666
hall7@niehs.nih.gov

Sheila Withers
Secretary

Tel (919) 541-5066
Fax (919) 541-7666
withersg@niehs.nih.gov

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