Cellular & Molecular Pathology Branch

Robert C. Sills, D.V.M., Ph.D.
Chief, Cellular & Molecular Pathology Branch, Interim Group Leader, Image Analysis Group

Tel 984-287-3839
sills@niehs.nih.gov

P.O. Box 12233

Mail Drop B3-06

Durham, N.C. 27709

Delivery Instructions

Research Summary

The Cellular and Molecular Pathology Branch (CMPB) provides toxicologic pathology leadership and laboratory animal medicine expertise to meet the goals of the National Toxicology Program and NIEHS using new technologies in biomedical research.  In addition, CMPB provides training of pathology and laboratory animal medicine fellows to be leaders in multidisciplinary research.

CMPB medical scientists and staff are responsible for the following general functions:

• Directing, managing, evaluating and interpreting all pathology data generated during the conduct of NTP toxicity and carcinogenicity studies
• Establishing standards, terminology and diagnostic criteria for rodent pathology (NTP Nonneoplastic Lesion Atlas)
• Investigating molecular mechanisms of spontaneous and chemically induced nonneoplastic and neoplastic lesions in NTP studies
• Directing the NTP laboratory animal medicine program
• Providing diagnostic pathology expertise and collaborations with NIEHS investigators and the NIEHS laboratory animal colony
• Overseeing the scientific activities of the NTP archives and frozen tissue bank
• Developing new methods/approaches and technologies in pathology and laboratory animal medicine
• Leading state-of the-science core pathology laboratories which include:
  • Hematology
  • Clinical chemistry
  • Necropsies
  • Histology
  • Immunohistochemistry
  • Electron Microscopy
  • Laser Microdissection
  • Phenotyping (Embryonic Lethality)
  • Digital Imaging/Analysis

The Cellular and Molecular Pathology Branch is organized into seven scientific groups which are led by board certified pathologists and laboratory animal medicine scientists, and fellows of the international academy of toxicologic pathologists.

• Clinical Pathology – Gregory Travlos, D.V.M.
• Molecular Pathology – Arun Pandiri, B.V.Sc., A.H., Ph.D.
• Mouse Embryo Phenotyping – Susan Elmore, D.V.M.
• NTP Laboratory Animal Medicine Program – Angela King-Herbert, D.V.M.
• NTP Pathology – David Malarkey, D.V.M., Ph.D.
• Pathology Image Analysis Group – Robert Sills, D.V.M., Ph.D. (Interim Group leader)
• Pathology Support – Ronald Herbert, D.V.M., Ph.D.

NTP Pathology Coordinator

Danica Andrews
Program Specialist

Tel 984-287-3882
Fax 919-541-0295
andrewsda@niehs.nih.gov

Scientific Support Staff

Carolyn Hall
Administrative Specialist

Tel 984-287-3849
Fax 301-480-3116
hall7@niehs.nih.gov

Sheila Withers
Secretary

Tel 984-287-3842
withersg@niehs.nih.gov