Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Office of Program Operations
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Brad Collins, M.S.P.H.
Chemist
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Tel 984-287-3121
[email protected]
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Bradley Collins is a chemist and serves as a project officer in the Office of Program Operations for the Division of Translational Toxicology (DTT). He manages contracted chemistry efforts in support of DTTtoxicology studies and has served on study design teams and interagency working groups to provide technical assistance in the areas of chemistry and toxicokinetics. Collins also provides DTT with expertise in the design, direction and interpretation of toxicokinetic studies for AIDS therapeutics and other test articles and provides cheminformatics support to medium to high throughput toxicology-screening studies for the DTT.
As a chemist, Collins is involved in the design, conduct, interpretation and reporting of DTT research and testing activities that investigate the toxicology of a variety of chemicals including high production volume chemicals, dietary supplements and nanoparticles. Over the past 35 years, Collins has served as the project officer for chemistry support activities, which include chemical procurement, characterization and toxicokinetics. As part of those activities, Collins worked with the chemistry support contractor to develop the dose analysis method validation protocol currently used by the DTT.
Collins received his B.S. in Science and Environmental Change from the University of Wisconsin-Green Bay in 1979 and his M.S.P.H. in Environmental Chemistry from the University of North Carolina at Chapel Hill in 1984. In addition to his scientific duties, he is currently serving as the Product Owner during the development DTT’s Organizational Resource and Business Information Tool (ORBIT); project management software that will allow DTT to track its research portfolio. He has also served on the DTT NICE Team, NIEHS Quality Council and the Environmental Awareness Advisory Committee.
Recent Publications
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Richard A, Tao D, LeClair C, Leister W, Tretyakov K, White E, Lewis K, Sefler A, Shinn P, Collins B, Nguyen D, Ye L, Zhao T, Xu T, Williams A, Waidyanatha S, Thomas R, Tice R, Simeonov A, Huang R. Analytical Quality Evaluation of the Tox21 Compound Library.
Chemical research in toxicology.
2025 Jan 20;38(1):15-41.
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AbstractRichard A, Tao D, LeClair C, Leister W, Tretyakov K, White E, Lewis K, Sefler A, Shinn P, Collins B, Nguyen D, Ye L, Zhao T, Xu T, Williams A, Waidyanatha S, Thomas R, Tice R, Simeonov A, Huang R. Analytical Quality Evaluation of the Tox21 Compound Library. Chemical research in toxicology. 2025 Jan 20
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Waidyanatha S, Collins B, Cristy T, Embry M, Gafner S, Johnson H, Kellogg J, Krzykwa J, Li S, Mitchell C, Mutlu E, Pickett S, You H, Van Breemen R, Baker T. Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2024 Apr;186:114537.
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AbstractWaidyanatha S, Collins B, Cristy T, Embry M, Gafner S, Johnson H, Kellogg J, Krzykwa J, Li S, Mitchell C, Mutlu E, Pickett S, You H, Van Breemen R, Baker T. Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Apr
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Hamm J, Hsieh J, Roberts G, Collins B, Gorospe J, Sparrow B, Walker N, Truong L, Tanguay R, Dyballa S, Miñana R, Schiavone V, Terriente J, Weiner A, Muriana A, Quevedo C, Ryan K. Interlaboratory Study on Zebrafish in Toxicology: Systematic Evaluation of the Application of Zebrafish in Toxicology's (SEAZIT's) Evaluation of Developmental Toxicity.
Toxics.
2024 Jan 22;12(1):.
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AbstractHamm J, Hsieh J, Roberts G, Collins B, Gorospe J, Sparrow B, Walker N, Truong L, Tanguay R, Dyballa S, Miñana R, Schiavone V, Terriente J, Weiner A, Muriana A, Quevedo C, Ryan K. Interlaboratory Study on Zebrafish in Toxicology: Systematic Evaluation of the Application of Zebrafish in Toxicology's (SEAZIT's) Evaluation of Developmental Toxicity. Toxics. 2024 Jan 22
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Smith-Roe S, Swartz C, Rashid A, Christy N, Sly J, Chang X, Sipes N, Shockley K, Harris S, McBride S, Larson G, Collins B, Mutlu E, Witt K. Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays.
Environmental and molecular mutagenesis.
2023 Apr;64(4):202-233.
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AbstractSmith-Roe S, Swartz C, Rashid A, Christy N, Sly J, Chang X, Sipes N, Shockley K, Harris S, McBride S, Larson G, Collins B, Mutlu E, Witt K. Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays. Environmental and molecular mutagenesis. 2023 Apr
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Auerbach S, Ballin J, Blake J, Browning D, Collins B, Cora M, Fernando R, Fostel J, Liu Y, Luh J, Machesky N, Prince L, Roberts G, Shipkowski K, Silinski M, Skowronek A, Sparrow B, Toy H, Waidyanatha S, Watson A. NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Perfluorohexanesulfonamide (CASRN 41997-13-1) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): NIEHS Report 10
NIEHS Report Series.
2023 Mar [Epub ahead of print].
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AbstractAuerbach S, Ballin J, Blake J, Browning D, Collins B, Cora M, Fernando R, Fostel J, Liu Y, Luh J, Machesky N, Prince L, Roberts G, Shipkowski K, Silinski M, Skowronek A, Sparrow B, Toy H, Waidyanatha S, Watson A. NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Perfluorohexanesulfonamide (CASRN 41997-13-1) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): NIEHS Report 10 NIEHS Report Series. 2023 Mar
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