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Your Environment. Your Health.

NIEHS Teleconference, October 25: Mouse DNA to Aid Biomedical Research

National Institute of Environmental Health Sciences (NIEHS)

News Release

Monday, October 23, 2006, 12:00 p.m. EDT
Contact: Robin Mackar, NIEHS

Will Help Discover Why Some People Are Susceptible to Certain Diseases

Researchers have successfully sequenced the DNA of 15 mouse strains most commonly used in biomedical research. More than 8.3 million genetic variations, or single nucleotide polymorphisms (SNPs), were discovered among the genomes of the 15 mouse strains, and the data are now available on a public website. These new data on laboratory mice will help researchers better understand what makes some individuals more susceptible than others to certain diseases, and will serve as a valuable resource as researchers determine the role that various environmental substances may play in the development of disease.

The "Re-sequencing and SNP Discovery Project" led by the National Institute ofEnvironmental Health Sciences (NIEHS), part of the National Institutes of Health, and itsNational Toxicology Program, began less than two years ago with a $13 million budget. The work was completed by Perlegen Sciences, Inc. and the data are available on the National Center for Biotechnology Information website at ( .

  • David A. Schwartz, M.D., Director, National Institute of Environmental Health Sciences and National Toxicology Program
  • Kelly Frazer, Ph.D., Vice President of Genomics Perlegen Sciences, Inc.
  • David Threadgill, Ph.D., Associate Professor, Department of Genetics University of North Carolina
  • David Christiani, M.D., Professor of Occupational Medicine and Epidemiology, Environmental Health and Epidemiology, Harvard School of Public Health
WHAT:   Teleconference with NIEHS Director and leading scientific experts

WHEN:   Wednesday, October 25, 1:00 p.m. EDT

WHERE:   Teleconference call. Reporters to dial in call: 877-707-9631
International Reporters, call 785-832-0301
Password: NIEHS

Reporters please call Robin Mackar, 984-287-3355, to reserve your phone line or for further assistance.

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