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Upcoming Distinguished Lecturer

By Eddy Ball
March 2007

Peter Jones
Distinguished Guest Lecturer Peter Jones (Photo courtesy of the University of Southern California)

University of Southern California (USC) Distinguished Professor Peter Jones, Ph.D., will deliver the next talk in the 2006-2007 NIEHS Distinguished Lecture Series at 11:00 a.m. on March 13 in Rodbell Auditorium. Jones is director of the USC/Norris Comprehensive Cancer Center and holds the H. Leslie Hoffman and Elaine S. Hoffman Chair in Cancer Research. He will speak on "How the Epigenome Changes in Cancer."

Jones' laboratory studies of DNA methylation in human cancer focus on the biochemical mechanisms by which cytosine methylation patterns are changed. His lab is particularly interested in these changes with respect to the cell cycle and seeks to determine how this process is involved in the transformation of human cells. Jones is working to understand fundamental aspects of the control of DNA methylation as it relates to the de novo methylation of the promoter regions of tumor suppressor genes. This epigenetic mechanism by which tumor suppressor genes can be inactivated may be an important pathway which contributes to carcinogenesis in a wide variety of tumors.

Laboratory of Molecular Carcinogenesis Chief Trevor Archer, Ph.D., is host of the lecture.

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