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Upcoming Distinguished Lecturer

By Eddy Ball
April 2007

C. David Allis
Distinguished Lecturer C. David Allis (Photo courtesy of The Rockefeller University)

C. David Allis, Ph.D. will deliver the next talk in the 2006-2007 NIEHS Distinguished Lecture Series at 2:00 p.m. on April 10 in Rodbell Auditorium. Allis is the Joy and Jack Fishman Professor and Head of the Laboratory of Chromatin Biology at The Rockefeller University in New York. His lecture is titled "Beyond the Double Helix: Reading and Writing the Histone Code."

According to Allis' online account of his research, his laboratory has postulated that "an epigenetic indexing system for the genome works as a fundamental regulatory mechanism in addition to the DNA and the genetic information itself." This research is centered on the hypothesis that "distinct covalent histone modifications, acting alone, sequentially or in combination, form a 'histone code' that is then read by effector proteins to bring about distinct downstream events." Allis' goal is to understand better the dysfunctional processes leading to tumor formation.

Laboratory of Molecular Carcinogenesis Chief Trevor Archer, Ph.D., is host of the lecture.

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