Cancer
Description
Cancer arises when cells are unable to repair DNA damage and experience abnormal cell growth and division. The process known as metastasis occurs when cancer cells travel to other parts of the body via the bloodstream and replace normal tissue. According to the American Cancer Society, this chronic disease is the second leading cause of death in the U.S. with half of all men and one-third of all women developing some form of cancer during their lifetimes.
Although cancer is responsible for 23% of all deaths in the U.S., millions of Americans have recovered from the disease. People may reduce their chances of getting cancer by employing prevention methods such as having regular screenings and living a healthy lifestyle.
The NIEHS is committed to understanding the connection between genetics and environmental exposures with regard to cancer. In addition to several Division of Intramural Research (DIR) groups studying the molecular mechanisms behind the disease, the NIEHS funds cancer research at other institutions.
What NIEHS is Doing on Cancer
- Obesity primes the colon for cancer (http://www.niehs.nih.gov/news/newsletter/2014/4/science-obesity/index.htm)
- New study links BPA and prostate cancer in humans (http://www.niehs.nih.gov/news/newsletter/2014/4/science-bpaprostate/index.htm)
- Osteoporosis drug may treat breast and liver cancers (http://www.niehs.nih.gov/news/newsletter/2014/4/science-osteoporosisdrug/index.htm)
- Capitol Hill events put spotlight on environmental connections to cancer (http://www.niehs.nih.gov/news/newsletter/2013/10/spotlight-birnbaumcapitol/index.htm)
- Study links tanning gene to increase risk of testicular cancer (http://www.niehs.nih.gov/news/newsletter/2013/10/science-testicular/index.htm)
- 12th Report on Carcinogens (RoC)
- A Human Health Perspective on Climate Change (Full Report) (4MB)
- Acrylamide (1MB)
- Addressing New Challenges in Children’s Environmental Health (259KB)
- Aristolochic Acids (229KB)
- Certain Glass Wool Fibers (Inhalable) (575KB)
- Child Development and Environmental Toxins (585KB)
- DNA Replication Fidelity: DNA Damage & Repair
- Formaldehyde (373KB)
- Getz uncovers exciting new trends in cancer genomes (http://www.niehs.nih.gov/news/newsletter/2012/11/science-getz/index.htm)
- Ginkgo (442KB)
- High-throughput Screening Finds Surprising Properties for Antioxidants (http://www.niehs.nih.gov/news/newsletter/2012/4/science-highthroughput/index.htm)
- In Small Doses: Arsenic - a 10 min. video about the risks of arsenic exposure in private well water
- Laboratory of Molecular Carcinogenesis
- Molecular Endocrinology: Glucocorticoid Receptors and the Immune System
- National Toxicology Program: Report on Carcinogens (RoC)
- New Substances Added to HHS Report on Carcinogens
- NTP panel reviews outcomes of women treated for cancer while pregnant (http://www.niehs.nih.gov/news/newsletter/2012/11/science-ntp/index.htm)
- Of Mice and Women: Modeling Breast Cancer and the Environment - Scientific Glossary (PDF)
- Profile: Report on Carcinogens: Captafol
- Profile: Report on Carcinogens: Cobalt-Tungsten Carbide: Powders & Hard Metals
- Profile: Report on Carcinogens: o-Nitrotolulene
- Profile: Report on Carcinogens: Riddelliine
- Programs and Initiatives: Climate Change and Human Health
- Questions and Answers About the 12th Edition Report on Carcinogens
- Report on Carcinogens - 12th Edition, The (262KB)
- Statement on the Report on Carcinogens (73KB)
- Study Suggests Nutritional Supplements Could One Day Prevent Skin Cancer (http://www.niehs.nih.gov/news/newsletter/2011/september/science-supplements/index.cfm)
- Styrene (248KB)
- Understanding the Links between Environmental Exposures and Cancer
General Information
- Cancer
- Cancer.gov - The National Cancer Institute's portal to information on the types of cancer, treatment options, methods for coping with cancer, support groups, screening and testing and prevention measures.
- Cancer and the Environment (699KB)
- Cancer News on the Net - Dedicated to bringing patients and their families the latest news and information on cancer diagnosis, treatment and prevention.
- CDC Tips from Former Smokers Campaign (Tips): A national campaign to help people quit smoking
- Gene Toxicity and Cancer
- Household Products Database: Health Effects
- Oceans of Discovery: How the Study of Oceans Can Improve Human Health (994KB)
- Oncology Research Links
- OncoLink - Good starting resource for information on the types of cancer, treatment options, coping with cancer, clinical trials, and bibliography of books, music and videotapes on cancer.
- Talking Glossary of Genetic Terms: Apoptosis
- Talking Glossary of Genetic Terms: Cancer
- Talking Glossary of Genetic Terms: Complex Disease
- Talking Glossary of Genetic Terms: Carcinogen
- Talking Glossary of Genetic Terms: Tumor Suppressor Gene
- Talking Glossary of Genetic Terms: Mutation
- Talking to Your Doctor - Resources from NIH
- The Interagency Working Group on Climate Change and Health (1MB)
