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Your Environment. Your Health.

Staff Scientist, National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicologic Methods (NICEATM)

Staff Scientist
Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Toxicology Program (NTP)
Interagency Center for the Evaluation of Alternative Toxicologic Methods (NICEATM)
Research Triangle Park, North Carolina

The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicologic Methods (NICEATM) in the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, North Carolina is recruiting a Staff Scientist under the leadership of Nicole Kleinstreuer, PhD. NICEATM provides scientific support to Division of the National Toxicology Program (DNTP) via interactions with the various DNTP offices and branches, including the Tox21 efforts. As its primary function, NICEATM provides scientific and administrative support to the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), ensures compliance with all statutory duties of the ICCVAM, and develops and validates improved toxicology methods as detailed in the ICCVAM strategic roadmap.

We are seeking an experienced scientist with a speciality in nonanimal alternatives and in vitro testing strategies, with a strong background in toxicology, physiology, molecular biology, and/or related biological science disciplines, as well as principles used for chemical and safety hazard evaluations and risk assessment. A successful candidate will have knowledge of environmental factors capable of adversely affecting human health as well as experience with model systems for predicting human health effects, such as microphysiological systems, organotypic cultures, stem cell based approaches, and ‘omics technologies. Knowledge of the goals and activities of NICEATM and its working relationship with ICCVAM, DNTP, NIEHS, NIH, and other federal agencies is desired, as well as experience working with NGOs, chemical industry scientists, and research organizations. Besides being a scientifically active and established scientist, the ideal candidate must be skilled in oral and written communication, and possess leadership skills and demonstrated ability to mentor multidisciplinary staff. Experience in preparing written materials and providing advice and consultation to both technical and non-technical personnel, in particular to support regulatory decision making (e.g. participation in scientific advisory commitees or validation management groups), is desired. Scientific expertise in DNTP focal areas such as developmental neurotoxicity or cancer, systematic review processes, and/or gene-environment interactions, as demonstrated by peer-reviewed publications and invited presentations, would be beneficial. A successful candidate is expected to lead, develop, manage, and coordinate scientific and operational activities related to the development, validation, and use of proposed nonanimal testing methods; develop strategies with appropriate programmatic, interagency, and international committees and organizations; and will represent DNTP and ICCVAM at national and international scientific workshops and meetings, including potential travel for in-person participation (up to 25% of work schedule) or virtual participation as appropriate.

A Staff Scientist is an NIH employee generally appointed to a time-limited, renewable position to support the long-term projects of a research program. Staff Scientists do not receive independent resources, although they often work autonomously and have sophisticated skills and knowledge essential to the work of the laboratory. Staff Scientists should be capable of personally designing experiments, but generally do not have responsibilities for initiating new research programs. The Staff Scientist in this position will conduct independent research and mentor trainees and other laboratory staff.

Qualifications: Applicants must have a Ph.D., D.V.M., Sc.D., M.D., or equivalent in toxicology or related fields, with at least 5 years of research experience after receiving the final degree, such as postdoctoral research and/or equivalent experience in their field. Applicants must demonstrate experience in in vitro human cell-based methods, organotypic systems, developing integrated testing strategies, and regulatory application and translation. Experience with international consortiums and organizations such as the OECD is also desired. An outstanding comprehension of the relevant literature in the aforementioned areas and related fields as well as excellent oral and written communication skills are required. Priority will be given to applicants with demonstrated ability to foster effective scientific collaborations across disciplines, and to create an atmosphere for maximum creativity, productivity, and cooperation.

Salary/benefits: This is a federal full-time equivalent position, and a comprehensive benefits package is available. Salary will be commensurate with experience and qualifications.

How to apply: To submit a complete application package, interested candidates must submit their full curriculum vitae including bibliography and a 3- to 4-page statement of research experience and interests, as ONE (1) combined PDF to Please include vacancy number NR125 and your name in the subject line of your email submission. Please include in your CV a description of mentoring and outreach activities, especially those involving women or other underrepresented groups in biomedical research. In addition, applicants must arrange to have three (3) letters of recommendation sent to Please be sure that referees include your name and Vacancy Number NR125 in the subject line of their email. For further information about the position, please contact Dr. Nicole Kleinstreuer. Incomplete applications or paper applications will not be accepted. Review of applications will begin on June 3, 2021.

Commitment to Diversity and Equal Employment Opportunity: NIH NIEHS encourages the application and nomination of qualified women, minorities, and individuals with disabilities. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factors. NIH NIEHS will provide reasonable accommodations to applicants with disabilities as appropriate. If you require reasonable accommodation during any part of the application and hiring process, please notify us.

Foreign Education: Applicants who have completed part or all of their education outside of the United States must provide an evaluation by an accredited organization to ensure its equivalence to education received in accredited educational institutions in the United States. For more information on foreign education verification, visit the National Association of Credential Evaluation Services (NACES). Verification must be received prior to the effective date of the appointment.

The NIH is the premier biomedical research center for the world. Its 27 institutes and centers employ more than 21,000 employees doing a vast array of jobs, all supporting efforts for a healthy nation. For information about the NIH mission, goals and institutes and centers, visit About NIH.

Do not include your birth date, photograph, or social security number (SSN) on application materials. DHHS and NIH are equal opportunity employers.

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