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Your Environment. Your Health.

Staff Scientist 1, Office of Program Operations, Division of Translational Toxicology

Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Division of Translational Toxicology (DTT)
Office of Program Operations (OPO)
Research Triangle Park, North Carolina

NIEHS is seeking a dynamic, highly motivated Title 42(g) Staff Scientist 1 in support of the Office of Program Operations (OPO), within the Division of Translational Toxicology (DTT), formerly Division of National Toxicology Program (DNTP), at the National Institute of Environmental Health Sciences (NIEHS). DTT is a team-based scientific organization, and its mission is to improve public health through development of data and knowledge that are translatable, predictive, and timely. Much of the work carried out by DTT is in support of the National Toxicology Program, an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Staff scientists in DTT work in multidisciplinary teams and collaboratively with scientists in other fed-eral agencies, institutes, industry, and academia. In addition to scientific research, Staff Scientists occu-py a critical place servicing varying levels of intramural science providing laboratory and facility man-agement, technical support and innovation, and managerial, administrative, and other mission support activities.


May include but are not limited to:

  1. Conceptualize, develop, implement, and coordinate scientific and operational activities related to chemistry and absorption, distribution, metabolism, excretion, and toxicokinetics (ADME/TK) in support of hazard characterization of xenobiotics (e.g., environmental chemicals and mixtures) of concern to adverse human health.
  2. Provide direction for scientific activities (e.g., chemistry, ADME/TK) performed by contract research organization(s) in support of DTT research, following receipt of appropriate training and certification in government contract management.
  3. Collaborate with federal partners, other organizations, and stakeholders to develop coordinated research strategies.
  4. Represent DTT and NIEHS at national and international scientific workshops and meetings.
  5. Engage with senior management and in public forums, foster stakeholder engagement, delegate responsibilities to contractors, individuals, and teams and monitor progress to all facets of plan.
  6. Promote continuous skill and professional development of employees, identify knowledge and skill gaps, provide constructive feedback and facilitative mentorship.
  7. Contribute to proactive technical and business operation practices, recommending cutting-edge and best practices for process improvement.


The ideal candidate for this position will have:

  1. Ph.D. or equivalent doctoral degree (e.g., Sc.D., Pharm.D.) in chemistry or a related field and preferably an early-to-mid career candidate.
  2. Experience and training in management of multiple complex projects.
  3. Experience in use of state-of the-art analytical chemistry approaches to understand xenobiotic exposures (e.g., exposomics) and their potential to alter biological pathways (e.g., metabolom-ics) that can lead to adverse health outcomes.
  4. Experience in the conduct and evaluation of in silico, in vitro, and in vivo ADME/TK studies to enable translation of animal toxicology study data to determine the potential for adverse human health effects of xenobiotics.
  5. Recognition as a scientifically active and respected expert (e.g., as evidenced by publications and, presentations, honors, awards, elected positions in professional societies, invited reviewer for journals).
  6. Strong oral and written communication skills, as well as excellent interpersonal, negotiation and facilitation skills.
  7. Ability to innovate and work in a team-based multi-disciplinary organization.
  8. Ability to provide advice and consultation to both technical and non-technical personnel.

It is preferred that the candidate reside within the local commuting area of Research Triangle Park, North Carolina. This position is not eligible for remote work. At the supervisor’s discretion, this position may offer work schedule flexibilities, including telework.

As a NIH Title 42(g) Staff Scientist 1, the employee is generally appointed to a time-limited, renewable position. Staff Scientists do not receive independent resources as a principal investigator, although they will often work independently and have sophisticated skills and knowledge essential to the work of the branch.


This is a federal full-time equivalent position, and a comprehensive benefits package is available. Salary will be commensurate with experience, qualifications, and accomplishments.

How to Apply:

Applications for the position are accepted from July 11, 2023 through August 11, 2023. Interested candidates must submit materials as one combined PDF via email to Bonnie J. Earnhardt. Include the vacancy number (NR148) in the subject line.

  1. Complete application materials must be combined as one PDF document and include:
    • Letter of Interest and Research Statement – Maximum four-page statement of interest, vision, research experience, and commitment to organizational diversity, equity, inclusion, and accessi-bility (DEIA), mentoring and outreach activities involving underrepresented groups and building a work culture where everyone is treated with dignity and respect.
    • Curriculum Vitae – Curriculum vitae with full bibliography, including examples of scientific recognition (e.g., awards, honors, and activities).
  2. Separately, arrange to have a minimum of two letters of reference. Reference letters from individuals in the scientific/academic community who are familiar with the candidate’s accomplish-ments, motivation, and skills (within one year of application). Letters must be signed by the letter writer and submitted by e-mail. Ensure references include the applicant’s name and vacancy number NR148 in the email subject line sent to Intramural Applications. If reference letters were written in advance of the application and are within one year of application, the applicant may include these as part of the materials included in the one PDF submitted, rather than submitting them separately by the letter writer.

Note: Incomplete applications will not be considered. For more information about the position, contact Dr. David M. Crizer.

Commitment to Diversity and Equal Employment Opportunity:

NIH/NIEHS encourages the application and nomination of qualified women, minorities, and individuals with disabilities. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factors. NIH/NIEHS will provide reasonable accommodations to applicants with disabilities as appropriate. If you require reasonable accommodation during any part of the application and hiring process, please notify us.

Equal Opportunity Employment:

Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities.

Foreign Education:

Applicants who have completed part or all their education outside of the US must have their foreign education evaluated by an accredited organization to ensure that the foreign education is equivalent to education received in accredited educational institutions in the United States. We will only accept the completed foreign education evaluation. For more information on foreign education verification, visit the . Verification must be received prior to the effective date of the appointment.

NIH is the premier biomedical research center for the world. Its 27 institutes and centers employ more than 18,000 employees doing a vast array of jobs, all supporting efforts for a healthy nation. For information about the NIH mission, goals and institutes and centers, visit .



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