Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Division of Translational Toxicology (DTT)
Research Triangle Park, North Carolina

NIEHS is seeking a dynamic, highly motivated scientist to serve as a Title 42 (f) Senior Scientist and chief of the Systems Toxicology Branch (STB), in the Division of Translational Toxicology (DTT), formerly the Division of the National Toxicology Program, at NIEHS. The mission of the DTT is to evaluate environmental substances of public health concern by developing and applying tools of modern toxicology and molecular biology. The DTT provides critical data for regulatory and non-regulatory stakeholder decision making to protect human health using rodent studies, alternative in vivo model systems, in vitro high-throughput screens and/or computational approaches to gauge the potential of thousands of substances to perturb biological targets and pathways.

The scientific goals of the DTT are achieved through a distinct and highly cooperative and integrated team science operational model whereby scientific staff across multiple branches in the DTT assemble into interdisciplinary project teams and utilize centrally managed shared resources, in contrast to the traditional NIH principal investigator-led research group model. Most of the research is carried out through use of external research and development contracts together with a limited amount of onsite intramural laboratory research capability. The governance of projects that use DTT resources are centrally approved by management.

The STB chief oversees all major functions of the DTT organizational unit principally responsible for design, oversight, interpretation, and reporting of traditional toxicology and carcinogenesis studies. The STB chief is responsible for continuous improvement and innovation in how the capabilities of the STB are applied to contemporary and human-relevant public health challenges.

The STB chief also leads and otherwise contributes to DTT multidisciplinary teams conceiving, developing, designing, interpreting, and reporting toxicology, carcinogenicity, and other applied and basic science research activities. These activities are highly diverse including in vitro and in vivo evaluations of the potential health impact of consumer products, medicinal herbs, pharmaceuticals, and occupational chemical exposures, biological contaminants, and novel substances such as nanoscale materials. In DTT, multidisciplinary teams and senior leaders partner with toxicologists, chemists, pathologists, specialists in metabolism and kinetics, as well as experts in genetic toxicity, in vitro screening and molecular modeling to design research programs tailored to the issues presented by individual substances or mixtures under study.

The STB chief will contribute to leadership of the DTT by partnering with the scientific director and other branch and office leadership to provide strategic direction, manage fiscal and workforce resources and to ensure deliberate and timely advancement of the scientific portfolio. The successful candidate will demonstrate a strong commitment to strategic planning, leadership and workforce development. It is preferred that the branch chief reside within commuting distance of Research Triangle Park to be available for personally engaging and mentoring staff and for building relationships with the DTT leadership and others in the DTT/NIEHS, with the option to telework as needed.

The successful applicant will be an innovative thinker, possess a strong foundational scientific knowledge in an area of toxicology, and demonstrate a working knowledge of carcinogenesis, genomics, molecular biology, molecular genetics, cellular biology, systems biology, pathology, and statistics. The applicant should be recognized for his/her scientific expertise within the national and international scientific community. The applicant will have demonstrated a commitment to applied and translational research with unique insights into how to build trust with decision-making stakeholders. The successful applicant will have demonstrated experience leading diverse scientific research programs and teams, including multi-institutional programs, and participation in national and international consortia.

The ideal candidate will have a research-based professional degree (Ph.D., M.D., Pharm.D., D.V.M., or equivalent) in the life sciences, with extensive experience in in vivo toxicology and carcinogenesis studies carried out according to national and international guidelines. The successful candidate must demonstrate the strategic and visionary leadership for identifying and matching new scientific technologies with the needs of the DTT, while also understanding the limitations of data generated through these approaches for public health decision-making.

It is preferred that the branch chief reside within the local commuting area of Research Triangle Park, North Carolina. This position is not eligible for remote work. At the supervisor’s discretion, this position may offer work schedule flexibilities, including telework.

Appointees may be a US citizen, Legal Permanent Resident or non-US citizen who are eligible for a valid work authorization.

This position is subject to a background investigation.

Salary/Benefits: This is a federal full-time equivalent position, and a comprehensive benefits package is available. Salary will be commensurate with experience, qualifications, and accomplishments.

How to Apply: Applications for this position will be accepted from Monday, June 10, 2024 through Wednesday, July 10, 2024. To submit a complete application package, interested candidates must submit a full curriculum vitae including bibliography, a three to four-page statement of research experience and interests, and a one-page statement addressing commitment to diversity, equity, inclusion, and accessibility (DEIA). Application materials must be submitted as a PDF to Bonnie Earnhardt at [email protected]. Please include vacancy number AC1453 and applicant’s name in the subject line of the submission email. In addition, applicants must arrange to have three (3) letters of recommendation sent to [email protected]. Letters should be on official letterhead and signed. Ensure references include the applicant’s name and vacancy number AC1453 in the subject line of their email. For further information about the position, please contact Dr. Robert Sills at [email protected]. Incomplete applications or paper applications will not be accepted.

Commitment to Diversity and Equal Employment Opportunity:
The NIH NIEHS encourages the application and nomination of traditionally underrepresented groups in the sciences, including women, minorities, and individuals with disabilities. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factors. NIH NIEHS will provide reasonable accommodations to applicants with disabilities, as appropriate. If reasonable accommodation is required during any part of the application and hiring process, please notify us.

Foreign Education:
Applicants who have completed part or all their education outside of the United States must provide an evaluation by an accredited organization to ensure its equivalence to education received in accredited educational institutions in the United States. For more information on foreign education verification, visit the National Association of Credential Evaluation Services (NACES) website at http://www.naces.org/. Verification must be received prior to the effective date of the appointment.

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