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Your Environment. Your Health.

Selected Scientific Advances

2012 - 2017 Strategic Plan

Citation Year Goal
Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P. 2015. Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry. Mol Cell 59(2):176-87. [Abstract] 2015 Goal 1
Chrysovergis K (DIR), X Wang (DIR), J Kosak (DIR), SH Lee, J Sik Kim (DIR), JF Foley (NTP), G Travlos (NTP), S Singh (DIR), S Joon Baek and TE Eling(DIR). 2014. NAG-1/GDF15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes (Lond) 38:1555-1564. [Abstract] 2014 Goal 1
Shaughnessy DT (DERT), McAllister K (DERT), Worth L (DERT), Haugen AC (DERT), Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC (NTP), Tice RR (NTP), Balshaw DM (DERT), Tyson FL (DERT). 2014. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect 122(12):1271-8. [Abstract] 2014 Goal 1
Gosavi RA (DIR), Knudsen GA, Birnbaum LS (OD), Pedersen LC (DIR). 2013. Mimicking of estradiol binding by flame retardants and their metabolites: a crystallographic analysis. Environ Health Perspect. 121(10):1194-9. [Abstract] 2014 Goal 1
Liu C, Peng J, Matzuk MM, Yao HH (DIR). 2015. Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells. Nat Commun 6:6934. [Abstract] 2015 Goal 1
Markunas CA (DIR), Xu Z (DIR), Harlid S (DIR), Wade PA (DIR), Lie RT, Taylor JA (DIR), Wilcox AJ (DIR). 2014. Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy. Environ Health Perspect 122(10):1147-1153. [Abstract] 2014 Goal 1
Deroo LA, SC Bolick, Z Xu, DM Umbach, D Shore, CR Weinberg, DP Sandler and JA Taylor. 2013. Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study. Carcinogenesis 35(2):333-338. [Abstract] 2014 Goal 1
Davis FM (DIR), A Janoshazi (DIR), KS Janardhan, N Steinckwich (DIR), DM D'Agostin (DIR), JG Petranka (DIR), PN Desai (DIR), SJ Roberts-Thomson, GS Bird (DIR), DK Tucker (NTP), SE Fenton (NTP), S Feske, GR Monteith and JW Putney, Jr. (DIR). 2015. Essential role of Orai1 store-operated calcium channels in lactation. Proc. Natl. Acad. Sci. U. S. A. 112(8):5827-5832. [Abstract] 2015 Goal 1
Tyler CR, Hafez AK, Solomon ER, Allan AM. 2015. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol 288(1):40-51. [Abstract] 2015 Goal 1
Hewitt SC (DIR), Winuthayanon W (DIR), Pockette B (DIR), Kerns RT (DIR), Foley JF (NTP), Flagler N (NTP), Ney E (NTP), Suksamrarn A, Piyachaturawat P, Bushel PR (DIR) and Korach KS (DIR). 2015. Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice. Environ Health Perspect 123(4):344-352. [Abstract] 2015 Goal 1
Chen S, JH Hsieh (NTP), R Huang, S Sakamuru, LY Hsin, M Xia, KR Shockley (DIR), S Auerbach (NTP), N Kanaya, H Lu, D Svoboda (NTP), KL Witt (NTP), BA Merrick (NTP), CT Teng (NTP) and RR Tice (NTP). 2015. Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library. Toxicol. Sci 147(2):446-457. [Abstract] 2015 Goal 1
Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese S, Markunas CA, Richmond RC, Xu C-J, Kupers LK, Oh SS, Hoyo C, Gruzieva O, Soderhall C, Salas LA, Baiz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Haberg SE, Xu Z, van Meurs JB, Gant TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergstrom A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles M-A, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert M-F, Eskenazi B, Vrijheid M, Arshad H, Anto JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchand EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VWV, Wilcox A, Melen E, London SJ. 2016. DNA methylation in newborns and maternal smoking in pregnancy: Genome-wide consortium meta-analysis. Am J Hum Genet 98(4):680-696. [Abstract] 2015 Goal 1
Behl M (DNTP), Hsieh JH, Shafer TJ, Mundy WR, Rice JR (DNTP), Boyd WA (DNTP), Freedman JH (DNTP-former), Hunter ES, Jarema K, Padilla S (DNTP), Tice RR (DNTP). 2015. Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. Neurotoxicol Teratol 52(Pt B):181-93. [Abstract] 2015 Goal 1
Bhusari, S, Pandiri, AR (DNTP), Nagai, H, Wang, Y, Foley, J (DNTP), Hong, HL (DNTP), Ton, TV (DNTP), DeVito, M (DNTP), Shockley, KR, Peddada, SD, Gerrish, KE, Malarkey, DE (DNTP), Hooth, MJ (DNTP), Sills, RC (DNTP), Hoenerhoff, MJ (DNTP). 2015. Genomic profiling reveals unique molecular alterations in hepatoblastomas and adjacent hepatocellular carcinomas in B6C3F1 mice. Toxicol Pathol 43(8):1114-1126. [Abstract] 2015 Goal 1
Yang J(DIR), Bennett BD(DIR), Luo S, Inoue K(DIR), Grimm SA(DIR), Schroth GP, Bushel PR(DIR), Kinyamu HK(DIR), Archer TK (DIR). 2015. LIN28A Modulates Splicing and Gene Expression Programs in Breast Cancer Cells. Mol Cell Biol 35(18):3225-43. [Abstract] 2015 Goal 1
Freudenthal BD (DIR), Beard WA (DIR), Cuneo MJ, Dyrkheeva NS (DIR), Wilson SH (DIR). 2015. Capturing snapshots of APE1 processing DNA damage. Nat Struct Mol Biol 22(11):924-31. [Abstract] 2015 Goal 1
Boyd, WA (DNTP), Smith, MV, Co, CA, Pirone, JR, Rice, JR (DNTP), Shockley, KR, Freedman, JH (DNTP-former). 2015. Developmental Effects of the ToxCast™ Phase I and II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits. Environ Health Perspect 124(5):586-593. [Abstract] 2015 Goal 1
Sen A, Heredia N, Senut MC, Land S, Hollocher K, Lu X, Dereski MO, Ruden DM. 2015. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren. Sci Rep 5:14466. [Abstract] 2015 Goal 1
Bell MR, Hart BG, Gore AC. 2016. Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 2. Sex-specific neuromolecular effects in the brain. Mol Cell Endocrinol 420:125-37. [Abstract] 2016 Goal 1
Reese SE (DIR), S Zhao (DIR), MC Wu, BR Joubert (DERT), CL Parr (DIR), SE Haberg, PM Ueland, RM Nilsen, O Midttun, SE Vollset, SD Peddada (DIR), W Nystad and SJ London (DIR). 2016. DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy. Environ Health Perspect 125(4):760-766. [Abstract] 2016 Goal 1
Kang HS (DIR), Y Takeda (DIR), K Jeon (DIR) and AM Jetten (DIR). 2016. The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells. PLoS One 11(6):e0157138 [Abstract] 2016 Goal 1
Markunas CA (DIR), AJ Wilcox (DIR), Z Xu (DIR), BR Joubert (DIR), S Harlid (DIR), V Panduri (DIR), SE Haberg, W Nystad, SJ London (DIR), DP Sandler (DIR), RT Lie, PA Wade (DIR) and JA Taylor (DIR). 2016. Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults. PLoS ONE 11(7):e0156361 [Abstract] 2016 Goal 1
Kang HS (DIR), LY Chen (DIR), K Lichti-Kaiser (DIR), G Liao (DIR), K Gerrish (DIR), CD Bortner (DIR), HH Yao (DIR), EM Eddy (DIR) and AM Jetten (DIR). 2016. Transcription Factor GLIS3: a New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis. Stem Cells 34(11):2772-2783. [Abstract] 2016 Goal 1
Paquette AG, Houseman EA, Green BB, Lesseur C, Armstrong DA, Lester B, Marsit CJ. 2016. Regions of variable DNA methylation in human placenta associated with newborn neurobehavior. Epigenetics. 11(8):603-13. [Abstract] 2016 Goal 1
Krakowiak P, Walker CK, Tancredi D, Hertz-Picciotto I, Van de Water J. 2016. Autism-specific maternal anti-fetal brain autoantibodies are associated with metabolic conditions. Autism Res 10(1):89-98. [Abstract] 2016 Goal 1
Ma H, O'Farrell PH. 2016. Selfish drive can trump function when animal mitochondrial genomes compete. Nat Genet. 48(7):798-802. [Abstract] 2016 Goal 1
Morgan, DL (DNTP), Jokinen, MP, Johnson, CL, Price, HC, Gwinn, WM (DNTP), Bousquet, RW, Flake, GP (DNTP). 2016. Chemical reactivity and respiratory toxicity of the alpha-diketone flavoring agents: 2,3-butanedione, 2,3-pentanedione, and 2,3-hexanedione. Toxicol Pathol 44(5):763-783. [Abstract] 2016 Goal 1
Nayak AP, Green BJ, Lemons AR, Marshall NB, Goldsmith WT, Kashon ML, Anderson SE, Germolec DR (DNTP), Beezhold DH. 2016. Subchronic exposures to fungal bioaerosols promotes allergic pulmonary inflammation in naive mice. Clin Exp Allergy 46(6):861-70. [Abstract] 2016 Goal 1
Swartley, OM, Foley, JF (DNTP), Livingston, DP, 3rd, Cullen, JM, Elmore, SA (DNTP). 2016. Histology atlas of the developing mouse hepatobiliary hemolymphatic vascular system with emphasis on embryonic days 11.5-18.5 and early postnatal development. Toxicol Pathol 44(5):705-725. [Abstract] 2016 Goal 1
Schellenberg MJ (DIR), L Perera (DIR), CN Strom, CA Waters, B Monian (DIR), CD Appel (DIR), CK Vilas (DIR), JG Williams (DIR), DA Ramsden and RS Williams (DIR). 2016. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res 44(8):3829-3844. [Abstract] 2016 Goal 1
Ribas V, BG Drew, Z Zhou, J Phun, NY Kalajian, T Soleymani, P Daraei, K Widjaja, J Wanagat, TQ de Aguiar Vallim, AH Fluitt, S Bensinger, T Le, C Radu, JP Whitelegge, SW Beaven, P Tontonoz, AJ Lusis, BW Parks, L Vergnes, K Reue, H Singh, JC Bopassa, L Toro, E Stefani, MJ Watt, S Schenk, T Akerstrom, M Kelly, BK Pedersen, SC Hewitt (DIR), KS Korach (DIR) and AL Hevener. 2016. Skeletal muscle action of estrogen receptor alpha is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci. Transl. Med. 8(334):334ra54. [Abstract] 2016 Goal 1
Huen K, Calafat AM, Bradman A, Yousefi P, Eskenazi B, Holland N. 2016. Maternal phthalate exposure during pregnancy is associated with DNA methylation of LINE-1 and Alu repetitive elements in Mexican-American children. Environ Res 148:55-62. [Abstract] 2016 Goal 1
Maertens A, Bouhifd M, Zhao L, Odwin-DaCosta S, Kleensang A, Yager JD, Hartung T. 2016. Metabolomic network analysis of estrogen-stimulated MCF-7 cells: a comparison of overrepresentation analysis, quantitative enrichment analysis and pathway analysis versus metabolite network analysis. Arch Toxicol. 91(1):217-230. [Abstract] 2016 Goal 1
Gassman NR (DIR), E Coskun, P Jaruga, M Dizdaroglu and SH Wilson (DIR). 2016. Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts. Environ Health Perspect 124(8):1241-1252. [Abstract] 2016 Goal 1
Ryan KR (DNTP), Sirenko O, Parham F (DNTP), Hsieh JH (DNTP), Cromwell EF, Tice RR (DNTP), Behl M (DNTP). 2016. Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity. Neurotoxicology 53:271-281. [Abstract] 2016 Goal 1
Ren NS (DIR), M Ji (DIR), EJ Tokar (NTP), EL Busch, X Xu (DIR), D Lewis (DIR), X Li, A Jin, Y Zhang, WK Wu, W Huang (DIR), L Li (DIR), DC Fargo (DIR), TO Keku, RS Sandler and X Li (DIR). 2017. Haploinsufficiency of SIRT1 Enhances Glutamin Metabolism and Promotes Cancer Development. Curr Biol 27(4):483-494. [Abstract] 2017 Goal 1
Zang Q, K Mansouri, AJ Williams, RS Judson, DG Allen, WM Casey (DNTP) and NC Kleinstreuer (DNTP). 2017. In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning. J. Chem. Inf. Model 57(1):36-49. [Abstract] 2017 Goal 1
Gao L, Mutlu E (DNTP), Collins LB, Walker NJ (DNTP), Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. 2017. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chem Res Toxicol 30(3):794-803. [Abstract] 2017 Goal 1
Shaw ND (DIR), H Brand, ZA Kupchinsky, H Bengani, L Plummer, TI Jones, S Erdin, KA Williamson, J Rainger, A Stortchevoi, K Samocha, BB Currall, DS Dunican, RL Collins, JR Willer, A Lek, M Lek, M Nassan, S Pereira, T Kammin, D Lucente, A Silva, CM Seabra, C Chiang, Y An, M Ansari, JK Rainger, S Joss, JC Smith, MF Lippincott, SS Singh, N Patel, JW Jing, JR Law, N Ferraro, A Verloes, A Rauch, K Steindl, M Zweier, I Scheer, D Sato, N Okamoto, C Jacobsen, J Tryggestad, S Chernausek, LA Schimmenti, B Brasseur, C Cesaretti, JE Garcia-Ortiz, TP Buitrago, OP Silva, JD Hoffman, W Muhlbauer, KW Ruprecht, BL Loeys, M Shino, AM Kaindl, CH Cho, CC Morton, RR Meehan, V van Heyningen, EC Liao, R Balasubramanian, JE Hall (DIR), SB Seminara, D Macarthur, SA Moore, KI Yoshiura, JF Gusella, JA Marsh, JM Graham, Jr., AE Lin, N Katsanis, PL Jones, WF Crowley, Jr., EE Davis, DR FitzPatrick and ME Talkowski. 2017. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat. Genet. 49(2):238-248. [Abstract] 2017 Goal 1
Caglayan M (DIR), JK Horton (DIR), DP Dai (DIR), DF Stefanick (DIR), SH Wilson (DIR). 2017. Oxidized nucleotide insertion by pol beta confounds ligation during base excision repair. Nature Communications 8:14045. [Abstract] 2017 Goal 1
Wallace BD (DIR), Z Berman, GA Mueller (DIR), Y Lin, T Chang (DIR), SN Andres (DIR), JL Wojtaszek (DIR), EF DeRose (DIR), CD Appel (DIR), RE London (DIR), S Yan and RS Williams (DIR). APE2 Zf-GRF facilitates 3’-5’ resection of DNA damage following oxidative stress. Proc Natl Acad Sci 114(2):304-309. [Abstract] 2017 Goal 1
Williams CJ (DIR), A Chu, WN Jefferson (DIR), D Casero, D Sudhakar, N Khurana, CP Hogue, C Aryasomayajula, P Patel, P Sullivan, E Padilla-Banks (DIR), S Mohandessi, C Janzen and M Wadehra. 2017. Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency. J Pathol 242(2):246-259. [Abstract] 2017 Goal 1
Seok SH, W Lee, L Jiang, K Molugu, A Zheng, Y Li, S Park, CA Bradfield and Y Xing. 2017. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci 114(21):5431-5436. [Abstract] 2017 Goal 1
Cisse YM, Russart KL, Nelson RJ. 2017. Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity. Sci Rep 7:45497. [Abstract] 2017 Goal 1
Xiao S, JR Coppeta, HB Rogers, BC Isenberg, J Zhu, SA Olalekan, KE McKinnon, D Dokic, AS Rashedi, DJ Haisenleder, SS Malpani, CA Arnold-Murray, KW Chen, MY Jiang, L Bai, CT Nguyen, JY Zhang, MM Laronda, TJ Hope, KP Maniar, ME Pavone, MJ Avram, EC Sefton, S Getsios, JE Burdette, JJ Kim, JT Borenstein and TK Woodruff. 2017. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nat Commun 8:14584. [Abstract] 2017 Goal 1
Laronda MM, Rutz AL, Xiao S, Whelan KA, Duncan FE, Roth EW, Woodruff TK, Shah RN. 2017. A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Nat Commun 8:15261. [Abstract] 2017 Goal 1
Ferrucio B, M Tiago, RD Fannin (DIR), L Liu (DIR), K Gerrish (DIR), SS Maria-Engler, RS Paules (NTP) and SB de Moraes Barros. 2016. Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes. Toxicol In Vitro 38:67-76. [Abstract] 2016 Goal 1
Stanko JP (NTP), GE Kissling (DIR), VA Chappell (NTP) and SE Fenton (NTP). 2016. Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies: Implications for Timing of Carcinogen Exposure. Toxicol. Pathol 44(7):1021-1033. [Abstract] 2016 Goal 1
Behl M (DNTP), JR Rice (DNTP), MV Smith, CA Co, MF Bridge, J-H Hsieh (DNTP), JH Freedman and WA Boyd (DNTP). 2016. Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans. Toxicol Sci 154(2):241-252. [Abstract] 2016 Goal 1
Strickland J, Zang Q, Kleinstreuer N (DNTP), Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W (DNTP). 2016. Integrated decision strategies for skin sensitization hazard. J Appl Toxicol 36(9):1150–1162. [Abstract] 2016 Goal 1
Kleinstreuer NC (DNTP), Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM (DNTP), Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. 2016. Development and Validation of a Computational Model for Androgen Receptor Activity. Chem Res Toxicol 30(4):946-964. [Abstract] 2016 Goal 1
Rubel CA, SP Wu (DIR), L Lin, T Wang (DIR), RB Lanz, X Li, R Kommagani, HL Franco, SA Camper, Q Tong, JW Jeong, JP Lydon and FJ DeMayo (DIR). 2016. A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function. Cell Reports 17(5):1414-1425. [Abstract] 2016 Goal 1
Zhang J (DIR), McCann KL (DIR), Qiu C (DIR), Gonzalez LE (DIR), Baserga SJ, Hall TM (DIR). 2016. Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. Nat Commun 7:13085. [Abstract] 2016 Goal 1
Zhang S, Zhou B (DIR), Wang L (DIR), Li P (DIR), Bennett BD (DIR), Snyder R (DIR), Garantziotis S (DIR), Fargo DC (DIR), Cox AD, Chen L, Hu G (DIR). 2016. INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer. Oncogene 36(10):1430-1439. [Abstract] 2016 Goal 1
Lai L (DIR), Azzam KM (DIR), Lin WC (DIR), Rai P (DIR), Lowe JM (DIR), Gabor KA (DIR), Madenspacher JH (DIR), Aloor JJ (DIR), Parks JS, Naar AM, Fessler MB (DIR). 2016. MicroRNA-33 regulates the innate immune response via ATP binding cassette transporter-mediated remodeling of membrane microdomains. J Biol Chem 291(37):19651−19660. [Abstract] 2016 Goal 1
Liu C (DIR), Rodriguez K (DIR), Yao HH (DIR). 2016. Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development 143(20):3700-3710. [Abstract] 2016 Goal 1
Reid NM, Proestou DA, Clark BW, Warren WC, Colbourne JK, Shaw JR, Karchner SI, Hahn ME, Nacci D, Oleksiak MF, Crawford DL, Whitehead A. 2016. The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. Science 354(6317):1305-1308. [Abstract] 2016 Goal 1
Dunaway K, Goorha S, Matelski L, Urraca N, Lein PJ, Korf I, Reiter LT, LaSalle JM. 2016. Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns. Stem Cells. 35(4):981-988. [Abstract] 2016 Goal 1
Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. 2016. Oxidative guanine base damage regulates human telomerase activity. Nat Struct Mol Biol 23(12):1092–1100. [Abstract] 2016 Goal 1
Ho SM, Rao RC, To S, Schoch E, Tarapore P. 2016. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer 24(2):83-96. [Abstract] 2016 Goal 1
Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. 2016. An inducible long noncoding RNA amplifies DNA damage signaling. Nat Genet 48(11):1370-1376. [Abstract] 2016 Goal 1
Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. 2016. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep 17(11):3035-3048. [Abstract] 2016 Goal 1
Hewitt Fenton SE (NTP) and LS Birnbaum (OD). 2015. Timing of Environmental Exposures as a Critical Element in Breast Cancer Risk. J Clin Endocrinol Metab 100(9):3245-3250. [Abstract] 2015 Goal 2
Yeramaneni S, Dietrich KN, Yolton K, Parsons PJ, Aldous KM, Haynes EN. 2015. Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children. J Pediatr 167(2):253-9.e1. [Abstract] 2015 Goal 2
Salo PM (DIR), SJ Arbes, Jr., R Jaramillo, A Calatroni, CH Weir, ML Sever, JA Hoppin (DIR), KM Rose, AH Liu, PJ Gergen, HE Mitchell and DC Zeldin (DIR). 2014. Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol 134(2):350-359. [Abstract] 2014 Goal 2
Chen A, Yolton K, Rauch SA, Webster GM, Hornung R, Sjödin A, Dietrich KN, Lanphear BP. 2014. Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children through 5 Years of Age: The HOME Study. Environ Health Perspect 122(8):856-62. [Abstract] 2014 Goal 2
Davis DA, Bortolato M, Godar SC, Sander TK, Iwata N, Pakbin P, Shih JC, Berhane K, McConnell R, Sioutas C, Finch CE, Morgan TE. 2013. Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses.  PLoS One 8(5):e64128. [Abstract] 2014 Goal 2
Furlong MA, Engel SM, Barr DB, Wolff MS. 2014. Prenatal exposure to organophosphate pesticides and reciprocal social behavior in childhood. Environ Int 70:125-31. [Abstract] 2014 Goal 2
Perera FP, Wang S, Rauh V, Zhou H, Stigter L, Camann D, Jedrychowski W, Mroz E, Majewska R. 2013. Prenatal exposure to air pollution, maternal psychological distress, and child behavior. Pediatrics 132(5):e1284-94. [Abstract] 2014 Goal 2
Shelton JF, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz B, Hansen RL, Hertz-Picciotto I. 2014. Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study. Environ Health Perspect 122(10):1103-9. [Abstract] 2014 Goal 2
Chrysovergis K (DIR), X Wang (DIR), J Kosak (DIR), SH Lee, J Sik Kim (DIR), JF Foley (NTP), G Travlos (NTP), S Singh (DIR), S Joon Baek and TE Eling(DIR). 2014. NAG-1/GDF15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes (Lond) 38:1555-1564.
[Abstract]
2014 Goal 2
Stapleton PA, Minarchick VC, Yi J, Engels K, McBride CR, Nurkiewicz TR. 2013. Maternal engineered nanomaterial exposure and fetal microvascular function: does the Barker hypothesis apply? Am J Obstet Gynecol 209(3):227.e1-11. [Abstract] 2014 Goal 2
Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, Cecil KM, Dietrich KN, Puga A, Jirtle RL, Hoyo C. 2015. Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environ Health Perspect 124(5):666-73. [Abstract] 2015 Goal 2
Markunas CA (DIR), Xu Z (DIR), Harlid S (DIR), Wade PA (DIR), Lie RT, Taylor JA (DIR), Wilcox AJ (DIR). 2014. Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy. Environ Health Perspect 122(10):1147-1153. [Abstract] 2014 Goal 2
House, JS (DIR), Li, H (DIR), DeGraff, LM (DIR), Flake, G (NTP), Zeldin, DC (DIR) and London, SJ (DIR). 2014. Genetic variation in HTR4 and lung function: GWAS follow-up in mouse. FASEB J 29(1):323-335. [Abstract] 2015 Goal 2
Richardson JR, Roy A, Shalat SL, von Stein RT, Hossain MM, Buckley B, Gearing M, Levey AI, German DC. 2014. Elevated serum pesticide levels and risk for Alzheimer disease. JAMA Neurol 71(3):284-90. [Abstract] 2014 Goal 2
Stansfield KH, Ruby KN, Soares BD, McGlothan JL, Liu X, Guilarte TR. 2015. Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. Transl Psychiatry 5:e522. [Abstract] 2015 Goal 2
Cantoral A, Téllez-Rojo MM, Ettinger AS, Hu H, Hernández-Ávila M, Peterson K. 2015. Early introduction and cumulative consumption of sugar-sweetened beverages during the pre-school period and risk of obesity at 8-14 years of age. Pediatr Obes 11(1):68-74. [Abstract] 2015 Goal 2
French, JE (NTP), Gatti, DM, Morgan, DL (NTP), Kissling, GE (DIR), Shockley, KR (DIR), Knudsen, GA (OD), Shepard, KG, Price, HC, King, D (NTP), Witt, KL (NTP), Pedersen, LC (DIR), Munger, SC, Svenson, KL and Churchill, GA. 2014. Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity. Environ Health Perspect 123:237-245. [Abstract] 2015 Goal 2
Tyler CR, Hafez AK, Solomon ER, Allan AM. 2015. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol 288(1):40-51. [Abstract] 2015 Goal 2
Debes F, Weihe P, Grandjean P. 2015. Cognitive deficits at age 22 years associated with prenatal exposure to methylmercury. Cortex 74:358-369. [Abstract] 2015 Goal 2
Ekenga CC (DIR), CG Parks (DIR), AA D'Aloisio (DIR), LA DeRoo (DIR) and DP Sandler (DIR). 2014. Breast Cancer Risk after Occupational Solvent Exposure: the Influence of Timing and Setting. Cancer Res 74(11):3076-3083. [Abstract] 2014 Goal 2
Liu J, Liu X, Wang W, McCauley L, Pinto-Martin J, Wang Y, Li L, Yan C, Rogan WJ (DIR). 2014. Blood lead concentrations and children's behavioral and emotional problems: A Cohort Study. JAMA Pediatr 168(8):737-45. [Abstract] 2014 Goal 2
Weinberg, CR, Shi, M, Deroo, LA, Taylor, JA, Sandler, DP and Umbach, DM. 2014. Asymmetry in family history implicates nonstandard genetic mechanisms: application to the genetics of breast cancer. PLoS Genet 10(3):e1004174. [Abstract] 2014 Goal 2
Cho, HY (DIR), Jedlicka, AE, Gladwell, W (DIR), Marzec, J (DIR), McCaw, ZR (DIR), Bienstock, R (DIR) and Kleeberger, SR (DIR). 2014. Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice. Antioxid Redox Signal 22(4):325-338. [Abstract] 2015 Goal 2
Skinner MK, Manikkam M, Tracey R, Guerrero-Bosagna C, Haque M, Nilsson EE. 2013. Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity. BMC Med 11:228. [Abstract] 2014 Goal 2
Young, MT, Sandler, DP (DIR), DeRoo, LA (DIR), Vedal, S, Kaufman, JD and London, SJ (DIR). 2014. Ambient Air Pollution Exposure and Incident Adult Asthma in a Nationwide Cohort of U.S. Women. Am J Respir Crit Care Med 190(8):914-921. [Abstract] 2015 Goal 2
Teitelbaum SL, Belpoggi F, Reinlib L. 2015. Advancing research on endocrine disrupting chemicals in breast cancer: expert panel recommendations. Reprod Toxicol 54:141-147. [Abstract] 2015 Goal 2
Ciencewicki, JM (DIR), Wang, X (DIR), Marzec, J (DIR), Serra, ME, Bell, DA (DIR), Polack, FP and Kleeberger, SR (DIR). 2014. A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection. FASEB J 28(4):1947-1956. [Abstract] 2014 Goal 2
Fannin RD (DIR), K Gerrish (DIR), SO Sieber (DIR), PR Bushel (DIR), PB Watkins and RS Paules (NTP). 2015. Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen. Clin Pharmacol Ther 99:432-441. [Abstract] 2015 Goal 2
White AJ, Nichols HB, Bradshaw PT, Sandler DP (DIR). 2015. Overall and central adiposity and breast cancer risk in the Sister Study. Cancer 121(20):3700-8. [Abstract] 2015 Goal 2
Upson K (DIR), Harmon QE (DIR), Baird DD (DIR). 2015. Soy-Based Infant Formula Feeding and Ultrasound-Detected Uterine Fibroids among Young African-American Women with No Prior Clinical Diagnosis of Fibroids. Environ Health Perspect 124(6):769-75. [Abstract] 2015 Goal 2
Sen A, Heredia N, Senut MC, Land S, Hollocher K, Lu X, Dereski MO, Ruden DM. 2015. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren. Sci Rep 5:14466. [Abstract] 2015 Goal 2
Harley KG, Engel SM, Vedar MG, Eskenazi B, Whyatt RM, Lanphear BP, Bradman A, Rauh VA, Yolton K, Hornung RW, Wetmur JG, Chen J, Holland NT, Barr DB, Perera FP, Wolff MS. 2015. Prenatal Exposure to Organophosphorous Pesticides and Fetal Growth: Pooled Results from Four Longitudinal Birth Cohort Studies. Environ Health Perspect 124(7):1084-1092. [Abstract] 2015 Goal 2
Buckley JP, Engel SM, Braun JM, Whyatt RM, Daniels JL, Mendez MA, Richardson DB, Xu Y, Calafat AM, Wolff MS, Lanphear BP, Herring AH, Rundle AG. 2016. Prenatal phthalate exposures and body mass index among 4 to 7 year old children: A pooled analysis. Epidemiology 27(3):449-58. [Abstract] 2016 Goal 2
Bell MR, Thompson LM, Rodriguez K, Gore AC. 2016. Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 1. Sexually dimorphic effects on social and anxiety-like behaviors. Horm Behav 78:168-77. [Abstract] 2016 Goal 2
Bell MR, Hart BG, Gore AC. 2016. Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 2. Sex-specific neuromolecular effects in the brain. Mol Cell Endocrinol 420:125-37. [Abstract] 2016 Goal 2
Markunas CA (DIR), AJ Wilcox (DIR), Z Xu (DIR), BR Joubert (DIR), S Harlid (DIR), V Panduri (DIR), SE Haberg, W Nystad, SJ London (DIR), DP Sandler (DIR), RT Lie, PA Wade (DIR) and JA Taylor (DIR). 2016. Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults. PLoS ONE 11(7):e0156361 [Abstract] 2016 Goal 2
Rowe C, Gunier R, Bradman A, Harley KG, Kogut K, Parra K, Eskenazi B. 2016. Residential proximity to organophosphate and carbamate pesticide use during pregnancy, poverty during childhood, and cognitive functioning in 10-year-old children. Environ Res 150:128-137.   [Abstract] 2016 Goal 2
McGuinn LA, Voss RW, Laurent CA, Greenspan LC, Kushi LH, Windham GC. 2016. Residential proximity to traffic and female pubertal development. Environ Int 94:635-641. [Abstract] 2016 Goal 2
Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, Dudley JT. 2016. Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks. Bioinformatics 32(12):i101-i110. [Abstract] 2016 Goal 2
Jusko TA, Oktapodas M, Palkovičová Murinová L, Babinská K, Babjaková J, Verner MA, DeWitt JC, Thevenet-Morrison K, Čonka K, Drobná B, Chovancová J, Thurston SW, Lawrence BP, Dozier AM, Järvinen KM, Patayová H, Trnovec T, Legler J, Hertz-Picciotto I, Lamoree MH. 2016. Dietary Determinants of Perfluorooctane Sulfonic (PFOS) and Perfluorooctanoic Acid (PFOA) Concentrations in Human Colostrum. Environ Sci Technol 50(13):7152-62. [Abstract] 2016 Goal 2
O'Brien KM (DIR), Shi M (DIR), Sandler DP (DIR), Taylor JA (DIR), Zaykin DV (DIR), Keller J, Wise AS (DIR), Weinberg CR (DIR). 2016. A family-based, genome-wide association study of young-onset breast cancer: inherited variants and maternally mediated effects. Eur J Hum Genet 24(9):1316-23. [Abstract] 2016 Goal 2
Parks CG (DIR), AA D'Aloisio (DIR) and DP Sandler (DIR). 2016. Early Life Factors Associated with Adult-Onset Systemic Lupus Erythematosus in Women. Front Immunol 7(103):1-7. [Abstract] 2016 Goal 2
Stingone JA, McVeigh KH, Claudio L. 2016. Association between prenatal exposure to ambient diesel particulate matter and perchloroethylene with children's 3rd grade standardized test scores. Environ Res 148:144-153. [Abstract] 2016 Goal 2
Huen K, Calafat AM, Bradman A, Yousefi P, Eskenazi B, Holland N. 2016. Maternal phthalate exposure during pregnancy is associated with DNA methylation of LINE-1 and Alu repetitive elements in Mexican-American children. Environ Res 148:55-62. [Abstract] 2016 Goal 2
Mora-Zamorano FX, Klingler R, Murphy C, Basu N, Head JH, Carvan Iii MJ. 2016. Parental whole life cycle exposure to dietary methylmercury in zebrafish (Danio rerio) affects the behavior of offspring. Environ Sci Technol 50(9):4808-16. [Abstract] 2016 Goal 2
James P, Hart JE, Banay RF, Laden F. 2016. Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women. Environ Health Perspect 124(9):1344-52. [Abstract] 2016 Goal 2
Williams CJ (DIR), A Chu, WN Jefferson (DIR), D Casero, D Sudhakar, N Khurana, CP Hogue, C Aryasomayajula, P Patel, P Sullivan, E Padilla-Banks (DIR), S Mohandessi, C Janzen and M Wadehra. 2017. Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency. J Pathol 242(2):246-259. [Abstract] 2017 Goal 2
Cisse YM, Russart KL, Nelson RJ. 2017. Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity. Sci Rep 7:45497. [Abstract] 2017 Goal 2
Stanko JP (NTP), GE Kissling (DIR), VA Chappell (NTP) and SE Fenton (NTP). 2016. Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies: Implications for Timing of Carcinogen Exposure. Toxicol Pathol 44(7):1021-33. [Abstract] 2017 Goal 2
Reid NM, Proestou DA, Clark BW, Warren WC, Colbourne JK, Shaw JR, Karchner SI, Hahn ME, Nacci D, Oleksiak MF, Crawford DL, Whitehead A. 2016. The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. Science 354(6317):1305-1308. [Abstract] 2017 Goal 2
Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. 2016. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep 17(11):3035-3048. [Abstract] 2016 Goal 2
Taylor KW (NTP), DD Baird (DIR), AH Herring, LS Engel, HB Nichols, DP Sandler (DIR) and MA Troester. 2017. Associations among personal care product use patterns and exogenous hormone use in the NIEHS Sister Study. J Expo Sci Environ Epidemiol 27:458-464. [Abstract] 2017 Goal 2
Grau-Perez M, Kuo CC, Spratlen M, Thayer KA (NTP), Mendez MA, Hamman RF, Dabelea D, Adgate JL, Knowler WC, Bell RA, Miller FW (DIR), Liese AD, Zhang C, Douillet C, Drobna Z, Mayer-Davis EJ, Styblo M, Navas-Acien A. 2017. The Association of Arsenic Exposure and Metabolism with Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diabetes Care 40(1):46-53. [Abstract] 2017 Goal 2
Bernardi LA, Carnethon MR, de Chavez PJ, Ikhena DE, Neff LM, Baird DD (DIR), Marsh EE. 2017. Relationship between obesity and anti-Mullerian hormone in reproductive-aged African American women. Obesity (Silver Spring) 25(1):229-235. [Abstract] 2017 Goal 2
Zuccolo L, DeRoo LA, Wills AK, Davey Smith G, Suren P, Roth C, Stoltenberg C, Magnus P. 2016. Pre-conception and prenatal alcohol exposure from mothers and fathers drinking and head circumference: results from the Norwegian Mother-Child Study (MoBa). Sci Rep 7:39535. [Abstract] 2017 Goal 2
Renzetti S, Just AC, Burris HH, Oken E, Amarasiriwardena C, Svensson K, Mercado-Garcia A, Cantoral A, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM. 2017. The association of lead exposure during pregnancy and childhood anthropometry in the Mexican PROGRESS cohort. Environ Res 152:226-232. [Abstract] 2017 Goal 2
Eckel SP, Cockburn M, Shu YH, Deng H, Lurmann FW, Liu L, Gilliland FD. 2016. Air pollution affects lung cancer survival. Thorax 71(10):891-898. [Abstract] 2016 Goal 2
Zota AR, Linderholm L, Park JS, Petreas M, Guo T, Privalsky ML, Zoeller RT, Woodruff TJ. 2013. Temporal comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the serum of second trimester pregnant women recruited from San Francisco General Hospital, California. Environ Sci Technol 47(20):11776-84. [Abstract] 2014 Goal 3
Salo PM (DIR), SJ Arbes, Jr., R Jaramillo, A Calatroni, CH Weir, ML Sever, JA Hoppin (DIR), KM Rose, AH Liu, PJ Gergen, HE Mitchell and DC Zeldin (DIR). 2014. Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol 134(2):350-359. [Abstract] 2014 Goal 3
Davis DA, Bortolato M, Godar SC, Sander TK, Iwata N, Pakbin P, Shih JC, Berhane K, McConnell R, Sioutas C, Finch CE, Morgan TE. 2013. Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses. PLoS One 8(5):e64128. [Abstract] 2014 Goal 3
Perera FP, Wang S, Rauh V, Zhou H, Stigter L, Camann D, Jedrychowski W, Mroz E, Majewska R. 2013. Prenatal exposure to air pollution, maternal psychological distress, and child behavior. Pediatrics 132(5):e1284-94. [Abstract] 2014 Goal 3
Rojas D, Rager JE, Smeester L, Bailey KA, Drobná Z, Rubio-Andrade M, Stýblo M, García-Vargas G, Fry RC. 2015. Prenatal Arsenic Exposure and the Epigenome: Identifying Sites of 5-methylcytosine Alterations that Predict Functional Changes in Gene Expression in Newborn Cord Blood and Subsequent Birth Outcomes. Toxicol Sci 143(1):97-106. [Abstract] 2015 Goal 3
Whitworth KW, RM Bornman, JI Archer, MO Kudumu, GS Travlos (NTP), RE Wilson (NTP) and MP Longnecker (DIR). 2014. Predictors of Plasma DDT and DDE Concentrations among Women Exposed to Indoor Residual Spraying for Malaria Control in the South African Study of Women and Babies (SOWB). Environ. Health Perspect 122(6):545-552. [Abstract] 2014 Goal 3
Patel CJ, Ioannidis JP. 2014. Placing epidemiological results in the context of multiplicity and typical correlations of exposures. J Epidemiol Community Health 68(11):1096-100. [Abstract] 2014 Goal 3
Thayer KA (NTP), DR Doerge, D Hunt (DIR), SH Schurman (DIR), NC Twaddle, MI Churchwell, S Garantziotis (DIR), GE Kissling (DIR), MR Easterling, JR Bucher (NTP) and LS Birnbaum (OD). 2015. Pharmacokinetics of bisphenol A in humans following a single oral administration. Environ Int 83:107-115. [Abstract] 2015 Goal 3
Lebov JF, LS Engel, D Richardson, SL Hogan, JA Hoppin and DP Sandler (DIR). 2015. Pesticide use and risk of end-stage renal disease among licensed pesticide applicators in the Agricultural Health Study. Occup Environ Med 73(1):3-12. [Abstract] 2015 Goal 3
Ji JS, Schwartz J, Sparrow D, Hu H, Weisskopf MG. 2014. Occupational Determinants of Cumulative Lead Exposure: Analysis of Bone Lead Among Men in the VA Normative Aging Study. J Occup Environ Med 56(4):435-40. [Abstract] 2014 Goal 3
Stapleton PA, Minarchick VC, Yi J, Engels K, McBride CR, Nurkiewicz TR. 2013. Maternal engineered nanomaterial exposure and fetal microvascular function: does the Barker hypothesis apply? Am J Obstet Gynecol 209(3):227.e1-11. [Abstract] 2014 Goal 3
Verner MA, Gaspar FW, Chevrier J, Gunier RB, Sjödin A, Bradman A, Eskenazi B. 2015. Increasing sample size in prospective birth cohorts: back-extrapolating prenatal levels of persistent organic pollutants in newly enrolled children. Environ Sci Technol 49(6):3940-8. [Abstract] 2015 Goal 3
House, JS (DIR), Li, H (DIR), DeGraff, LM (DIR), Flake, G (NTP), Zeldin, DC (DIR) and London, SJ (DIR). 2014. Genetic variation in HTR4 and lung function: GWAS follow-up in mouse. FASEB J 29(1):323-335. [Abstract] 2015 Goal 3
Harvey JB (DNTP), Hong HH (DNTP), Bhusari S, Ton TV (DNTP), Wang Y (DNTP), Foley JF (DNTP), Peddada SD (DIR), Hooth M (DNTP), DeVito M (DNTP), Nyska A, Pandiri AR (DNTP), Hoenerhoff MJ (DNTP). 2015. F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation. Veterinary pathology 53(1):170-181. [Abstract] 2015 Goal 3
Richardson JR, Roy A, Shalat SL, von Stein RT, Hossain MM, Buckley B, Gearing M, Levey AI, German DC. 2014. Elevated serum pesticide levels and risk for Alzheimer disease. JAMA Neurol 71(3):284-90. [Abstract] 2014 Goal 3
French, JE (NTP), Gatti, DM, Morgan, DL (NTP), Kissling, GE (DIR), Shockley, KR (DIR), Knudsen, GA (OD), Shepard, KG, Price, HC, King, D (NTP), Witt, KL (NTP), Pedersen, LC (DIR), Munger, SC, Svenson, KL and Churchill, GA. 2014. Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity. Environ. Health Perspect 123:237-245. [Abstract] 2015 Goal 3
Hewitt SC (DIR), W Winuthayanon (DIR), B Pockette (DIR), RT Kerns (DIR), JF Foley (NTP), N Flagler (NTP), E Ney (NTP), A Suksamrarn, P Piyachaturawat, PR Bushel (DIR) and KS Korach(DIR). 2015. Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice. Nat. Biotechnol. Environ. Health Perspect 123(4):344-352. [Abstract] 2015 Goal 3
Person RJ (DNTP), Olive Ngalame NN (DNTP), Makia NL (DIR), Bell MW (DNTP), Waalkes MP (DNTP), Tokar EJ (DNTP). 2015. Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells. Toxicology and applied pharmacology 286(1):36-43. [Abstract] 2015 Goal 3
Prins GS, Hu WY, Shi GB, Hu DP, Majumdar S, Li G, Huang K, Nelles JL, Ho SM, Walker CL, Kajdacsy-Balla A, van Breemen RB. 2014. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology 155(3):805-17. [Abstract] 2014 Goal 3
Vaughan JM, Garrett BJ, Prophete C, Horton L, Sisco M, Soukup JM, Zelikoff JT, Ghio A, Peltier RE, Asgharian B, Chen LC, Cohen MD. 2014. A novel system to generate WTC dust particles for inhalation exposures. Journal of Exposure Science and Environmental Epidemiology 24(1):105-112. [Abstract] 2014 Goal 3
Harley KG, Engel SM, Vedar MG, Eskenazi B, Whyatt RM, Lanphear BP, Bradman A, Rauh VA, Yolton K, Hornung RW, Wetmur JG, Chen J, Holland NT, Barr DB, Perera FP, Wolff MS. 2015. Prenatal Exposure to Organophosphorous Pesticides and Fetal Growth: Pooled Results from Four Longitudinal Birth Cohort Studies. Environ Health Perspect 124(7):1084-92. [Abstract] 2015 Goal 3
Sen A, Heredia N, Senut MC, Land S, Hollocher K, Lu X, Dereski MO, Ruden DM. 2015. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren. Sci Rep 5:14466. [Abstract] 2015 Goal 3
Buckley JP, Engel SM, Braun JM, Whyatt RM, Daniels JL, Mendez MA, Richardson DB, Xu Y, Calafat AM, Wolff MS, Lanphear BP, Herring AH, Rundle AG. 2016. Prenatal phthalate exposures and body mass index among 4 to 7 year old children: A pooled analysis. Epidemiology 27(3):449-58. [Abstract] 2016 Goal 3
Mendelsohn E, Hagopian A, Hoffman K, Butt CM, Lorenzo A, Congleton J, Webster TF, Stapleton HM. 2016. Nail polish as a source of exposure to triphenyl phosphate. Environ Int 86:45-51. [Abstract] 2016 Goal 3
Reese SE (DIR), S Zhao (DIR), MC Wu, BR Joubert (DERT), CL Parr (DIR), SE Haberg, PM Ueland, RM Nilsen, O Midttun, SE Vollset, SD Peddada (DIR), W Nystad and SJ London (DIR). 2016. DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy. Environ Health Perspect 125:760-766. [Abstract] 2016 Goal 3
Bonner MR, LE Beane Freeman, JA Hoppin, S Koutros, DP Sandler (DIR), CF Lynch, CJ Hines, K Thomas, A Blair and MC Alavanja. 2016. Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study. Environ Health Perspect 125(4):544-551. [Abstract] 2016 Goal 3
Parks CG (DIR), JA Hoppin, AJ DeRoos, KH Costenbader, MC Alavanja and DP Sandler (DIR). 2016. Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures. Environ Health Perspect 124(11):1728-1734. [Abstract] 2016 Goal 3
Rowe C, Gunier R, Bradman A, Harley KG, Kogut K, Parra K, Eskenazi B. 2016. Residential proximity to organophosphate and carbamate pesticide use during pregnancy, poverty during childhood, and cognitive functioning in 10-year-old children. Environ Res 150:128-137. [Abstract] 2016 Goal 3
McGuinn LA, Voss RW, Laurent CA, Greenspan LC, Kushi LH, Windham GC. 2016. Residential proximity to traffic and female pubertal development. Environ Int 94:635-641. [Abstract] 2016 Goal 3
Paquette AG, Houseman EA, Green BB, Lesseur C, Armstrong DA, Lester B, Marsit CJ. 2016. Regions of variable DNA methylation in human placenta associated with newborn neurobehavior. Epigenetics 11(8):603-13. [Abstract] 2016 Goal 3
Hu XC, Andrews DQ, Lindstrom AB, Bruton TA,  Schaider LA, Grandjean P, Lohmann R, Carignan CC, Blum A, Balan SA, Higgins CP, Sunderland EM. 2016. Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Drinking Water Linked to Industrial Sites, Military Fire Training Areas, and Wastewater Treatment Plants. Environ Sci Technol Lett 3(10):344-350. [Abstract] 2016 Goal 3
Mora-Zamorano FX, Klingler R, Murphy C, Basu N, Head JH, Carvan III J. 2016. Parental whole life cycle exposure to dietary methylmercury in zebrafish (Danio rerio) affects the behavior of offspring. Environ Sci Technol 50(9):4808-16. [Abstract] 2016 Goal 3
Xiao S, JR Coppeta, HB Rogers, BC Isenberg, J Zhu, SA Olalekan, KE McKinnon, D Dokic, AS Rashedi, DJ Haisenleder, SS Malpani, CA Arnold-Murray, KW Chen, MY Jiang, L Bai, CT Nguyen, JY Zhang, MM Laronda, TJ Hope, KP Maniar, ME Pavone, MJ Avram, EC Sefton, S Getsios, JE Burdette, JJ Kim, JT Borenstein and TK Woodruff. 2017. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nature Communications 8:14584. [Abstract] 2017 Goal 3
Dunaway K, Goorha S, Matelski L, Urraca N, Lein PJ, Korf I, Reiter LT, LaSalle JM. 2016. Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns. Stem Cells 35(4):981-988. [Abstract] 2016 Goal 3
Ho SM, Rao RC, To S, Schoch E, Tarapore P. 2016. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer 24(2):83-96. [Abstract] 2016 Goal 3
O' Lenick CR, Chang HH, Kramer MR, Winquist A, Mulholland JA, Friberg MD, Sarnat SE. 2017. Ozone and childhood respiratory disease in three US cities: evaluation of effect measure modification by neighborhood socioeconomic status using a Bayesian hierarchical approach. Environ Health 16(1):36. [Abstract] 2017 Goal 3
Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. 2016. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep 17(11):3035-3048. [Abstract] 2016 Goal 3
Grau-Perez M, CC Kuo, M Spratlen, KA Thayer (NTP), MA Mendez, RF Hamman, D Dabelea, JL Adgate, WC Knowler, RA Bell, FW Miller (DIR), AD Liese, C Zhang, C Douillet, Z Drobna, EJ Mayer-Davis, M Styblo and A Navas-Acien. 2016. The Association of Arsenic Exposure and Metabolism with Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diabetes Care 40(1):46-53. [Abstract] 2017 Goal 3
Zuccolo L, DeRoo LA, Wills AK, Davey Smith G, Suren P, Roth C, Stoltenberg C, Magnus P. 2016. Pre-conception and prenatal alcohol exposure from mothers and fathers drinking and head circumference: results from the Norwegian Mother-Child Study (MoBa). Sci Rep 7:39535. [Abstract] 2017 Goal 3
Renzetti S, Just AC, Burris HH, Oken E, Amarasiriwardena C, Svensson K, Mercado-Garcia A, Cantoral A, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM. 2017. The association of lead exposure during pregnancy and childhood anthropometry in the Mexican PROGRESS cohort. Environ Res 152:226-232. [Abstract] 2016 Goal 3
Eckel SP, Cockburn M, Shu YH, Deng H, Lurmann FW, Liu L, Gilliland FD. 2016. Air pollution affects lung cancer survival. Thorax 71(10):891-898. [Abstract] 2016 Goal 3
Chen A, Yolton K, Rauch SA, Webster GM, Hornung R, Sjödin A, Dietrich KN, Lanphear BP. 2014. Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children through 5 Years of Age: The HOME Study. Environ Health Perspect 122(8):856-62. [Abstract] 2014 Goal 4
Furlong MA, Engel SM, Barr DB, Wolff MS. 2014. Prenatal exposure to organophosphate pesticides and reciprocal social behavior in childhood. Environ Int 70:125-31. [Abstract] 2015 Goal 4
Shelton JF, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz B, Hansen RL, Hertz-Picciotto I. 2014. Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study. Environ Health Perspect 122(10):1103-9. [Abstract] 2014 Goal 4
Chrysovergis K (DIR), X Wang (DIR), J Kosak (DIR), SH Lee, J Sik Kim (DIR), JF Foley (NTP), G Travlos (NTP), S Singh (DIR), S Joon Baek and TE Eling(DIR). 2014. NAG-1/GDF15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes (Lond) 38(12):1555-64. [Abstract] 2014 Goal 4
Hernández-Cadena L, Zeldin DC (DIR), Barraza-Villarreal A, Sever ML (DIR), Sly PD, London SJ (DIR), Escamilla-Nuñez MC, Romieu I. 2015. Indoor determinants of dustborne allergens in Mexican homes. Allergy Asthma Proc 36(2):130-7. [Abstract] 2015 Goal 4
Lu K, Mahbub R, Cable PH, Ru HY, Parry NMA, Bodnar WM, Wishnok JS, Styblo M, Swenberg JA, Fox JG and Tannenbaum SR. 2014. Gut Microbiome Phenotypes Driven by Host Genetics Affect Arsenic Metabolism. Chem. Res. Toxicol 27(2):172-174. [Abstract] 2014 Goal 4
Bobb JF, Valeri L, Claus Henn B, Christiani DC, Wright RO, Mazumdar M, Godleski JJ, Coull BA. 2015. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics 16(3):493-508. [Abstract] 2015 Goal 4
Goodson WH et al., 2015. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis 36(Suppl 1):S254-296. [Abstract] 2015 Goal 4
Whitworth KW, Baird DD (DIR), Steiner AZ, Bornman RM, Travlos GS (DIR), Wilson RE (DIR), Longnecker MP (DIR). 2015. Anti-müllerian hormone and lifestyle, reproductive, and environmental factors among women in rural South Africa. Epidemiology 26(3):429-35. [Abstract] 2015 Goal 4
Fang M, Webster TF, Stapleton HM. 2015. Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust. Environ Sci Technol 49(16):10057-64. [Abstract] 2015 Goal 4
Thorne PS, Mendy A, Metwali N, Salo P, Co C, Jaramillo R, Rose KM, Zeldin DC. 2015. Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the United States. J Respir Crit Care Med 192(11):1287-97. [Abstract] 2015 Goal 4
Allen JG, Flanigan SS, LeBlanc M, Vallarino J, MacNaughton P, Stewart JH, Christiani DC. 2015. Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes. Environ Health Perspect 124(6):733-9. [Abstract] 2015 Goal 4
Sen A, Heredia N, Senut MC, Land S, Hollocher K, Lu X, Dereski MO, Ruden DM. 2015. Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren. Sci Rep 5:14466. [Abstract] 2015 Goal 4
Davé V, Street K, Francis S, Bradman A, Riley L, Eskenazi B, Holland N. 2016. Bacterial microbiome of breast milk and child saliva from low-income Mexican-American women and children. Pediatr Res 79(6):846-54. [Abstract] 2016 Goal 4
Hicks KD, Sullivan AW, Cao J, Sluzas E, Rebuli M, Patisaul HB. 2016. Interaction of bisphenol A (BPA) and soy phytoestrogens on sexually dimorphic sociosexual behaviors in male and female rats. Horm Behav 84:121-126. [Abstract] 2016 Goal 4
Zota AR, Phillips CA, Mitro SD. 2016. Recent Fast Food Consumption and Bisphenol A and Phthalates Exposures among the U.S. Population in NHANES, 2003-2010. Environ Health Perspect 124(10):1521-1528. [Abstract] 2016 Goal 4
Gao L, Mutlu E (DNTP), Collins LB, Walker NJ (DNTP), Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. 2017. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chem Res Toxicol 30(3):794-803. [Abstract] 2017 Goal 4
Ferrucio B, M Tiago, RD Fannin (DIR), L Liu (DIR), K Gerrish (DIR), SS Maria-Engler, RS Paules (NTP) and SB de Moraes Barros. 2016. Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes. Toxicol In Vitro 38:67-76. [Abstract] 2016 Goal 4
Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. 2016. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. Cell Rep 17(11):3035-3048. [Abstract] 2016 Goal 4
O' Lenick CR, Chang HH, Kramer MR, Winquist A, Mulholland JA, Friberg MD, Sarnat SE. 2017. Ozone and childhood respiratory disease in three US cities: evaluation of effect measure modification by neighborhood socioeconomic status using a Bayesian hierarchical approach. Environ Health 16(1):36. [Abstract] 2017 Goal 4
Zhong J, Trevisi L, Urch B, Lin X, Speck M, Coull BA, Liss G, Thompson A, Wu S, Wilson A, Koutrakis P, Silverman F, Gold DR, Baccarelli AA. 2017. B-vitamin Supplementation Mitigates Effects of Fine Particles on Cardiac Autonomic Dysfunction and Inflammation: A Pilot Human Intervention Trial. Sci Rep 7:45322. [Abstract] 2017 Goal 4
Andreotti G, Freedman ND, Silverman DT, Lerro CC, Koutros S, Hartge P, Alavanja MC, Sandler DP (DIR), Beane Freeman L. 2016. Tobacco use and cancer risk in the Agricultural Health Study. Cancer Epidemiol Biomarkers Prev 26(5):769-778. [Abstract] 2016 Goal 4
Eckel SP, Cockburn M, Shu YH, Deng H, Lurmann FW, Liu L, Gilliland FD. 2016. Air pollution affects lung cancer survival. Thorax 71(10):891-898. [Abstract] 2016 Goal 4
Yueh M-F, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, and Tukey RH. 2014. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci U S A 111(48):17200-17205. [Abstract] 2015 Goal 5
Nazarenko Y, Lioy PJ, Mainelis G. 2014. Quantitative assessment of inhalation exposure and deposited dose of aerosol from nanotechnology-based consumer sprays. Environ Sci Nano 1(2):161-171. [Abstract] 2015 Goal 5
Davis DA, Bortolato M, Godar SC, Sander TK, Iwata N, Pakbin P, Shih JC, Berhane K, McConnell R, Sioutas C, Finch CE, Morgan TE. 2013. Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses. PLoS One 8(5):e64128. [Abstract] 2014 Goal 5
Perera FP, Wang S, Rauh V, Zhou H, Stigter L, Camann D, Jedrychowski W, Mroz E, Majewska R. 2013. Prenatal exposure to air pollution, maternal psychological distress, and child behavior. Pediatrics 32(5):e1284-94. [Abstract] 2014 Goal 5
Lowe SR, Kwok RK (DIR), Payne J, Engel LS (DIR), Galea S, Sandler DP (DIR). 2015. Mental health service use by cleanup workers in the aftermath of the Deepwater Horizon oil spill. Soc Sci Med 130:125-34. [Abstract] 2015 Goal 5
Waalkes MP (NTP), Qu W (NTP), Tokar EJ (NTP), Kissling GE (DIR), Dixon D (NTP). 2014. Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses. Arch Toxicol 88(8):1619-29. [Abstract] 2014 Goal 5
Paulik LB, Donald CE, Smith BW, Tidwell LG, Hobbie KA, Kincl L, Haynes EN, Anderson KA. 2015. Impact of Natural Gas Extraction on PAH Levels in Ambient Air. Environ Sci Technol 49(8):5203-10. [Abstract] 2014 Goal 5
Carignan CC, Cottingham KL, Jackson BP, Farzan SF, Gandolfi AJ, Punshon T, Folt CL, Karagas MR. 2015. Estimated exposure to arsenic in breastfed and formula-fed infants in a United States cohort. Environ Health Perspect 123(5):500-6. [Abstract] 2015 Goal 5
West JJ, Smith SJ, Silva RA, Naik V, Zhang YQ, Adelman Z, Fry MM, Anenberg S, Horowitz LW and Lamarque JF. 2013. Co-benefits of mitigating global greenhouse gas emissions for future air quality and human health. Nat Clim Chang 3(10):885-889. [Abstract] 2014 Goal 5
Liu J, Liu X, Wang W, McCauley L, Pinto-Martin J, Wang Y, Li L, Yan C, Rogan WJ (DIR). 2014. Blood lead concentrations and children's behavioral and emotional problems: A Cohort Study. JAMA Pediatr 168(8):737-45. [Abstract] 2014 Goal 5
Vaughan JM, Garrett BJ, Prophete C, Horton L, Sisco M, Soukup JM, Zelikoff JT, Ghio A, Peltier RE, Asgharian B, Chen LC, Cohen MD. 2014. A novel system to generate WTC dust particles for inhalation exposures. Journal of Exposure Science and Environmental Epidemiology 24(1):105-112. [Abstract] 2014 Goal 5
Gerona RR, Pan J, Zota AR, Schwartz JM, Friesen M, Taylor JA, Hunt PA, Woodruff TJ. 2016. Direct measurement of Bisphenol A (BPA), BPA glucuronide and BPA sulfate in a diverse and low-income population of pregnant women reveals high exposure, with potential implications for previous exposure estimates: a cross-sectional study. Environ Health 15(1):50. [Abstract] 2016 Goal 5
Ferrucio B, M Tiago, RD Fannin (DIR), L Liu (DIR), K Gerrish (DIR), SS Maria-Engler, RS Paules (NTP) and SB de Moraes Barros. 2016. Molecular effects of 1-naphthyl-methylcarbamate and solar radiation exposures on human melanocytes. Toxicol In Vitro 38:67-76. [Abstract] 2016 Goal 5
Stueckle TA, DC Davidson, R Derk, TG Kornberg, D Schwegler-Berry, SV Pirela, G Deloid, P Demokritou, S Luanpitpong, Y Rojanasakul and L Wang. 2017. Evaluation of tumorigenic potential of CeO2 and Fe2O3 engineered nanoparticles by a human cell in vitro screening model. NanoImpact 6:39-54. [Abstract] 2017 Goal 5
Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-Lozano R, Macín-Pérez G, Granados-Arriola J, Huntsman S, Galanter JM, Via M, Ford JG, Chapela R, Rodriguez-Cintron W, Rodríguez-Santana JR, Romieu I, Sienra-Monge JJ, del Rio Navarro B, London SJ (DIR), Ruiz-Linares A, Garcia-Herrera R, Estrada K, Hidalgo-Miranda A, Jimenez-Sanchez G, Carnevale A, Soberón X, Canizales-Quinteros S, Rangel-Villalobos H, Silva-Zolezzi I, Burchard EG, Bustamante CD. 2014. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science 344(6189):1280-5. [Abstract] 2014 Goal 6
Yeramaneni S, Dietrich KN, Yolton K, Parsons PJ, Aldous KM, Haynes EN. 2015. Secondhand Tobacco Smoke Exposure and Neuromotor Function in Rural Children. J Pediatr 167(2):253-9. [Abstract] 2015 Goal 6
Nichols HB, LA DeRoo, DR Scharf and DP Sandler (DIR). Risk-benefit profiles of women using tamoxifen for chemoprevention. Journal of the National Cancer Institute 107(1):1-8. [Abstract] 2015 Goal 6
Furlong MA, Engel SM, Barr DB, Wolff MS. 2014. Prenatal exposure to organophosphate pesticides and reciprocal social behavior in childhood. Environ Int 70:125-31. [Abstract] 2014 Goal 6
Whitworth KW, RM Bornman, JI Archer, MO Kudumu, GS Travlos (NTP), RE Wilson (NTP) and MP Longnecker (DIR). 2014. Predictors of Plasma DDT and DDE Concentrations among Women Exposed to Indoor Residual Spraying for Malaria Control in the South African Study of Women and Babies (SOWB). Environ Health Perspect 122:545-552. [Abstract] 2014 Goal 6
Lebov JF, LS Engel, D Richardson, SL Hogan, JA Hoppin and DP Sandler (DIR). 2015. Pesticide use and risk of end-stage renal disease among licensed pesticide applicators in the Agricultural Health Study. Occup Environ Med 73(1):3-12. [Abstract] 2015 Goal 6
Medehouenou TC, Ayotte P, St-Jean A, Meziou S, Roy C, Muckle G, Lucas M. 2015. Overweight and Obesity Prevalence Among School-Aged Nunavik Inuit Children According to Three Body Mass Index Classification Systems. J Adolesc Health 57(1):31-6. [Abstract] 2015 Goal 6
Ji JS, Schwartz J, Sparrow D, Hu H, Weisskopf MG. 2014. Occupational Determinants of Cumulative Lead Exposure: Analysis of Bone Lead Among Men in the VA Normative Aging Study. J Occup Environ Med 56(4):435-40. [Abstract] 2014 Goal 6
Shelton JF, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz B, Hansen RL, Hertz-Picciotto I. Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study. Environ Health Perspect 122(10):1103-9. [Abstract] 2014 Goal 6
Proper SP, Saini Y, Greenwood KK, Bramble LA, Downing NJ, Harkema JR, LaPres JJ. 2014. Loss of Hypoxia-Inducible Factor 2 Alpha in the Lung Alveolar Epithelium of Mice Leads to Enhanced Eosinophilic Inflammation in Cobalt-Induced Lung Injury. Toxicol Sci 137(2):447-457. [Abstract] 2014 Goal 6
Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, Cecil KM, Dietrich KN, Puga A, Jirtle RL, Hoyo C. 2015. Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environ Health Perspect 124(5):666-73. [Abstract] 2015 Goal 6
Hernández-Valero MA, Rother J, Gorlov I, Frazier M, Gorlova O. 2013. Interplay between polymorphisms and methylation in the H19/IGF2 gene region may contribute to obesity in Mexican-American children. J Dev Orig Health Dis 4(6):499-506. [Abstract] 2014 Goal 6
Ojo KD, Soneja SI, Scrafford CG, Khatry SK, LeClerq SC, Checkley W, Katz J, Breysse PN, Tielsch JM. 2015. Indoor Particulate Matter Concentration, Water Boiling Time, and Fuel Use of Selected Alternative Cookstoves in a Home-Like Setting in Rural Nepal. Int J Environ Res Public Health 12(7):7558-81. [Abstract] 2015 Goal 6
Ware DN, Lewis J, Hopkins S, Boyer B, Montrose L, Noonan CW, Semmens EO, Ward TJ. 2014. Household reporting of childhood respiratory health and air pollution in rural Alaska Native communities. Int J Circumpolar Health 73:1-10. [Abstract] 2014 Goal 6
Xu Z, Taylor JA. 2014. Genome-wide age-related DNA methylation changes in blood and other tissues relate to histone modification, expression and cancer. Carcinogenesis 35(2):356-364. [Abstract] 2014 Goal 6
Myers SL (DIR), Yang CZ, Bittner GD, Witt KL (NTP), Tice RR (NTP), Baird DD (DIR). 2014. Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products. J Expo Sci Environ Epidemiol 25:271-277. [Abstract] 2014 Goal 6
Weinberg CR, Shi M, Deroo LA, Taylor JA, Sandler DP and Umbach DM. 2014. Asymmetry in family history implicates nonstandard genetic mechanisms: application to the genetics of breast cancer. PLoS Genet 10(3):e1004174. [Abstract] 2014 Goal 6
Jukic AM (DIR), Steiner AZ and Baird DD (DIR). 2015. Association between serum 25-hydroxyvitamin D and ovarian reserve in premenopausal women. Menopause 22(3):312-6. [Abstract] 2014 Goal 6
Young MT, Sandler DP (DIR), DeRoo LA (DIR), Vedal S, Kaufman JD and London SJ (DIR). 2014. Ambient Air Pollution Exposure and Incident Adult Asthma in a Nationwide Cohort of U.S. Women Am J Respir Crit Care Med 190(8):914-921. [Abstract] 2015 Goal 6
Bensen JT, Xu ZL, McKeigue PM, Smith GJ, Fontham ETH, Mohler JL, Taylor JA. 2014. Admixture Mapping of Prostate Cancer in African Americans Participating in the North Carolina-Louisiana Prostate Cancer Project (PCaP). Prostate 74(1):1-9. [Abstract] 2014 Goal 6
Fabian MP, Adamkiewicz G, Stout NK, Sandel M, Levy JI. 2013. A simulation model of building intervention impacts on indoor environmental quality, pediatric asthma, and costs. J Allergy Clin Immunol 133(1):77-84. [Abstract] 2014 Goal 6
Harley KG, Engel SM, Vedar MG, Eskenazi B, Whyatt RM, Lanphear BP, Bradman A, Rauh VA, Yolton K, Hornung RW, Wetmur JG, Chen J, Holland NT, Barr DB, Perera FP, Wolff MS. 2015. Prenatal Exposure to Organophosphorous Pesticides and Fetal Growth: Pooled Results from Four Longitudinal Birth Cohort Studies.  Environ Health Perspect 124(7):1084-92. [Abstract] 2015 Goal 6
O' Lenick CR, Chang HH, Kramer MR, Winquist A, Mulholland JA, Friberg MD, Sarnat SE. 2017. Ozone and childhood respiratory disease in three US cities: evaluation of effect measure modification by neighborhood socioeconomic status using a Bayesian hierarchical approach. Environ Health 16(1):36. [Abstract] 2017 Goal 6
Bernardi LA, Carnethon MR, de Chavez PJ, Ikhena DE, Neff LM, Baird DD (DIR), Marsh EE. 2017. Relationship between obesity and anti-Mullerian hormone in reproductive-aged African American women. Obesity 25(1):229-235. [Abstract] 2017 Goal 6
Renzetti S, Just AC, Burris HH, Oken E, Amarasiriwardena C, Svensson K, Mercado-Garcia A, Cantoral A, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM. 2017. The association of lead exposure during pregnancy and childhood anthropometry in the Mexican PROGRESS cohort. 2017. Environ Res 152:226-232. [Abstract] 2017 Goal 6
Grau-Perez M, CC Kuo, M Spratlen, KA Thayer (NTP), MA Mendez, RF Hamman, D Dabelea, JL Adgate, WC Knowler, RA Bell, FW Miller (DIR), AD Liese, C Zhang, C Douillet, Z Drobna, EJ Mayer-Davis, M Styblo and A Navas-Acien. 2016. The Association of Arsenic Exposure and Metabolism with Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diabetes Care 40(1):46-53. [Abstract] 2016 Goal 6
Cesta MF (NTP), Malarkey DE (NTP), Herbert RA (NTP), Brix A, Hamlin MH, 2nd, Singletary E, Sills RC (NTP), Bucher JR (NTP) and Birnbaum LS (DIR). 2014. The National Toxicology Program Web-based Nonneoplastic Lesion Atlas: A Global Toxicology and Pathology Resource. Toxicol Pathol 42(2):458-60. [Abstract] 2014 Goal 7
Rooney AA (NTP), Boyles AL (NTP), Wolfe MS (NTP), Bucher JR (NTP), and Thayer KA (NTP). 2014. Systematic Review and Evidence Integration for Literature-Based Environmental Health Science Assessments. Environ Health Perspect 122(7):711-8. [Abstract] 2014 Goal 7
Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A. 2014. Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature 518(7539):355-359. [Abstract] 2015 Goal 7
Bobb JF, Valeri L, Claus Henn B, Christiani DC, Wright RO, Mazumdar M, Godleski JJ, Coull BA. 2014. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics 16(3):493-508. [Abstract] 2015 Goal 7
Hsieh JH (DNTP), Sedykh A, Huang R, Xia M, Tice RR (DNTP). 2015. A data analysis pipeline accounting for artifacts in tox21 quantitative high-throughput screening assays. J Biomol Screen 20(7):887-897. [Abstract] 2015 Goal 7
Vandenberg LN, M Agerstrand, A Beronius, C Beausoleil, A Bergman, LA Bero, CG Bornehag, CS Boyer, GS Cooper, I Cotgreave, D Gee, P Grandjean, KZ Guyton, U Hass, JJ Heindel (DERT), S Jobling, KA Kidd, A Kortenkamp, MR Macleod, OV Martin, U Norinder, M Scheringer, KA Thayer (NTP), J Toppari, P Whaley, TJ Woodruff and C Ruden. 2016. A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals. Environ Health Perspect 15(1):74. [Abstract] 2016 Goal 7
Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W (DNTP), Hinton D, Kanungo J, Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M (DNTP), Padilla S, Reif DM, Tanguay RL, Hamm J. 2016. Advancing toxicology research using in vivo high throughput toxicology with small fish models. ALTEX 33(4):435-452. [Abstract] 2016 Goal 7
Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert PF, Hecht SS, Bucher JR (DNTP), Stewart BW, Baan RA, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health Perspect 124(6):713-721 [Abstract] 2016 Goal 7
Strickland J, Zang Q, Kleinstreuer N (DNTP), Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W (DNTP). 2016. Integrated decision strategies for skin sensitization hazard. J Appl Toxicol 36(9):1150-1162. [Abstract] 2016 Goal 7
Kleinstreuer NC (DNTP), Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM (DNTP), Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. 2016. Development and Validation of a Computational Model for Androgen Receptor Activity. Chem Res Toxicol 30(4):946-964. [Abstract] 2016 Goal 7
Whitworth KW, RM Bornman, JI Archer, MO Kudumu, GS Travlos (NTP), RE Wilson (NTP) and MP Longnecker (DIR). 2014. Predictors of Plasma DDT and DDE Concentrations among Women Exposed to Indoor Residual Spraying for Malaria Control in the South African Study of Women and Babies (SOWB). Environ Health Perspect 122(6):545-552. [Abstract] 2014 Goal 8
Stotland NE, Sutton P, Trowbridge J, Atchley DS, Conry J, Trasande L, Gerbert B, Charlesworth A, Woodruff TJ. 2014. Counseling patients on preventing prenatal environmental exposures--a mixed-methods study of obstetricians. PLoS One 9(6):e98771. [Abstract] 2014 Goal 8
Chiarella SE, Soberanes S, Urich D, Morales-Nebreda L, Nigdelioglu R, Green D, Young JB, Gonzalez A, Rosario C, Misharin AV, Ghio AJ, Wunderink RG, Donnelly HK, Radigan KA, Perlman H, Chandel NS, Budinger GR, Mutlu GM. 2014. β₂-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. J Clin Invest 124(7):2935-46. [Abstract] 2015 Goal 9
Long Z, Jiang YM, Li XR, Fadel W, Xu J, Yeh CL, Long LL, Luo HL, Harezlak J, Murdoch JB, Zheng W, Dydak U. 2014. Vulnerability of welders to manganese exposure--a neuroimaging study. Neurotoxicology 45:285-92. [Abstract] 2015 Goal 9
Stapleton PA, McBride CR, Yi J, Nurkiewicz TR. 2015. Uterine microvascular sensitivity to nanomaterial inhalation: An in vivo assessment. Toxicol Appl Pharmacol 288(3):428-8. [Abstract] 2015 Goal 9
Just AC, Wright RO, Schwartz J, Coull BA, Baccarelli AA, Tellez-Rojo MM, Moody E, Wang Y, Lyapustin A, Kloog I. 2015. Using High-Resolution Satellite Aerosol Optical Depth To Estimate Daily PM2.5 Geographical Distribution in Mexico City. Environ Sci Technol 49(14):8576-84. [Abstract] 2015 Goal 9
Padula AM, Mortimer KM, Tager IB, Hammond SK, Lurmann FW, Yang W, Stevenson DK, Shaw GM. 2014. Traffic-related air pollution and risk of preterm birth in the San Joaquin Valley of California. Ann Epidemiol 24(12):888-95e4. [Abstract] 2014 Goal 9
Harper B, Sinche F, Wu RH, Gowrishankar M, Marquart G, Mackiewicz M, Harper SL. 2014. The Impact of Surface Ligands and Synthesis Method on the Toxicity of Glutathione-Coated Gold Nanoparticles. Nanomaterials (Basel) 4(2):355-371. [Abstract] 2014 Goal 9
Gao J, Tong L, Argos M, Scannell Bryan M, Ahmed A, Rakibuz-Zaman M, Kibriya MG, Jasmine F, Slavkovich V, Graziano JH, Ahsan H, Pierce BL. 2015. The Genetic Architecture of Arsenic Metabolism Efficiency: A SNP-Based Heritability Study of Bangladeshi Adults. Environ Health Perspect 123(10):985-92. [Abstract] 2015 Goal 9
Farzan SF, Chen Y, Rees JR, Zens MS, Karagas MR. 2015. Risk of death from cardiovascular disease associated with low-level arsenic exposure among long-term smokers in a US population-based study. Toxicol Appl Pharmacol 287(2):93-7. [Abstract] 2015 Goal 9
Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA. 2015. Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nat Commun 6:7834. [Abstract] 2015 Goal 9
Rojas D, Rager JE, Smeester L, Bailey KA, Drobná Z, Rubio-Andrade M, Stýblo M, García-Vargas G, Fry RC. 2015. Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes. Toxicol Sci 143(1):97-106. [Abstract] 2015 Goal 9
Young MJ (DIR), MM Humble (DIR), KL DeBalsi (DIR), KY Sun (DIR) and WC Copeland (DIR). 2015. POLG2 Disease Variants: Analyses Reveal a Dominant Negative Heterodimer, Altered Mitochondrial Localization, and Impaired Respiratory Capacity. Hum Mol Genet 24(18):5184-5197. [Abstract] 2015 Goal 9
Rooney JP, Ryde IT, Sanders LH, Howlett EH, Colton MD, Germ KE, Mayer GD, Greenamyre JT and Meyer JN. 2015. PCR based determination of mitochondrial DNA copy number in multiple species. Methods Mol Biol 1241:23-38 [Abstract] 2015 Goal 9
Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. 2014. Oncogenic KRAS confers chemoresistance by upregulating NRF2. Cancer Res 74(24):7430-41. [Abstract] 2015 Goal 9
Larson-Casey JL, Murthy S, Ryan AJ, Carter AB. 2014. Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. J Biol Chem 289(52):36204-19. [Abstract] 2015 Goal 9
Luz AL, Rooney JP, Kubik LL, Gonzalez CP, Song DH, Meyer JN. 2015. Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes. PLoS One 10(6):e0130940. [Abstract] 2015 Goal 9
Pellegrini KL, Han T, Bijol V, Saikumar J, Craciun FL, Chen WW, Fuscoe JC, Vaidya VS. 2014. MicroRNA-155 deficient mice experience heightened kidney toxicity when dosed with cisplatin. Toxicol Sci 141(2):484-92. [Abstract] 2014 Goal 9
Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. 2015. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke 46(5):1161-6. [Abstract] 2014 Goal 9
Hajat A, Allison M, Diez-Roux AV, Jenny NS, Jorgensen NW, Szpiro AA, Vedal S, Kaufman JD. 2015. Long-term exposure to air pollution and markers of inflammation, coagulation, and endothelial activation: a repeat-measures analysis in the Multi-Ethnic Study of Atherosclerosis (MESA). Epidemiology 26(3):310-20. [Abstract] 2015 Goal 9
Xiao J, Wang Q, Bircsak KM, Wen X, Aleksunes LM. 2015. In Vitro Screening of Environmental Chemicals Identifies Zearalenone as a Novel Substrate of the Placental BCRP/ABCG2 Transporter. Toxicol Res (Camb) 4(3):695-706. [Abstract] 2015 Goal 9
Faulkner RL, Wishard TJ, Thompson CK, Liu HH, Cline HT. 2015. FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles. Eneuro 2(1):e0055. [Abstract] 2015 Goal 9
Seo YA, Wessling-Resnick M. 2015. Ferroportin deficiency impairs manganese metabolism in flatiron mice. FASEB J 29(7):2726-33. [Abstract] 2015 Goal 9
Posnack NG, Idrees R, Ding H, Jaimes R 3rd, Stybayeva G, Karabekian Z, Laflamme MA, Sarvazyan N. 2015. Exposure to phthalates affects calcium handling and intercellular connectivity of human stem cell-derived cardiomyocytes. PLoS One 10(3):e0121927. [Abstract] 2015 Goal 9
Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. 2015. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci USA 112(29):9082-7. [Abstract] 2015 Goal 9
Patel CJ, Manrai AK. 2015. Development of exposome correlation globes to map out environment-wide associations. Pac Symp Biocomput 2015:231-42. [Abstract] 2015 Goal 9
Plavicki JS, Baker TR, Burns FR, Xiong KM, Gooding AJ, Hofsteen P, Peterson RE, Heideman W. 2014. Construction and characterization of a sox9b transgenic reporter line. Int J Dev Biol 58(9):693-9. [Abstract] 2014 Goal 9
Susiarjo M, Xin F, Bansal A, Stefaniak M, Li C, Simmons RA, Bartolomei MS. 2015. Bisphenol a exposure disrupts metabolic health across multiple generations in the mouse. Endocrinology 156(6):2049-58. [Abstract] 2015 Goal 9
Fang M, Webster TF, Stapleton HM. 2015. Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust. Environ Sci Technol 49(16):10057-64. [Abstract] 2015 Goal 9
Sjolund A, Nemec AA, Paquet N, Prakash A, Sung P, Doublié S, Sweasy JB. 2014. A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. PLoS Genet 10(11):e1004753. [Abstract] 2014 Goal 9
Schermerhorn KM, Delaney S. 2014. A chemical and kinetic perspective on base excision repair of DNA. Acc Chem Res 47(4):1238-46. [Abstract] 2014 Goal 9
Caglayan M (DIR), JK Horton (DIR), DP Dai (DIR), DF Stefanick (DIR) and SH Wilson (DIR). 2017. Oxidized nucleotide insertion by pol beta confounds ligation during base excision repair. Nature communications 8:14045. [Abstract] 2017 Goal 9
Cisse YM, Russart KL, Nelson RJ. 2017. Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity. Sci Rep 7:45497. [Abstract] 2017 Goal 9
Zhong J, Trevisi L, Urch B, Lin X, Speck M, Coull BA, Liss G, Thompson A, Wu S, Wilson A, Koutrakis P, Silverman F, Gold DR, Baccarelli AA. 2017. B-vitamin Supplementation Mitigates Effects of Fine Particles on Cardiac Autonomic Dysfunction and Inflammation: A Pilot Human Intervention Trial. Sci Rep 7:45322. [Abstract] 2017 Goal 9