Exposed! The Association of the Gut Microbiome with Dietary Exposures and Health Outcomes
The NIEHS Exposure Science and the Exposome Webinar Series
July 20, 2017
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Literature on Exposome
The NIEHS Strategic Plan places a significant emphasis on transforming exposure science through the development of new approaches to exposure assessment, the definition and dissemination of the exposome concept, and the development and demonstration of the exposome as a tool for both epidemiological and mechanistic research. In order to achieve this goal, NIEHS launched the Exposure Science and the Exposome Webinar Series on April 4, 2014 to foster discussions on international efforts in advancing exposure science and the exposome concept as well as challenges and opportunities in incorporating this concept in environmental health research.
Increasingly, the gut microbiome has been implicated in the etiology of cancer, not only as an infectious agent but also by modifying dietary exposures that influence disease risk. Unlike human metabolism, different groups of gut bacteria interact to alter exposures that influence disease risk. Though the composition and metabolism of the gut microbiome is influenced by diet, the gut microbiome can also modify dietary and other environmental exposures in ways that are detrimental or beneficial to the host. The purpose of this webinar is to introduce the role of the gut microbiome in human health, discuss common methodologic approaches to studying the gut microbiome, and focus on both infectious and metabolic microbiome pathways that may modify environmental exposures in humans.
Meredith A. J. Hullar, Ph.D., is a Principal Staff Scientist in the Public Health Sciences Division of the Fred Hutchinson Cancer Research Center. Her research focuses on the role of the microbiome in human health related to cancer. She has published numerous papers on how the microbiome alters dietary exposures. Her long-term research goal is to continue to explore and establish the multifaceted links between environmental exposures and the microbiome in relation to human health and disease. Dr. Hullar holds a Ph.D. from Harvard University and she completed her post-doctoral fellowship in Civil and Environmental Engineering at the University of Washington which both focused on understanding the role of the microbiome in complex systems.