DNA Repair Research Grantees
Susceptibility & Population Health Branch
| Name | Institution | Lead Scientist |
|---|---|---|
Role of DNA polymerase eta in errorfree bypass of DNA lesions & cancer prevention | Mount Sinai School of Medicine | Aneel Aggarwal |
Biological Effects of DNA Adducts Formed by Nitroaromatic Compounds | University of Connecticut Storrs | Ashis Basu; Zucai Suo |
Mechanisms of Environmental and Nuclear and Mitochondrial Mutagenesis | Fred Hutchinson Cancer Research Center | Jason Bielas |
Comparing and contrasting the biology of damage survival at a genomic level | University of Texas Health Science Center at San Antonio | Alexander Bishop |
Linkage of Lung Inflammation to 8-oxoguanine and OGG1 | University of Texas Medical Branch at Galveston | Istvan Boldogh |
High Throughput Technology for Assessing Global DSB Repair Capacity | Columbia University Health Sciences | David Brenner |
MMR-Coupled Translesion DNA Synthesis During Suppression of PAH-Induced Mutation | Oregon State University | Andrew Buermeyer; John Hays |
The Mechanism of Mitochondrial DNA Proofreading in Human Health and Disease | Medical University of South Carolina | Sherine Chan |
Regulation of the DNA damage Response | Stanford University | Karlene Cimprich |
Identifying Novel Mechanisms and Regulators of Genome Stability | Stanford University | Karlene Cimprich |
Cellular Responses to Environmental Insults and Risk for Melanoma Development | University of North Carolina Chapel Hill | Marila Cordeiro-Stone |
Molecular Mechanisms of Nitroarene Toxicity | State University New York Stony Brook | Carlos de los Santos |
DNA Oxidation Products and Endogenous DNA Adducts | Massachusetts Institute of Technology | Peter Dedon |
Inflammation as a Mediator of Dynamic DNA Mutations | Brown University | Sarah Delaney |
Cellular Responses to Oxidative Stress in Models of Colon Cancer Development | Emory University | Paul Doetsch |
Mouse Models of DNA Repair - Defective Human Diseases | University of Texas Southwestern Medical Center at Dallas | Errol Friedberg |
Hypoxia, Genetic Instability and DNA Mismatch Repair | Yale University | Peter Glazer |
SWI/SNF chromatin remodeling in nucleotide excision repair | University of Miami School of Medicine | Feng Gong |
Biochemical Basis of SOS-Induced Mutagenesis | University of Southern California | Myron Goodman |
Nucleoprotein structures formed at sites of DNA damage | University of North Carolina Chapel Hill | Jack Griffith |
Cellular Responses to Oxidative Stress in Models of Colon Cancer Development | State University New York Stony Brook | Arthur Grollman |
Molecular Biomarkers For Environmental Toxicants | Johns Hopkins University | John Groopman |
Polymerase Interactions with Carcinogen-modified DNA | Vanderbilt University | F. Guengerich |
Oxidative DNA damage processing; role in human pathology and aging | Stanford University | Philip Hanawalt |
Polymorphic variants of human DNA glycosylase NEIL2 and lung cancer susceptibility | University of Texas Medical Branch at Galveston | Tapas Hazra |
DNA Adducts of the Carcinogen Acetaldehyde | University of Minnesota Twin Cities | Stephen Hecht |
Humanized Mouse Models for the p53 R72P SNP | University of Texas MD Anderson Cancer Center | David Johnson |
Modification of DNA Polymerase Delta by a Novel Mechanism During Replication Stre | New York Medical College | Marietta Lee |
Arsenic-enhanced skin carcinogenesis by UV radiation | University of New Mexico | Ke Liu |
Mechanisms of Trinucleotide Repeat Expansion via Oxidative DNA Damage and Repair | Florida International University | Yuan Liu |
Visualization of break-induced replication. | Indiana University-Purdue University at Indianapolis | Kirill Lobachev,; Anna Malkova |
Benzo(a)pyrene Mutagenic Mechanisms | Boston University | Edward Loechler |
The role of human DNA polymerase eta in the mutagenic response to oxidative stress | North Carolina State University Raleigh | Scott McCulloch |
Regulatory Functions of APE1 - An Essential Repair Protein | University of Texas Medical Branch at Galveston | Sankar Mitra |
Mechanism of Mammalian Translesion DNA synthesis | State University New York Stony Brook | Masaaki Moriya |
The contribution of DNA interstrand crosslinks to aging | University of Pittsburgh at Pittsburgh | Laura Niederhofer |
Mechanisms of Telomeric DNA Loss and Repair | University of Pittsburgh at Pittsburgh | Patricia Opresko |
UV damage, repair, and mutagenesis | City of Hope/Beckman Research Institute | Gerd Pfeifer |
Translesion DNA synthesis in humans | University of Texas Medical Branch at Galveston | Louise Prakash |
Role of Rev1 in error-free replication of DNA damage and in mutation prevention | University of Texas Medical Branch at Galveston | Satya Prakash |
Roles of Human DNA Polymerase Epsilon in Mutagenesis and Genome Stability | Tulane University of Louisiana | Zachary Pursell |
Synthesis, Structure and Replication of Carcinogen-Modified Oligonucleotides | Vanderbilt University | Carmelo Rizzo |
A Nested Case-Control Study of Prostate Carcinogenesis | Henry Ford Health System | Benjamin Rybicki |
Mechanisms of DNA Polymerases | New York University | Tamar Schlick |
Oxidative pathways of guanine in DNA | New York University | Vladimir Shafirovich |
Translesion Synthesis DNA Polymerases and Genome Instability | University of Nebraska Medical Center | Polina Shcherbakova |
DNA Repair In A Hormone Responsive Gene | Washington State University | Michael Smerdon |
Pathways to Mutagenesis in vivo and in Stem Cells | University of Cincinnati | Peter Stambrook |
Environmental exposure: Susceptibility alleles in a DNA damage response pathway | University of Cincinnati | Peter Stambrook |
Chemistry and Biology of Carcinogen-DNA Adducts | Vanderbilt University | Michael Stone |
DNA Adducts of Styrene and Other Vinyl Monomers | Vanderbilt University | Michael Stone |
DNA Repair Genes and Proteins of the RAD52 Group | Yale University | Patrick Sung |
Molecular Basis of BRCA2-mediated DNA Repair and Cancer Avoidance | Yale University | Patrick Sung |
DNA Polymerase Beta Variants and Cancer | Yale University | Joann Sweasy |
Adducts as Quantitative Markers of Butadiene Mutagenesis | University of North Carolina Chapel Hill | James Swenberg |
Roles of Lig3 and XRCC1 Genes in Genome Stability | University of Maryland Baltimore | Alan Tomkinson |
Radiation-induced ATM and ERK signaling in DSB repair | Virginia Commonwealth University | Kristoffer Valerie |
Comparative Mechanisms of Genomic Instability | University of Texas MD Anderson Cancer Center | Karen Vasquez |
A Novel Role for the Fanconi Anemia Pathway in Replication of B[a]P-Adducted DNA | University of North Carolina Chapel Hill | Cyrus Vaziri |
Direct Somatic Mutation Analysis Through Sequencing | Albert Einstein College of Medicine at Yeshiva University | Jan Vijg |
Mechanism of Eukaryotic Environmental Mutagenesis | Massachusetts Institute of Technology | Graham Walker |
DNA Damage Responses Following Genotoxin Exposure | Ohio State University | Altaf Wani |
Cross-talking pre-incision events of eukaryotic NER | Ohio State University | Altaf Wani |
Molecular Epidemiology of DNA Repair in Head and Neck Cancer | University of Texas MD Anderson Cancer Center | Qingyi Wei |
Biomarkers of Lung Cancer Susceptibility in Minorities | University of California San Francisco | John Wiencke |
Characterization and testing of novel genes in DNA double-strand break repair | University of California-Lawrence Berkeley Lab | Claudia Wiese |
Environmental Beta Cell Toxins - Mechanisms of Action | University of South Alabama | Glenn Wilson |
A Novel Pathway Involving ATM, PP1 and I-2 | Methodist Hospital Research Institute | Bo Xu |
Defective p53 synthesis following DNA damage and cancer development | Sanford Research/USD | Da-qing Yang |
Genotoxicity of Chromium Compounds | Brown University | Anatoly Zhitkovich |
Microfluidics-assisted display of stretched DNA in the study of DNA repair in viv | University of Washington | Julia Sidorova |
Comet-Chip: A High-Throughput DNA Damage Sensor for Environmental Health Studies | Massachusetts Institute of Technology | Bevin P. Engelward |
