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Your Environment. Your Health.

DNA Repair Research Grantees

Susceptibility & Population Health Branch

NameInstitutionLead Scientist

Role of DNA polymerase eta in errorfree bypass of DNA lesions & cancer prevention

Mount Sinai School of Medicine

Aneel Aggarwal

Biological Effects of DNA Adducts Formed by Nitroaromatic Compounds

University of Connecticut Storrs

Ashis Basu; Zucai Suo

Mechanisms of Environmental and Nuclear and Mitochondrial Mutagenesis

Fred Hutchinson Cancer Research Center

Jason Bielas

Comparing and contrasting the biology of damage survival at a genomic level

University of Texas Health Science Center at San Antonio

Alexander Bishop

Linkage of Lung Inflammation to 8-oxoguanine and OGG1

University of Texas Medical Branch at Galveston

Istvan Boldogh

High Throughput Technology for Assessing Global DSB Repair Capacity

Columbia University Health Sciences

David Brenner

MMR-Coupled Translesion DNA Synthesis During Suppression of PAH-Induced Mutation

Oregon State University

Andrew Buermeyer; John Hays

The Mechanism of Mitochondrial DNA Proofreading in Human Health and Disease

Medical University of South Carolina

Sherine Chan

Regulation of the DNA damage Response

Stanford University

Karlene Cimprich

Identifying Novel Mechanisms and Regulators of Genome Stability

Stanford University

Karlene Cimprich

Cellular Responses to Environmental Insults and Risk for Melanoma Development

University of North Carolina Chapel Hill

Marila Cordeiro-Stone

Molecular Mechanisms of Nitroarene Toxicity

State University New York Stony Brook

Carlos de los Santos

DNA Oxidation Products and Endogenous DNA Adducts

Massachusetts Institute of Technology

Peter Dedon

Inflammation as a Mediator of Dynamic DNA Mutations

Brown University

Sarah Delaney

Cellular Responses to Oxidative Stress in Models of Colon Cancer Development

Emory University

Paul Doetsch

Mouse Models of DNA Repair - Defective Human Diseases

University of Texas Southwestern Medical Center at Dallas

Errol Friedberg

Hypoxia, Genetic Instability and DNA Mismatch Repair

Yale University

Peter Glazer

SWI/SNF chromatin remodeling in nucleotide excision repair

University of Miami School of Medicine

Feng Gong

Biochemical Basis of SOS-Induced Mutagenesis

University of Southern California

Myron Goodman

Nucleoprotein structures formed at sites of DNA damage

University of North Carolina Chapel Hill

Jack Griffith

Cellular Responses to Oxidative Stress in Models of Colon Cancer Development

State University New York Stony Brook

Arthur Grollman

Molecular Biomarkers For Environmental Toxicants

Johns Hopkins University

John Groopman

Polymerase Interactions with Carcinogen-modified DNA

Vanderbilt University

F. Guengerich

Oxidative DNA damage processing; role in human pathology and aging

Stanford University

Philip Hanawalt

Polymorphic variants of human DNA glycosylase NEIL2 and lung cancer susceptibility

University of Texas Medical Branch at Galveston

Tapas Hazra

DNA Adducts of the Carcinogen Acetaldehyde

University of Minnesota Twin Cities

Stephen Hecht

Humanized Mouse Models for the p53 R72P SNP

University of Texas MD Anderson Cancer Center

David Johnson

Modification of DNA Polymerase Delta by a Novel Mechanism During Replication Stre

New York Medical College

Marietta Lee

Arsenic-enhanced skin carcinogenesis by UV radiation

University of New Mexico

Ke Liu

Mechanisms of Trinucleotide Repeat Expansion via Oxidative DNA Damage and Repair

Florida International University

Yuan Liu

Visualization of break-induced replication.

Indiana University-Purdue University at Indianapolis

Kirill Lobachev,; Anna Malkova

Benzo(a)pyrene Mutagenic Mechanisms

Boston University

Edward Loechler

The role of human DNA polymerase eta in the mutagenic response to oxidative stress

North Carolina State University Raleigh

Scott McCulloch

Regulatory Functions of APE1 - An Essential Repair Protein

University of Texas Medical Branch at Galveston

Sankar Mitra

Mechanism of Mammalian Translesion DNA synthesis

State University New York Stony Brook

Masaaki Moriya

The contribution of DNA interstrand crosslinks to aging

University of Pittsburgh at Pittsburgh

Laura Niederhofer

Mechanisms of Telomeric DNA Loss and Repair

University of Pittsburgh at Pittsburgh

Patricia Opresko

UV damage, repair, and mutagenesis

City of Hope/Beckman Research Institute

Gerd Pfeifer

Translesion DNA synthesis in humans

University of Texas Medical Branch at Galveston

Louise Prakash

Role of Rev1 in error-free replication of DNA damage and in mutation prevention

University of Texas Medical Branch at Galveston

Satya Prakash

Roles of Human DNA Polymerase Epsilon in Mutagenesis and Genome Stability

Tulane University of Louisiana

Zachary Pursell

Synthesis, Structure and Replication of Carcinogen-Modified Oligonucleotides

Vanderbilt University

Carmelo Rizzo

A Nested Case-Control Study of Prostate Carcinogenesis

Henry Ford Health System

Benjamin Rybicki

Mechanisms of DNA Polymerases

New York University

Tamar Schlick

Oxidative pathways of guanine  in DNA

New York University

Vladimir Shafirovich

Translesion Synthesis DNA Polymerases and Genome Instability

University of Nebraska Medical Center

Polina Shcherbakova

DNA Repair In A Hormone Responsive Gene

Washington State University

Michael Smerdon

Pathways to Mutagenesis in vivo and in Stem Cells

University of Cincinnati

Peter Stambrook

Environmental exposure:  Susceptibility alleles in a DNA damage response pathway

University of Cincinnati

Peter Stambrook

Chemistry and Biology of Carcinogen-DNA Adducts

Vanderbilt University

Michael Stone

DNA Adducts of Styrene and Other Vinyl Monomers

Vanderbilt University

Michael Stone

DNA Repair Genes and Proteins of the RAD52 Group

Yale University

Patrick Sung

Molecular Basis of BRCA2-mediated DNA Repair and Cancer Avoidance

Yale University

Patrick Sung

DNA Polymerase Beta Variants and Cancer

Yale University

Joann Sweasy

Adducts as Quantitative Markers of Butadiene Mutagenesis

University of North Carolina Chapel Hill

James Swenberg

Roles of Lig3 and XRCC1 Genes in Genome Stability

University of Maryland Baltimore

Alan Tomkinson

Radiation-induced ATM and ERK signaling in DSB repair

Virginia Commonwealth University

Kristoffer Valerie

Comparative Mechanisms of Genomic Instability

University of Texas MD Anderson Cancer Center

Karen Vasquez

A Novel Role for the Fanconi Anemia Pathway in Replication of B[a]P-Adducted DNA

University of North Carolina Chapel Hill

Cyrus Vaziri

Direct Somatic Mutation Analysis Through Sequencing

Albert Einstein College of Medicine at Yeshiva University

Jan Vijg

Mechanism of Eukaryotic Environmental Mutagenesis

Massachusetts Institute of Technology

Graham Walker

DNA Damage Responses Following Genotoxin Exposure

Ohio State University

Altaf Wani

Cross-talking pre-incision events of eukaryotic NER

Ohio State University

Altaf Wani

Molecular Epidemiology of DNA Repair in Head and Neck Cancer

University of Texas MD Anderson Cancer Center

Qingyi Wei

Biomarkers of Lung Cancer Susceptibility in Minorities

University of California San Francisco

John Wiencke

Characterization and testing of novel genes in DNA double-strand break repair

University of California-Lawrence Berkeley Lab

Claudia Wiese

Environmental Beta Cell Toxins - Mechanisms of Action

University of South Alabama

Glenn Wilson

A Novel Pathway Involving ATM, PP1 and I-2

Methodist Hospital Research Institute

Bo Xu

Defective p53 synthesis following DNA damage and cancer development

Sanford Research/USD

Da-qing Yang

Genotoxicity of Chromium Compounds

Brown University

Anatoly Zhitkovich

Microfluidics-assisted display of stretched DNA in the study of DNA repair in viv

University of Washington

Julia Sidorova

Comet-Chip: A High-Throughput DNA Damage Sensor for Environmental Health Studies

Massachusetts Institute of Technology

Bevin P. Engelward

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