R code for fitting Random Periods Model
R code for fitting Random Periods Model - Software Usage Agreement and Download
Developed by:
National Institute of Environmental Health Sciences
Biostatistics Branch
Programmed by Mr. Sai Cheemalapati, Summer Intern 2011, Panther Creek High School
Purpose:
You may use this R code for fitting the Random Periods Model (RPM) for cell cycle genes. Since outliers and influential observations are not uncommon, the parameters of RPM are estimated using the L_1 norm. The RPM is a nonlinear model that can be used to model the expression of a cell-cycle gene over time. For details regarding the model one may refer to Liu et al. (2004).
Software info:
Details on how to use is provided in the README.pdf (63KB)
References:
Liu D, Umbach D, Peddada SD, Li L, Crockett P and Weinberg C (2004). A Random-Periods Model for Expression of Cell-Cycle Genes. Proceedings of National Academy of Sciences, 101, No. 19, 7240-7245.
Download:
CCOptimF.R (6KB)
Contact:
-
Shyamal D. Peddada, Ph.D. (http://www.niehs.nih.gov/research/atniehs/labs/bb/staff/peddada/index.cfm)
Principal Investigator -
Tel (919) 541-1122
Fax (919) 541-4311
peddada@niehs.nih.gov
