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Validation of IMACS tools in Inclusion Body Myositis

Principal Investigator:

Dieter Pongratz, Sabine Krause, et al., Germany


Study Design:

Natural History study


Types & Number of IIM Studied:

Consecutive Inclusion Body Myositis (N = 50)


Entry Criteria:

Griggs et al. 1995 Ann Neurology Inclusion Body Myositis criteria


IMACS Core Set Measures Included:

Physician and Patient Global Activity and Damage Assessments, Manual Muscle Testing, Health Assessment Questionnaire, muscle enzymes, Myositis Disease Activity Assessment Tool; Myositis Damage Index


Other Measures Included:

Magnetic resonance imaging, Quantitative Muscle Testing, NSS


Primary Outcome:



Study Duration:

Evaluation every 6 months for 24 months



Will start early 2005



Sabine Krause, Ph.D.
Dieter Pongratz


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